BioMedInformatics, Volume 2, Issue 4

In recent years, the advent of new experimental methodologies for studying the high complexity of the human genome and proteome has led to the generation of an increasing amount of digital information, hence bioinformatics, which harnesses computer s...

Behavioral factors can affect the blood glucose (BG) levels in people with type 1 diabetes (T1D), therefore, their effects need to be incorporated in blood glucose management for these individuals. Accordingly, in this work, we study the effect of tw...

Feature selection is a common step in data preprocessing that precedes machine learning to reduce data space and the computational cost of processing or obtaining the data. Filtering out uninformative variables is also important for knowledge discove...

Photorefractive keratectomy (PRK) has long been the method of choice for refractive surgery in pilots, and was FDA approved for U.S. Air Force aviators in 2000. We retrospectively reviewed the medical records of 16 male combat pilots (mean age 25.0 &...

Breast carcinoma (BCa) remains the second most common cause of cancer-related death among American women. Whereas estrogen receptor (ER) expression is typically regarded as a favorable prognostic indicator, a significant proportion of ER(+) patients...

Individualized, serial production of innovative implants is a major area of application for additive manufacturing in the field of medicine. Individualized healthcare requires faster delivery of the implant to the clinic or hospital facility. The tot...

Accurate and early detection of causes of pneumonia is important for implementing fast treatment and preventive strategies, reducing the burden of infections, and establishing more effective ways of interventions. After the outbreak of COVID-19, the...

Mitochondrial DNA (mtDNA) damage is closely associated with typical diseases of aging, such as Alzheimer’s or Parkinson’s disease, and other health conditions, such as infertility. This damage manifests in reduced mitochondrial copy numbe...

Background: High-quality oligonucleotides for molecular amplification and detection procedures of diverse target sequences depend on sequence homology. Processing input sequences and identifying homogeneous regions in alignments can be carried out by...

The retinal degenerative disease retinitis pigmentosa (RP) is a genetic disease that is the most common cause of blindness in adults. In 2016, Chow et. al. identified over 100 candidate modifier genes for RP through the genome-wide analysis of 173 in...