Strategies for Combating Antibiotic Resistance: From Mechanisms to Drug Discovery
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: 15 January 2026 | Viewed by 55
Special Issue Editor
Special Issue Information
Dear Colleagues,
Antibiotic resistance represents a critical global health crisis that is severely impacting our ability to treat infections. The increasing prevalence of multidrug-resistant and pan-drug-resistant bacteria necessitates an urgent search for novel therapeutic strategies to safeguard public health.
This Special Issue will highlight the importance of exploring diverse approaches, including the discovery of new antimicrobial compounds with mechanisms of action capable of overcoming existing resistance. Furthermore, it will emphasize the potential of combination therapies in enhancing the effectiveness of current antibiotics, restoring their activity against resistant strains, and hindering the development of further resistance. Understanding the intricate molecular mechanisms driving antibiotic resistance will also be a central theme, as this knowledge is crucial in rationalizing innovative therapeutic interventions and identifying novel drug targets.
This Special Issue will provide a comprehensive overview of ongoing efforts to combat antibiotic resistance, from fundamental mechanistic studies to the development and implementation of new therapeutic strategies. We hope to contribute to the global fight against this significant public health threat by bringing together the latest research in this vital area.
Dr. Angel Leon-Buitimea
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antibiotic resistance
- clinically relevant bacteria
- multidrug-resistant bacteria
- pan-drug-resistant bacteria
- drug discovery
- combinatorial treatments
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