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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Gram-Negative Infections in Humans and Companion Animals: A Global Threat

edited by

Gabriele Meroni

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1103 | Submission Open

Keywords: antimicrobial resistance; Gram-negative infections; humans; companion animals; essential oils; nanoparticles; pro-biotics; antimicrobial peptides; genomics; metagenomics

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Epidemiology, Impact and Mitigation of Antimicrobial Resistance in Veterinary Medicine, 3rd Edition

edited by

Robin Temmerman

submission deadline 31 Dec 2025 | 1 articles | Viewed by 862 | Submission Open

Keywords: antimicrobial resistance; veterinary medicine; antibiotics; One Health; epidemiology

Combatting Dental Infections: Insights into Oral Microbiota and Antibiotic Therapy

edited by

Biao Ren

and

Jaya Seneviratne

submission deadline 31 Dec 2025 | Viewed by 785 | Submission Open

Keywords: oral microbiota; dental diseases; systematic disease; antimicrobial; therapeutic strategies; oral biomaterials; oral probiotics; infectious disease; oral microecology; targets

Antibiotic Resistance in Agricultural Environments: Emergence, Drivers and Mitigation

edited by

Guyue Cheng

and Juan Wang

submission deadline 31 Dec 2025 | 1 articles | Viewed by 773 | Submission Open

Keywords: antibiotic resistance (AMR); animal husbandry; environmental resistome; livestock microbiome; co-selection; agricultural environments; One Health; antibiotic resistance genes (ARGs); heavy metals; selective pressures

(This special issue belongs to the Section Antibiotics in Animal Health)

Phage Therapy and Antimicrobial Innovation

edited by Ronen Hazan and

Lilach Gavish

submission deadline 31 Dec 2025 | 1 articles | Viewed by 739 | Submission Open

Keywords: antimicrobial resistance (AMR); antimicrobial innovation; phage therapy; phage engineering; synergistic strategies; chronic infections; biofilm; clinical phage microbiology; personalized medicine

(This special issue belongs to the Section Bacteriophages)

Carbapenem-Resistant Acinetobacter baumannii: From Molecular Mechanisms to Clinical Practice

edited by

Antonio Cascio

, David L. Paterson and Luca Pipitò

submission deadline 31 Dec 2025 | Viewed by 623 | Submission Open

Keywords: CRAB; XDR; MDR; Acinetobacter baumannii; antimicrobial resistance; molecular mechanisms; clinical practice

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial Resistance in the Wildlife

edited by

Francesca Piras

and Giuliana Siddi

submission deadline 31 Dec 2025 | 1 articles | Viewed by 548 | Submission Open

Keywords: wildlife; wild animal; antimicrobial resistance; transmission; spread; One Health

Advances in Antimicrobial Compounds: Exploring Natural, Synthetic, and Repositioned Drugs

edited by

Alessia Carocci

and Alexia Barbarossa

submission deadline 31 Dec 2025 | 1 articles | Viewed by 530 | Submission Open

Keywords: antimicrobial compounds; natural products; synthetic agents; drug repositioning; antimicrobial resistance; synergistic approaches; mechanisms of action; drug development

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Global Trends in Antimicrobial Resistance: Epidemiology and Public Health Implications

edited by Louise Teixeira Cerdeira

submission deadline 31 Dec 2025 | Viewed by 375 | Submission Open

Keywords: antimicrobial resistance (AMR); antibiotic misuse; global health; epidemiology; antibiotic stewardship

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Global Perspectives on Antimicrobial Stewardship and Food Safety

edited by

Mahmoud Eltholth

submission deadline 31 Dec 2025 | Viewed by 352 | Submission Open

Keywords: antimicrobial resistance; antimicrobial use; food systems; food safety; antimicrobial stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotic Resistance in Geriatric Emergency Patients: Challenges and Strategies for Optimal Management

edited by

Sung Jin Bae

and

Dong-Hoon Lee

submission deadline 31 Dec 2025 | Viewed by 318 | Submission Open

Keywords: antibiotic resistance; geriatric emergency medicine; antimicrobial stewardship; multidrug-resistant organisms

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Biofilms and Implantable Device-Related Infections

edited by

Felipe Francisco Tuon

submission deadline 31 Dec 2025 | Viewed by 215 | Submission Open

Keywords: biofilm formation; implant-associated infections; medical devices; antimicrobial resistance; infection prevention

Antimicrobial Resistance Surveillance Methods: Challenges and Opportunities

edited by Samo Jeverica

submission deadline 31 Dec 2025 | Viewed by 193 | Submission Open

Keywords: antimicrobial resistance; AMR surveillance; One Health; infectious diseases; global health

Machine Learning for Antimicrobial Resistance Prediction, 2nd Edition

edited by

Asad Mustafa Karim

submission deadline 10 Jan 2026 | 2 articles | Viewed by 5756 | Submission Open

Keywords: antimicrobial resistance prediction; artificial intelligence; machine learning; infectious diseases

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Rational Use of Antibiotics in Veterinary Medicine

edited by

JeongWoo Kang

submission deadline 15 Jan 2026 | 2 articles | Viewed by 9488 | Submission Open

Keywords: good manufacturing practice (GMP) in antibiotic production; research and systems in antibiotic quality control; consequences of improper antibiotic use; antibiotic stewardship programs; antibiotic resistance management

(This special issue belongs to the Section Antibiotics in Animal Health)

Antibiotic Resistance: The Role of Aquatic Environments

edited by

Jason W. Marion

and Matthew D. Stocker

submission deadline 15 Jan 2026 | 2 articles | Viewed by 4111 | Submission Open

Keywords: antibiotic resistance; water; wastewater; One Health; antibiotic misuse; antimicrobial resistance genes; microbiology; fecal indicator bacteria; mobile genetic elements; resistome; pollution; environment; water bodies; water treatment; waterborne disease; public health; risk assessment; sanitation; hygiene; aquatic environments

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

The Discovery of Novel Beta-Lactams and Beta-Lactamase Inhibitors

edited by

Caitlyn Thomas

and

Juhee Ahn

submission deadline 15 Jan 2026 | Viewed by 393 | Submission Open

Keywords: antibiotic resistance; β -lactam antibiotics; β -lactamase inhibitors; drug discovery; metallo-β -lactamases; serine-β -lactamase

Strategies for Combating Antibiotic Resistance: From Mechanisms to Drug Discovery

edited by Angel Leon-Buitimea

submission deadline 15 Jan 2026 | Viewed by 251 | Submission Open

Keywords: antibiotic resistance; clinically relevant bacteria; multidrug-resistant bacteria; pan-drug-resistant bacteria; drug discovery; combinatorial treatments

Advances in Antimicrobial Treatment of Periodontitis

edited by

Thomas E. Rams

submission deadline 15 Jan 2026 | Viewed by 204 | Submission Open

Keywords: periodontitis; periodontal chemotherapy; anti-infective periodontal therapy; antibiotic therapy

Molecular and Therapeutic Insights into Antimicrobial Candidates and Antibiotics

edited by

Fabio Aguiar Alves

and

Bruno de Araujo Penna

submission deadline 15 Jan 2026 | Viewed by 189 | Submission Open

Keywords: antimicrobial resistance; novel antimicrobial agents; molecular mechanisms; therapeutic applications

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

New Insights into Prevention, Diagnosis, and Treatment of Neonatal Sepsis and Short- and Long-Term Outcomes

edited by

Vasilios Giapros

Dimitrios Rallis

and Maria Baltogianni

submission deadline 20 Jan 2026 | 2 articles | Viewed by 5196 | Submission Open

Keywords: neonate; sepsis; early sepsis; late sepsis; antibiotic resistance; multiple resistance antibiotics; antibiotics stewardship

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotic Use and Stewardship in Settings Outside of Acute Hospitals

edited by Monsey McLeod and Naomi Fleming

submission deadline 30 Jan 2026 | 1 articles | Viewed by 510 | Submission Open

Keywords: antimicrobial stewardship; antibiotic use; community; primary care; mental health; local authority; care home; public; health and justice; dental

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Discovery and Synthesis of Antimicrobial Compounds Against Multidrug Resistance

edited by

Anita Cohen

submission deadline 31 Jan 2026 | 4 articles | Viewed by 42860 | Submission Open

Keywords: antimicrobial resistance; medicinal chemistry; (pre)clinical development; intrinsic/synergistic activity; innovative antibiotic treatment; antimicrobial drug-candidate; new and repurposed medicines

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotic Resistance in Wastewater Treatment Plants

edited by Qingbin Yuan

submission deadline 31 Jan 2026 | 5 articles | Viewed by 9307 | Submission Open

Keywords: antibiotic resistance genes; wastewater treatment; one health; distribution and removal of ARGs; horizontal gene transfer

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Multidrug-Resistant Gram-Negative Bacteria Infections: Current Epidemiology, Prognosis and Treatment Options

edited by Novella Carannante

submission deadline 31 Jan 2026 | 5 articles | Viewed by 8735 | Submission Open

Keywords: multidrug-resistant gram-negative bacteria; epidemiology and prognosis; antibiotic treatment options; antimicrobial resistance; infection control and antibiotic use

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Microbial Biofilms: Identification, Resistance and Novel Drugs

edited by

Célia Fortuna Rodrigues

and

Susana Patrícia Lopes

submission deadline 31 Jan 2026 | 3 articles | Viewed by 8070 | Submission Open

Keywords: biofilm; resistance; pathogens; alternative treatment; plant extract; peptides; nanotechnology

(This special issue belongs to the Section Antibiofilm Strategies)

Advances in the Field of Biofilm-Associated Musculoskeletal Infections

edited by

Kordo Saeed

submission deadline 31 Jan 2026 | 4 articles | Viewed by 8053 | Submission Open

Keywords: musculoskeletal infections; biofilm-associated; mycobacterial-associated; implant-related infections

(This special issue belongs to the Section Antibiofilm Strategies)

Challenges and Strategies for the Antibiotic Resistance Crisis

edited by

Manuel Simões

and

Marc Maresca

submission deadline 31 Jan 2026 | 4 articles | Viewed by 7102 | Submission Open

Keywords: antibiotics stewardship; antimicrobial use; antibiotics resistance; novel antimicrobial agents; multidisciplinary antimicrobial strategies; antibiotic clinical studies; artificial intelligence strategies

Single-Stage Management of Musculo-Skeletal Infections: Local Antibacterial Protection, Antibiotics, and Surgical Treatments

edited by

Guillem Bori

and

Carlo L. Romanò

submission deadline 31 Jan 2026 | 3 articles | Viewed by 6784 | Submission Open

Keywords: knee arthroplasty; hip arthroplasty; shoulder arthroplasty; antibiotic treatment; one-stage revision arthroplasty; antibacterial coating

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

The Appropriateness of Antibiotic Prescribing in Hospitals and Ambulatory Care

edited by

Francesco Ferrara

, Roberto Langella and

Andrea Zovi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 5733 | Submission Open

Keywords: pharmacology; antimicrobic resistance; governance; appropriateness; infectivology

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Mechanisms of Microbial Biofilm Resistance and New Methods for Biofilm Control

edited by

Gianmarco Mangiaterra

submission deadline 31 Jan 2026 | 1 articles | Viewed by 5325 | Submission Open

Keywords: quorum sensing; chronic infections; antibiotic resistance; persistence; efflux pumps

(This special issue belongs to the Section Antibiofilm Strategies)

Tracking Reservoirs of Antimicrobial Resistance Genes in Environment

edited by

Mor Nadia Lurie-Weinberger

and

Dror Avisar

submission deadline 31 Jan 2026 | 3 articles | Viewed by 5226 | Submission Open

Keywords: antimicrobial resistance; AMR; environmental reservoirs; antibiotic resistance genes; ARGs; horizontal gene transfer

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antifungal Strategies: Epidemiological Approaches, Mechanisms and Resistance in Fungal Pathogens

edited by

Erick Martinez-Herrera

Rodolfo Pinto-Almazán

and

Carmen Rodríguez-Cerdeira

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3963 | Submission Open

Keywords: antifungal strategies; epidemiology; antifungal resistance; antifungal mechanisms; resistance genes

(This special issue belongs to the Section Fungi and Their Metabolites)

The Antibiotic Resistance and Virulence Genes of Pathogens in Aquatic and Soil Environment

edited by

Bing Li

submission deadline 31 Jan 2026 | 1 articles | Viewed by 3112 | Submission Open

Keywords: antibiotic resistance genes (ARGs); virulence genes; pathogenic bacteria; horizontal gene transfer

Antimicrobial Stewardship in Surgical Infection

edited by Nuno Rocha-Pereira

submission deadline 31 Jan 2026 | 3 articles | Viewed by 2274 | Submission Open

Keywords: antimicrobial stewardship; surgical infection; surgical site infection; antimicrobial resistance; diagnostic stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Advances in Antimicrobial Therapies for Oral Infections: From Biofilm Disruption to Clinical Applications

edited by

Cláudia Helena Silva-Lovato

and

Adriana Barbosa Ribeiro

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1313 | Submission Open

Keywords: oral infections; microbial biofilm; antimicrobial therapies

(This special issue belongs to the Section Antibiofilm Strategies)

Diagnostics and Antibiotic Therapy in Bone and Joint Infections

edited by Sebastian Meller and Stavros Goumenos

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1045 | Submission Open

Keywords: bone and joint infections; osteomyelitis; implant-related infections; diagnostics; antimicrobials; antibiotic therapy; PJI management; surgical site antisepsis; local antibiotic therapy; diagnostic biomarkers; multidisciplinary infection management; outcome analysis after musculoskeletal infection

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Helicobacter pylori Virulence Factors, Antibiotic Susceptibility and Persistent Infection

edited by

Mara Di Giulio

Teresa Fasciana

and

Chiara Pagliuca

submission deadline 31 Jan 2026 | 1 articles | Viewed by 882 | Submission Open

Keywords: Antimicrobial drugs and therapies; virulence factors; pathogenesis; extra-digestive diseases; gastric microbioma

Bacterial Infections and Global Health: The Escalating Threat of Antibiotic Resistance

edited by

Nicola Petrosillo

and

Guido Granata

submission deadline 31 Jan 2026 | Viewed by 515 | Submission Open

Keywords: infection control; antimicrobial stewardship; spread of multidrug-resistant bacteria; methicillin-resistant Staphylococcus aureus; carbapenemases; metallo-β -Lactamase; microbiology diagnostics in field hospitals; One Health

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial Resistance Genes: Spread and Evolution, 2nd Edition

edited by

Angeliki Mavroidi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 508 | Submission Open

Keywords: microbes; antimicrobial resistance; resistance genes; gene flow; evolution

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Dermatological Infections and Antibiotic Treatment

edited by

Oriana Simonetti

submission deadline 31 Jan 2026 | Viewed by 482 | Submission Open

Keywords: dermatological infections; antibiotic resistance; antibiotics; antibiotic treatment

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

A Themed Issue in Honor of Prof. Dr. Fausto Catena—Outstanding Contributions in the Fields of Antibiotics in the Acute Care and Emergency

edited by Carlo Vallicelli

submission deadline 31 Jan 2026 | Viewed by 435 | Submission Open

Keywords: emergency surgery; intra-abdominal infections; antibiotic treatment; trauma surgery; sepsis

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Foodborne Pathogens: The Rise of Virulence and Antimicrobial Resistance

edited by

Luisa Brito

and

Acacio Salamandane

submission deadline 31 Jan 2026 | Viewed by 388 | Submission Open

Keywords: foodborne pathogens; antimicrobial resistance; virulence factors; food chain; antibiotic overuse; public health; food safety; zoonotic diseases; one health

A Themed Issue in Honor of Professor Aditya Gupta—Outstanding Contributions to Antifungal Therapy, Dermatology and Mycology

edited by Ditte Marie Saunte and Mesbah Talukder

submission deadline 31 Jan 2026 | Viewed by 324 | Submission Open

Keywords: onychomycosis; antifungal resistance; dermatophyte infections; antifungal stewardship; Trichophyton indotineae; topical and oral antifungals; treatment algorithms; epidemiology of onychomycosis

Molecular Diagnostics and Antimicrobial Resistance in Animal Pathogens

edited by Mariela E. Srednik and

Volker Krömker

submission deadline 31 Jan 2026 | Viewed by 314 | Submission Open

Keywords: antimicrobial susceptibility; molecular diagnostic; antimicrobial resistance; animal pathogens; bacterial diseases

(This special issue belongs to the Section Antibiotics in Animal Health)

Nanoparticles as Novel Solutions to Microbial Resistance in Hospital Care

edited by

Zdenka Bedlovičová

submission deadline 31 Jan 2026 | Viewed by 307 | Submission Open

Keywords: nanoparticles; antibiotic resistance; nosocomial infections; MRSA; VRSA; antimicrobial properties; multi-drug resistance

(This special issue belongs to the Section Antimicrobial Materials and Surfaces)

Superbugs Unleashed: Global Challenges and Solutions for Extensively Drug-Resistant and Pan-Drug-Resistant Pathogens

edited by

Ionela-Larisa Miftode

submission deadline 31 Jan 2026 | Viewed by 280 | Submission Open

Keywords: antimicrobial resistance; extensively drug-resistant pathogens; pan-drug-resistant bacteria; multidrug-resistant organisms (MDROs); infectious disease control; antibiotic stewardship; novel antimicrobials; rapid diagnostics; global health threats

Neonatal Infection: Antibiotics for Prevention and Treatment

edited by Cinzia Auriti and Maria Paola Ronchetti

submission deadline 31 Jan 2026 | Viewed by 278 | Submission Open

Keywords: neonatal infections; neonatal sepsis; sepsis definition; antibiotics in newborns; antibiotic stewardship; sepsis biomarkers; sepsis diagnosis in newborns; epidemiology of neonatal infections; fungal invasive infections

Advances in the Diagnosis and Antibiotic Treatments of Diabetic Foot Infections

edited by

Francisco Javier Álvaro-Afonso

and

Éric M. Senneville

submission deadline 31 Jan 2026 | Viewed by 257 | Submission Open

Keywords: diabetic foot; diabetic foot ulcer; diabetic foot osteomyelitis; antibiotics; treatment

Membrane Disruptors: The Role of Antimicrobial Peptides in Combatting Pathogens

edited by

Andrea Mescola

submission deadline 31 Jan 2026 | Viewed by 250 | Submission Open

Keywords: antimicrobial peptides (AMPs); microbial resistance; drug-resistant pathogens; anticancer; antiviral; membrane disruption; membrane poration; permeabilization; lipids; peptide design and engineering

(This special issue belongs to the Section Antimicrobial Peptides)

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