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Marine Drugs, Volume 18, Issue 10

2020 October - 36 articles

Cover Story: Cyanobacteria of the genus Leptolyngbya are found widely in natural ecosystems and participate in many ecological phenomena, such as nitrogen fixation, photosynthesis, and algal blooms. In this review, we summarize scientific studies to date on the ecology, chemistry, biochemistry, and pharmacology of this genus. The emerging broad view of the genus Leptolyngbya and its capacity for production of bioactive natural products provides new insights and perspectives on its metabolic capacities, as well as its role in the ecology of tropical reef systems. View this paper.
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Articles (36)

  • Article
  • Open Access
32 Citations
4,406 Views
12 Pages

Antibacterial Activity of Chromomycins from a Marine-Derived Streptomyces microflavus

  • Eunji Cho,
  • Oh-Seok Kwon,
  • Beomkoo Chung,
  • Jayho Lee,
  • Jeongyoon Sun,
  • Jongheon Shin and
  • Ki-Bong Oh

21 October 2020

A marine-derived actinomycete (Streptomyces sp. MBTI36) exhibiting antibacterial activities was investigated in the present study. The strain was identified using genetic techniques. The 16S rDNA sequence of the isolate indicated that it was most clo...

  • Article
  • Open Access
14 Citations
4,241 Views
12 Pages

Sodium Alginate as a Potential Therapeutic Filler: An In Vivo Study in Rats

  • Masanori Mori,
  • Rintaro Asahi,
  • Yoshihiro Yamamoto,
  • Takanobu Mashiko,
  • Kayo Yoshizumi,
  • Natsumi Saito,
  • Takako Shirado,
  • Yunyan Wu and
  • Kotaro Yoshimura

19 October 2020

Filler injection demand is increasing worldwide, but no ideal filler with safety and longevity currently exists. Sodium alginate (SA) is the sodium salt of alginic acid, which is a polymeric polysaccharide obtained by linear polymerization of two typ...

  • Article
  • Open Access
34 Citations
5,632 Views
13 Pages

Induction of Natural Defenses in Tomato Seedlings by Using Alginate and Oligoalginates Derivatives Extracted from Moroccan Brown Algae

  • Meriem Aitouguinane,
  • Soukaina Bouissil,
  • Anouar Mouhoub,
  • Halima Rchid,
  • Imen Fendri,
  • Slim Abdelkafi,
  • Mohamed Didi Ould El-Hadj,
  • Zakaria Boual,
  • Pascal Dubessay and
  • Cédric Delattre
  • + 5 authors

19 October 2020

Polysaccharides extracted from marine algae have attracted much attention due to their biotechnological applications, including therapeutics, cosmetics, and mainly in agriculture and horticulture as biostimulants, biofertilizers, and stimulators of t...

  • Article
  • Open Access
15 Citations
5,077 Views
18 Pages

Design, Synthesis and In Vitro Experimental Validation of Novel TRPV4 Antagonists Inspired by Labdane Diterpenes

  • Sarah Mazzotta,
  • Gabriele Carullo,
  • Aniello Schiano Moriello,
  • Pietro Amodeo,
  • Vincenzo Di Marzo,
  • Margarita Vega-Holm,
  • Rosa Maria Vitale,
  • Francesca Aiello,
  • Antonella Brizzi and
  • Luciano De Petrocellis

18 October 2020

Labdane diterpenes are widespread classes of natural compounds present in variety of marine and terrestrial organisms and plants. Many of them represents “natural libraries” of compounds with interesting biological activities due to diffe...

  • Article
  • Open Access
21 Citations
4,232 Views
17 Pages

Viridicatol Isolated from Deep-Sea Penicillium Griseofulvum Alleviates Anaphylaxis and Repairs the Intestinal Barrier in Mice by Suppressing Mast Cell Activation

  • Zhendan Shu,
  • Qingmei Liu,
  • Cuiping Xing,
  • Yafen Zhang,
  • Yu Zhou,
  • Jun Zhang,
  • Hong Liu,
  • Minjie Cao,
  • Xianwen Yang and
  • Guangming Liu

16 October 2020

Viridicatol is a quinoline alkaloid isolated from the deep-sea-derived fungus Penicillium griseofulvum. The structure of viridicatol was unambiguously established by X-ray diffraction analysis. In this study, a mouse model of ovalbumin-induced food a...

  • Article
  • Open Access
30 Citations
4,848 Views
19 Pages

N-Docosahexaenoylethanolamine Attenuates Neuroinflammation and Improves Hippocampal Neurogenesis in Rats with Sciatic Nerve Chronic Constriction Injury

  • Anna A. Tyrtyshnaia,
  • Evgenia L. Egorova,
  • Anna A. Starinets,
  • Arina I. Ponomarenko,
  • Ekaterina V. Ermolenko and
  • Igor V. Manzhulo

15 October 2020

Chronic neuropathic pain is a condition that causes both sensory disturbances and a variety of functional disorders, indicating the involvement of various brain structures in pain pathogenesis. One of the factors underlying chronic neuropathic pain i...

  • Article
  • Open Access
10 Citations
5,200 Views
25 Pages

Applying a Chemogeographic Strategy for Natural Product Discovery from the Marine Cyanobacterium Moorena bouillonii

  • Christopher A. Leber,
  • C. Benjamin Naman,
  • Lena Keller,
  • Jehad Almaliti,
  • Eduardo J. E. Caro-Diaz,
  • Evgenia Glukhov,
  • Valsamma Joseph,
  • T. P. Sajeevan,
  • Andres Joshua Reyes and
  • William H. Gerwick
  • + 5 authors

14 October 2020

The tropical marine cyanobacterium Moorena bouillonii occupies a large geographic range across the Indian and Western Tropical Pacific Oceans and is a prolific producer of structurally unique and biologically active natural products. An ensemble of c...

  • Review
  • Open Access
34 Citations
7,549 Views
26 Pages

Marine Antithrombotics

  • Rohini Dwivedi and
  • Vitor H. Pomin

13 October 2020

Thrombosis remains a prime reason of mortality worldwide. With the available antithrombotic drugs, bleeding remains the major downside of current treatments. This raises a clinical concern for all patients undergoing antithrombotic therapy. Novel ant...

  • Article
  • Open Access
17 Citations
4,161 Views
10 Pages

Hatsusamides A and B: Two New Metabolites Produced by the Deep-Sea-Derived Fungal Strain Penicillium steckii FKJ-0213

  • Hirotaka Matsuo,
  • Rei Hokari,
  • Aki Ishiyama,
  • Masato Iwatsuki,
  • Mayuka Higo,
  • Kenichi Nonaka,
  • Yuriko Nagano,
  • Yōko Takahashi,
  • Satoshi Ōmura and
  • Takuji Nakashima

12 October 2020

Two new nitrogen-containing metabolites, designated hatsusamide A (1) and B (2), were isolated from a culture broth of Penicilliumsteckii FKJ-0213 together with the known compounds tanzawaic acid B (3) and trichodermamide C (4) by physicochemical (PC...

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Mar. Drugs - ISSN 1660-3397