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Diagnostics, Volume 7, Issue 1

March 2017 - 18 articles

Cover Story: Full-field digital mammography (FFDM) has been the gold standard for early detection of breast cancer, but if a woman has dense breast tissue, a false negative diagnosis may occur, with devastating consequences: more costly treatment and a poorer prognosis. Because ultrasound can penetrate dense fibro-glandular tissue, we have developed and tested a single imaging system that integrates both FFDM and automated breast ultrasound (ABUS) in a single platform. Our Aceso system has shown the potential of co-registered FFDM and ABUS images to detect breast cancer early in a busy clinic. View this paper
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Articles (18)

  • Article
  • Open Access
4 Citations
7,931 Views
12 Pages

Symptoms Relevant to Surveillance for Ovarian Cancer

  • Robert M. Ore,
  • Lauren Baldwin,
  • Dylan Woolum,
  • Erika Elliott,
  • Christiaan Wijers,
  • Chieh-Yu Chen,
  • Rachel W. Miller,
  • Christopher P. DeSimone,
  • Frederick R. Ueland and
  • Richard J. Kryscio
  • + 2 authors

To examine how frequently and confidently healthy women report symptoms during surveillance for ovarian cancer. A symptoms questionnaire was administered to 24,526 women over multiple visits accounting for 70,734 reports. A query of reported confiden...

  • Article
  • Open Access
5 Citations
10,166 Views
10 Pages

Detecting Breast Cancer with a Dual-Modality Device

  • Kamila Padia,
  • Tania S. Douglas,
  • Lydia L. Cairncross,
  • Roland V. Baasch and
  • Christopher L. Vaughan

Although mammography has been the gold standard for the early detection of breast cancer, if a woman has dense breast tissue, a false negative diagnosis may occur. Breast ultrasound, whether hand-held or automated, is a useful adjunct to mammography...

  • Review
  • Open Access
7 Citations
7,174 Views
11 Pages

Evaluation of costs and benefits associated with cancer screening should include consideration of any psychological and behavioral impact associated with screening participation. Research examining the psychological and behavioral impact of screening...

  • Opinion
  • Open Access
75 Citations
14,075 Views
8 Pages

The history of biomarkers and ultrasonography dates back over more than 50 years. The present status of biomarkers used in the context of ovarian cancer is addressed. Attention is given to new interpretations of the etiology of ovarian cancer. Cancer...

  • Article
  • Open Access
8 Citations
8,678 Views
11 Pages

Complications from Surgeries Related to Ovarian Cancer Screening

  • Lauren A. Baldwin,
  • Edward J. Pavlik,
  • Emma Ueland,
  • Hannah E. Brown,
  • Kelsey M. Ladd,
  • Bin Huang,
  • Christopher P. DeSimone,
  • John R. Van Nagell,
  • Frederick R. Ueland and
  • Rachel W. Miller

The aim of this study was to evaluate complications of surgical intervention for participants in the Kentucky Ovarian Cancer Screening Program and compare results to those of the Prostate, Lung, Colorectal and Ovarian Cancer Screening trial. A retros...

  • Commentary
  • Open Access
5 Citations
7,935 Views
9 Pages

The diagnosis of acute human immunodeficiency virus (HIV) infection (AHI) plays a unique role in preventing the spread of HIV and ending the epidemic. Acutely infected individuals are thought to contribute substantially to forward transmissions of HI...

  • Review
  • Open Access
89 Citations
14,665 Views
10 Pages

Subtypes of Ovarian Cancer and Ovarian Cancer Screening

  • Masafumi Koshiyama,
  • Noriomi Matsumura and
  • Ikuo Konishi

Ovarian cancer is the foremost cause of gynecological cancer death in the developed world, as it is usually diagnosed at an advanced stage. In this paper we discuss current issues, the efficacy and problems associated with ovarian cancer screening, a...

  • Article
  • Open Access
47 Citations
8,646 Views
10 Pages

A Pilot Study into the Association between Oral Health Status and Human Papillomavirus—16 Infection

  • Charles Xiaohang Sun,
  • Nigel Bennett,
  • Peter Tran,
  • Kai Dun Tang,
  • Yenkai Lim,
  • Ian Frazer,
  • Lakshman Samaranayake and
  • Chamindie Punyadeera

Background: Over the next 20 years, oropharyngeal cancers (OPC) will represent the majority of head and neck cancers (HNCs) in the United States. It is estimated that human papillomavirus (HPV) may account for as much as 70% to 80% of OPCs in North A...

  • Concept Paper
  • Open Access
43 Citations
12,466 Views
17 Pages

In this era of precision oncology, there has been an exponential growth in the armamentarium of genomically targeted therapies and immunotherapies. Evaluating early responses to precision therapy is essential for “go” versus “no go” decisions for the...

  • Article
  • Open Access
12 Citations
8,187 Views
17 Pages

Multivariate Feature Selection of Image Descriptors Data for Breast Cancer with Computer-Assisted Diagnosis

  • Carlos E. Galván-Tejada,
  • Laura A. Zanella-Calzada,
  • Jorge I. Galván-Tejada,
  • José M. Celaya-Padilla,
  • Hamurabi Gamboa-Rosales,
  • Idalia Garza-Veloz and
  • Margarita L. Martinez-Fierro

Breast cancer is an important global health problem, and the most common type of cancer among women. Late diagnosis significantly decreases the survival rate of the patient; however, using mammography for early detection has been demonstrated to be a...

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Diagnostics - ISSN 2075-4418