Table of Contents
Cells, Volume 8, Issue 4 (April 2019)
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Cover Story (view full-size image) With optimized parameters and modal image fusion, the novel imaging approach of atomic force [...] Read more. With optimized parameters and modal image fusion, the novel imaging approach of atomic force acoustic microscopy (AFAM) has been successfully used to characterize the substructures of various cells and, further, to build an atlas of nanoscale subcellular details in a nondestructive and convenient manner, which can help researchers to clarify the cell structures in diverse biological fields. This cell imaging technique has great practical significance and application prospects for exploring pathogenesis, clinical manifestations, and gene lesions due to its high resolution, rapid imaging speed, nondestructive detection nature (transmission), and easy operation. This approach could enhance the potential applications of AFAM in mapping subcellular structures at the nanoscale. View this paper