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Nutrients, Volume 10, Issue 4

April 2018 - 142 articles

Cover Story: Here meta-analysis and experimental data demonstrate a link between protein biosynthesis impairment and neurodegeneration such as Alzheimer’s disease (AD). Protein biosynthesis reduces at step of tRNA aminoacylation in AD patients. Inhibitors of tryptophanyl-tRNA synthetase (TrpRS), an enzyme of protein biosynthesis cause such decrease. Gut microbiome produce TrpRS inhibitors - tryptamine, tryptophanol and indoleacetic acid. Tryptamine and tryptophanol induce neurotoxicity and formation of fibrillary tangles similar to those detected in AD brain. Monoamine oxidases (MAO) degrade tryptamine into indoleacetic acid. Tryptamine presents in food. Dietary supplements and antibiotics can increase tryptamine content in stool. Tryptamine easily crosses blood-brain barrier and induces pathology in brain blood vessels. Combination of high tryptamine with MAO inhibitors prescribed as anti-depressants can be lethal. View this paper
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Articles (142)

  • Article
  • Open Access
9 Citations
4,866 Views
25 Pages

21 April 2018

The objectives of this study were to: (1) Use molecular spectroscopy as a novel technique to quantify protein molecular structures in relation to its chemical profiles and bioenergy values in oil-seeds and co-products from bio-oil processing. (2) Det...

  • Article
  • Open Access
19 Citations
5,821 Views
11 Pages

Optimal Adherence to a Mediterranean Diet and High Muscular Fitness Are Associated with a Healthier Cardiometabolic Profile in Collegiate Students

  • Robinson Ramírez-Vélez,
  • Jorge Enrique Correa-Bautista,
  • Mónica Liliana Ojeda-Pardo,
  • Carolina Sandoval-Cuellar,
  • Antonio García-Hermoso,
  • Hugo Alejandro Carrillo,
  • Katherine González-Ruíz,
  • Daniel Humberto Prieto-Benavides,
  • Alejandra Tordecilla-Sanders and
  • Arvydas Martinkėnas
  • + 1 author

20 April 2018

The aim of the study was to investigate the combined association of adherence to a Mediterranean diet (MedDiet) and muscular fitness (MF) with cardiometabolic health in collegiate students. The present cross-sectional analysis consisted of 1248 (714...

  • Review
  • Open Access
39 Citations
14,464 Views
8 Pages

20 April 2018

Chronic kidney disease and reduced glomerular filtration rate are risk factors for the development of chronic metabolic acidosis. The prevention or correction of chronic metabolic acidosis has been found to slow progression of chronic kidney disease....

  • Article
  • Open Access
41 Citations
11,214 Views
14 Pages

Iodine Deficiency in a Study Population of Norwegian Pregnant Women—Results from the Little in Norway Study (LiN)

  • Lisbeth Dahl,
  • Maria Wik Markhus,
  • Perla Vanessa Roldan Sanchez,
  • Vibeke Moe,
  • Lars Smith,
  • Helle Margrete Meltzer and
  • Marian Kjellevold

20 April 2018

Iodine sufficiency is particularly important in pregnancy, where median urinary iodine concentration (UIC) in the range of 150–250 µg/L indicates adequate iodine status. The aims of this study were to determine UIC and assess if dietary a...

  • Article
  • Open Access
33 Citations
6,002 Views
18 Pages

20 April 2018

Strychnos alkaloids (SAs) are the main toxic constituents in Semen Strychni, a traditional Chinese medicine, which is known for its fatal neurotoxicity. Hence, the present study was carried out to evaluate the neurotoxicity induced by SAs and the pre...

  • Article
  • Open Access
13 Citations
5,713 Views
15 Pages

The Mediating Role of Overweight and Obesity in the Prospective Association between Overall Dietary Quality and Healthy Aging

  • Karen E. Assmann,
  • Indunil Ruhunuhewa,
  • Moufidath Adjibade,
  • Zhen Li,
  • Raphaëlle Varraso,
  • Serge Hercberg,
  • Pilar Galan and
  • Emmanuelle Kesse-Guyot

20 April 2018

Background: Our objective was to quantify to what extent the association between adherence to the French nutritional recommendations at midlife, measured by the Programme National Nutrition Santé-Guideline Score (PNNS-GS), and healthy aging (H...

  • Article
  • Open Access
13 Citations
6,727 Views
12 Pages

19 April 2018

Acute kidney injury (AKI) is a frequent and serious condition with high mortality. The presence of hypermetabolism may be a factor related to poorer prognosis. This study evaluated the resting energy expenditure (REE) of intensive care unit (ICU) pat...

  • Article
  • Open Access
53 Citations
13,067 Views
13 Pages

Protein Intake and Distribution in Relation to Physical Functioning and Quality of Life in Community-Dwelling Elderly People: Acknowledging the Role of Physical Activity

  • Dominique S. M. Ten Haaf,
  • Ellen J. I. Van Dongen,
  • Malou A. H. Nuijten,
  • Thijs M. H. Eijsvogels,
  • Lisette C. P. G. M. De Groot and
  • Maria T. E. Hopman

19 April 2018

Increasing total protein intake and a spread protein intake distribution are potential strategies to attenuate sarcopenia related loss of physical function and quality of life. The aim of this cross-sectional study was to investigate whether protein...

  • Article
  • Open Access
17 Citations
13,553 Views
11 Pages

19 April 2018

To stimulate muscle protein synthesis, it is important to increase the plasma levels of essential amino acids (EAA), especially leucine, by ingesting proteins. Protein hydrolysate ingestion can induce postprandial hyperaminoacidemia; however, it is u...

  • Article
  • Open Access
3 Citations
6,881 Views
20 Pages

Regression Analysis to Identify Factors Associated with Household Salt Iodine Content at the Sub-National Level in Bangladesh, India, Ghana and Senegal

  • Jacky Knowles,
  • Roland Kupka,
  • Sam Dumble,
  • Greg S. Garrett,
  • Chandrakant S. Pandav,
  • Kapil Yadav,
  • Baitun Nahar,
  • Ndeye Khady Touré,
  • Esi Foriwa Amoaful and
  • Jonathan Gorstein

19 April 2018

Regression analyses of data from stratified, cluster sample, household iodine surveys in Bangladesh, India, Ghana and Senegal were conducted to identify factors associated with household access to adequately iodised salt. For all countries, in single...

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Nutrients - ISSN 2072-6643