Table of Contents
Vet. Sci., Volume 5, Issue 4 (December 2018)
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Cover Story (view full-size image) In 1997, a paradigm shift occurred when it was recognized that AIV could be transmitted directly [...] Read more. In 1997, a paradigm shift occurred when it was recognized that AIV could be transmitted directly from poultry to humans. Because of our increased awareness, thousands of cases of AIV in humans was documented. The first human cases of H9N2 subtype of AIV was in 1999, and sporadic cases have been reported over the last 20 years. This article summarizes multiple studies that examine the risk of H9N2 virus in humans. Serologic studies in humans in poultry-endemic countries show high seroprevalence in poultry-exposed workers, suggesting a high infection rate. Fortunately, H9N2 AIV have only been reported in cases of respiratory disease and not systemic disease with mortality. Influenza viruses by their nature can change rapidly, and we need to monitor these viruses in the hope of preventing or mitigating the next human pandemic. View this paper