Analysis and Biological Evaluation of Bioactive Compounds from Natural Sources, 2nd Edition
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 1146
Special Issue Editors
Interests: natural product chemistry; chromatography; medicinal and pharmaceutical chemistry; nuclear magnetic resonance; antioxidant activity; antioxidants; bioactivity; herbal medicine; phytochemicals; phytochemical analysis
Special Issues, Collections and Topics in MDPI journals
2. Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, CT, Italy
Interests: cell culture; in vitro model; biological application of natural product; antioxidant activity; neuroinflammation; neurodegeneration; healing; skin protective activity; photoaging; apoptosis; oncogene; cell cycle; cytotoxic activity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Since ancient times, extracts from plants or other organisms have been used as remedies for the treatment of different types of diseases, and today, it is well known that their biological activities are imputable to active compounds that are present in their chemical composition. For this reason, significant efforts have been invested to delineate the chemical composition profile of these natural remedies, but only in recent times have their active ingredients been isolated and identified, with a final goal of verifying their chemotherapeutic potential.
From this area of research, the close relationship between the chemical composition—in terms of secondary metabolites—and the ability to play a role in health has emerged quite clearly; therefore, there are numerous multidisciplinary studies aimed at the chemical and biological evaluation of complex natural matrices.
In this context, there is renewed interest in bioactive natural products due to their high chemodiversity, which cannot be guaranteed with synthetic methods.
Today, it is also known that many of these natural molecules, which have conferred an 'evolutionary advantage' to the species of origin, have been used as lead compounds for the development of drugs that are used for medical purposes; for example, aspirin is a semi-synthetic and commonly used drug, obtained as an acetylated analogue of salicin, which is isolated from Salix alba.
On the other hand, scientific attention is focused on secondary metabolites, such as on the well-known polyphenols, with particular interest in those that are obtained from edible plants, to verify their role in the maintenance of good general health in the global population.
Due to the strong interest in this topic, in this Special Issue, we aim to collect original multidisciplinary research reports and updated literature reviews within several fields relating to the extraction, secondary metabolic profile characterization, bioactivity, and mechanisms of action of bioactive compounds from natural sources.
Dr. Luana Pulvirenti
Dr. Rosanna Avola
Guest Editors
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Keywords
- natural products
- natural product chemistry
- polyphenols
- vegetable extract profiling
- herbal medicine
- phytochemicals
- biological applications of natural products
- mechanism of action
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