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Bioengineering, Volume 9, Issue 6

2022 June - 35 articles

Cover Story: Thrombosis is main complication in patients supported with ventricular assist devices (VADs). In this study, an improved thrombotic model that integrates shear stress, coagulation factors, and residence time as well as flow obstruction caused by thrombus formation was constructed to assess thrombotic potential of three clinical VADs (CH-VAD, HVAD, and HMII). The regions of high thrombotic risk predicted by this thrombosis model were highly consistent with experimental and clinical statistical results. The secondary flow passage of CH-VAD, hydrodynamic clearance between rotor and casing in HVAD, the front guide region, and blade top clearance of HMII are regions with high thrombus incidence. View this paper
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Articles (35)

  • Article
  • Open Access
3 Citations
2,659 Views
9 Pages

Physiological Ventricular Simulator for Valve Surgery Training

  • Kasparas Zilinskas,
  • Jennie H. Kwon,
  • Katherine Bishara,
  • Kaila Hayden,
  • Ritchelli Quintao and
  • Taufiek Konrad Rajab

Surgical simulation is becoming increasingly important in training cardiac surgeons. However, there are currently no training simulators capable of testing the quality of simulated heart valve procedures under dynamic physiologic conditions. Here we...

  • Review
  • Open Access
9 Citations
8,929 Views
12 Pages

Pathophysiology of Cerebral Malaria: Implications of MSCs as A Regenerative Medicinal Tool

  • Amrendra Chaudhary,
  • Poonam Kataria,
  • Neha Surela and
  • Jyoti Das

The severe form of malaria, i.e., cerebral malaria caused by Plasmodium falciparum, is a complex neurological syndrome. Surviving persons have a risk of behavioral difficulties, cognitive disorders, and epilepsy. Cerebral malaria is associated with m...

  • Article
  • Open Access
4 Citations
2,969 Views
19 Pages

Phenotypes of Motor Deficit and Pain after Experimental Spinal Cord Injury

  • Volodymyr Krotov,
  • Volodymyr Medvediev,
  • Ibrahim Abdallah,
  • Arseniy Bozhenko,
  • Mykhailo Tatarchuk,
  • Yevheniia Ishchenko,
  • Leonid Pichkur,
  • Serhii Savosko,
  • Vitaliy Tsymbaliuk and
  • Nana Voitenko
  • + 1 author

Motor disability is a common outcome of spinal cord injury (SCI). The recovery of motor function after injury depends on the severity of neurotrauma; motor deficit can be reversible, at least partially, due to the innate tissue capability to recover,...

  • Article
  • Open Access
35 Citations
4,940 Views
16 Pages

BM-Net: CNN-Based MobileNet-V3 and Bilinear Structure for Breast Cancer Detection in Whole Slide Images

  • Jin Huang,
  • Liye Mei,
  • Mengping Long,
  • Yiqiang Liu,
  • Wei Sun,
  • Xiaoxiao Li,
  • Hui Shen,
  • Fuling Zhou,
  • Xiaolan Ruan and
  • Cheng Lei
  • + 3 authors

Breast cancer is one of the most common types of cancer and is the leading cause of cancer-related death. Diagnosis of breast cancer is based on the evaluation of pathology slides. In the era of digital pathology, these slides can be converted into d...

  • Article
  • Open Access
7 Citations
3,448 Views
11 Pages

Effectiveness of the REvision System and Sonic Irrigation in the Removal of Root Canal Filling Material from Oval Canals: An In Vitro Study

  • Marc Krikor Kaloustian,
  • Claire El Hachem,
  • Carla Zogheib,
  • Walid Nehme,
  • Louis Hardan,
  • Pamela Rached,
  • Naji Kharouf,
  • Youssef Haikel and
  • Davide Mancino

This study aimed to evaluate the effectiveness of the Endostar REvision system (Poldent, Warsaw, Poland) in the removal of filling materials from oval root canals using sonic irrigation as an additional cleaning method. Thirty human-extracted mandibu...

  • Article
  • Open Access
15 Citations
4,400 Views
15 Pages

Biomechanical Analysis of the Use of Stems in Revision Total Knee Arthroplasty

  • Bernardo Innocenti,
  • Edoardo Bori and
  • Silvia Pianigiani

Adequate fixation is fundamental in revision total knee arthroplasty; consequently, surgeons must determine the correct set-up for each patient, choosing from numerous stem solutions. Several designs are currently available on the market, but there a...

  • Article
  • Open Access
6 Citations
2,593 Views
11 Pages

Odor released from the sewage sludge composting process often has a negative impact on the sewage sludge treatment facility and becomes a hindrance to promoting compost technology. This study investigated the effect of adding KNO3 on the emissions of...

  • Article
  • Open Access
3 Citations
3,603 Views
11 Pages

Dynamic Foam Characteristics during Cultivation of Arthrospira platensis

  • Ameer Ali Kubar,
  • Amjad Ali,
  • Santosh Kumar,
  • Shuhao Huo,
  • Muhammad Wajid Ullah,
  • Khulood Fahad Saud Alabbosh,
  • Muhammad Ikram and
  • Jun Cheng

This study is aimed at understanding the serious foaming problems during microalgal cultivation in industrial raceway ponds by studying the dynamic foam properties in Arthrospira platensis cultivation. A. platensis was cultivated in a 4 L bowl biorea...

  • Article
  • Open Access
24 Citations
3,767 Views
13 Pages

A Comparison of Computer-Aided Diagnosis Schemes Optimized Using Radiomics and Deep Transfer Learning Methods

  • Gopichandh Danala,
  • Sai Kiran Maryada,
  • Warid Islam,
  • Rowzat Faiz,
  • Meredith Jones,
  • Yuchen Qiu and
  • Bin Zheng

Objective: Radiomics and deep transfer learning are two popular technologies used to develop computer-aided detection and diagnosis (CAD) schemes of medical images. This study aims to investigate and to compare the advantages and the potential limita...

  • Article
  • Open Access
13 Citations
2,675 Views
17 Pages

Simulating In Vitro the Bone Healing Potential of a Degradable and Tailored Multifunctional Mg-Based Alloy Platform

  • Victor Martin,
  • Mónica Garcia,
  • Maria de Fátima Montemor,
  • João Carlos Salvador Fernandes,
  • Pedro Sousa Gomes and
  • Maria Helena Fernandes

This work intended to elucidate, in an in vitro approach, the cellular and molecular mechanisms occurring during the bone healing process, upon implantation of a tailored degradable multifunctional Mg-based alloy. This was prepared by a conjoining an...

  • Article
  • Open Access
7 Citations
4,113 Views
12 Pages

A Liquid Metal-Enhanced Wearable Thermoelectric Generator

  • Wei Liu,
  • Zhenming Li,
  • Yanfang Yang,
  • Chengbo Hu,
  • Zhen Wang and
  • Yongling Lu

It is a key challenge to continuously power personal wearable health monitoring systems. This paper reports a novel liquid metal-enhanced wearable thermoelectric generator (LM-WTEG that directly converts body heat into electricity for powering the we...

  • Article
  • Open Access
7 Citations
2,749 Views
14 Pages

Many communication standards have been proposed recently and more are being developed as a vision for dynamically composable and interoperable medical equipment. However, few have security systems that are sufficiently extensive or flexible to meet c...

  • Review
  • Open Access
34 Citations
6,367 Views
18 Pages

Assessment and Scientific Progresses in the Analysis of Olfactory Evoked Potentials

  • Pasquale Arpaia,
  • Andrea Cataldo,
  • Sabatina Criscuolo,
  • Egidio De Benedetto,
  • Antonio Masciullo and
  • Raissa Schiavoni

The human sense of smell is important for many vital functions, but with the current state of the art, there is a lack of objective and non-invasive methods for smell disorder diagnostics. In recent years, increasing attention is being paid to olfact...

  • Review
  • Open Access
26 Citations
7,857 Views
15 Pages

Nisin Variants Generated by Protein Engineering and Their Properties

  • Yue Zheng,
  • Yuhui Du,
  • Zekai Qiu,
  • Ziming Liu,
  • Jianjun Qiao,
  • Yanni Li and
  • Qinggele Caiyin

Nisin, a typical lantibiotic, has robust antimicrobial activity combined with limited cytotoxicity, and the development of resistance to it is slow. These properties make nisin a promising antimicrobial agent to control pathogenic microorganisms in d...

  • Review
  • Open Access
34 Citations
9,448 Views
31 Pages

Biodegradable and Biocompatible Adhesives for the Effective Stabilisation, Repair and Regeneration of Bone

  • Antzela Tzagiollari,
  • Helen O. McCarthy,
  • Tanya J. Levingstone and
  • Nicholas J. Dunne

Bone defects and complex fractures present significant challenges for orthopaedic surgeons. Current surgical procedures involve the reconstruction and mechanical stabilisation of complex fractures using metal hardware (i.e., wires, plates and screws)...

  • Review
  • Open Access
26 Citations
6,081 Views
15 Pages

A Review of Additive Manufacturing Studies for Producing Customized Ankle-Foot Orthoses

  • Rui Silva,
  • António Veloso,
  • Nuno Alves,
  • Cristiana Fernandes and
  • Pedro Morouço

Ankle-foot orthoses (AFO) are prescribed to improve the patient’s quality of life. Supporting weak muscles or restraining spastic muscles leads to smoother and more stable locomotion. Commonly, AFO are made using thermoplastic vacuum forming, w...

  • Article
  • Open Access
2 Citations
4,340 Views
16 Pages

Enhancing Prednisone-Based Arthritis Therapy with Targeted IL-27 Gene Delivery

  • Adriana A. Marin,
  • Richard E. Decker,
  • Shreya Kumar,
  • Zachary Lamantia,
  • Hiroki Yokota,
  • Todd Emrick and
  • Marxa L. Figueiredo

Rheumatoid arthritis (RA) is a chronic autoimmune disease which is characterized primarily by synovial hyperplasia and accumulation of several types of immune infiltrates that promote progressive destruction of the articular structure. Glucocorticoid...

  • Article
  • Open Access
10 Citations
5,427 Views
12 Pages

Microfluidic-Based Novel Optical Quantification of Red Blood Cell Concentration in Blood Flow

  • Yudong Wang,
  • Bharath Babu Nunna,
  • Niladri Talukder and
  • Eon Soo Lee

The optical quantification of hematocrit (volumetric percentage of red blood cells) in blood flow in microfluidic systems provides enormous help in designing microfluidic biosensing platforms with enhanced sensitivity. Although several existing metho...

  • Article
  • Open Access
9 Citations
4,198 Views
10 Pages

Understanding Sex-Based Kinematic and Kinetic Differences of Chasse-Step in Elite Table Tennis Athletes

  • Xiaoyi Yang,
  • Qichang Mei,
  • Shirui Shao,
  • Wenjing Gu,
  • Yuqi He,
  • Ruizhe Zhu and
  • Yaodong Gu

With the progress and innovation of table tennis technology, individualized training programs may deserve special attention. This study aimed to analyze elite table tennis athletes in chasse-step, with a particular focus on sex-based biomechanical di...

  • Review
  • Open Access
18 Citations
3,571 Views
9 Pages

Contribution of Tumor-Derived Extracellular Vesicles to Malignant Transformation of Normal Cells

  • Daria S. Chulpanova,
  • Tamara V. Pukhalskaia,
  • Albert A. Rizvanov and
  • Valeriya V. Solovyeva

Tumor-cell-derived extracellular vesicles (EVs) are known to carry biologically active molecules of parental cells, which can actively modulate the tumor microenvironment. EVs produced by tumor cells play significant roles in the development and main...

  • Article
  • Open Access
9 Citations
3,848 Views
11 Pages

Quality Management of Pulmonary Nodule Radiology Reports Based on Natural Language Processing

  • Xiaolu Fei,
  • Pengyu Chen,
  • Lan Wei,
  • Yue Huang,
  • Yi Xin and
  • Jia Li

To investigate the feasibility of automated follow-up recommendations based on findings in radiology reports, this paper proposed a Natural Language Processing model specific for Pulmonary Nodule Radiology Reports. Unstructured findings used to descr...

  • Review
  • Open Access
31 Citations
5,354 Views
19 Pages

The Footprint of Exosomes in the Radiation-Induced Bystander Effects

  • Safura Jokar,
  • Inês A. Marques,
  • Saeedeh Khazaei,
  • Tania Martins-Marques,
  • Henrique Girao,
  • Mafalda Laranjo and
  • Maria Filomena Botelho

Radiation therapy is widely used as the primary treatment option for several cancer types. However, radiation therapy is a nonspecific method and associated with significant challenges such as radioresistance and non-targeted effects. The radiation-i...

  • Article
  • Open Access
12 Citations
5,246 Views
25 Pages

3D Bioprinting of Prevascularized Full-Thickness Gelatin-Alginate Structures with Embedded Co-Cultures

  • Bastian Böttcher,
  • Astrid Pflieger,
  • Jan Schumacher,
  • Berit Jungnickel and
  • Karl-Heinz Feller

The use of bioprinting allows the creation of complex three-dimensional cell laden grafts with spatial placements of different cell lines. However, a major challenge is insufficient nutrient transfer, especially with the increased size of the graft c...

  • Article
  • Open Access
9 Citations
4,433 Views
12 Pages

The Influence of a Shoe’s Heel-Toe Drop on Gait Parameters during the Third Trimester of Pregnancy

  • Xin Li,
  • Zhenghui Lu,
  • Dong Sun,
  • Rongrong Xuan,
  • Zhiyi Zheng and
  • Yaodong Gu

Background: Changes in physical shape and body mass during pregnancy may increase the risk of walking falls. Shoes can protect and enhance the inherent function of the foot, helping to maintain dynamic and static stability. Methods: Sixteen women dur...

  • Article
  • Open Access
34 Citations
6,324 Views
29 Pages

Decellularized Human Umbilical Tissue-Derived Hydrogels Promote Proliferation and Chondrogenic Differentiation of Mesenchymal Stem Cells

  • Faiza Ramzan,
  • Sobia Ekram,
  • Trivia Frazier,
  • Asmat Salim,
  • Omair Anwar Mohiuddin and
  • Irfan Khan

Tissue engineering is a promising approach for the repair and regeneration of cartilaginous tissue. Appropriate three-dimensional scaffolding materials that mimic cartilage are ideal for the repair of chondral defects. The emerging decellularized tis...

  • Article
  • Open Access
6 Citations
8,736 Views
16 Pages

Simplified Convolutional Neural Network Application for Cervix Type Classification via Colposcopic Images

  • Vitalii Pavlov,
  • Stanislav Fyodorov,
  • Sergey Zavjalov,
  • Tatiana Pervunina,
  • Igor Govorov,
  • Eduard Komlichenko,
  • Viktor Deynega and
  • Veronika Artemenko

The inner parts of the human body are usually inspected endoscopically using special equipment. For instance, each part of the female reproductive system can be examined endoscopically (laparoscopy, hysteroscopy, and colposcopy). The primary purpose...

  • Article
  • Open Access
26 Citations
7,266 Views
17 Pages

Reconstruction of Soft Biological Tissues Using Laser Soldering Technology with Temperature Control and Biopolymer Nanocomposites

  • Alexander Yu. Gerasimenko,
  • Elena A. Morozova,
  • Dmitry I. Ryabkin,
  • Alexey Fayzullin,
  • Svetlana V. Tarasenko,
  • Victoria V. Molodykh,
  • Evgeny S. Pyankov,
  • Mikhail S. Savelyev,
  • Elena A. Sorokina and
  • Dmitry V. Telyshev
  • + 2 authors

Laser soldering is a current biophotonic technique for the surgical recovery of the integrity of soft tissues. This technology involves the use of a device providing laser exposure to the cut edges of the wound with a solder applied. The proposed sol...

  • Article
  • Open Access
3 Citations
3,390 Views
9 Pages

Traditional qPCR instrument is combined with CMOS and a personal computer, and a photoelectric feedback automatic fluorescence detection system is designed to realize quantitative real-time PCR. The key to reaction efficiency lies in how to ensure th...

  • Review
  • Open Access
19 Citations
7,806 Views
9 Pages

Healthcare providers have acknowledged the dangers of radiation exposure to embryonic and fetal health, yet diagnostic imaging of pregnant women is increasing. Literature that pertains to the topic of interest was reviewed to collect tertiary data. T...

  • Article
  • Open Access
29 Citations
4,869 Views
19 Pages

A New Mathematical Numerical Model to Evaluate the Risk of Thrombosis in Three Clinical Ventricular Assist Devices

  • Yuan Li,
  • Hongyu Wang,
  • Yifeng Xi,
  • Anqiang Sun,
  • Xiaoyan Deng,
  • Zengsheng Chen and
  • Yubo Fan

(1) Background: Thrombosis is the main complication in patients supported with ventricular assist devices (VAD). Models that accurately predict the risk of thrombus formation in VADs are still lacking. When VADs are clinically assisted, their complex...

  • Article
  • Open Access
10 Citations
5,001 Views
9 Pages

The Schroth exercise can train the paraspinal muscles of patients with adolescent idiopathic scoliosis (AIS), however, muscle performance during the training remains unknown. This study applied surface electromyography (sEMG) to investigate the paras...

  • Review
  • Open Access
23 Citations
9,598 Views
21 Pages

The healing of deep skin wounds is a complex phenomenon evolving according with a fine spatiotemporal regulation of different biological events (hemostasis, inflammation, proliferation, remodeling). Due to the spontaneous evolution of damaged human d...

  • Article
  • Open Access
19 Citations
4,865 Views
16 Pages

Highly Porous Type II Collagen-Containing Scaffolds for Enhanced Cartilage Repair with Reduced Hypertrophic Cartilage Formation

  • Claudio Intini,
  • Tom Hodgkinson,
  • Sarah M. Casey,
  • John P. Gleeson and
  • Fergal J. O’Brien

The ability to regenerate damaged cartilage capable of long-term performance in an active joint remains an unmet clinical challenge in regenerative medicine. Biomimetic scaffold biomaterials have shown some potential to direct effective cartilage-lik...

  • Article
  • Open Access
37 Citations
7,039 Views
16 Pages

EEG-Based Emotion Recognition Using a 2D CNN with Different Kernels

  • Yuqi Wang,
  • Lijun Zhang,
  • Pan Xia,
  • Peng Wang,
  • Xianxiang Chen,
  • Lidong Du,
  • Zhen Fang and
  • Mingyan Du

Emotion recognition is receiving significant attention in research on health care and Human-Computer Interaction (HCI). Due to the high correlation with emotion and the capability to affect deceptive external expressions such as voices and faces, Ele...

  • Editorial
  • Open Access
4 Citations
2,463 Views
7 Pages

In recent years, both cardiology and cardiovascular surgery have witnessed an era of consistently evolving changes which have dramatically transformed the course and management of cardiovascular disease [...]

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Bioengineering - ISSN 2306-5354