2026 October - 22 articles
Background: Natural mineral water (NMW) is a heterogeneous dietary exposure whose composition varies substantially among sources. Objective: This critical review examines human intervention evidence on NMW in relation to metabolic health across healt...
Background: India bears one of the highest diabetes burdens globally, yet community-based evidence simultaneously examining the contributions of dietary adherence and physical activity to glycaemic control remains scarce. Most existing Indian studies...
Background/Objectives: Achieving glycaemic control remains challenging in patients with type 2 diabetes mellitus (T2DM). Fixed-dose combinations with complementary mechanisms may facilitate treatment intensification and improve adherence. This study...
Background: In the Australian Capital Territory (ACT) during the Coronavirus disease 2019 (COVID-19) pandemic, gestational diabetes mellitus (GDM) testing using the World Health Organization’s (WHO) oral glucose tolerance test (OGTT) was replac...
Background: Hospital inpatient hypoglycaemia is a common complication associated with poor patient outcomes. With the rising prevalence of diabetes mellitus (DM) and approximately 20% of hospital beds occupied by patients with DM, inpatient hypoglyca...
Background: Patients with type 1 diabetes complicated by severe hypoglycemia and impaired awareness remain at high risk of mortality despite advances in diabetes treatment. Pancreas transplantation offers definitive β-cell replacement; however,...
Health literacy challenges are associated with greater risk and adverse outcomes of long-term conditions such as diabetes mellitus and contribute to persistent health inequalities. In response, increasing attention has been given to Organisational He...
Objectives: This study aimed to develop a structured and culturally appropriate diabetes education platform to provide accessible education to individuals and caregivers of Type 1 Diabetes (T1D). Methods: In phase I, the digital tele-education platfo...
Background/Objectives: In this retrospective aggregate pharmacovigilance study, we described UK Yellow Card reporting relative to partial English National Health Service (NHS) general practice (GP) prescribing for six glucagon-like peptide-1 (GLP-1)-...
Background: ABCC8 gene variants have been linked to a range of conditions that affect insulin secretion, such as congenital hyperinsulinism, neonatal diabetes and maturity-onset diabetes of the young (MODY). This study aimed to characterise ABCC...
Background/Objectives: Sleep health contributes to glucose homeostasis and metabolic regulation. We explored associations between subjective sleep characteristics, glycemic control, and diabetes-related clinical factors in adults with type 1 diabetes...
Background: Hospital readmission among patients with diabetes remains a healthcare challenge, contributing to adverse clinical outcomes, increased healthcare expenditures, and reduced quality of care. This study presents a leakage-resistant and clini...
Background/Objectives: Diabetic foot disease is associated with high rates of ulceration, amputation and premature mortality. While biomedical risk factors are systematically assessed in clinical practice, non-biomedical determinants—psychologi...
Type 2 diabetes (T2D) is increasingly recognized as a systemic network disorder in which impaired communication among endocrine, neural, immune, and microbial systems drives metabolic dysfunction and accelerates biological aging. Extending DeFronzo&r...
Objective: Obesity and type 2 diabetes mellitus frequently coexist and require therapeutic strategies capable of addressing both excess adiposity and cardiometabolic risk. However, real-world evidence on whether improvements in cardiometabolic parame...
Diabetic wound healing is characterised by persistent inflammation, impaired angiogenesis, extracellular matrix (ECM) dysregulation, and defective tissue remodelling, frequently resulting in chronic wounds such as diabetic foot ulcers (DFUs). Fibrosi...
The prevalences of overweight, obesity, prediabetes, and diabetes are rapidly increasing worldwide, accompanied by increased insulin resistance (IR). Although the proportions of these populations vary greatly by region, a common trend across all area...
PDX-1 and MafA are insulin gene transcription factors and maintain mature pancreatic β-cell function. After chronic exposure to hyperglycemia, however, the expression levels of PDX-1 and MafA are substantially suppressed by provoked oxidative st...
Background/Objectives: This study aimed to assess the effect of tirzepatide on systemic inflammation in a diabetic neuropathy (DN) model in mice. Methods: Type 1 diabetes was induced with streptozotocin 180 mg/kg i.p. One month later, we injected two...
Background: Semaglutide and tirzepatide are not approved for type 1 diabetes (T1D), and their real-world effects on insulin requirements, metabolic outcomes, and safety are uncertain. Methods: Using de-identified electronic health record data from a...
Diabetes mellitus is increasingly recognized as a disorder of skeletal quality in addition to metabolic dysregulation. Both type 1 and type 2 diabetes are associated with increased fracture risk, impaired fracture healing, and higher rates of orthope...
Type 1 diabetes (T1D) is an autoimmune disease in which genetic susceptibility interacts with environmental and immunometabolic factors. Growing evidence implicates gut dysbiosis, impaired intestinal barrier integrity, and altered microbial metabolit...
