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Antioxidants, Volume 6, Issue 3

September 2017 - 29 articles

Cover Story: Pulmonary hypertension has long been associated with the increased production of reactive oxygen and nitrogen species (ROS, RNS). The mechanisms leading to the overproduction of ROS and RNS, and how they influence pathological vascular remodeling remain topics of intense investigation. Herein, we summarize past and recent discoveries into the roles of the NADPH oxidases and nitric oxidase synthases in pulmonary hypertension and how they work individually and collectively to influence pulmonary endothelial and smooth muscle cell behavior. View this paper
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Articles (29)

  • Communication
  • Open Access
5 Citations
4,887 Views
6 Pages

20 September 2017

The aim of the current study was to determine the profile and content of polyphenols present in Erica cinerea, an important plant species from Northern Portuguese flora and often reported as having anti-inflammatory, antioxidant, and anti-radical act...

  • Review
  • Open Access
396 Citations
40,999 Views
18 Pages

Antioxidant Activity of Spices and Their Impact on Human Health: A Review

  • Alexander Yashin,
  • Yakov Yashin,
  • Xiaoyan Xia and
  • Boris Nemzer

15 September 2017

Antioxidants are substances that prevent oxidation of other compounds or neutralize free radicals. Spices and herbs are rich sources of antioxidants. They have been used in food and beverages to enhance flavor, aroma and color. Due to their excellent...

  • Review
  • Open Access
153 Citations
22,674 Views
11 Pages

15 September 2017

Grapes are one of the most widely grown fruits and have been used for winemaking since the ancient Greek and Roman civilizations. Grape seeds are rich in proanthocyanidins which have been shown to possess potent free radical scavenging activity. Grap...

  • Article
  • Open Access
3 Citations
5,455 Views
9 Pages

A Possible Indicator of Oxidative Damage in Smokers: (13Z)-Lycopene?

  • Daniel L. Graham,
  • Mario Lorenz,
  • Andrew J. Young and
  • Gordon M. Lowe

13 September 2017

In vitro, the gaseous phase of cigarette smoke is known to induce both isomerization and degradation of dietary carotenoids, such as β-carotene and lycopene. However, the effects of cigarette smoke on the composition of circulating lycopene in vivo a...

  • Article
  • Open Access
13 Citations
7,303 Views
6 Pages

A simple method for the determination of caffeine in coffee grains by GC-FID (Gas Chromatography-Flame Ionisation Detector) is presented in the current work. The method was fully validated according to ISO (International Organization for Standardizat...

  • Article
  • Open Access
39 Citations
9,859 Views
10 Pages

Solanum trilobatum L. (Solanaceae) has been well known as nightshade, commonly used by diverse populations to heal several disorders. Earlier studies in Solanum trilobatum were focused on different pharmacological activities and a few were concerned...

  • Review
  • Open Access
26 Citations
9,888 Views
14 Pages

Superoxide Dismutases in Pancreatic Cancer

  • Justin G. Wilkes,
  • Matthew S. Alexander and
  • Joseph J. Cullen

The incidence of pancreatic cancer is increasing as the population ages but treatment advancements continue to lag far behind. The majority of pancreatic cancer patients have a K-ras oncogene mutation causing a shift in the redox state of the cell, f...

  • Review
  • Open Access
158 Citations
14,969 Views
35 Pages

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that regulates hundreds of antioxidant genes, and is activated in response to oxidative stress. Given that many neurodegenerative diseases including Alzheimer’s disease, Par...

  • Article
  • Open Access
41 Citations
9,302 Views
9 Pages

Portulaca oleracea is a wild plant pest of orchards and gardens, but is also an edible vegetable rich in beneficial nutrients. It possesses many antioxidant properties due to the high content of vitamins, minerals, omega-3 essential fatty acids and o...

  • Review
  • Open Access
52 Citations
8,963 Views
21 Pages

The Ability of Exercise-Associated Oxidative Stress to Trigger Redox-Sensitive Signalling Responses

  • Richard Webb,
  • Michael G. Hughes,
  • Andrew W. Thomas and
  • Keith Morris

In this review, we discuss exercise as an oxidative stressor, and elucidate the mechanisms and downstream consequences of exercise-induced oxidative stress. Reactive oxygen species (ROS) are generated in the mitochondria of contracting skeletal myocy...

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Antioxidants - ISSN 2076-3921