Special Issue "Hepatitis C Virus and Host Interactions"
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: closed (28 February 2019) | Viewed by 80678
The coevolution of viruses with their hosts has resulted in important and specific interactions that affect the survival of both species. Many such crucial virus–host interactions have been identified and characterized for many viruses and their hosts, but even more remain to be revealed. The hepatitis C virus (HCV) is one such virus for which we already know of many critical virus host interactions. On the cellular level, HCV is known to interact with multiple cellular receptors in order to gain entry into host cells, and we know of numerous virus-host interactions that are at play during other steps of the HCV life cycle, including replication and virus production. Despite all that we have learned, many questions still remain regarding HCV. For example, why does a small percentage of HCV-infected individuals manage to clear the virus without any therapeutic intervention? How does the virus cause liver pathogenesis and in many cases hepatocellular carcinoma? What will happen to the immune system once the virus has been eliminated from the body? Great strides have been made toward answering these and other important questions, but clear answers will require continued examination of virus-host interactions in the context of HCV infection. The answers to these questions will help us to better understand HCV and its pathogenesis, as well as that of other viruses.
The purpose of this Special Issue is to highlight recent findings regarding how HCV interacts with its host at the cellular and organism levels. The goal of this issue is to provide a broad scope that would include research papers and reviews related to specific interactions between viral and cellular components, as well virus–host interactions, directly or indirectly affecting pathogenesis and disease.
Dr. Rod Russell
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- innate immunity
- programmed cell ceath
- viral pathogenesis