Metal-Based Drugs: Past, Present and Future, 3rd Edition

Dear Colleagues,

The drug discovery process is a challenging multi-step progressuib towards the identification of potential new medicines. New drugs are needed to prevent a disease, to fight against a pathology, or to diagnose a medical condition when there are currently no suitable medical products. The pharmaceutical potential of metals and their derivatives has been recognized across very different cultures for millennia, and with the advent of modern medicine, several metal-based drugs have been approved as effective therapeutic tools in clinical treatment. Indeed, a large variety of metal compounds show significant bioactivity against a range of diseases. For instance, a number of metal complexes have been developed for the treatment/cure of a variety of disorders, such as diabetes, ulcers, inflammatory and cardiovascular diseases, cancers, and so on. The study of metal-based drugs represents an important part of modern bioinorganic chemistry. This Special Issue aims to provide a survey of the most recent studies concerning the computational drug discovery, design, synthesis, specific or non-specific carriers (nanoparticles, liposomes, cyclodextrins, etc.), characterization, mechanisms of action, pharmacokinetic studies, etc., of new metal drugs. In addition, studies concerning their in vivo/in vitro therapeutic properties, and therefore their possible use in the medical field, for the treatment of different diseases are of great interest.

This Special Issue will cover a selection of recent research and review articles in the field of metal-based drugs used in medicine. Studies on drugs without biological activity but that explore the potential for biological activity are also welcome. It is a pleasure to invite you to submit a manuscript to this Special Issue.

Prof. Dr. Roxana Liana Lucaciu
Prof. Dr. Adriana Corina Hangan
Guest Editors

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