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Journal of Personalized Medicine, Volume 12, Issue 10

October 2022 - 213 articles

Cover Story: Abnormal sensory reactivity in autism spectrum disorder (ASD) is associated with autism severity, poorer functional outcomes, and behavioral difficulties across the lifespan. The Sensory Processing Measure—Preschool (SPM-P) and the Child Behavior Checklist were collected from parents of preschoolers with ASD and specific developmental language disorder, as well as those of typically developing peers. The results indicate a similar SPM-P pattern for both clinical populations, with higher scores than those of the controls. And the sensory deficits predict behavioral abnormalities in ASD. The early characterization of sensory profiles in ASD has significant clinical and social implications, potentially driving the interventions for improving their social participation. View this paper
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Articles (213)

  • Article
  • Open Access
12 Citations
3,966 Views
14 Pages

21 October 2022

Background: Research on the discovery of tumor biomarkers based on big data analysis is actively being conducted. This study aimed to secure foundational data for identifying new biomarkers of breast cancer via breast cancer datasets in The Cancer Ge...

  • Review
  • Open Access
2,091 Views
12 Pages

21 October 2022

The ribosomal DNA and pericentromeric satellite repeats are two important types of moderately repeated sequences existing in the human genome. They are functionally involved in the universal stress response. There is accumulating evidence that the co...

  • Article
  • Open Access
9 Citations
2,545 Views
11 Pages

21 October 2022

We aimed to investigate treatment outcome and satisfaction with bladder outlet surgeries and bladder management in patients with spinal cord injury (SCI), voiding dysfunction, and to seek a spontaneous voiding or reflex voiding program. A total of 26...

  • Article
  • Open Access
2 Citations
2,744 Views
13 Pages

21 October 2022

MicroRNAs (miRNAs) regulate gene expression by binding to mRNAs, and thus reduce target gene expression levels and expression variability, also known as ‘noise’. Single-cell RNA sequencing (scRNA-seq) technology has been used to study miR...

  • Article
  • Open Access
4 Citations
2,334 Views
12 Pages

Investigation of Different Methods of Intraoperative Graft Perfusion Assessment during Kidney Transplantation for the Prediction of Delayed Graft Function: A Prospective Pilot Trial

  • Andreas L. H. Gerken,
  • Michael Keese,
  • Christel Weiss,
  • Hanna-Sophie Krücken,
  • Katarina A. P. Pecher,
  • Augusto Ministro,
  • Nuh N. Rahbari,
  • Christoph Reissfelder,
  • Ulrich Rother and
  • Babak Yazdani
  • + 3 authors

21 October 2022

Delayed graft function (DGF) after renal transplantation is a relevant clinical problem affecting long-term organ function. The early detection of patients at risk is crucial for postoperative monitoring and treatment algorithms. In this prospective...

  • Article
  • Open Access
4 Citations
2,466 Views
9 Pages

Entry Point Variation in the Osseous Fixation Pathway of the Anterior Column of the Pelvis—A Three-Dimensional Analysis

  • Lotte Dupuis,
  • Laura A. van Ginkel,
  • Luc M. Verhamme,
  • Thomas J. J. Maal,
  • Erik Hermans and
  • Vincent M. A. Stirler

21 October 2022

Fractures of the superior pubic ramus can be treated with screw insertion into the osseous fixation pathway (OFP) of the anterior column (AC). The entry point determines whether the screw exits the OFP prematurely. This can be harmful when it enters...

  • Article
  • Open Access
12 Citations
3,702 Views
12 Pages

Cerebrospinal Fluid Biomarker Profile in TDP-43-Related Genetic Frontotemporal Dementia

  • Elisabeth Kapaki,
  • Foteini Boufidou,
  • Mara Bourbouli,
  • Efstratios-Stylianos Pyrgelis,
  • Vasilios C. Constantinides,
  • Cleo Anastassopoulou and
  • George P. Paraskevas

21 October 2022

Cerebrospinal fluid (CSF) biomarkers, namely total tau, phospho-tau and amyloid beta peptides, have received much attention specifically regarding Alzheimer’s disease (AD), since they can detect the biochemical fingerprint of AD and serve as a...

  • Commentary
  • Open Access
14 Citations
3,794 Views
12 Pages

Integrating a Comprehensive Cancer Genome Profiling into Clinical Practice: A Blueprint in an Italian Referral Center

  • Camilla Nero,
  • Simona Duranti,
  • Flavia Giacomini,
  • Angelo Minucci,
  • Luciano Giacò,
  • Alessia Piermattei,
  • Maurizio Genuardi,
  • Tina Pasciuto,
  • Andrea Urbani and
  • Gennaro Daniele
  • + 5 authors

20 October 2022

The implementation of cancer molecular characterization in clinical practice has improved prognostic re-definition, extending the eligibility to a continuously increasing number of targeted treatments. Broad molecular profiling technologies better th...

  • Review
  • Open Access
30 Citations
5,662 Views
13 Pages

Advanced Bladder Cancer: Changing the Treatment Landscape

  • Vladimir Bilim,
  • Hiroo Kuroki,
  • Yuko Shirono,
  • Masaki Murata,
  • Kaede Hiruma and
  • Yoshihiko Tomita

20 October 2022

Bladder cancer is the 10th most common cancer type in the world. There were more than 573,000 new cases of bladder cancer in 2020. It is the 13th most common cause of cancer death with an estimated more than 212,000 deaths worldwide. Low-grade non-mu...

  • Article
  • Open Access
1 Citations
1,846 Views
10 Pages

Influence of Renal Impairment on the Success of Reconstruction Using Microvascular Grafts—A Retrospective Study of 251 Free Flaps

  • Henriette L. Moellmann,
  • Nadia Karnatz,
  • Ilkan Degirmenci,
  • Antonina Gyurova,
  • Lorenz Sellin and
  • Majeed Rana

20 October 2022

Background: In head and neck surgery, reconstruction using microvascular grafts is a successful method for functional and aesthetic restoration. Due to technological advances and medical care, the number of patients with comorbidities and diseases re...

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J. Pers. Med. - ISSN 2075-4426