Skip to Content

Brain Sciences, Volume 16, Issue 10

2026 October - 139 articles

Cover Story: What can the skin reveal about brain health? This review traces the journey of neurological biomarkers from the brain through cerebrospinal fluid and blood to dermal interstitial fluid. It examines how compartment biology, fluid transport, and biomarker kinetics shape measurements, alongside emerging microneedle technologies for minimally invasive sampling and sensing. By distinguishing established evidence from early feasibility studies, the review highlights both the promise of skin-based monitoring and the validation needed before it can reliably support neurological assessment. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (139)

  • Article
  • Open Access
215 Views
20 Pages

21 October 2026

Background/Objectives: Video gaming places repeated demands on rapid visual information processing, response selection, and visuomotor coordination. However, it remains unclear whether current gaming in adolescence is associated with broadly enhanced...

(This article belongs to the Special Issue Advances in Multisensory Integration and Neuromotor Control)
  • Review
  • Open Access
300 Views
25 Pages

A Comprehensive Narrative Review on Autonomic Nervous System Pathophysiology in Spinal Cord Injury and the Use of Invasive and Non-Invasive Electrical Stimulation for Recovery

  • Karina Yazmín Sánchez-Lastra,
  • Rossy Attie-Harari,
  • María Fernanda Castillo-Cuadros,
  • Carlos A. Cuellar and
  • Adriana Cristina Pliego-Carrillo

21 October 2026

Spinal cord injury (SCI) significantly reduces both quality of life and life expectancy due to the loss of motor and sensory function, as well as its impact on autonomic dysfunction (AD). Complications related to AD include impaired sphincter control...

(This article belongs to the Special Issue Brain Plasticity in Health and Disease: From Molecules to Circuits)
  • Article
  • Open Access
211 Views
22 Pages

Auditory Stimulation-Evoked Frontoparietal Theta Asymmetry for Subtype Classification and Long-Term Prognosis Prediction in Disorders of Consciousness

  • Chen Chen,
  • Yajuan Hu,
  • Sifan Wang,
  • Xintong Zhang and ,
  • Shuang Zheng,
  • Jinying Han and
  • Kai Wang
  • + 2 authors+ 0 author

21 October 2026

Background: Quantitative electroencephalography (qEEG) facilitates the objective assessment of residual brain function in patients with disorders of consciousness (DOC), which addresses the intrinsic limitations of behavioral assessment methods. Neve...

(This article belongs to the Section Cognitive, Social and Affective Neuroscience)
  • Article
  • Open Access
242 Views
24 Pages

Instrumental Activities of Daily Living as a Mediator Between Cognition and Anti-Saccade Uncorrected Error Rate in CSVD: An Exploratory Analysis with Education Moderation Testing

  • Xuan Xu,
  • Kaige Zhang,
  • Luxuan Xia,
  • Xiaoxu Liu and ,
  • Liye Wang,
  • Yilan Zheng,
  • Chengru Jia,
  • Nannan Li and
  • Zhigang Chen
  • + 4 authors+ 0 author

21 October 2026

Background: Cerebral small vessel disease (CSVD) is one of the major causes of cognitive impairment and functional decline in older adults. Instrumental activities of daily living (IADL) may serve as a bridge between cognitive impairment and more bas...

(This article belongs to the Section Cognitive, Social and Affective Neuroscience)
  • Article
  • Open Access
239 Views
15 Pages

Intraoperative Measurement of Internal Carotid Artery Blood Flow Using Transit-Time Flowmetry After Carotid Endarterectomy: Results from 196 Consecutive Cases

  • Meltem Gönel,
  • Corinne Inauen,
  • Philip Heesen,
  • Martina Sebök and ,
  • Shreyes Paruvacattu,
  • Tristan Schmidlechner,
  • Elisa Colombo,
  • Veronica Percuoco,
  • Jorn Fierstra and
  • Giuseppe Esposito
  • + 9 authors+ 4 authors

21 October 2026

Background/Objectives: Carotid endarterectomy (CEA) is a standard surgical treatment for high-grade symptomatic and asymptomatic internal carotid artery (ICA) stenosis. The Transit Time Flowmeter (TTF) provides an easy-to-use tool to quantify intraop...

(This article belongs to the Section Neurosurgery and Neuroanatomy)
  • Article
  • Open Access
263 Views
16 Pages

20 October 2026

Background/Objectives: This study aimed to compare oral citicoline 500 mg/homotaurine 50 mg/nicotinamide 54 mg/pyrroloquinoline quinone 5 mg (CIT/HOMO/B3/PQQ) with citicoline 500 mg alone (CIT500) for contrast sensitivity (CS), vision-related quality...

(This article belongs to the Section Neurodegenerative Diseases)
  • Article
  • Open Access
138 Views
17 Pages

20 October 2026

Background: Chronic psychological stress can alter hypothalamic–pituitary–adrenal (HPA) axis activity and inflammatory signaling. However, the biological correlates of specific stress-related emotional experiences and expression patterns...

(This article belongs to the Section Neuropsychiatry)
  • Article
  • Open Access
155 Views
15 Pages

20 October 2026

Objective: Chronic neuroinflammation is a recognized driver of Parkinson’s disease (PD) pathophysiology, in which systemic inflammation may also participate. This study evaluated composite inflammatory indices in peripheral blood and investigat...

(This article belongs to the Section Neurodegenerative Diseases)
  • Article
  • Open Access
201 Views
20 Pages

20 October 2026

Background: The endoscopic endonasal approach (EEA) has been widely applied in the surgical treatment of skull base tumors. However, poor pneumatization of the skull base—such as inadequate sphenoid sinus pneumatization and dense clival bone&md...

(This article belongs to the Section Neurosurgery and Neuroanatomy)
  • Article
  • Open Access
1,066 Views
18 Pages

20 October 2026

Ayres Sensory Integration® (ASI) remains one of the most widely used and debated intervention approaches in occupational therapy and related disciplines. Recent advances in rehabilitation treatment specification and reporting frameworks, includin...

(This article belongs to the Special Issue Expanding the Foundation of Evidence-Based Practice in Sensory Integration)
  • Systematic Review
  • Open Access
214 Views
18 Pages

20 October 2026

Background/Objectives: Subjective cognitive decline (SCD) has been proposed as an early symptomatic manifestation of dementia/Alzheimer’s disease. However, its associated brain patterns are not yet fully characterized. In recent years, function...

(This article belongs to the Section Neuropsychology)
  • Retraction
  • Open Access
239 Views
2 Pages

RETRACTED: Akter et al. Improved Transfer-Learning-Based Facial Recognition Framework to Detect Autistic Children at an Early Stage. Brain Sci. 2021, 11, 734

  • Tania Akter,
  • Mohammad Hanif Ali,
  • Md. Imran Khan,
  • Md. Shahriare Satu and ,
  • Md. Jamal Uddin,
  • Salem A. Alyami,
  • Sarwar Ali,
  • AKM Azad and
  • Mohammad Ali Moni
  • + 4 authors+ 0 author

20 October 2026

The journal retracts the article, “Improved Transfer-Learning-Based Facial Recognition Framework to Detect Autistic Children at an Early Stage” [...]

  • Systematic Review
  • Open Access
275 Views
35 Pages

19 October 2026

Background/Objectives: The optimal cervical carotid strategy during thrombectomy for anterior-circulation tandem occlusion remains uncertain. We compared emergent carotid stenting, balloon angioplasty alone, and no targeted acute cervical revasculari...

(This article belongs to the Section Neurosurgery and Neuroanatomy)
  • Retraction
  • Open Access
244 Views
1 Page

19 October 2026

The journal retracts the article “Identification of Autism in Children Using Static Facial Features and Deep Neural Networks” [...]

  • Article
  • Open Access
256 Views
22 Pages

EEG Features of Cortical Intent for Urination and Defecation in Healthy Aging and Spinal Cord Injury: A Descriptive Feasibility Study for BCI Neurorehabilitation

  • Chuan Xue,
  • Xiangrui Cai,
  • Ziqi Guo,
  • Haoran Xu and ,
  • Jiale Xie,
  • Rui Ji,
  • Lei Cao and
  • Jie Jia
  • + 3 authors+ 0 author

18 October 2026

Background/Objectives: Systematically elucidating the neural mechanisms of bowel and bladder control is crucial for developing closed-loop brain–computer interface (BCI) neurorehabilitation for patients with spinal cord injury (SCI). This study...

(This article belongs to the Section Neurorehabilitation)
  • Article
  • Open Access
210 Views
17 Pages

Reliability and Validity of a Gamified Cognitive Assessment for Adults at High Risk of Stroke

  • Huihong Ke,
  • Wansi Zhong,
  • Xiao Zhu,
  • Rui Xue and ,
  • Yiting Ge,
  • Ying Zhou,
  • Yi Chen and
  • Min Lou
  • + 3 authors+ 0 author

18 October 2026

Background: Most existing digital cognitive assessment tools are simple adaptations of paper-and-pencil tests, lacking adequate validation in older adults and showing poor sensitivity to domain-specific deficits common in high vascular risk populatio...

(This article belongs to the Section Cognitive, Social and Affective Neuroscience)
  • Article
  • Open Access
242 Views
23 Pages

17 October 2026

Background: Electroencephalogram (EEG) signals provide important information for brain–computer interfaces (BCIs) and the diagnosis of neurological disorders but are susceptible to electrooculographic (EOG) artifacts. Traditional methods often...

(This article belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)
  • Article
  • Open Access
293 Views
20 Pages

Tractometric: A Diffusion Tractography Software Engine for Integration into a Neuronavigation System: Technical Development and Preliminary Clinical Feasibility

  • William Mendez,
  • Alejandra Bohórquez,
  • Ximena Bohórquez,
  • Oscar Bohórquez and ,
  • William J. Shelton and
  • Edgar G. Ordóñez-Rubiano
  • + 1 author+ 0 author

17 October 2026

Background: Diffusion MRI tractography can support patient-specific neurosurgical planning, but implementation may be limited by workflow complexity, software requirements, and resource constraints. We describe Tractometric®, a diffusion tractogr...

(This article belongs to the Special Issue New Trends and Technologies in Modern Neurosurgery: 2nd Edition)
  • Article
  • Open Access
234 Views
15 Pages

17 October 2026

Background/Objectives: Obsessive–compulsive disorder (OCD) severely impacts both patients and their families. This study aimed to compare sleep quality, insomnia severity, and daytime sleepiness in partners of individuals with OCD against a hea...

(This article belongs to the Special Issue Behavioural, Emotional and Cognitive Processes Linked to Healthy Sleep and Insomnia)
  • Review
  • Open Access
208 Views
25 Pages

16 October 2026

Background/Objectives: Trigeminal neuralgia (TN) disproportionately affects older adults, in whom medication intolerance, drug interactions, comorbidities, and limited physiological reserve may complicate management. This structured narrative review...

(This article belongs to the Section Neurosurgery and Neuroanatomy)
  • Article
  • Open Access
363 Views
44 Pages

16 October 2026

Background: ALS is characterized by motor neuron failure with potential neurocognitive comorbidity. Cortical neurons, and their support cells, exhibit pathologic features, some of which have been identified in post-mortem transcriptome studies of the...

(This article belongs to the Section Neurodegenerative Diseases)
  • Correction
  • Open Access
133 Views
1 Page

Correction: Yi et al. Time Overestimation Devalues Future Rewards: Electroencephalogram Evidence from Intertemporal Choice. Brain Sci. 2026, 16, 271

  • Liangliang Yi,
  • Yutong Liu,
  • Haibo Zhou,
  • Chun Lin and ,
  • Yaru Yang,
  • Xinxin Xiang,
  • Huiyingzi Li,
  • Manling Huang and
  • Xinling Wang
  • + 4 authors+ 0 author

16 October 2026

In the original publication [...]

(This article belongs to the Section Behavioral Neuroscience)
  • Review
  • Open Access
398 Views
23 Pages

16 October 2026

Background/Objectives: Prostaglandin E2 (PGE2) is a known inflammatory mediator. It is produced by cyclooxygenase (COX)-1/2 during inflammation via four distinct G protein-coupled receptors (EP1–EP4). PGE2 is involved in the development of brai...

(This article belongs to the Special Issue New Approaches to Prevent Neuropsychiatric Disorders Through the Control of Neuroinflammation)
  • Article
  • Open Access
161 Views
36 Pages

16 October 2026

Background/Objectives: Individual spikes are difficult to track through recurrent cortical circuits, where convergence, divergence, and nonlinear dynamics rapidly transform activity. However, the statistical properties of an input may remain detectab...

(This article belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)
  • Article
  • Open Access
223 Views
19 Pages

16 October 2026

Background and Objectives: Elevated intracranial pressure (ICP) is common to many encephalopathies, but the evolution of quantitative electroencephalography (qEEG) indices along a pressure gradient—and their relative suitability for early warni...

(This article belongs to the Section Neurotechnology and Neuroimaging)
  • Article
  • Open Access
158 Views
14 Pages

The Effect of Different Auditory Conditions on Pattern-Reversal Visual Evoked Potentials (PVEPs) in Healthy Adults

  • Kholoud Ahmad Bokhary,
  • Weaam Abdullah Alrashed,
  • Fahad Ali Algahtani,
  • Mansour Mohammad Almufarrej and ,
  • Murad Omar Almomani,
  • Hala Khalid Jamous,
  • Abdulrahman Faisal Albloushi and
  • Hanan Khalid Mofty
  • + 3 authors+ 0 author

15 October 2026

Background/Objectives: The aim of this study was to investigate the effect of different auditory conditions on pattern-reversal visual evoked potential (PVEP) responses among healthy adults. Methods: This repeated-measure design with a fixed baseline...

(This article belongs to the Section Sensory and Motor Neuroscience)
  • Article
  • Open Access
180 Views
13 Pages

Exercise Dependence Psychopathology Is Associated with Differential Biochemical Correlates at Admission in Anorexia Nervosa: An Exploratory Cross-Sectional Study

  • Francesco Monaco,
  • Annarita Vignapiano,
  • Ernesta Panarello,
  • Stefania Landi and ,
  • Felice Spista,
  • Rossella Bonifacio,
  • Daniela Falchetta,
  • Alessandra Marenna,
  • Maria Laura Mignone and
  • Giulio Corrivetti
  • + 7 authors+ 2 authors

15 October 2026

Background: We investigated, in an exploratory cross-sectional design, whether EDS-R score at admission showed adjusted cross-sectional associations with FT3, LDH, and ALT in patients with anorexia nervosa (AN) in residential treatment. Methods: A to...

(This article belongs to the Section Neuropsychiatry)
  • Article
  • Open Access
212 Views
20 Pages

Intentional Versus Incidental Encoding of Emotional and Navigational Memory: Preliminary Data in Healthy Young Adults

  • Andrea Di Piero,
  • Alessia Bonavita,
  • Laura Piccardi,
  • Maria Casagrande and
  • Cecilia Guariglia

15 October 2026

Background/Objectives: episodic memory refers to the ability to place events within a specific spatial and temporal context, making its association with navigation unsurprising. Incidental episodic memory involves encoding and retrieving information...

(This article belongs to the Section Neuropsychology)
  • Article
  • Open Access
229 Views
18 Pages

Accuracy of Video Optical See-Through Augmented Reality Surgical System (VOSTARS) to Guide Craniotomy: A Phantom and a Human Cadaver Study

  • Nicola Montemurro,
  • Marina Carbone,
  • Rosanna Maria Viglialoro,
  • Francesco Simi and ,
  • Giulia Zari,
  • Sara Condino and
  • Francesco Acerbi
  • + 2 authors+ 0 author

15 October 2026

Background: Augmented reality (AR) may support neuronavigation by displaying patient-specific anatomical information and surgical plans directly within the surgeon’s view of the operative field. Reliable registration between virtual content and...

(This article belongs to the Special Issue Next-Generation Tools in Neurosurgery: Robotics, Imaging and Beyond)
  • Article
  • Open Access
272 Views
35 Pages

Homeostatic and Hedonic Signals Differentially Regulate cFos Activation in PVN MC4R, PVN pro-TRH, PBN vGlut2, and PBN CRF Neuronal Populations

  • Estefania Espitia-Bautista,
  • Cinthia García-Luna,
  • Paulina Soberanes-Chávez,
  • Javier Berjón and ,
  • Elena Álvarez-Salas and
  • Patricia de Gortari
  • + 1 author+ 0 author

15 October 2026

Background: The high worldwide prevalence of obesity, with palatable food hyperphagia as its main etiological factor, justifies studying neural circuit alterations under conditions such as chronic stress and exposure to high-energy diets, which eleva...

(This article belongs to the Special Issue Neural Control of Feeding Behavior: Focus on Emotional–Metabolic Comorbidity)
  • Article
  • Open Access
290 Views
12 Pages

Long-Term Treatment Retention of Levetiracetam Monotherapy in Adults with Epilepsy: A 10-Year Retrospective Cohort Study Using Time-to-Treatment-Failure Analysis

  • Waad Hasan Alkathiri,
  • Saeed Ali Alqahtani,
  • Abdlatif Ahmed Alghaiheb,
  • Bandar Nasser Aljafen and
  • Bander Balkhi

15 October 2026

Background: This study aimed to estimate treatment retention rates for levetiracetam monotherapy in patients with epilepsy and to characterize treatment failure in this population. Methods: A retrospective cohort study included 769 adult patients wit...

(This article belongs to the Section Neuropharmacology and Neuropathology)
  • Article
  • Open Access
330 Views
16 Pages

Analysis of Selected Cognitive Abilities and Temperamental Traits Among Young Adults Playing Video Games

  • Justyna Krzepota,
  • Krzysztof Wrześniewski,
  • Joanna Basiaga-Pasternak,
  • Marek Cieśluk and ,
  • Aneta Łuć,
  • Tomasz Sacewicz and
  • Dorota Sadowska
  • + 2 authors+ 0 author

14 October 2026

Objectives: The aim of this study was to analyse cognitive functioning and temperamental traits among young adults differing in their level of engagement in video gaming. Methods: The analysis included 67 male students from the Józef Piłs...

(This article belongs to the Special Issue Advances in Assessment and Training of Perceptual-Motor Performance (2nd Edition))
  • Article
  • Open Access
270 Views
34 Pages

14 October 2026

Background: Automatic sleep staging is fundamental to sleep architecture analysis and the diagnosis of sleep disorders. Sleep staging requires jointly modeling complementary information across modalities, multi-scale physiological features, and tempo...

(This article belongs to the Section Sleep and Circadian Neuroscience)
  • Systematic Review
  • Open Access
574 Views
22 Pages

Neglected Posterior Cervical Myelomeningocele in Adults: Systematic Review of the Literature and Illustrative Case

  • Adi Ahmetspahic,
  • Razim Mahmutagic,
  • Bekir Rovcanin,
  • Ibrahim Omerhodzic and ,
  • Edina Dozic,
  • Deniz Bulja,
  • Mirza Pojskic and
  • Kenan I. Arnautović
  • + 3 authors+ 0 author

14 October 2026

Objectives: Adult posterior cervical spinal dysraphism, including meningocele (MC), myelomeningocele (MMC), and myelocystocele (MyCC) is exceptionally rare and remains insufficiently characterised. This study aimed to conduct the first systematic rev...

(This article belongs to the Section Neurosurgery and Neuroanatomy)
  • Perspective
  • Open Access
676 Views
38 Pages

14 October 2026

Objectives: Developmental dyslexia is a heterogeneous neurodevelopmental condition in which motor, perceptual, attentional, respiratory, and sleep-related differences have been reported alongside reading difficulties. This Perspective proposes a prop...

(This article belongs to the Section Sensory and Motor Neuroscience)
  • Article
  • Open Access
649 Views
19 Pages

14 October 2026

Background/Objectives: To address the needs of mothers of children with sensory integration differences, we need a greater understanding of their experience and what they find helpful. This study aimed to explore the impact of child sensory integrati...

(This article belongs to the Special Issue Expanding the Foundation of Evidence-Based Practice in Sensory Integration)
  • Hypothesis
  • Open Access
223 Views
18 Pages

14 October 2026

A quarter-century of neuroaesthetics and cultural epidemiology has established that engagement with art is broadly and durably health-bearing, yet the finding sits awkwardly within the paradigm through which it is usually read: a tacit exposure model...

(This article belongs to the Special Issue Art Meets Neuroscience)
  • Systematic Review
  • Open Access
234 Views
31 Pages

Cognitive Impairment in Drug-Resistant Epilepsy: A Multidomain Systematic Review

  • Mateusz Bargielski,
  • Edyta Adamska-Patruno,
  • Adam Krętowski,
  • Jan Kochanowicz and ,
  • Alina Kułakowska and
  • Monika Chorąży
  • + 1 author+ 0 author

13 October 2026

Background: Drug-resistant epilepsy (DRE) is frequently accompanied by cognitive impairment across multiple neuropsychological domains. Objectives: We aimed to synthesize contemporary evidence on cognitive impairment, neurobiological correlates, pote...

(This article belongs to the Section Neuropsychology)
  • Article
  • Open Access
357 Views
16 Pages

Twins Discordant for Parkinson’s Disease: A 10-Year Longitudinal Follow-Up of Mortality, Clinical and Lifestyle Features, Nutritional Status, and Dietary Habits

  • Michela Barichella,
  • Antonio Natale,
  • Elena Contaldi,
  • Luca Magistrelli and ,
  • Emanuele Cereda,
  • Carlotta Bolliri,
  • Maria Carmela Macchione,
  • Federica Invernizzi,
  • Daniela Calandrella and
  • Gianni Pezzoli
  • + 6 authors+ 1 author

13 October 2026

Background/Objectives: Twins discordant for Parkinson’s disease (PD) share genetic background and early-life exposures, offering a model for non-genetic determinants of disease. We aimed to evaluate longitudinally the mortality, clinical and li...

(This article belongs to the Special Issue New Approaches in the Exploration of Parkinson’s Disease: 2nd Edition)
  • Article
  • Open Access
230 Views
17 Pages

13 October 2026

Background/Objectives: Third-ventricle colloid cysts are benign but can cause obstructive hydrocephalus and sudden deterioration, and the role of microsurgical transcallosal resection in the endoscopic era remains debated. We evaluated clinical, radi...

(This article belongs to the Topic Innovations in Brain Tumor Surgery: Techniques and Outcomes)
  • Article
  • Open Access
274 Views
12 Pages

12 October 2026

Background: Immune dysregulation has been implicated in the pathophysiology of autism spectrum disorder (ASD). Soluble urokinase plasminogen activator receptor (suPAR) is a stable biomarker of chronic immune activation that has not previously been in...

(This article belongs to the Special Issue Biomarker Development in the Early Identification of Autism Spectrum Disorders)
  • Article
  • Open Access
196 Views
14 Pages

12 October 2026

Background: Chronic subdural hematoma (CSDH) is the most common bleeding disorder in the nervous system and has a high recurrence rate, posing a serious threat to the lives of elderly individuals. Early identification and adjustment of the treatment...

(This article belongs to the Section Neurosurgery and Neuroanatomy)
  • Article
  • Open Access
315 Views
20 Pages

MPTP-Induced D1R-Dependent Dysregulation of Ventral Hippocampal Newborn Cell Pools and Associated Alterations in the Hypothalamic–Pituitary–Adrenal Axis

  • Tingting Di,
  • Kai Zhang,
  • Qian Ru,
  • Wenxuan Yin and ,
  • Yilin Jin,
  • Ling Chen and
  • Hualing Li
  • + 2 authors+ 0 author

12 October 2026

Objective: This study investigated how dopaminergic (DAergic) depletion-induced ventral hippocampal neurogenesis triggers hypothalamic–pituitary–adrenal (HPA) axis hyperactivity. Methods: Three-month-old male C57BL/6 mice were subjected t...

  • Review
  • Open Access
544 Views
18 Pages

12 October 2026

With the accelerating process of global aging, Alzheimer’s disease (AD) has become an enormous public health burden worldwide. However, its pathogenesis is still not fully understood beyond the classic amyloid-β (Aβ) and tau hypothese...

(This article belongs to the Section Neurodegenerative Diseases)
  • Editorial
  • Open Access
224 Views
5 Pages

12 October 2026

Mental disorders among children, adolescents, and young adults represent a major and growing public health concern [...]

(This article belongs to the Special Issue Emerging Trends in Youth Mental Health)
  • Article
  • Open Access
219 Views
17 Pages

10 October 2026

Background/Objectives: Patients with acute ischemic stroke (AIS) and coexisting malignancy have worse outcomes, but it is unclear how much of this reflects malignancy itself rather than pre-stroke function, stroke severity and systemic inflammation....

(This article belongs to the Section Neuro-oncology)
  • Article
  • Open Access
232 Views
17 Pages

Head-Mounted Augmented Reality in the Planning of Cerebral Cavernous Malformation Resections: Demonstrating Feasibility Through an Initial Case Series

  • Luke L. Jouppi,
  • Clifford A. Pierre,
  • Matias Luis Costa,
  • Radwan I. Takroni and ,
  • Nicholas Caffes,
  • Stepan Capek,
  • Aaron J. Gustin,
  • Majid Aljoghaiman,
  • Zane A. Tymchak and
  • Stephen J. Monteith
  • + 6 authors+ 1 author

10 October 2026

Objectives: Lesion localization, associated vascular structures, and corticotomy selection pose key challenges when planning cerebral cavernous malformation (CCM) resections in eloquent areas. Head-mounted augmented reality (HMAR) may improve visuali...

(This article belongs to the Special Issue Advancing Cerebrovascular Care: From Translational Innovation to Patient-Centered Outcomes)
  • Systematic Review
  • Open Access
375 Views
28 Pages

Glial Contributions to Pain in Neurodegenerative Disease Models: A Systematic Review of Microglial and Astrocytic Evidence

  • Alfonso Alfaro-Rodríguez,
  • José Luis Cortes-Altamirano,
  • Samuel Reyes-Long,
  • Herlinda Bonilla-Jaime and ,
  • Francisco Jacob Avila-Camacho,
  • Leonardo Miguel Moreno-Villalba,
  • María Elizabeth Herrera-López,
  • Angelica González-Maciel,
  • Beatríz Pérez-Guille and
  • Hugo Juaréz-Olguín
  • + 7 authors+ 2 authors

10 October 2026

Background/Objectives: Pain is a common and disabling non-motor manifestation of neurodegenerative disorders, but the contribution of glial cells to nociceptive processing remains incompletely understood. This systematic review evaluated evidence fro...

(This article belongs to the Special Issue The Interplay Between the Brain, Behavior and Immunity)
  • Review
  • Open Access
371 Views
25 Pages

Post-Stroke Olfactory Dysfunction: Network Mechanisms, Clinical Consequences, and Rehabilitation

  • Thomas Heinbockel,
  • Gursimran Virdi,
  • Lexington Shannon and
  • Sayan Nandi

10 October 2026

Stroke is the second leading cause of death after ischemic heart disease, accounting for 10% of all deaths worldwide. Stroke is also a major cause of long-term neurological disability, yet olfactory dysfunction remains an underrecognized consequence...

(This article belongs to the Special Issue Advanced Study in Stroke and Stroke Rehabilitation)
  • Article
  • Open Access
205 Views
16 Pages

10 October 2026

Background: Acute kidney injury (AKI) requiring renal replacement therapy (RRT) is common in critically ill patients and is frequently accompanied by delirium. Intradialytic hemodynamic instability, particularly hypotension, may impair cerebral perfu...

(This article belongs to the Special Issue Psychological Disorders in Mechanically Ventilated Critical Care Patients: Novel Tools for Diagnosis and Treatment)

of 3

XFacebookLinkedIn
Brain Sci. - ISSN 2076-3425