You are currently viewing a new version of our website. To view the old version click .

Bioengineering, Volume 9, Issue 5

May 2022 - 51 articles

Cover Story: The aim of regenerative medicine is to regrow functional tissues by manipulating exogenous or endogenous cells. Genetic engineering is one such strategy that directs cells to form the desired tissue. Among the various viral and nonviral techniques to achieve gene delivery, sonoporation has shown promising results in preclinical studies. Using ultrasound and microbubbles, sonoporation introduces genetic material to cells, leading to cell differentiation and subsequent tissue regeneration. Since it induces transient gene expression, sonoporation is considered safer compared to viral vectors, although less efficient. More research on the mode of action and the enhancement of ultrasound systems is required to optimize the therapeutic potential of sonoporation and pave its way into the clinical setting. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (51)

  • Article
  • Open Access
8 Citations
4,069 Views
20 Pages

A Deep Learning Approach for the Morphological Recognition of Reactive Lymphocytes in Patients with COVID-19 Infection

  • José Rodellar,
  • Kevin Barrera,
  • Santiago Alférez,
  • Laura Boldú,
  • Javier Laguna,
  • Angel Molina and
  • Anna Merino

Laboratory medicine plays a fundamental role in the detection, diagnosis and management of COVID-19 infection. Recent observations of the morphology of cells circulating in blood found the presence of particular reactive lymphocytes (COVID-19 RL) in...

  • Article
  • Open Access
10 Citations
6,240 Views
15 Pages

Poly(3-mercapto-2-methylpropionate), a Novel α-Methylated Bio-Polythioester with Rubber-like Elasticity, and Its Copolymer with 3-hydroxybutyrate: Biosynthesis and Characterization

  • Lucas Vinicius Santini Ceneviva,
  • Maierwufu Mierzati,
  • Yuki Miyahara,
  • Christopher T. Nomura,
  • Seiichi Taguchi,
  • Hideki Abe and
  • Takeharu Tsuge

A new polythioester (PTE), poly(3-mercapto-2-methylpropionate) [P(3M2MP)], and its copolymer with 3-hydroxybutyrate (3HB) were successfully biosynthesized from 3-mercapto-2-methylpropionic acid as a structurally-related precursor. This is the fourth...

  • Review
  • Open Access
16 Citations
7,403 Views
12 Pages

Cervical and Lumbar Disc Arthroplasty: A Review of Current Implant Design and Outcomes

  • Ian J. Wellington,
  • Cameron Kia,
  • Ergin Coskun,
  • Barrett B. Torre,
  • Christopher L. Antonacci,
  • Michael R. Mancini,
  • John P. Connors,
  • Sean M. Esmende and
  • Heeren S. Makanji

While spinal disc pathology has traditionally been treated using fusion-based procedures, recent interest in motion-preserving disc arthroplasties has grown. Traditional spinal fusion is associated with loss of motion, alteration of native spine kine...

  • Review
  • Open Access
8 Citations
4,697 Views
22 Pages

Applications of Photodynamic Therapy in Endometrial Diseases

  • Gabriela Correia-Barros,
  • Beatriz Serambeque,
  • Maria João Carvalho,
  • Carlos Miguel Marto,
  • Marta Pineiro,
  • Teresa M. V. D. Pinho e Melo,
  • Maria Filomena Botelho and
  • Mafalda Laranjo

Photodynamic therapy (PDT) is a medical procedure useful for several benign conditions (such as wound healing and infections) and cancer. PDT is minimally invasive, presents few side effects, good scaring, and is able to minimal tissue destruction ma...

  • Review
  • Open Access
65 Citations
12,316 Views
24 Pages

Review of the Developments of Bacterial Medium-Chain-Length Polyhydroxyalkanoates (mcl-PHAs)

  • V. Uttej Nandan Reddy,
  • S. V. Ramanaiah,
  • M. Venkateswar Reddy and
  • Young-Cheol Chang

Synthetic plastics derived from fossil fuels—such as polyethylene, polypropylene, polyvinyl chloride, and polystyrene—are non-degradable. A large amount of plastic waste enters landfills and pollutes the environment. Hence, there is an ur...

  • Article
  • Open Access
3 Citations
3,294 Views
9 Pages

Background: Although spinopelvic radiographs analysis is the standard for a pathological diagnosis, it cannot explain the activities of the spine in daily life. This study investigates the correlation between sagittal parameters and spinal range of m...

  • Review
  • Open Access
13 Citations
4,346 Views
15 Pages

Growth factors are bio-factors that target reparatory cells during bone regeneration. These growth factors are needed in complicated conditions of bone and joint damage to enhance tissue repair. The delivery of these growth factors is key to ensuring...

  • Article
  • Open Access
19 Citations
3,625 Views
15 Pages

Partial denitrification, the termination of NO3−-N reduction at nitrite (NO2−-N), has received growing interest for treating wastewaters with high ammonium concentrations, because it can be coupled to anammox for total-nitrogen removal. N...

  • Article
  • Open Access
15 Citations
3,171 Views
11 Pages

Mechanical and Metallurgical Evaluation of 3 Different Nickel-Titanium Rotary Instruments: An In Vitro and In Laboratory Study

  • Alessio Zanza,
  • Paola Russo,
  • Rodolfo Reda,
  • Paola Di Matteo,
  • Orlando Donfrancesco,
  • Pietro Ausiello and
  • Luca Testarelli

An in-depth evaluation of the mechanical and metallurgical properties of NiTi instruments is fundamental to assess their performance and to compare recently introduced instrument with widespread ones. According to this, since there are no data on thi...

  • Review
  • Open Access
6 Citations
5,468 Views
41 Pages

MatriGrid® Based Biological Morphologies: Tools for 3D Cell Culturing

  • Patrick Mai,
  • Jörg Hampl,
  • Martin Baca,
  • Dana Brauer,
  • Sukhdeep Singh,
  • Frank Weise,
  • Justyna Borowiec,
  • André Schmidt,
  • Johanna Merle Küstner and
  • Maren Klett
  • + 7 authors

Recent trends in 3D cell culturing has placed organotypic tissue models at another level. Now, not only is the microenvironment at the cynosure of this research, but rather, microscopic geometrical parameters are also decisive for mimicking a tissue...

of 6

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Bioengineering - ISSN 2306-5354Creative Common CC BY license