You are currently viewing a new version of our website. To view the old version click .

Viruses, Volume 12, Issue 7

July 2020 - 94 articles

Cover Story: The large capsids, or heads, of giant phages are unusual, containing not only their long genomes, but in many instances a large amount of protein that is ejected into the host bacterial cell. How giant phage heads form is mostly undefined. In this study, the proteolysis of head proteins by the prohead protease was shown to be essential for head maturation of giant Salmonella virus SPN3US. In the absence of proteolysis, precursor head structures remained anchored to the Salmonella inner membrane, thus preventing packaging of the genomic DNA and addition of the tail. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (94)

  • Article
  • Open Access
8 Citations
4,617 Views
16 Pages

The Mutation of the Genes Related to Neurovirulence in HSV-2 Produces an Attenuated Phenotype in Mice

  • Lei Liu,
  • Jishuai Cheng,
  • Tangwei Mou,
  • Ying Zhang,
  • Xingli Xu,
  • Jingjing Zhang,
  • Xueqi Li,
  • Xiao Feng,
  • Xiangxiong Xu and
  • Yun Liao
  • + 4 authors

17 July 2020

HSV-2 (Herpes simplex virus type 2) is a critical viral agent that mainly causes genital herpes and life-long latent infection in the dorsal root ganglia. Gene modification via CRISPR/Cas9 Clustered regularly interspaced short palindromic repeat sequ...

  • Article
  • Open Access
9 Citations
3,366 Views
13 Pages

17 July 2020

The zika virus (ZIKV) is a neurotropic virus that causes congenital abnormalities in babies when they are infected in utero. Some studies have reported these congenital abnormalities result from ZIKV attacking neural progenitor cells within the brain...

  • Review
  • Open Access
16 Citations
6,373 Views
21 Pages

Brothers in Arms: Structure, Assembly and Function of Arenaviridae Nucleoprotein

  • Nicolas Papageorgiou,
  • Maria Spiliopoulou,
  • Thi-Hong Van Nguyen,
  • Afroditi Vaitsopoulou,
  • Elsie Yekwa Laban,
  • Karine Alvarez,
  • Irene Margiolaki,
  • Bruno Canard and
  • François Ferron

17 July 2020

Arenaviridae is a family of viruses harbouring important emerging pathogens belonging to the Bunyavirales order. Like in other segmented negative strand RNA viruses, the nucleoprotein (NP) is a major actor of the viral life cycle being both (i) the n...

  • Review
  • Open Access
126 Citations
13,460 Views
23 Pages

Aphid Transmission of Potyvirus: The Largest Plant-Infecting RNA Virus Genus

  • Kiran R. Gadhave,
  • Saurabh Gautam,
  • David A. Rasmussen and
  • Rajagopalbabu Srinivasan

17 July 2020

Potyviruses are the largest group of plant infecting RNA viruses that cause significant losses in a wide range of crops across the globe. The majority of viruses in the genus Potyvirus are transmitted by aphids in a non-persistent, non-circulative ma...

  • Article
  • Open Access
15 Citations
4,562 Views
18 Pages

17 July 2020

The complex overlap in waterfowl migratory pathways across the world has established numerous occurrences of genetic reassortment and intercontinental spread of avian influenza virus (AIV) over long distances, thereby calling for huge efforts and tar...

  • Article
  • Open Access
10 Citations
5,399 Views
20 Pages

Decrypting the Origin and Pathogenesis in Pregnant Ewes of a New Ovine Pestivirus Closely Related to Classical Swine Fever Virus

  • Miaomiao Wang,
  • Enrica Sozzi,
  • José Alejandro Bohórquez,
  • Mònica Alberch,
  • Joan Pujols,
  • Guillermo Cantero,
  • Alessandra Gaffuri,
  • Davide Lelli,
  • Rosa Rosell and
  • Albert Bensaid
  • + 4 authors

17 July 2020

This study shows the origin and the pathogenic role of a novel ovine pestivirus (OVPV) isolated in 2017 in Italy, as a pathogenic agent causing severe abortions after infection in pregnant ewes and high capacity for virus trans-placental transmission...

  • Article
  • Open Access
21 Citations
5,840 Views
17 Pages

Rotaviruses Associate with Distinct Types of Extracellular Vesicles

  • Pavel Iša,
  • Arianna Pérez-Delgado,
  • Iván R. Quevedo,
  • Susana López and
  • Carlos F. Arias

16 July 2020

Rotaviruses are the leading cause of viral gastroenteritis among children under five years of age. Rotavirus cell entry has been extensively studied; however, rotavirus cell release is still poorly understood. Specifically, the mechanism by which rot...

  • Article
  • Open Access
4 Citations
4,462 Views
19 Pages

MAVS Genetic Variation Is Associated with Decreased HIV-1 Replication In Vitro and Reduced CD4+ T Cell Infection in HIV-1-Infected Individuals

  • Melissa Stunnenberg,
  • Lisa van Pul,
  • Joris K. Sprokholt,
  • Karel A. van Dort,
  • Sonja I. Gringhuis,
  • Teunis B. H. Geijtenbeek and
  • Neeltje A. Kootstra

16 July 2020

The mitochondrial antiviral protein MAVS is a key player in the induction of antiviral responses; however, human immunodeficiency virus 1 (HIV-1) is able to suppress these responses. Two linked single nucleotide polymorphisms (SNPs) in the MAVS gene...

  • Review
  • Open Access
33 Citations
7,345 Views
18 Pages

The Regulation of Flavivirus Infection by Hijacking Exosome-Mediated Cell–Cell Communication: New Insights on Virus–Host Interactions

  • José Manuel Reyes-Ruiz,
  • Juan Fidel Osuna-Ramos,
  • Luis Adrián De Jesús-González,
  • Selvin Noé Palacios-Rápalo,
  • Carlos Daniel Cordero-Rivera,
  • Carlos Noe Farfan-Morales,
  • Arianna Mahely Hurtado-Monzón,
  • Carla Elizabeth Gallardo-Flores,
  • Sofía L. Alcaraz-Estrada and
  • Juan Santiago Salas-Benito
  • + 1 author

16 July 2020

The arthropod-borne flaviviruses are important human pathogens, and a deeper understanding of the virus–host cell interaction is required to identify cellular targets that can be used as therapeutic candidates. It is well reported that the flav...

  • Article
  • Open Access
14 Citations
4,358 Views
9 Pages

Genotypic Characterization of Epstein Barr Virus in Blood of Patients with Suspected Nasopharyngeal Carcinoma in Ghana

  • Richmond Ayee,
  • Maame Ekua Oforiwaa Ofori,
  • Emmanuel Ayitey Tagoe,
  • Sylvester Languon,
  • Kafui Searyoh,
  • Louis Armooh,
  • Estella Bilson-Amoah,
  • Kenneth Baidoo,
  • Emmanuel Kitcher and
  • Edward Wright
  • + 1 author

16 July 2020

Nasopharyngeal cancer (NPC) is associated with Epstein Barr virus (EBV) infection. However different viral strains have been implicated in NPC worldwide. This study aimed to detect and characterize EBV in patients diagnosed with NPC in Ghana. A total...

of 10

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Viruses - ISSN 1999-4915