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Diabetology, Volume 7, Issue 5

2026 May - 19 articles

Cover Story: Consistent offloading is essential for healing diabetic foot ulcers (DFUs), yet adherence remains a persistent challenge. In this 8-patient substudy of a 210-patient cohort, adults used SmartBoot, a sensor-integrated offloading device paired with a smartwatch running the CORA app. The app delivered schedule-based prompts and context-aware prompts triggered when sensors detected unprotected weight-bearing. Among notifications delivered during non-adherence, context-aware prompts produced a 74.6% behavioral response rate within 60 min, compared with 34.8% for scheduled prompts. Patients wore boots an average of 3.5 h longer on notification days, and six of the eight achieved complete wound healing. These findings support sensor-triggered feedback and justify a powered evaluation to improve offloading adherence in DFU care. View this paper
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Articles (19)

  • Article
  • Open Access
1 Citations
724 Views
36 Pages

Background: Pre-existing diabetes mellitus is prevalent among critically ill adults and can influence initial glycemic targets, therapeutic decisions, and early risk stratification in the intensive care unit (ICU). However, diabetes status may be dis...

  • Commentary
  • Open Access
931 Views
8 Pages

From Device Data to Trusted Decision Support: Building the Foundation for AI in Hospital Insulin Management

  • Mandy M. Shao,
  • Agatha F. Scheideman,
  • Casey Rand,
  • David C. Klonoff and
  • Juan Espinoza

The adoption of artificial intelligence (AI) tools for hospital insulin management is currently limited by data fragmentation and difficult integration into clinical workflows. This commentary examines the data infrastructure requirements for safe AI...

(This article belongs to the Special Issue Diabetes Management in the Hospital: Applications of Artificial Intelligence)
  • Article
  • Open Access
670 Views
10 Pages

Diabetes in Secondary Care in The Netherlands: The Study Design of a Comprehensive Analysis of Claims and Demographic Data—DUDE (DUtch Diabetes Estimates)—10

  • Peter R. van Dijk,
  • Marije van Zanten,
  • Mireille A. Edens,
  • Frank Ardesch,
  • Arianne M. J. Elissen,
  • Jan Westerink,
  • Dirk Ruwaard and
  • Henk J. G. Bilo

Background: Obtaining reliable and detailed information about the population of individuals with diabetes mellitus (DM) in The Netherlands remains a persistent challenge. Previous studies used primary care coding and extrapolations to estimate the co...

  • Review
  • Open Access
1,036 Views
12 Pages

High Diabetes Prevalence and Implications for Progress Toward SDG 3: An Umbrella Review of Four African Countries

  • Addisu Tadesse Sahile,
  • Mussie Wubshet Teka and
  • Azwihangwisi Helen Mavhandu-Mudzusi

Background: Diabetes mellitus (DM) is an emerging public health challenge in Africa, driven by rapid urbanisation, changing lifestyles and socio-economic transitions. As the global prevalence rises, evidence on the burden and determinants of DM acros...

(This article belongs to the Special Issue Advances in Diabetes: Prevalence, Risk Factors, Complications, Costs and Disparities)
  • Article
  • Open Access
1,592 Views
15 Pages

Can a Chatbot Help Heal a Wound? Context-Aware Prompts for Boosting Adherence in Diabetic Foot Ulcers

  • Aria Rabet,
  • Aminreza Khandan,
  • Arian Rabet,
  • Mohammad Dehghan Rouzi,
  • Fabiola Rodriguez,
  • Adriana Garibay,
  • David G. Armstrong and
  • Bijan Najafi

Background: Smart offloading technologies enable the real-time, objective monitoring of adherence in patients with diabetic foot ulcers (DFUs). Although remote tracking may reinforce adherence and improve wound healing, effectiveness depends on susta...

(This article belongs to the Special Issue Advances in Diabetic Wound Healing: From Mechanisms to Therapies)
  • Article
  • Open Access
1 Citations
946 Views
17 Pages

Monitoring Diabetic Foot Using Images and Generative AI

  • Afonso Nobre and
  • João Silva Sequeira

Background: Diabetic Foot Ulcers (DFU) are a common complication of diabetes, often leading to infections, amputations and even death if left untreated. Effective management of the Diabetic Foot (DF) requires timely detection and frequent monitoring....

(This article belongs to the Special Issue All Toes Considered for Diabetic Foot: Prevention, Treatment, and Healthcare Policy)
  • Article
  • Open Access
978 Views
11 Pages

A Pragmatic Cluster-Randomized Trial of Insulin Therapy for Dexamethasone-Induced Hyperglycemia Amongst Diabetes Patients with COVID-19

  • Ngai Wah Cheung,
  • Amanda Hor,
  • Simone Marschner,
  • Christopher Chan,
  • Haeri Min,
  • Lauren Lee,
  • Tien-Ming Hng,
  • Yoon Ji Jina Rhou,
  • Yu-Fang Wu and
  • David R. Chipps
  • + 1 author

Background: Glucocorticoid-induced hyperglycemia is common amongst hospitalized patients. Isophane insulin has been proposed as part of the optimal insulin regimen for managing this, but there are few randomized controlled trials to support this. Our...

(This article belongs to the Special Issue Advances in Inpatient Diabetes Care)
  • Review
  • Open Access
3,325 Views
25 Pages

Diabetes and Gastroparesis: New Concepts and Insights

  • Gaetano Leto,
  • Pietro Crispino,
  • Antonello Viceconti and
  • Valentina Camardo

Diabetic gastroparesis (DGp) is a chronic complication of diabetes characterized by delayed gastric emptying with nausea, vomiting, early satiety, bloating, and poor glycemic control. Diagnosis requires objective testing, preferably a 4-h gastric emp...

  • Article
  • Open Access
2,984 Views
14 Pages

Life’s Essential 8 and Risk of Type 2 Diabetes in the Women’s Health Initiative

  • Andrea J. Glenn,
  • Joseph C. Larson,
  • Ellie Hsu,
  • Hind A. Beydoun,
  • Michael J. LaMonte,
  • Lisa Warsinger Martin,
  • Anna C. Rivara,
  • Jean Wactawski-Wende,
  • Thomas E. Rohan and
  • Lesley F. Tinker
  • + 10 authors

Objective: To examine the association between Life Essential 8 (LE8) and incident T2D in the Women’s Health Initiative (WHI), and to assess whether associations varied by race and ethnicity. Research Design and Methods: Prospective cohort study...

(This article belongs to the Special Issue Diabetes Prevention and Management: Diet, Physical Activity and Lifestyle Behaviors)
  • Review
  • Open Access
1,425 Views
18 Pages

This review aims to present an updated, comprehensive analysis of data on the diversity and challenges of current approaches to the screening and monitoring of subjects at risk of T1D, as the earliest interventions during the course of the disease. P...

(This article belongs to the Special Issue Early Intervention and Treatment Strategies for Diabetes)
  • Review
  • Open Access
2,009 Views
25 Pages

Simplifying Treatment for Type 2 Diabetes: Egyptian Consensus Recommendations on Fixed-Ratio Combinations

  • Samir H. Assaad-Khalil,
  • Talaat Abdelaaty,
  • Mary N. Rizk,
  • Magdy Helmy Megallaa,
  • Mohamed Elsayed,
  • Alaa M. Wafa,
  • Azza Ismail,
  • Bahaa Sharafeldeen and
  • Noha G. Amin

Background/Objectives: Egypt ranks among the top ten countries globally with the highest burden of type 2 diabetes mellitus (T2DM), with prevalence projected to rise significantly by 2050. Despite multiple therapeutic options, glycemic control remain...

  • Article
  • Open Access
1,093 Views
16 Pages

Adherence to the 24 h Movement Guidelines and Type 2 Diabetes Risk in the SUN Project: A Prospective Cohort Study

  • Alejandro Fernandez-Montero,
  • Alexander Finnemore,
  • Anne Gribble,
  • María Llavero-Valero,
  • Francisco J. Basterra-Gortari,
  • Maira Bes-Rastrollo and
  • Miguel Ángel Martínez-Gonzalez

Background: Type 2 diabetes (T2D) is a leading chronic disease worldwide. Physical activity, sedentary time and sleep are modifiable risk factors for T2D that share the same 24 h time budget. The 24 h Movement Guidelines propose an integrated approac...

(This article belongs to the Special Issue Exercise as Medicine: Exploring the Prevention and Management of Diabetes)
  • Article
  • Open Access
1,322 Views
14 Pages

Photodynamic Therapy as an Adjunctive Approach for Diabetic Foot Osteomyelitis: A Prospective Case Series

  • João Antonio Correa,
  • Sofia Torres Velloso,
  • Luciene do Nascimento Lima,
  • Patricia Paola Cagol,
  • Julia Yamanaka Agnelo,
  • Gustavo Lolli,
  • João Paulo Tardivo,
  • Rafael Carvalho de Vilhena Furst,
  • Gabriela Tessaro Cremoneis and
  • Rodrigo Daminello Raimundo

Introduction: Type 2 diabetes mellitus predisposes patients to neuropathy, peripheral arterial disease, and diabetic foot ulcers, which may become infected and progress to osteomyelitis, increasing the risk of amputation. The growing prevalence of mu...

(This article belongs to the Special Issue Advances in Diabetic Wound Healing: From Mechanisms to Therapies)
  • Article
  • Open Access
1,167 Views
14 Pages

Background/Objectives: Diabetes is a prevalent chronic condition and a major contributor to morbidity, mortality, and healthcare costs in the U.S., particularly among older adults with comorbidities such as hypertension and dyslipidemia. Complex medi...

(This article belongs to the Special Issue Efficacy, Safety and Real-World Evidence of Hypoglycemic Drugs)
  • Article
  • Open Access
1,436 Views
20 Pages

Background/Objectives: To examine the association of social determinants of health (SDOHs) with primary and cost-related medication nonadherence among adults with diabetes. Methods: A retrospective cross-sectional analysis was conducted using 2021 da...

(This article belongs to the Special Issue Advances in Diabetes: Prevalence, Risk Factors, Complications, Costs and Disparities)
  • Review
  • Open Access
1,794 Views
17 Pages

Diabetic kidney disease (DKD) remains a primary driver of end-stage kidney disease and cardiovascular morbidity despite the optimized use of renin–angiotensin system (RAS) inhibitors and sodium-glucose cotransporter-2 (SGLT2) inhibitors. Recent...

(This article belongs to the Special Issue New Insights into the Diagnosis, Prevention and Treatment of Diabetic Complications)
  • Article
  • Open Access
1,171 Views
14 Pages

Waist Circumference and Handgrip Strength as Potential Nursing Vital Signs in Type 2 Diabetes: A Preliminary Assessment

  • Barbara Gómez-Taylor,
  • Jorge Casaña Mohedo,
  • Alma María Palau-Ferrè,
  • Rocío Práxedes Gómez,
  • Aáron Quesada Hernández,
  • Ernesto Navarro Escobar,
  • Elena Sandri and
  • Sara Morales Palomares

Background and aims: The aim of this study was to examine the relationships between muscle function, dietary quality, body composition markers, and metabolic status in ambulatory patients with type 2 diabetes. The study sought to validate low-cost to...

  • Review
  • Open Access
1,393 Views
8 Pages

Sodium glucose-1 cotransporter (SGLT1) is a low-capacity, high-affinity glucose transporter expressed in the proximal renal tubule. It is also expressed in different human tissues and, primarily, in the brush border of the small intestine. At this le...

(This article belongs to the Special Issue Early Intervention and Treatment Strategies for Diabetes)
  • Article
  • Open Access
1,173 Views
19 Pages

Accelerometer-Measured Physical Activity and Its Association with Metabolic Markers of Type 2 Diabetes Mellitus: A Cross-Sectional NHANES Study

  • Sophia C. Bremer,
  • Rodrigo D. Raimundo,
  • Andrey A. Porto,
  • David M. Garner,
  • Luana P. Oliveira,
  • Caroline S. Ferrari,
  • Edilaine A. Nascimento,
  • Sandra Maria Barbalho and
  • Vitor E. Valenti

Background: We aimed to study the association between accelerometer-measured physical activity and metabolic markers of diabetes in a nationwide representative sample of U.S. adults. Methods: This cross-sectional analysis included 1259 adults aged &g...

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Diabetology - ISSN 2673-4540