You are currently on the new version of our website. Access the old version .

Processes, Volume 12, Issue 2

2024 February - 185 articles

Cover Story: This manuscript introduces CrossTx, a novel computational method for predicting drug transcriptomic responses in unseen target cell lines. CrossTx combines a Predictor step, which produces cell-line-agnostic drug signatures from reference datasets like the Connectivity Map (CMap), with a Corrector step, which projects these signatures onto the transcriptomic latent space of the target cell lines. The application to the CMap dataset highlights the high prediction accuracy achieved by combining an averaging technique as a Predictor with principal component analysis and an autoencoder as a Corrector. CrossTx is an efficacious tool for advancing drug discovery, drug repurposing, and personalized medicine. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (185)

  • Article
  • Open Access
1 Citations
2,211 Views
17 Pages

19 February 2024

The thermal characteristics of the spindle system for CNC machine tools are influenced by multiple factors which are nonlinear and time-varying. In this paper, a nonlinear time-varying thermal characteristics solving model for the spindle system was...

  • Article
  • Open Access
6 Citations
2,198 Views
16 Pages

Prediction of Energy Consumption in a Coal-Fired Boiler Based on MIV-ISAO-LSSVM

  • Jiawang Zhang,
  • Xiaojing Ma,
  • Zening Cheng and
  • Xingchao Zhou

19 February 2024

Aiming at the problem that the energy consumption of the boiler system varies greatly under the flexible peaking requirements of coal-fired units, an energy consumption prediction model for the boiler system is established based on a Least-Squares Su...

  • Article
  • Open Access
4 Citations
2,350 Views
18 Pages

Cooling Damage Characterization and Chemical-Enhanced Oil Recovery in Low-Permeable and High-Waxy Oil Reservoirs

  • Xuanran Li,
  • Lun Zhao,
  • Ruijie Fei,
  • Jincai Wang,
  • Shanglin Liu,
  • Minghui Li,
  • Shujun Han,
  • Fujian Zhou and
  • Shuai Yuan

19 February 2024

The well productivity of high-waxy reservoirs is highly influenced by temperature changes. A decrease in temperature can cause the precipitation of wax from the crude oil, leading to a decrease in the formation’s drainage capacity and a drop in...

  • Article
  • Open Access
2 Citations
1,907 Views
17 Pages

19 February 2024

At present, there have been a number of hydrogen storage tank explosions in hydrogen filling stations, causing casualties and property losses, and having a bad social impact. This has made people realize that the risk assessment and preventive mainte...

  • Article
  • Open Access
1 Citations
1,743 Views
13 Pages

19 February 2024

Bioglycerol is a major by-product of the biodiesel manufacturing process. Various chemical derivatives from bioglycerol would enhance its economic value. An antifreeze of glycerine acetate was chemically converted from an esterification reaction of b...

  • Feature Paper
  • Article
  • Open Access
2 Citations
1,595 Views
15 Pages

19 February 2024

The impact of particle addition jets on the flow field in natural gas pipelines was investigated, and the structural information of the flow field at different flow velocities in a symmetric jet flow was analyzed via numerical simulation. The results...

  • Review
  • Open Access
32 Citations
6,690 Views
28 Pages

19 February 2024

Dry machining has gained significant importance in the last few years due to its promising contribution towards sustainability. This review study introduces dry machining, presents its benefits, and summarizes the recent technological developments th...

  • Article
  • Open Access
2 Citations
2,489 Views
26 Pages

Exploring the Antimelanoma Potential of Betulinic Acid Esters and Their Liposomal Nanoformulations

  • Andreea Milan,
  • Marius Mioc,
  • Alexandra Mioc,
  • Narcisa Marangoci,
  • Roxana Racoviceanu,
  • Gabriel Mardale,
  • Mihaela Bălan-Porcărașu,
  • Slavița Rotunjanu,
  • Irina Şoica and
  • Codruța Șoica

19 February 2024

Betulinic acid is a naturally occurring pentacyclic triterpene belonging to the lupane-group that exhibits a wide range of pharmacological activities. BA derivatives are continuously being researched due to their improved anticancer efficacy and bioa...

  • Article
  • Open Access
4 Citations
2,659 Views
15 Pages

Numerical Simulation of Hydrogen–Coal Blending Combustion in a 660 MW Tangential Boiler

  • Lijiang Dong,
  • Shangwen Huang,
  • Baiyun Qian,
  • Kaike Wang,
  • Ning Gao,
  • Xiang Lin,
  • Zeqi Shi and
  • Hao Lu

19 February 2024

With the adjustment of energy structure, the utilization of hydrogen energy has been widely attended. China’s carbon neutrality targets make it urgent to change traditional coal-fired power generation. The paper investigates the combustion of p...

  • Article
  • Open Access
1 Citations
1,450 Views
26 Pages

18 February 2024

Damage localization in GFRP (glass-fiber-reinforced polymer) composite plates is a crucial research area in marine engineering. This study introduces a feedback-based damage index (DI) combined with multi-label classification to enhance the accuracy...

of 19

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Processes - ISSN 2227-9717