Viral Genomics: Elucidating Virology in a Metagenomic World

Dear Colleagues,

Viruses are one of the most prolific entities on earth, yet it has only been with the advent of modern molecular technologies and tools that we have begun to unearth the true breadth of viral diversity present. Recent advancements in high throughput methodology and sequencing have enabled characterization of viruses across each nucleic acid type and in many of their forms, such as proviruses, virions, and extracellular nucleic acid. These advancements have identified novel viruses and obtained full genomes leading to a new paradigm, where viral genomes are used to investigate viral diversity, molecular dynamics, evolution, and ecology, greatly expanding the known virosphere. To buttress these efforts, other technologies, such as stable isotope probing and bioorthogonal noncanonical amino acid tagging, can be used to provide increased resolution on viruses, revealing their activity and replication efficiency. This special issue aims to cover recent developments in understanding viral genetic diversity, evolution, and ecology using ‘omic approaches to analyze viral genomes.

Assoc. Prof. Arvind Varsani
Dr. Simona J. Kraberger
Dr. Gareth Trubl
Guest Editors

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