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Separations, Volume 8, Issue 12

December 2021 - 23 articles

Cover Story: New sputtered carbon SPME fibers showed similar functional group selectivity as commercial CWR fibers, where the sputtered morphology has again shown the ability to overcome phase thickness/volume discrepancies and increase the relative recovery for some compounds. Additionally, a new SPME evaluation mix was developed, which consists of 15 compounds with different functional groups and chemical properties. Pentane, chloroform, 2-picoline, and sulfolane provided valuable insights into coating/stationary phase behavior, which would otherwise have been missed by the traditional probe mixes. N,N-dimethylamine and dicyclohexylamine, which are present in the Kovats’ and Grob’s test mixes, continue to show their value in the current study. The sputtered carbon fibers showed better responses per volume of the coatings than commercial CWR fibers. View this paper.
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Articles (23)

  • Article
  • Open Access
16 Citations
5,163 Views
13 Pages

18 December 2021

The aim of this work was to develop a new method for the determination of selected substances from the date-rape drugs group: ketamine, benzodiazepines and cocaine. The method is based on the dried blood spot method which seems to be a suitable tool...

  • Article
  • Open Access
15 Citations
4,033 Views
19 Pages

How Coffee Capsules Affect the Volatilome in Espresso Coffee

  • Giuseppe Greco,
  • Estefanía Núñez-Carmona,
  • Marco Abbatangelo,
  • Patrizia Fava and
  • Veronica Sberveglieri

17 December 2021

Coffee capsules have become one of the most used methods to have a coffee in the last few years. In this work, coffee was prepared using a professional espresso coffee machine. We investigated the volatilome of four different polypropylene coffee cap...

  • Article
  • Open Access
5 Citations
3,083 Views
11 Pages

16 December 2021

Polycyclic aromatic hydrocarbon (PAH) derivatives are mutagenic, carcinogenic, teratogenic and bioaccumulative pollutants. Investigations on hydroxylated PAHs (OH–PAHs) and Nitrated PAHs (NPAHs) in surface water are not enough. In this study, o...

  • Article
  • Open Access
1 Citations
2,527 Views
11 Pages

14 December 2021

Efficient separation of pharmaceuticals and metabolites with the adequate resolution is a key factor in choosing the most suitable chromatographic method. For quality control, the analysis time is a key factor, especially in pharmacokinetic studies....

  • Article
  • Open Access
52 Citations
7,729 Views
14 Pages

Effect of Ultrasound-Assisted Pretreatment on Extraction Efficiency of Essential Oil and Bioactive Compounds from Citrus Waste By-Products

  • Harloveleen Kaur Sandhu,
  • Prachi Sinha,
  • Neela Emanuel,
  • Nishant Kumar,
  • Rokayya Sami,
  • Ebtihal Khojah and
  • Amina A. M. Al-Mushhin

13 December 2021

Waste or by-product use is in focus for reducing the environmental threat and acquiring wealth out of waste. The current study aim was to investigate the effects of ultrasound pretreatment on the extraction of bioactive compounds and composition of e...

  • Article
  • Open Access
9 Citations
3,709 Views
15 Pages

Hemp Chemotype Definition by Cannabinoids Characterization Using LC-ESI(+)-LTQ-FTICR MS and Infrared Multiphoton Dissociation

  • Filomena Lelario,
  • Raffaella Pascale,
  • Giuliana Bianco,
  • Laura Scrano and
  • Sabino Aurelio Bufo

13 December 2021

The development and application of advanced analytical methods for a comprehensive analysis of Cannabis sativa L. extracts plays a pivotal role in order to have a reliable evaluation of their chemotype definition to guarantee the efficacy and safety...

  • Feature Paper
  • Article
  • Open Access
37 Citations
5,959 Views
9 Pages

Green Stability Indicating Organic Solvent-Free HPLC Determination of Remdesivir in Substances and Pharmaceutical Dosage Forms

  • Adel Ehab Ibrahim,
  • Sami El Deeb,
  • Emad Mahmoud Abdelhalim,
  • Ahmed Al-Harrasi and
  • Rania Adel Sayed

12 December 2021

A green liquid chromatographic method is considered in this work to minimize the environmental impact of waste solvents. One important principle is to replace or eliminate the use of hazardous organic solvents. Organic impurities in any active pharma...

  • Article
  • Open Access
8 Citations
4,207 Views
14 Pages

10 December 2021

Coal is the dominant energy resource in China. With the Chinese policy of committing to reducing peak carbon dioxide emissions and achieving carbon neutrality, coal separation has recently become a hot topic, especially the fluidized separation of fi...

  • Article
  • Open Access
3,340 Views
13 Pages

Isolation and Purification of a Hydrophobic Non-Ribosomal Peptide from an Escherichia coli Fermentation Broth

  • Arne Michael Oestreich,
  • Sebastian Reinhardt,
  • Doreen Gerlach,
  • Rong Fan and
  • Peter Czermak

Non-ribosomal peptide synthases (NRPSs) generate versatile bioactive peptides by incorporating non-proteinogenic amino acids and catalyzing diverse modifications. Here, we developed an efficient downstream process for the capture, intermediate purifi...

  • Article
  • Open Access
6 Citations
3,976 Views
14 Pages

A rapid, simple, and sensitive gas chromatography–tandem mass spectrometry (GC–MS) method was established and validated for simultaneous determination of four volatile compounds, namely curzerene, methoxyfuranodiene, β-elemene, and &...

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Separations - ISSN 2297-8739