Special Issue "Marine Molecules for the Treatment of Thrombosis"
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (31 August 2020).
Interests: drug delivery; tissue engineering; polysaccharide; chitosan; hybrid; pegylation; oxime click; proteoglycan; glycosaminoglycan; gel permeation chromatography; NMR relaxation
According to the World Health Organization, the formation of thrombi is one of the leading causes of death in modern life. Current antithrombotic treatments suffer from potential secondary effects or increase the health care costs because of a necessary control of the coagulation levels for vitamin k antagonists or of the high production costs for recent synthetic thrombin and factor Xa inhibitors. For this reasons, marine molecules are being thoughtfully screened for anticoagulants. The best known marine anticoagulants are sulphated polysaccharides: fucoidans and carrageenans from algae; fucosylated chondroitin sulphates, sulfated fucans, and galactans from algae, ascidians, sea cucumbers, and urchins; heparins and heparan sulfate hybrids found in molluscs, crustacean, ascidians, and sea urchins. However, other less renowned marine molecules present interesting prospects: anticoagulant peptides (from blood-sucking worms and bacteria and sponges), fibrinolytic enzymes (from algae and bacteria), anticoagulant terpenes and sphingosines (from algae and sponges). The aim of this Special Issue is to recapitulate the current knowledge and publish novel articles on marine antithrombotic molecules.
Dr. Ramon Novoa Carballal
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Thrombin inhibitor
- Factor Xa inhibitors
- Vitamin k antagonists
- Sulphated polysaccharides
- Sulphated Glycosaminoglycans
- fucosylated chondroitin
- sulphates and galactans
- Sulfated fucans and galactans
- Anticoagulant peptides