Stem Cells in Personalized Medicine
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Stem Cells".
Deadline for manuscript submissions: closed (31 March 2019) | Viewed by 110060
Special Issue Editor
Interests: stem cell; regenerative medicine; fibrosis and cascade; wound healing
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the last decade, personalized medicine has gained a lot of traction and has pushed the limits of what we can do clinically. The first generation of personalized medicine employed individual analysis of a patient’s unique biology to select more efficacious diagnostic methods and/or suggest clinical treatments. The focus was on identifying genetic factors to assist with selecting treatments, personalizing screens or diagnoses, and honing detection of potential diseases. Currently, these applications offer routine clinical services for patients. Subsequently, personalized medicine has progressed into fields such as gene therapy, cancer treatment, and surgical treatment/design. However, the true potential of personalized medicine, extending well beyond these current applications, waits to be fully realized.
Most disease, trauma, and infectious pathologies are consequences of cellular damage at differing levels. The key to the mitigating cell and/or tissue damage repair needs cell therapy. Stem cell therapy is a promising treatment that can be tailored not only to an illness but also to an individual patient. The potential of stem cell therapy includes a futuristic personalized “medication” in the event of tissue damage secondary to surgeries, toxins, trauma, aging, complications from medication, autoimmune disease, and numerous other problems limited by current medicine. Autologous cell sources are the first priority for cell therapy since they are safe, do not violate ethical perspectives and do not provoke immunogenic responses. Among the various autologous cell sources, induced pluripotent stem cells (iPSCs) show great potential for cell therapy application. In addition to directly treating patient tissue, iPSCs are also inducible into specialized disease cells for quick, easy, and personalized drug testing and dose selecting.
Personalized medicine through stem cell therapy has many benefits that are essential for the future of personal health. The current Special Issue will accept studies and reviews in all fields of personalized medicine. Stem cell-related studies on basic science and translational application in personalized medicine will be welcomed. The goal of this issue is to provide an overview of novel studies, as well as updated classical studies, in personalized medicine.
Prof. Yong Li
Guest Editor
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Keywords
- Personalized medicine
- Stem cells
- Induced pluripotent stem cells (iPSCs)
- Genetic identification
- Diagnosis
- Drug testing
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