You are currently viewing a new version of our website. To view the old version click .

Journal of Xenobiotics, Volume 15, Issue 5

October 2025 - 38 articles

Cover Story: Dendritic cells (DCs) are crucial for antiviral defence through nucleic acid sensing in endosomal compartments. In this study, we show that sub-toxic exposure to diesel exhaust particles and PM2.5 does not induce cytotoxicity; however, these particles accumulate within DCs. The reduced uptake of fluorescent tracer particles indicates diminished endocytic and phagocytic activity under these exposure conditions. Additionally, induction of TLR7-dependent interferon-related genes in response to virus-like stimulation is suppressed. These findings indicate that even non-lethal levels of particulate matter can impair immune function by disrupting cellular uptake mechanisms and innate immune signalling, highlighting an overlooked immunotoxic risk associated with chronic low-dose exposure. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (38)

  • Article
  • Open Access
763 Views
22 Pages

Posidonia oceanica Extract Inhibits VEGF-Induced Angiogenic and Oxidative Responses in Human Endothelial Colony-Forming Cells

  • Francesca Margheri,
  • Cecilia Anceschi,
  • Elena Frediani,
  • Alessandra Marzoppi,
  • Marzia Vasarri,
  • Donatella Degl’Innocenti,
  • Emanuela Barletta,
  • Anna Laurenzana and
  • Anastasia Chillà

17 September 2025

Angiogenesis, the formation of new blood vessels from pre-existing vasculature, is essential for physiological processes such as development and wound healing, but its dysregulation contributes to a range of pathological conditions including cancer,...

  • Review
  • Open Access
1 Citations
2,332 Views
36 Pages

Innovative Analytical Approaches for Food Pesticide Residue Detection: Towards One Health-Oriented Risk Monitoring

  • Alexandra Andreea Botnaru,
  • Ancuta Lupu,
  • Paula Cristina Morariu,
  • Alin Horatiu Nedelcu,
  • Branco Adrian Morariu,
  • Maria Luisa Di Gioia,
  • Vasile Valeriu Lupu,
  • Oana Maria Dragostin,
  • Ioana-Cezara Caba and
  • Emil Anton
  • + 2 authors

16 September 2025

The increasing use of pesticides in agricultural products raises concerns over food safety. Furthermore, uncontrolled pesticide usage on food products can lead to residual levels that exceed the maximum residue limits (MRLs) and are potentially harmf...

  • Article
  • Open Access
751 Views
17 Pages

Age-Stratified Spatial Radiological Risk Assessment of 226Ra 232Th and 40K in Water Surrounding the Geita Gold Mine in Tanzania

  • Jerome M. Mwimanzi,
  • Nils H. Haneklaus,
  • Farida Lolila,
  • Janeth J. Marwa,
  • Mwemezi J. Rwiza and
  • Kelvin M. Mtei

16 September 2025

Long-term ingestion of water contaminated with naturally occurring radioactive material (NORM) may pose health risks. Water around the Geita Gold Mine in Tanzania was assessed by high-purity germanium gamma spectrometry to quantify the activity conce...

  • Article
  • Open Access
1,614 Views
21 Pages

Effects of Different Interventions Aimed at Reducing Dermal and Internal Polycyclic Aromatic Hydrocarbon Exposure Among Firefighters

  • Anne Thoustrup Saber,
  • Marie Frederiksen,
  • Simon Pelle Jensen,
  • Vivi Kofoed-Sørensen,
  • Per Axel Clausen,
  • Anja Julie Huusom,
  • Tanja Carøe,
  • Niels Ebbehøj,
  • Maria Helena Guerra Andersen and
  • Ulla Vogel

16 September 2025

Firefighters are inherently exposed to soot and polycyclic aromatic hydrocarbons (PAHs) at work. In this repeated measures study, we assessed if three different interventions reduced PAH exposure. For each sub-study, the firefighters participated in...

  • Article
  • Open Access
745 Views
19 Pages

15 September 2025

The determination of contaminants of emerging concern (CECs) in the marine environment is performed through many different sampling approaches. Therefore, the main objective of this study was to compare different existing sampling strategies: biofilm...

  • Systematic Review
  • Open Access
2,912 Views
19 Pages

A Systematic Review of Estrogens as Emerging Contaminants in Water: A Global Overview Study from the One Health Perspective

  • Rhitor Lorca da Silva,
  • Marco Antonio Lima e Silva,
  • Tiago Porfírio Teixeira,
  • Thaís Soares Farnesi de Assunção,
  • Paula Pinheiro Teixeira,
  • Wagner Antonio Tamagno,
  • Thiago Lopes Rocha,
  • Julio Cesar de Souza Inácio Gonçalves and
  • Matheus Marcon

13 September 2025

The widespread presence of estrogens in aquatic environments represents a One Health concern, as it simultaneously threatens environmental integrity, wildlife health, and human well-being. These compounds, widely used in human and veterinary medicine...

  • Article
  • Open Access
870 Views
26 Pages

Integrated Assessment of Silver Nanoparticles on Plant Growth and Cytogenotoxicity Using Triticum and Allium Bioassays

  • Simona Elena Pisculungeanu,
  • Liliana Cristina Soare,
  • Oana Alexandra Luțu,
  • Alina Păunescu,
  • Georgiana Cîrstea,
  • Aurelian Denis Negrea,
  • Codruța Mihaela Dobrescu and
  • Nicoleta Anca Ionescu (Șuțan)

12 September 2025

The production and extensive use of silver nanoparticles (AgNPs) in various fields necessitate thorough testing, not only in terms of their potential applications but also regarding the effects they induce on various organisms. In addition, nanoparti...

  • Review
  • Open Access
2 Citations
4,900 Views
42 Pages

The Mechanisms of Lead Toxicity in Living Organisms

  • Anastasiia Generalova,
  • Slavena Davidova and
  • Galina Satchanska

11 September 2025

Lead (Pb) is a non-essential, toxic heavy metal with no known biological function that has caused widespread environmental contamination throughout human history. Pb toxicity represents one of the most persistent environmental health challenges, with...

  • Article
  • Open Access
847 Views
14 Pages

Effects of Azithromycin on the Functioning of the Food Web in Freshwater Plankton

  • Anita Galir,
  • Dubravka Špoljarić Maronić,
  • Filip Stević,
  • Tanja Žuna Pfeiffer,
  • Fran Prašnikar,
  • Nikolina Bek,
  • Eva Penava and
  • Petra Križevac

10 September 2025

High doses of the antibiotic azithromycin in freshwater environments can impact planktonic organisms at both the individual and community levels, influencing interactions at the base of the food web. This study investigated the effects of azithromyci...

  • Article
  • Open Access
812 Views
30 Pages

9 September 2025

Background: Beta-lactamase inhibitors (BLIs) are widely used with beta-lactam antibiotics to combat resistant infections, yet their safety profiles, especially for newer agents, remain underexplored. This study aimed to identify potential adverse eve...

of 4

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
J. Xenobiot. - ISSN 2039-4713