Molecules, Volume 30, Issue 18

Understanding the non-equilibrium dynamical processes in two-dimensional (2D) transition metal dichalcogenide (TMDC) heterostructures is essential for elucidating their photoelectric behaviors. In this work, we investigate the electronic structure, e...

Muscle atrophy is defined as reductions in muscle size and function and represents a critical concern affecting elderly populations, immobilized patients, and individuals following specific dietary regimens, such as fasting and low-protein diets. Thi...

The Signal Amplification By Reversible Exchange (SABRE) technique provides enhancement of Nuclear Magnetic Resonance (NMR) signals up to several orders of magnitude using chemical exchange of a substrate and parahydrogen on an iridium complex. Theref...

We describe the first solid-phase synthesis of thiazolo [4,5-d] [1,2,3] triazin-4(3H)-one derivatives using Merrifield resin. The modular sequence involves Thorpe–Ziegler cyclization, sulfone oxidation, and disulfonate nucleophilic substitution...

Despite its many important health benefits, fish consumption is associated with a growing risk of toxicity due to increasing levels of environmental pollution. Therefore, this study compared the potential risks to human health associated with the con...

Amitriptyline (AMT), a widely prescribed antidepressant, and its metabolites have emerged as significant environmental contaminants, posing substantial risks to aquatic organisms and human health. Systematic and in-depth investigations into advanced...

In the published paper [...]

Exposure to sunlight, whose main component is UV radiation (UVR), leads to various skin damage such as sunburns, premature aging, or more severe issues such as increased symptoms of autoimmune disease and skin cancer. Therefore, there is a growing in...

Carbon dioxide (CO₂) capture using alkanolamines remains the most mature technology, yet faces challenges including solvent loss, high regeneration energy and equipment corrosion. Ionic liquids (ILs) are proposed as alternatives, but their high visco...

Lubricating oil plays a critical role in protecting mechanical systems. Driven by sustainable development strategies, the development of high-performance, biocompatible green lubricants has become an urgent industry need. Biomass resources, character...

Morinda citrifolia L., known as noni, is a tropical plant belonging to the Rubiaceae family and is widely used in traditional medicine for its therapeutic properties. This review compiles botanical, ethnomedicinal, phytochemical, and pharmacological...

Olive leaves, a significant source of agri-food waste, can be valorized as feedstock in biorefineries due to their high content of antioxidant compounds, mainly polyphenols. This study aims to valorize olive leaves through an efficient solid/liquid e...

Neuroendocrine neoplasms (NENs) represent a small and heterogeneous group of tumors that share a common phenotype, originating from cells within the endocrine and nervous systems. Metallodrugs have had a significant impact on the treatment of NENs, a...

This study compared the yield, percentage solids, electrophoretic profile, gelatinolytic activity, and brine shrimp lethality of Bitis arietans venom prepared using freeze-drying and desiccator drying. Bitis arietans venom was collected from snakes a...

The main objective of the study was to choose the best salicylic acid-based monomers through in silico research to improve the antibacterial effects of dental prostheses, refine the synthesis process of such monomers, and examine their antibacterial...

Neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease, multiple sclerosis, and Huntington’s disease, represent unmet medical and social needs. Still, no definitive cure exists for these illnesses, hence a th...

Amoxicillin is widely prescribed, either as a monotherapy or in combination with clavulanic acid, with its therapeutic indications including a broad range of infections. Its combination with clavulanic acid maintains its known activity against strain...

Copper is an important environmental pollutant that poses a significant threat to human health and environmental safety. Therefore, the development of methods for detecting Cu²⁺ is of great significance. A novel fluorometric/colorimetric dual-mode se...

Photocatalytic hydrogen evolution from water is a sustainable approach to producing clean energy and promoting sustainable development. However, the low efficiency of photocatalysts under visible light and even near-infrared irradiation remains the c...

Sirtuin 5 is an NAD⁺-dependent lysine deacylase that is involved in various biological processes and has emerged as a promising target for pharmaceutical therapies. The development of highly potent and subtype-selective sirtuin 5 inhibitors for their...

In this study, we investigated the influence of polymer nature and support characteristics on the performance of Pd-based heterogeneous catalysts. Catalysts were prepared via sequential adsorption of poly(4-vinylpyridine) (P4VP) or chitosan (CS) and...

In this study, the contents of minerals, free amino acids (FAAs), biogenic amines (BAs), γ-aminobutyric acid (GABA), and spermidine (SPD) were analyzed in selected white mold-ripened and blue-veined cheeses, including their spatial distribution...

In this work, we report optical and photoelectrochemical properties of BiVO₄ synthesized by microwave, sonochemical, sol–gel, and direct deposition on conductive substrate methods. Structural and morphological characterization using XRD, SEM, a...

This study highlights the use of alkyl polyglucosides (APGs) as sustainable and mild surfactants in cosmetic preparations, such as shampoos, following the principles of green chemistry and environmentally friendly development. APGs are non-ionic surf...

Garcinia kola is an emblematic tree used in traditional medicine in many regions in Africa. In particular, its nuts are commonly used for the management of various diseases. However, to the best of our knowledge, G. kola nuts have never been investig...

Tomato (Solanum lycopersicum) is an essential crop worldwide, yet it remains highly vulnerable to severe fungal and bacterial diseases. Traditional chemical-based disease management strategies, aimed at controlling these diseases face increasing scru...

Chitosan is considered an excellent biomaterial for epithelial healing treatment. However, information on its molecular interaction with cells at a molecular level is still lacking. Thus, in the present study, homemade synthesized chitosan nanopartic...

Insomnia is a common and complex disorder, rooted in the dysregulation of circadian rhythms, impaired neurotransmitter function, and disturbances in sleep–wake homeostasis. While conventional hypnotics such as benzodiazepines and Z-drugs are ef...

Activated carbon F-400 was modified by using different oxidation agents: nitric acid, sulfuric acid, and ozone. The influence of the type of carbon surface groups on adsorption effectiveness towards selected aromatic compounds was analyzed. The comme...

Metal–organic frameworks (MOFs) are materials with extremely valuable properties. The latter depend largely on the ligand used; therefore, the design of new organic linkers is a priority task today. A series of s-triazines possessing variable h...

Arnica montana L. (mountain arnica) is a medicinal plant with diverse biological activities commonly used in pharmacy and cosmetics. The attributes of A. montana are related to e.g., the concentration and chemical composition of its essential oils (E...

The prevalence of Ulcerative Colitis (UC) is continuously increasing globally, demanding the urgent search for new treatment agents due to the limitations of existing therapies. Premna puberula Pamp. (PP), a traditional medicinal and dietary plant, h...

Vegetarians must rely on supplements to meet the recommended daily intake of vitamin B12. Therefore, it is essential to establish a rapid, inexpensive, and reliable method of determining B12 levels in order to accurately characterize and assess the q...

It was previously demonstrated that timolol (TIM), naphazoline (NAPH), and diflunisal (DIF) are susceptible to degradation when exposed to extreme pH conditions and UV/Vis light. However, their stability in the presence of pharmaceutical excipients r...

This study investigates the influence of pectin and copper incorporation on the catalytic properties of Pd/ZnO catalysts in the liquid-phase hydrogenation of 2-hexyn-1-ol and photocatalytic hydrogen evolution. A series of monometallic Pd/ZnO catalyst...

Rosa canina L. powders are rich in bioactive compounds; however, thermal processing and carrier addition can markedly alter their composition, affecting nutritional quality, safety and potential health effects. This study assessed the impact of juice...

This study reports the production of carbon adsorbents via microwave-assisted chemical activation of caraway seeds using potassium carbonate (K₂CO₃). Microwave irradiation enables rapid, energy-efficient heating, promoting effective pore development...

Sinomenine has long been known as an anti-inflammatory drug, while poor efficiency and large-dose treatment had limited its further application. Five novel sinomenine 1-Br-4-cinnamic acid esters derivatives 2a–2e were designed and synthesized t...

In this study, a commercial anion-exchange resin (D301), known for high regenerability but limited selectivity, was chemically modified to enhance its sorption performance. The modification included graft polymerization of glycidyl methacrylate follo...

Phase molybdenum disulfide (1T-MoS₂) holds significant promise as an anode material for sodium-ion batteries (SIBs) due to its metallic conductivity and expanded interlayer distance. However, the practical application of 1T-MoS₂ is hindered by its in...

This review discusses the development of small-diameter silk-based vascular grafts, based on insights obtained through solid-state NMR structural analysis. With the increasing prevalence of cardiovascular diseases, the demand for vascular grafts with...

Given the pivotal role of coumarins as tunable nonlinear optical (NLO) materials for advanced photonics, this study aims to decipher the regulatory mechanisms governing their excited-state dynamics and nonlinear absorption. In this study, two amino-c...

Zeolites are widely used as solid acid catalysts and also as supports in complex multifunctional heterogeneous systems. In recent years, there has been an increase in the development of zeolite-based catalysts with hierarchical porosity combined with...

Theophylline represents a significant public health challenge due to its dual acute and chronic toxicity resulting from therapeutic, environmental, and dietary exposures. Effective monitoring across the bio-environmental–food triad requires ana...

Magnetic nanoparticles (MNPs) of iron oxide are becoming increasingly popular due to their excellent physicochemical properties as well as very good adsorption and catalytic properties towards heavy metal ions (HMIs). They are used in many industries...

Chili peppers (Capsicum spp.), cacao (Theobroma cacao L.), and coffee (Coffea spp.) are important crops worldwide. Nearly 35%, 80%, and 45% of the respective fruits are underutilized or discarded, representing a considerable economic loss. This work...

(+)-Isocampholenic acid, prepared in two steps from (1S)-(+)-10-camphorsulfonic acid in 60% yield (on a scale of 172 mmol), served as the starting compound for the synthesis of small libraries of isocampholenic acid derivatives, comprising a total of...

A new synthetic strategy for pyrazolo[1,5-d][1,2,4]triazin-7(6H)-ones 4 through intramolecular cyclization of alkyl 2-(4-nitro-1H-pyrazol-3-yl)methylene)hydrazine-1-carboxylates 3 is described, allowing us to selectively modify the N-substituent in 3...

Bicalutamide (BCL), a clinically important non-steroidal antiandrogen, exhibits pronounced conformational polymorphism and complex solid-state behaviour that critically influence its physicochemical and biopharmaceutical properties. This review compr...

Non-alcoholic fatty liver disease (NAFLD) is among the most prevalent liver disorders globally, affecting approximately 25% to 40% of the adult population. Closely associated with metabolic syndrome, obesity, insulin resistance, and dyslipidemia, NAF...