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Journal of Xenobiotics, Volume 16, Issue 3

2026 June - 48 articles

Cover Story: Microplastics (MPs) have transitioned from environmental contaminants to internal pollutants, detectable in human blood and tissues. A clinical pilot study published in the Journal of Xenobiotics evaluates whether food-grade chitosan derived from Procambarus clarkii (PCC) can reduce internal MP burden via gastrointestinal sequestration. Supplementation of 0.8 g/day for 15 days in healthy adults resulted in a 26.3% decrease in blood MP mass concentrations and shifted the distribution toward smaller particle fractions. The control group showed no significant change, suggesting that internal MP levels do not naturally decline. This study provides the first human kinetic evidence that systemic MP levels are modifiable through targeted dietary interventions. View this paper
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Articles (48)

  • Article
  • Open Access
765 Views
20 Pages

This study analyzes the determinants of self-reported behaviours and perceptions associated with pesticide toxicity risk in children using the Social Practice Theory framework, linking individual factors and agricultural practices to understand vulne...

  • Review
  • Open Access
1,645 Views
19 Pages

A Multidisciplinary Review of Phytoremediation Strategies for Heavy Metal-Contaminated African Soils: From Geochemical Assessment to Genetic Enhancement

  • Fatouma Mohamed Abdoul-Latif,
  • Rohit Kumar,
  • Talal Mohamed,
  • Ali Merito and ,
  • N Chinmaya Kumar,
  • Ibrahim Houmed Aboubaker and
  • Pannaga Pavan Jutur
  • + 2 authors+ 0 author

African soils face increasing levels of metal pollution due to industrialization, artisanal mining activities, improper waste management, and enhanced agricultural productivity. However, unlike many organic pollutants, heavy metals do not degrade nat...

  • Article
  • Open Access
1 Citations
1,076 Views
18 Pages

Atmospheric Washout Dynamics of Organic Micropollutants: A Study of PAH, PAE, and BTEX Concentrations in Rainwater Across Northern Serbia

  • Brankica Kartalović,
  • Rastko Tomanović,
  • Kristina Habschied,
  • Alma Mikuška and ,
  • Mirta Sudarić Bogojević,
  • Antonije Žunić and
  • Dora Bjedov
  • + 2 authors+ 0 author

Atmospheric wet deposition represents a major pathway for the transfer of organic micropollutants into terrestrial and aquatic ecosystems. This study investigates the occurrence and spatial distribution of polycyclic aromatic hydrocarbons (PAHs), pht...

(This article belongs to the Special Issue The Silent Crisis: Air Pollution and Its Hidden Impact on Human Health)
  • Article
  • Open Access
1 Citations
1,941 Views
30 Pages

A Network Toxicology Framework for Identification of Immune System Disruption by Per- and Polyfluoroalkyl Substance (PFAS) Mixture: In Silico Analysis

  • Katarina Baralić,
  • Katarina Vidić,
  • Đurđica Marić,
  • Jovana Živanović and ,
  • Aleksandra Buha Djordjevic,
  • Marijana Ćurčić,
  • Zorica Bulat,
  • Biljana Antonijević and
  • Danijela Đukić-Ćosić
  • + 4 authors+ 0 author

Per- and polyfluoroalkyl substances (PFAS) are persistent, chemically stable compounds widely used in daily life. Perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA), perfluorohexanesulfonic acid (PFHxS), and perfluorooctanesulfonic acid (PF...

(This article belongs to the Section Emerging Chemicals)
  • Article
  • Open Access
1,275 Views
13 Pages

Air pollution is a major environmental determinant of premature mortality and population health burden. Liguria represents a vulnerable Mediterranean region due to intense urbanisation, port-related emissions, complex topography and an ageing populat...

  • Article
  • Open Access
1,294 Views
20 Pages

Neurobehavioural Effects of the Methylimidazolium Ionic Liquid M8OI in Rats

  • Tarek M. Abdelghany,
  • Alaa A. Budastour,
  • Ahmed S. Kamel,
  • Sherehan M. Ibrahim and ,
  • Alex Charlton,
  • Simon Wilkinson,
  • Catherine Arden,
  • Noha F. Abdelkader and
  • Matthew C. Wright
  • + 4 authors+ 0 author

M8OI is a cytotoxic methylimidazolium ionic liquid solvent through its binding to the ubiquinone binding site on complex I of the mitochondrial electron transport chain. Given the overlap in terms of toxic mechanism of action with the pesticide roten...

(This article belongs to the Section Emerging Chemicals)
  • Article
  • Open Access
996 Views
13 Pages

The sorption behavior of antibiotics in wastewater treatment systems plays a critical role in determining their environmental fate and removal efficiency. In this study, the sorption of 15 antibiotics representing multiple classes was investigated us...

  • Article
  • Open Access
790 Views
24 Pages

Vascular Endocrine-Disrupting Effects of Bisphenol F and Bisphenol S on Human Umbilical Artery

  • Fatima Abrantes-Soares,
  • Mariana Marques Santos,
  • Melissa Mariana,
  • Margarida Lorigo and
  • Elisa Cairrao

In recent years, bisphenol F (BPF) and bisphenol S (BPS) have been used in several everyday products to replace bisphenol A (BPA), since exposure to BPA has been associated with the development of several pathologies. However, recent studies have als...

(This article belongs to the Special Issue Advances in Toxicological Research on Chemical Entities: Mechanistic Insights and Safety Profiles)
  • Article
  • Open Access
1,192 Views
20 Pages

Maternal Anemia and Pediatric Neurodevelopment in Children from Mothers Exposed to Mixed Heavy Metals in Suriname

  • Anisma R. Gokoel,
  • Arti Shankar,
  • Simran F. Mokiem,
  • Ashna D. Hindori-Mohangoo and ,
  • Maureen Y. Lichtveld,
  • Jeffrey K. Wickliffe and
  • Wilco C. W. R. Zijlmans
  • + 2 authors+ 0 author

Maternal anemia and prenatal exposure to neurotoxic metals are widespread in low- and middle-income countries and may affect early childhood development. In Suriname, where mercury contamination from artisanal gold mining and social disparities coexi...

  • Article
  • Open Access
985 Views
16 Pages

Food Additive Titanium Dioxide (E171) Increases Intracellular Labile Fe2+ Levels and Induces Oxidative Stress and Mitochondrial Dysfunction in H9c2 Cardiomyoblasts

  • Alfredo Cruz-Gregorio,
  • Alejandro Silva-Palacios,
  • Javier A. Belmont-Díaz,
  • María del Pilar Ramos-Godinez and
  • Rebeca López-Marure

Food-grade titanium dioxide (E171) is widely used as a food additive and has raised concerns about its potential systemic toxicity. However, its impact on cardiac cellular metabolism and mitochondrial function remains incompletely understood. In the...

(This article belongs to the Section Nanotoxicology and Nanopharmacology)
  • Article
  • Open Access
1 Citations
1,312 Views
30 Pages

From Ecological Threats to Monitoring Tools: Multi-Contaminant Profiles in Silurus glanis and Procambarus clarkii for Pollution Tracking and Preliminary Food/Feed Safety Assessment

  • Sara Glorio Patrucco,
  • Roberta Giugliano,
  • Alessandra Griglione,
  • Giorgia Zicarelli and ,
  • Camilla Mossotto,
  • Leo Costa,
  • Giuseppe Esposito,
  • Alice Gabetti,
  • Serena Anselmi and
  • Paolo Pastorino
  • + 13 authors+ 8 authors

Invasive alien species (IAS) such as Silurus glanis and Procambarus clarkii represent major ecological threats but may also serve as effective bioindicators of environmental contamination; therefore, this study aimed to evaluate their potential for m...

(This article belongs to the Section Ecotoxicology)
  • Article
  • Open Access
721 Views
16 Pages

Lactic Acid Bacteria as In Vivo Protective Strategy Against Dietary Methylmercury Exposure

  • Luzmila Burbano,
  • Pilar Rodríguez-Viso,
  • Manuel Zúñiga,
  • Vicente Monedero and ,
  • Vicenta Devesa and
  • Dinoraz Vélez
  • + 1 author+ 0 author

The aim of this study was to characterize the toxicokinetics of dietary Hg and to identify lactic acid bacteria (LAB) strains capable of reducing methylmercury (MeHg) accumulation in organs. BALB/c mice and Wistar rats were exposed via drinking water...

  • Review
  • Open Access
2,294 Views
18 Pages

Chronic opioid use disrupts the female endocrine system, affecting the hypothalamic–pituitary–gonadal (HPG), hypothalamic–pituitary–adrenal (HPA), and hypothalamic–pituitary–thyroid (HPT) axes. In women, these disr...

(This article belongs to the Section Emerging Chemicals)
  • Article
  • Open Access
1,103 Views
18 Pages

Tissue-Specific Biomarkers and Bioaccumulation in Mytilus galloprovincialis: Seasonal Anthropogenic Stress in the North Ionian Sea (Calabria, Italy)

  • Maria Assunta Iovine,
  • Mariacristina Filice,
  • Luisa Albarano,
  • Alessia Caferro and ,
  • Sandra Imbrogno,
  • Rosa Mazza,
  • Francesca Esposito,
  • Maria Costantini,
  • Valerio Zupo and
  • Maria Carmela Cerra
  • + 7 authors+ 2 authors

Coastal ecosystems are increasingly threatened by human activities, highlighting the need for sensitive tools to assess environmental risk. An active biomonitoring approach, using the Mediterranean mussel (Mytilus galloprovincialis), was employed to...

(This article belongs to the Section Ecotoxicology)
  • Article
  • Open Access
825 Views
15 Pages

Numerical Simulation of Atmospheric Pollutant Dispersion on Campus: Impacts of Wind Environment and Newly Constructed Buildings’ Height

  • Chongxi Liao,
  • Luxin Ren,
  • Lulu Xu,
  • Renjie Zhao and ,
  • Baocong Zhao,
  • Sihao Lin,
  • Ting Zhang,
  • Yijie Zhuang,
  • Yanpeng Gao and
  • Yuemeng Ji
  • + 5 authors+ 0 author

Toluene, as a common organic solvent in academic laboratories in university campuses, poses potential exposure concerns to students and staff in university campuses. Hence, by using a computational fluid dynamics simulation, we investigated the dispe...

  • Article
  • Open Access
1 Citations
1,338 Views
32 Pages

Subchronic Cadmium-Induced Xenobiotic Toxicity in Male Wistar Rats: Antioxidant and Reproductive Protection by Standardized Silymarin with Molecular Docking Insights

  • Imen Hammami,
  • Fatma Arrari,
  • Rahma Mahjoub,
  • Ridha Ben Ali and ,
  • Haifa El Hentati,
  • Afef Nahdi,
  • Eduardo Alberto López-Maldonado and
  • Emna Talbi
  • + 3 authors+ 0 author

Cadmium is a widespread environmental xenobiotic that poses serious risks to hepatic, renal, and male reproductive functions. Natural compounds such as silymarin, a bioactive extract from Silybum marianum, have gained attention for their protective p...

(This article belongs to the Topic Environmental Exposure and Health Risks for Vulnerable Populations)
  • Article
  • Open Access
1,244 Views
26 Pages

Sorghum and Hemp Responses to Plant Growth-Promoting Microorganism Inoculation in Metal-Contaminated Dredged Sediment: A System-Level Assessment Under Environmentally Relevant Outdoor Pot Conditions

  • Marko Šolić,
  • Nina Đukanović,
  • Tamara Apostolović,
  • Jelena Beljin and ,
  • Irina Jevrosimov,
  • Dragana Tamindžija,
  • Ivana Bajić,
  • Stanko Milić,
  • Tijana Zeremski and
  • Snežana Maletić
  • + 6 authors+ 1 author

Metal-contaminated dredged sediments represent heterogeneous environmental matrices in which remediation responses are frequently constrained by elevated background metal loads and complex geochemical conditions. Within such systems, phytoremediation...

(This article belongs to the Section Ecotoxicology)
  • Article
  • Open Access
2,644 Views
24 Pages

Exposure to Glyphosate and Chlorpyrifos Induces Oxidative Stress, Potentially Impacting Sex Determination in Zebrafish (Danio rerio)

  • Daniela Arias-Camacho,
  • Brian Antonio Rochin-Peraza,
  • Miguel Betancourt-Lozano,
  • Selene Abad-Rosales and ,
  • José Basilio Heredia,
  • Nayely Leyva-López,
  • Samuel Calderón-Liévanos and
  • Alejandra García-Gasca
  • + 3 authors+ 0 author

The widespread use of pesticides in agriculture has increased their levels in water bodies, threatening aquatic ecosystems. Among these, glyphosate and chlorpyrifos are widely used in Mexico and can cause toxic effects even at low doses. In aquatic o...

(This article belongs to the Section Ecotoxicology)
  • Article
  • Open Access
1,142 Views
20 Pages

Phenotypic Subacute Toxicity Assessment of Intranasally Administered Larixyl Acetate: Implications for Potential Airway Applications

  • Zaina Kalaji,
  • Ibrahim Hachim,
  • Marwa Almazrouei,
  • Hanaa Habbal and ,
  • Vidya Bijosh Mohan,
  • Mohammad G. Mohammad,
  • Rifat Hamoudi and
  • Rabih Halwani
  • + 3 authors+ 0 author

Larixyl acetate, a primary component of Larch turpentine, is a naturally occurring compound with a broad spectrum of medicinal properties, including anti-inflammatory effects. It is a potent and selective inhibitor of TRPC6, a widely expressed Ca2+ c...

(This article belongs to the Section Natural Products/Herbal Medicines)
  • Review
  • Open Access
2 Citations
1,402 Views
26 Pages

Xenobiotic Sulforaphane in Head and Neck Cancer: Beyond the Nrf2 Pathway

  • Alessandro Polizzi,
  • Rossella Rotondo,
  • Sabrina Donati Zeppa,
  • Monia Cecati and ,
  • Magdalena Smolik,
  • Valentina Schiavoni,
  • Angelo Montana,
  • Valentina Pozzi,
  • Davide Sartini and
  • Gaetano Isola
  • + 6 authors+ 1 author

Head and neck cancers (HNCs) represent a major global health burden and remain associated with substantial morbidity and limited therapeutic options, particularly in advanced or recurrent disease. Increasing interest has focused on naturally derived...

  • Article
  • Open Access
1,179 Views
17 Pages

Pesticide formulations may influence toxicological outcomes beyond the intrinsic properties of active ingredients; however, these differences are often overlooked in regulatory risk assessment. Using human liver HepG2 cells, this study compared the c...

  • Case Report
  • Open Access
1,948 Views
12 Pages

Acute Anticholinergic Toxic Syndrome Due to Scopolamine Exposure: A Case Report with Possible Drug-Facilitated Administration

  • Stanila Stoeva-Grigorova,
  • Ivanesa Yarabanova,
  • Maya Radeva-Ilieva,
  • Galina Uzunova and ,
  • Georgi Bonchev,
  • Ivanka Gospodinova,
  • Violeta Borisova,
  • Elmira Vicheva,
  • Simeon Marinov and
  • Snezha Zlateva
  • + 6 authors+ 1 author

Introduction: Scopolamine is a tropane alkaloid and non-selective muscarinic receptor antagonist capable of inducing a central anticholinergic toxidrome with pronounced neuropsychiatric and autonomic manifestations. Despite its well-characterized pha...

  • Article
  • Open Access
997 Views
19 Pages

Individual and Combined Effects of Legacy and Emerging Contaminants on the Blue Crab Callinectes sapidus: Mercury and Bisphenol S as a Case Study

  • Jacopo Fabrello,
  • Giovanni Martino Rigodanza,
  • Francesco Boldrin,
  • Federico Caicci and ,
  • Marco Munari and
  • Valerio Matozzo
  • + 1 author+ 0 author

This study investigated the individual and combined effects of mercury (as HgCl2) and Bisphenol S (BPS) on the blue crab Callinectes sapidus, focusing on biomarkers measured in hemolymph, gills, and hepatopancreas and ultrastructure (transmission ele...

(This article belongs to the Special Issue New Insights into the Effects of Multi-Pollutant Mixtures on the Environment and Populations)
  • Article
  • Open Access
831 Views
18 Pages

Ameliorative Effects of Berberine Against Acetamiprid-Induced Toxicity in the Testes of Rats: A Computational and Histological Insight

  • Jagjeet Singh,
  • Annu Phogat,
  • Reena Sheoran,
  • Arun Hasanpuri and ,
  • Vijay Kumar,
  • Manoj Kumar Yadav and
  • Vinay Malik
  • + 2 authors+ 0 author

Background: Acetamiprid (ACMP) exposure mediates a variety of pathological complications, including testicular toxicity. Berberine (BBR) is a plant-derived alkaloid with potential pharmacological properties. This study sought to evaluate the ameliora...

(This article belongs to the Section Natural Products/Herbal Medicines)
  • Systematic Review
  • Open Access
1,553 Views
32 Pages

Antibiotic Resistance Genes in Wastewater: A Systematic PRISMA-Guided Review on Risk, Genetic Transfer, and the Effectiveness of the Photo-Fenton Process for Their Removal

  • María del Rocío Duarte-Martínez,
  • Aldo Amaro-Reyes,
  • Juan Campos-Guillen,
  • Miguel Angel Ramos-López and ,
  • Eloy Rodríguez-de León,
  • Monserrat Escamilla-García,
  • Vanessa Vallejo-Becerra,
  • Alejandra Álvarez-López,
  • Yesenia Mendoza-Burguete and
  • José Alberto Rodríguez-Morales
  • + 9 authors+ 4 authors

Antimicrobial resistance (AMR) constitutes a growing global threat, facilitated by the dissemination of antibiotic resistance genes (ARGs) through wastewater treatment plants (WWTPs). This systematic review, conducted following the PRISMA guidelines,...

(This article belongs to the Special Issue Emerging Contaminants as Vectors of Global Change: Ecotoxicology, Bioaccumulation and Risk)
  • Review
  • Open Access
4 Citations
3,410 Views
47 Pages

Emerging contaminants (ECs) and microplastics (MPs) are increasingly detected in surface waters, wastewaters, and drinking water, often as complex mixtures, transformation products, and particle-associated burdens that challenge routine monitoring. T...

(This article belongs to the Special Issue Emerging Contaminants as Vectors of Global Change: Ecotoxicology, Bioaccumulation and Risk)
  • Article
  • Open Access
9 Citations
3,961 Views
28 Pages

Microplastics (MPs) are emerging contaminants that have been detected in human blood and tissues, raising concerns regarding systemic exposure and potential health effects. Internal MP burden mitigation techniques, nevertheless, are yet largely unexp...

  • Article
  • Open Access
1 Citations
901 Views
14 Pages

Real-World Traffic-Polluted Air and Its Impact on a 3D Model of the Human Airway Epithelium

  • Michal Sima,
  • Helena Libalova,
  • Zuzana Simova,
  • Kristyna Vrbova and ,
  • Antonin Ambroz,
  • Jiri Klema,
  • Lubos Dittrich,
  • Michal Vojtisek-Lom and
  • Pavel Rossner
  • + 4 authors+ 0 author

Exposure to air pollution is linked to adverse health outcomes. To better reflect real-world conditions, we employed a mobile exposure system enabling direct field exposure of the human airway epithelial model MucilAir™ to ambient air in a traf...

(This article belongs to the Special Issue New Insights into the Effects of Multi-Pollutant Mixtures on the Environment and Populations)
  • Article
  • Open Access
1 Citations
1,640 Views
21 Pages

Tissue-Specific Accumulation and Dietary Risk of Arsenic and Other Potentially Toxic Elements in Retail Meats

  • Syed Sayyam Abbas,
  • Syed Ali Musstjab Akber Shah Eqani,
  • Ismat Nawaz,
  • Mansoor A. Alghamdi and ,
  • Ahmed S. Summan,
  • Abdul Qadir,
  • Shabbar Abbas,
  • Iqra Rasheed,
  • Syeda Maria Ali and
  • Nadeem Ali
  • + 8 authors+ 3 authors

Data on arsenic (As) and other potentially toxic elements (PTEs) in Pakistani retail meats are limited, constraining evidence-based dietary risk assessment and management. This study aimed to determine the concentrations and profiles of As and seven...

(This article belongs to the Special Issue Selected Papers from the 1st International Online Conference on Xenobiotics (IOCXe 2026))
  • Article
  • Open Access
1 Citations
882 Views
22 Pages

Vehicle Cabins as Hotspots of Brominated Flame Retardants: Legacy–Replacement Profiles, Sources, and Human Exposure in a Hot-Climate Environment

  • Muhammad Salman Zeb,
  • Mansour A. Alghamdi,
  • Ahmed Summan,
  • Javed Nawab and ,
  • Muhammad Imtiaz Rashid and
  • Nadeem Ali
  • + 1 author+ 0 author

Brominated flame retardants (BFRs) are widely used in automotive polymers and electronic components, yet vehicles remain an under-characterized and potentially high-exposure microenvironment, particularly in hot climates. This study provides the firs...

(This article belongs to the Special Issue Selected Papers from the 1st International Online Conference on Xenobiotics (IOCXe 2026))
  • Article
  • Open Access
1 Citations
954 Views
22 Pages

The increasing fragmentation of plastic debris into nanosized particles represents a threat to freshwater ecosystems, yet the biological effects of nanoplastics (NPs) on freshwater invertebrates remain poorly understood. This study investigated tissu...

(This article belongs to the Special Issue Xenobiotics in Aquatic Ecosystems: Fate, Toxicity, and Sustainable Remediation)
  • Article
  • Open Access
901 Views
25 Pages

The interplay between the environmental exposome and the cancer genome remains a critical gap in precision oncology. While somatic mutational signatures—genomic fossils imprinted by exposures such as ultraviolet radiation; tobacco smoke; and in...

(This article belongs to the Topic Environmental Exposure and Health Risks for Vulnerable Populations)
  • Article
  • Open Access
1,213 Views
24 Pages

Trans-Cinnamaldehyde as an Environmentally Low-Impact Phytosanitary: Evaluation of Its Toxicity Toward Aquatic and Terrestrial Non-Target Species

  • Natalia Ferrando,
  • Elisa Langa,
  • Laura Botello-Morte,
  • Pedro Rodríguez-López and ,
  • Diego Ballestero and
  • María Rosa Pino-Otín
  • + 1 author+ 0 author

Trans-cinnamaldehyde (CIN), the main component of cinnamon essential oil, is a promising sustainable alternative to synthetic pesticides. Despite its use, ecotoxicological data on non-target species remain fragmented. This study systematically evalua...

  • Article
  • Open Access
953 Views
12 Pages

Glyphosate and its primary metabolite aminomethylphosphonic acid (AMPA) are widely detected in aquatic environments, yet their combined effects on fish remain insufficiently understood. This study used label-free blood plasma proteomic profiling to e...

(This article belongs to the Special Issue Environmental Toxicology and Animal Health: 2nd Edition)
  • Article
  • Open Access
1,358 Views
22 Pages

Short-Term Consumption of Hot Beverages in Polystyrene Cups and Early Biomarkers of Biological Effect: A Single-Arm Longitudinal Human Biomonitoring Pilot Study

  • Iman Al-Saleh,
  • Ghofran Al-Qudaihi,
  • Yara Aljerayed,
  • Kafa Abuhdeeb and ,
  • Rola Elkhatib,
  • Hissah Alnuwaysir,
  • Mashael Alsubaie and
  • Norah Alotaibi
  • + 3 authors+ 0 author

Styrene, a constituent of polystyrene food-contact materials, can migrate into hot beverages, but data on short-term consumer exposure and associated biological responses remain limited. In this single-arm longitudinal human biomonitoring pilot study...

(This article belongs to the Section Emerging Chemicals)
  • Article
  • Open Access
1,407 Views
18 Pages

Geochemistry, Speciation, and Health Risks from Potentially Toxic Elements in Street Dust of Mbarara City, Uganda

  • Hassan Omary Kumenya,
  • Irene Nalumansi,
  • Christopher Angiro,
  • Ivan Kiganda and ,
  • Timothy Omara and
  • Emmanuel Ntambi
  • + 1 author+ 0 author

In equatorial Africa, rapid urbanization has increased city populations and particulate matter emissions. Street dust is a visual indicator that can be used to track urban pollution. In the present study, the total concentration and speciation of 10...

(This article belongs to the Section Ecotoxicology)
  • Article
  • Open Access
1 Citations
773 Views
18 Pages

Exposure to Endocrine Disruptors and Stress Hormones Across Pregnancy Trimesters: Links with Maternal Telomere Length

  • Elena Vakonaki,
  • Eleftheria Hatzidaki,
  • Stella Baliou,
  • Maria Marmara and ,
  • Athanasios Alegakis,
  • Eleftheria Mylonaki,
  • Zoi Volonaki,
  • Fanourios Makrygiannakis,
  • Aristides Tsatsakis and
  • Manolis N. Tzatzarakis
  • + 5 authors+ 0 author

Background: Exposure of pregnant women to stress and endocrine-disrupting chemicals (EDCs) during pregnancy can have a substantial impact on mother and infant health. We investigated the concentrations of EDCs, such as parabens (PBs) and triclosan (T...

(This article belongs to the Section Emerging Chemicals)
  • Article
  • Open Access
1,374 Views
17 Pages

Microplastic Pollution in Agricultural Waters in the Mississippi Delta

  • Edward Heinen,
  • James V. Cizdziel,
  • Boluwatife S. Olubusoye,
  • Ruojia Li and ,
  • Matthew T. Moore and
  • Lindsey M. Witthaus
  • + 1 author+ 0 author

Microplastic (MP) pollution in agricultural settings is an emerging field of study, with interest focusing on potential resource contamination of soil and water due to the use of plastic materials in farming practices. The Mississippi Delta, a highly...

(This article belongs to the Special Issue (Micro)plastic Pollution: From Monitoring to Toxicity in All Environments)
  • Article
  • Open Access
1,388 Views
12 Pages

Aim: The aim of this study was to develop and validate a reliable HS-GC-FID/FID method for the determination of ethanol and other low-molecular-weight volatile compounds in biological fluids for forensic applications. Method: The method is based on h...

(This article belongs to the Section Emerging Chemicals)
  • Article
  • Open Access
646 Views
20 Pages

Congener-Specific Dietary Exposure and Predicted Organ-Specific Toxicity of Halogenated PAHs in Populations Living near a Coking Industrial Area

  • Yanpeng Gao,
  • Weijie Lu,
  • Yibo Zhang,
  • Mingze Geng and ,
  • Xianglong Luo,
  • Yuemeng Ji and
  • Yang-Guang Gu
  • + 2 authors+ 0 author

Halogenated polycyclic aromatic hydrocarbons (HPAHs) are persistent contaminants with elevated toxicity, yet dietary exposure data remain limited. Here, we systematically assessed dietary HPAHs using 87 duplicate diet samples collected from populatio...

  • Article
  • Open Access
1,221 Views
23 Pages

Genotoxic Damage and microRNA Dysregulation in Firefighters: An Integrated Biomonitoring Case Study

  • Claudia Cipollone,
  • Riccardo Mastrantonio,
  • Paola Mozzoni,
  • Giada Mastrangeli and ,
  • Massimo Corradi,
  • Stefano Renzetti,
  • Veronica Saponara,
  • Maria Nicastro,
  • Delia Cavallo and
  • Leila Fabiani
  • + 16 authors+ 11 authors

Firefighters are potentially exposed to multiple harmful substances, and their activities are classified as carcinogenic to humans. This case study assessed early genotoxic damage (fpg-comet and BMCyt assays) and epigenetic alterations (seven circula...

  • Article
  • Open Access
1,259 Views
11 Pages

Determination of Various Drugs of Abuse in Oral Fluid by a Fabric Phase Sorptive Extraction–LC-MS/MS Method

  • Dimitra Florou,
  • Thalia Vlachou,
  • Amvrosios Orfanidis,
  • Vasilios Sakkas and
  • Vassiliki A. Boumba

Toxicological testing for drugs of abuse (DOAs) is an essential tool for healthcare practitioners and law enforcement agencies. Oral fluid (OF) is an alternative biological fluid for detecting recent DOA intake and is widely employed in forensic inve...

(This article belongs to the Section Nanotoxicology and Nanopharmacology)
  • Article
  • Open Access
1 Citations
1,307 Views
19 Pages

Antioxidant Therapy Reverses Hepatotoxicity Induced by Microcystin-LR in a Cellular Model of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

  • Apurva Lad,
  • Jason Kindle,
  • Prajwal Hegde,
  • Gabriel G. Kleer and ,
  • Andrew L. Kleinhenz,
  • Johnna A. Birbeck,
  • Judy Westrick,
  • Nicholas J. Peraino,
  • Terry D. Hinds and
  • David J. Kennedy
  • + 8 authors+ 3 authors

Microcystin-LR (MC-LR) is a potent hepatotoxin that has been shown to cause liver damage even at doses lower than the established Low Observable Adverse Effect Level (LOAEL) of 200 μg/kg in animal models. We have previously observed that low-dose...

  • Article
  • Open Access
1 Citations
1,184 Views
25 Pages

Rabbit Litter-Derived Carbon Materials for Organophosphate Pesticide Mitigation: Adsorption Performance, Neurotoxicity Reduction, and Genotoxicity Assessment

  • Tamara Lazarević-Pašti,
  • Tamara Terzić,
  • Andreja Leskovac,
  • Sandra Petrović and ,
  • Vedran Milanković,
  • Nevena Radivojević,
  • Jugoslav Krstić,
  • Katarina Kokanov Stanković,
  • Ana Jocic and
  • Igor Pašti
  • + 6 authors+ 1 author

Organophosphate pesticides are widely used agricultural chemicals that pose significant environmental and health risks due to their neurotoxicity, which is associated with inhibition of acetylcholinesterase. In this study, carbon materials derived fr...

  • Article
  • Open Access
2 Citations
1,566 Views
25 Pages

Apoptosis and Cell Cycle Dysregulation in Ampligo® 150 ZC-Induced Nephrotoxicity in Female Rabbits: Protective Effects of Thymus vulgaris Essential Oil and Vitamin C

  • Louisa Bechohra,
  • Chahrazed Makhlouf,
  • Hassina Khaldoun,
  • Samira Aouichat and ,
  • Amina Settar,
  • Dalila Tarzaali,
  • Nacera Lemlikchi,
  • Amina Bouhallel,
  • Yasmine Oularbi and
  • Nacima Djennane
  • + 6 authors+ 1 author

The widespread use of modern insecticide formulations underscores the need for mechanistic evaluation of their potential renal toxicity. This study investigated the nephrotoxic effects of Ampligo® 150 ZC, a binary formulation of lambda-cyhalothri...

(This article belongs to the Topic Disease Risks and Toxic Pathway from Environmental Chemical Exposure)
  • Article
  • Open Access
1 Citations
1,006 Views
16 Pages

Effects of Cannabidiol on Behavior and Oxidative Stress in a Rat Model of Depression Under Chronic Stress

  • George Jîtcă,
  • László-István Bába,
  • Ingrid Evelin Mehelean,
  • Ana Natalia Maier and ,
  • Ioana-Irina Popoviciu,
  • Tudor-Nicolae Cotruş and
  • Erzsébet Májai
  • + 2 authors+ 0 author

According to the most recent data published by the World Health Organization (WHO), it is estimated that approximately 332 million persons worldwide suffer from depression. The relationship between depression and alcohol consumption is complex and bi...

  • Article
  • Open Access
4 Citations
2,915 Views
15 Pages

The Association of Microplastics in Peripheral Blood and Pulmonary Disease: A Pilot Study

  • Scott A. Helgeson,
  • Hossny Alaws,
  • Mohamed I. Ibrahim,
  • Augustine S. Lee and ,
  • Danielle H. W. Vlecken and
  • Hassan Z. Baig
  • + 1 author+ 0 author

Microplastics may pose health risks, particularly for chronic lung diseases. Clarifying the link between circulating microplastics and pulmonary disease is vital for shaping research and interventions. The objective of this study was to evaluate whet...

  • Article
  • Open Access
1 Citations
1,618 Views
15 Pages

Selective Cytogenetic Responses to Nano-Fertilizer Co-Exposure in Allium cepa L.: Implications for Sublethal Phytotoxicity in Agroecosystems

  • Olivia Torres-Bugarín,
  • Alejandro Sánchez-González,
  • María Luisa Ramos-Ibarra,
  • Idalia Yazmín Castañeda-Yslas and ,
  • Nina Bogdanchikova,
  • Alexey Pestryakov and
  • María Evarista Arellano-García
  • + 2 authors+ 0 author

The intensive use of agricultural inputs and the increasing incorporation of nano-materials into crop management practices raise concerns about their ecotoxicological interactions in plant systems. This study evaluated phytotoxicity, cytotoxicity, an...

(This article belongs to the Topic Disease Risks and Toxic Pathway from Environmental Chemical Exposure)
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J. Xenobiotics - ISSN 2039-4713