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Special Issue "Extracellular Matrix in Musculoskeletal Regeneration"
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Regenerative Engineering".
Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 9600
Special Issue Editors
Interests: muscle aging; cell–matrix interactions; integrin-mediated signaling; myoblast fusion; regenerative rehabilitation in skeletal muscle trauma
Interests: MicroCT imaging; orthopedic and dental implantology; breast cancer metastasis to bone; small animal model surgery
Special Issue Information
The overall focus of this Special Issue is on the influence of the extracellular matrix to regulate musculoskeletal health and regeneration in cases of osteoarthritis, osteopenia, sarcopenia, and other musculoskeletal trauma. The extracellular matrix influences stem cell behavior through its physical structure, available ligands, and source of growth factors. Moreover, the extracellular matrix has the ability to sequester and facilitate specific packaging of extracellular vesicles, making it a potent regulator of stem cell proliferation and differentiation. Recent advances in synthetic and naturally derived biomaterials allow us to study the translational and transformative aspects of the extracellular matrix in musculoskeletal regeneration, especially when attempting to regenerate tissue in austere microenvironments related to disease or trauma.
This Special Issue on “Extracellular Matrix in Musculoskeletal Regeneration” is open for original papers and reviews investigating extracellular matrix biology in normal, diseased, or injured bone, cartilage, or skeletal muscle. Topics and themes for this collection will include but are not limited to the following:
- Tissue-specific extracellular matrix scaffolds used to regenerate bone, cartilage, or skeletal muscle;
- Extracellular matrix-mediated stem cell differentiation in musculoskeletal tissue;
- Biophysical properties of extracellular matrix and its effect on musculoskeletal stem cells;
- Extracellular vesicles derived from bone, cartilage, or muscle to drive stem cell fate;
- Synthetic and natural derived biomimetic extracellular matrix scaffolds used in bone, cartilage, or skeletal muscle regeneration;
- Influence of bone, cartilage, or skeletal muscle crosstalk signaling on extracellular matrix and regeneration;
- Microfluidic devices used to identify extracellular matrix-related changes due to tissue crosstalk.
Dr. Michael J. Mcclure
Prof. Joshua Cohen
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- extracellular matrix
- extracellular vesicles
- surface modifications
- skeletal muscle