New Approaches to Prevent Neuropsychiatric Disorders Through the Control of Neuroinflammation
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurodegenerative Diseases".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 21
Special Issue Editor
Special Issue Information
Dear Colleagues,
In recent years, it has been suggested that neuroinflammation (for example, smoldering) is involved in the onset of neuropsychiatric disorders, including Alzheimer's disease. The involvement of M2-type microglia in the brain has also been pointed out in this smoldering inflammation. Given the limitations of neuropsychiatric disorder treatment, suppressing neuroinflammation in the brain is expected to have a neuroprotective effect. Previous drugs have worked by stimulating receptors or inhibiting enzymes. However, continuous stimulation of receptors changes how the drugs work, ultimately leading to polypharmacy. We therefore believe that good clinical effects can be achieved by acting neuroprotectively (by suppressing smoldering inflammation).
Neuropsychiatric disorders may be prevented. From the perspective of preventing neuropsychiatric disorders, proposing new countermeasures is an important research theme that can also lead to a reduction in the number of patients suffering from neuropsychiatric disorders.
This Special Issue welcomes submissions with the aim of collecting more research papers and reviews to explore the relationship between neuroinflammation and various neuropsychiatric diseases, and to achieve the prevention and treatment of neuropsychiatric diseases.
Prof. Dr. Yoshikaszu Matsuda
Guest Editor
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Keywords
- neuroinflammation
- Alzheimer's disease
- microglia
- neuroprotective effect
- neuropsychiatric disorders
- smoldering inflammation
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