Nutrients, Volume 14, Issue 7 (April-1 2022) – 214 articles
Nausea, vomiting, and abdominal pain in diabetic patients are often attributed to gastropathy (DG).
Jejunal nutrition (JN) may improve nutrition and symptoms in difficult cases.
The J4G study tested this hypothesis. DG patients with moderate-to-severe symptoms, diabetic and healthy controls were entered into a randomized, double-blind controlled trial. JN with liquid nutrient or water (placebo) was infused prior to oral ingestion of the mixed solid/liquid “Nottingham Test Meal”.
Post-prandial symptoms were reduced after JN in DG patients. The mechanism is not primarily mediated by specific effects on GE but involved other aspects of GI function, including visceral sensitivity. View this paper
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