Neural Control of Feeding Behavior: Focus on Emotional–Metabolic Comorbidity
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Behavioral Neuroscience".
Deadline for manuscript submissions: 30 October 2026 | Viewed by 2
Special Issue Editors
Interests: neurobiology of feeding; mood disorders; stress; neuropsychiatry; neuroendocri-nology; TRH; CRH
Special Issue Information
Dear Colleagues,
Mood and affective disorders are neuropsychiatric illnesses involving aberrant adaptations in different brain circuits that may induce uncoordinated feeding behavior due to energy homeostasis deviations, as well as impaired emotional response to diverse environmental stimuli. Thus, a high prevalence of comorbidities is reported worldwide between hyperphagia and obesity, polycystic ovarian syndrome, and hypothyroidism, as well as between anorexia and malnourishment and anxiety, depression, and impulsive symptoms. However, we are a long way from understanding the specific roles of neuropeptide and neurotransmitter pathways in homeostatic and hedonic feeding regulation, along with their induction of associated anxiety or depression-like behaviors. This Special Issue will share updates on the identification of cellular and receptor types, neurotransmitter pathways, and intracellular pathways targeted by different feeding-regulating neuropeptides that affect food intake or emotional response. We also welcome submissions exploring the specific neural mechanisms and circuits involved in responses to diverse environmental stimuli that induce either mood or feeding disturbances, as well as afferent and efferent connections between homeostatic and hedonic feeding-regulatory neural substrates and peripheral tissues that affect metabolic pathways and contribute to the development of obesity and other metabolic disorders. We encourage studies aiming to elucidate the effects of hypothalamic circadian clock gene products that control metabolic pathway rhythms between day and night in the peripheral tissues, where lipogenesis and lipolysis are essential.
Dr. Patricia de Gortari
Dr. Cinthia García-Luna
Guest Editors
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Keywords
- feeding
- mood disorders
- anxiety
- depression
- obesity
- anorexia
- schizophrenia
- neuropeptides
- hypothalamus
- amygdala
- nucleus accumbens
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