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Phytochemical Constituents, Health Benefits, and Industrial Applications of Grape Seeds: A Mini-Review

Department of Public Health, Xi’an Jiaotong-Liverpool University, Suzhou 215123, China
Department of Food Science, University of Otago, Dunedin 9054, New Zealand
Authors to whom correspondence should be addressed.
Antioxidants 2017, 6(3), 71;
Received: 10 August 2017 / Revised: 9 September 2017 / Accepted: 12 September 2017 / Published: 15 September 2017
(This article belongs to the Special Issue Dietary Antioxidants and Prevention of Non-Communicable Diseases)
Grapes are one of the most widely grown fruits and have been used for winemaking since the ancient Greek and Roman civilizations. Grape seeds are rich in proanthocyanidins which have been shown to possess potent free radical scavenging activity. Grape seeds are a complex matrix containing 40% fiber, 16% oil, 11% proteins, and 7% complex phenols such as tannins. Grape seeds are rich sources of flavonoids and contain monomers, dimers, trimers, oligomers, and polymers. The monomeric compounds includes (+)-catechins, (−)-epicatechin, and (−)-epicatechin-3-O-gallate. Studies have reported that grape seeds exhibit a broad spectrum of pharmacological properties against oxidative stress. Their potential health benefits include protection against oxidative damage, and anti-diabetic, anti-cholesterol, and anti-platelet functions. Recognition of such health benefits of proanthocyanidins has led to the use of grape seeds as a dietary supplement by the consumers. This paper summarizes the studies of the phytochemical compounds, pharmacological properties, and industrial applications of grape seeds. View Full-Text
Keywords: grape seeds; grapes; proanthocyanidins; flavonoids; catechins grape seeds; grapes; proanthocyanidins; flavonoids; catechins
MDPI and ACS Style

Ma, Z.F.; Zhang, H. Phytochemical Constituents, Health Benefits, and Industrial Applications of Grape Seeds: A Mini-Review. Antioxidants 2017, 6, 71.

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