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Molecules, Volume 29, Issue 7

2024 April-1 - 271 articles

Cover Story: Gas-phase ion chemistry can have relevant impacts on atmospheric processes, including cloud condensation nuclei formation influenced by cosmic rays. This study explores the relevant HO2 and protonated formaldehyde formation from methanol radical cation and oxygen following an exothermic ionic route. Experimental synchrotron studies reveal a rapid hydrogen transfer, and computational analysis elucidates reaction dynamics and kinetics, indicating rapid capture theory kinetics. This research deepens our understanding of atmospheric chemical reactions, emphasizing the role of ion-driven processes. View this paper
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Articles (271)

  • Article
  • Open Access
2 Citations
2,011 Views
13 Pages

Phenylspirodrimane with Moderate Reversal Effect of Multidrug Resistance Isolated from the Deep-Sea Fungus Stachybotrys sp. 3A00409

  • Xinhua Ma,
  • Min Wu,
  • Zhenwei Chen,
  • Fan Cao,
  • Tianhua Zhong,
  • Zhuhua Luo,
  • Zongze Shao,
  • Yonghong Zhang,
  • Limin Chen and
  • Zhiqiang Zhang

Two new phenylspirodrimanes, stachybotrins K and L (1 and 2), together with eight known analogues (310), were isolated from deep-sea-derived Stachybotrys sp. MCCC 3A00409. Their structures were determined by extensive NMR data and mass spectro...

  • Article
  • Open Access
7 Citations
2,298 Views
13 Pages

Facilitated Unidirectional Electron Transmission by Ru Nano Particulars Distribution on MXene Mo2C@g-C3N4 Heterostructures for Enhanced Photocatalytic H2 Evolution

  • Qiuyu Chen,
  • Zonghan Huang,
  • Meng Liu,
  • Xiaoping Li,
  • Yuxuan Du,
  • Xiaobao Chen,
  • Dahu Ding,
  • Shengjiong Yang,
  • Yang Chen and
  • Rongzhi Chen

Precious metals exhibit promising potential for the hydrogen evolution reaction (HER), but their limited abundance restricts widespread utilization. Loading precious metal nanoparticles (NPs) on 2D/2D heterojunctions has garnered considerable interes...

  • Review
  • Open Access
10 Citations
4,221 Views
21 Pages

New Avenues and Major Achievements in Phytocompounds Research for Glioblastoma Therapy

  • Aleksandra Majchrzak-Celińska and
  • Elżbieta Studzińska-Sroka

Phytocompounds have been evaluated for their anti-glioblastoma actions for decades, with promising results from preclinical studies but only limited translation into clinics. Indeed, by targeting multiple signaling pathways deregulated in cancer, the...

  • Article
  • Open Access
6 Citations
2,562 Views
15 Pages

Lipophilicity is one of the most important properties of compounds required to estimate the absorption, distribution, and transport in biological systems, in addition to solubility, stability, and acid–base nature. It is crucial in predicting t...

  • Article
  • Open Access
3 Citations
5,400 Views
19 Pages

Deacetylated Konjac Glucomannan with a Slower Hydration Rate Delays Rice Digestion and Weakens Appetite Response

  • Chenfeng Xu,
  • Kaixuan Cheng,
  • Yu Kang,
  • Chao Cheng,
  • Chi Zhang and
  • Longchen Shang

The physical characteristics of chyme during gastrointestinal digestion are considered to significantly affect nutrient digestion and absorption (such as glucose diffusion), which has an impact on postprandial satiety. The present study aims to analy...

  • Review
  • Open Access
8 Citations
3,153 Views
35 Pages

Metals are beneficial to life, but the presence of these elements in excessive amounts can harm both organisms and the environment; therefore, detecting the presence of metals is essential. Currently, metal detection methods employ powerful instrumen...

  • Article
  • Open Access
3 Citations
2,370 Views
18 Pages

To satisfy the needs of precision machining, ultrafine tungsten carbide (WC)-based cemented carbide with fine grain size and excellent mechanical properties was prepared. Ultrafine cemented carbide was prepared by spark plasma sintering (SPS) using W...

  • Article
  • Open Access
7 Citations
2,772 Views
10 Pages

This study evaluated the feasibility of contextually producing hydrogen, microbial proteins, and polyhydroxybutyrate (PHB) using a mixed culture of purple phototrophic bacteria biomass under photo fermentative conditions. To this end, three consecuti...

  • Article
  • Open Access
4 Citations
3,386 Views
13 Pages

Robust Thiazole-Linked Covalent Organic Frameworks for Water Sensing with High Selectivity and Sensitivity

  • Kewei Wang,
  • Zhaoxia Wu,
  • Na Ji,
  • Tingxia Wang,
  • Yongxin Gu,
  • Zhixiang Zhao,
  • Yong Guo,
  • Xiaoyan Wang,
  • Zhifang Jia and
  • Bien Tan

The rational design of covalent organic frameworks (COFs) with hydrochromic properties is of significant value because of the facile and rapid detection of water in diverse fields. In this report, we present a thiazole-linked COF (TZ-COF-6) sensor wi...

  • Article
  • Open Access
10 Citations
2,850 Views
14 Pages

Development of Paper-Based Fluorescent Molecularly Imprinted Polymer Sensor for Rapid Detection of Lumpy Skin Disease Virus

  • Samr Kassem,
  • Mervat E. Hamdy,
  • Karim M. Selim,
  • Dalia M. A. Elmasry,
  • Momtaz A. Shahein and
  • Dalia M. El-Husseini

Lumpy Skin Disease (LSD) is a notifiable viral disease caused by Lumpy Skin Disease virus (LSDV). It is usually associated with high economic losses, including a loss of productivity, infertility, and death. LSDV shares genetic and antigenic similari...

  • Article
  • Open Access
8 Citations
2,901 Views
15 Pages

Citrus limon Wastes from Part of the Eastern Cape Province in South Africa: Medicinal, Sustainable Agricultural, and Bio-Resource Potential

  • Phumelele Nodola,
  • Gugulethu M. Miya,
  • Vuyokazi Mazwi,
  • Ayodeji O. Oriola,
  • Opeoluwa O. Oyedeji,
  • Yiseyon S. Hosu,
  • Simon K. Kuria and
  • Adebola O. Oyedeji

The fruits of Citrus limon are often purchased for their vitamin C-rich juice, while the fruit peel and the tree leaves are discarded as wastes. This study obtained the chemical profiles of the essential oils (EOs) of C. limon wastes (the peel and le...

  • Review
  • Open Access
26 Citations
6,817 Views
26 Pages

Research Progress on the Combination of Quorum-Sensing Inhibitors and Antibiotics against Bacterial Resistance

  • Jiahao Wang,
  • Xingyue Lu,
  • Chenjie Wang,
  • Yujie Yue,
  • Bin Wei,
  • Huawei Zhang,
  • Hong Wang and
  • Jianwei Chen

Bacterial virulence factors and biofilm development can be controlled by the quorum-sensing (QS) system, which is also intimately linked to antibiotic resistance in bacteria. In previous studies, many researchers found that quorum-sensing inhibitors...

  • Article
  • Open Access
9 Citations
2,964 Views
14 Pages

Essential oils (EOs), including those from the Asteraceae plants, have been shown to have promising insecticidal activity against a wide range of insect pests. Understanding the mechanism of action of EOs is one of the studied aspects. The present st...

  • Article
  • Open Access
8 Citations
2,849 Views
17 Pages

Bicarbazole-Benzophenone Based Twisted Donor-Acceptor Derivatives as Potential Blue TADF Emitters for OLEDs

  • Iram Siddiqui,
  • Prakalp Gautam,
  • Dovydas Blazevicius,
  • Jayachandran Jayakumar,
  • Sushanta Lenka,
  • Daiva Tavgeniene,
  • Ernestas Zaleckas,
  • Saulius Grigalevicius and
  • Jwo-Huei Jou

Over the past few decades, organic light-emitting diodes (OLEDs) find applications in smartphones, televisions, and the automotive sector. However, this technology is still not perfect, and its application for lighting purposes has been slow. For fur...

  • Review
  • Open Access
7 Citations
3,088 Views
26 Pages

Structures and Dynamics of Complex Guest Molecules in Confinement, Revealed by Solid-State NMR, Molecular Dynamics, and Calorimetry

  • Nadia B. Haro Mares,
  • Sonja C. Döller,
  • Till Wissel,
  • Markus Hoffmann,
  • Michael Vogel and
  • Gerd Buntkowsky

This review gives an overview of current trends in the investigation of confined molecules such as water, small and higher alcohols, carbonic acids, ethylene glycol, and non-ionic surfactants, such as polyethylene glycol or Triton-X, as guest molecul...

  • Article
  • Open Access
2 Citations
1,818 Views
17 Pages

Olibanum is a resinous traditional Chinese medicine that is directly used as a powder. It is widely used in China and is often combined with other traditional Chinese medicine powders to promote blood circulation and relieve pain, as well as to treat...

  • Article
  • Open Access
1 Citations
2,257 Views
14 Pages

The Beckmann rearrangement of ketoximes to their corresponding amides, using a Brønsted acid-mediated fragmentation and migration sequence, has found wide-spread industrial application. We postulated that the development of a methodology to ac...

  • Article
  • Open Access
6 Citations
2,432 Views
13 Pages

The aqueous instability of halide perovskite seriously hinders its direct application in water as a potential photocatalyst. Here, we prepared a new type of polyvinylpyrrolidone (PVP) passivated δ-CsPbI3 (δ-CsPbI3@PVP) microcrystal by a f...

  • Article
  • Open Access
4 Citations
3,222 Views
23 Pages

Network Pharmacology Analysis of Liquid-Cultured Armillaria ostoyae Mycelial Metabolites and Their Molecular Mechanism of Action against Gastric Cancer

  • Zhishuo Wang,
  • Ruiqi Wang,
  • Zhiguo Na,
  • Shanshan Liang,
  • Fan Wu,
  • Hongyao Xie,
  • Xue Zhang,
  • Wei Xu and
  • Xin Wang

Armillaria sp. are traditional edible medicinal mushrooms with various health functions; however, the relationship between their composition and efficacy has not yet been determined. Here, the ethanol extract of liquid-cultured Armillaria ostoyae myc...

  • Feature Paper
  • Article
  • Open Access
1 Citations
2,744 Views
12 Pages

Porous aromatic frameworks (PAFs) are an auspicious class of materials that allow for the introduction of sulfonic acid groups at the aromatic core units by post-synthetic modification. This makes PAFs promising for proton-exchange materials. However...

  • Article
  • Open Access
7 Citations
2,688 Views
19 Pages

Characteristics of Dialdehyde Cellulose Nanofibrils Derived from Cotton Linter Fibers and Wood Fibers

  • Qiyuan Tu,
  • Wenhua Gao,
  • Junjie Zhou,
  • Jinglin Wu,
  • Jinsong Zeng,
  • Bin Wang and
  • Jun Xu

Two types of cellulose nanofibrils (CNFs) were isolated from cotton linter fibers and hardwood fibers through mechanical fibrillation methods. The dialdehyde cellulose nanofibrils (DACNFs) were prepared through the periodate oxidation method, and the...

  • Article
  • Open Access
11 Citations
2,920 Views
17 Pages

Luteolin-7-O-β-d-glucuronide Ameliorates Cerebral Ischemic Injury: Involvement of RIP3/MLKL Signaling Pathway

  • Xing Fan,
  • Fang Lin,
  • Yu Chen,
  • Yuling Dou,
  • Ting Li,
  • Xinxin Jin,
  • Jintao Song and
  • Fang Wang

Luteolin-7-O-β-d-glucuronide (LGU) is a major active flavonoid glycoside compound that is extracted from Ixeris sonchifolia (Bge.) Hance, and it is a Chinese medicinal herb mainly used for the treatment of coronary heart disease, angina pectoris...

  • Article
  • Open Access
4 Citations
2,432 Views
26 Pages

The Effect of Fermentation on the Chemical Constituents of Gastrodia Tuber Hallimasch Powder (GTHP) Estimated by UHPLC-Q-Orbitrap HRMS and HPLC

  • Yaning Wu,
  • Hongwei Zhang,
  • Jianguang Zhu,
  • Zhenling Zhang,
  • Songbo Ma,
  • Yongqi Zhao,
  • Yiming Wang,
  • Jun Yuan,
  • Xing Guo and
  • Shuai Zhang
  • + 1 author

Objective: To compare the effect of fermentation on the chemical constituents of Gastrodia Tuder Halimasch Powder (GTHP), to establish its fingerprinting and multicomponent content determination, and to provide a basis for the processing, handling, a...

  • Article
  • Open Access
19 Citations
3,098 Views
18 Pages

Fluorescence Detection of Pb2+ in Environmental Water Using Biomass Carbon Quantum Dots Modified with Acetamide-Glycolic Acid Deep Eutectic Solvent

  • Shiwen Xing,
  • Keyang Zheng,
  • Lei Shi,
  • Kaiming Kang,
  • Zhixiao Peng,
  • Xiaojie Zhang,
  • Baoyou Liu,
  • Huilong Yang and
  • Gang Yue

In this study, a novel green fluorescent probe material, nitrogen-doped carbon quantum dots (N-CQDs), was prepared by a one-step hydrothermal synthesis method using walnut green skin as a carbon source and acetamide-glycolic acid deep eutectic solven...

  • Article
  • Open Access
8 Citations
3,121 Views
16 Pages

Metabolic Characteristics and Discriminative Diagnosis of Growth Hormone Deficiency and Idiopathic Short Stature in Preadolescents and Adolescents

  • Yajie Chang,
  • Jing Chen,
  • Hongwei Zhu,
  • Rong Huang,
  • Jinxia Wu,
  • Yanyan Lin,
  • Quanquan Li,
  • Guiping Shen and
  • Jianghua Feng

Growth hormone deficiency (GHD) and idiopathic short stature (ISS) are the most common types of short stature (SS), but little is known about their pathogenesis, and even less is known about the study of adolescent SS. In this study, nuclear magnetic...

  • Article
  • Open Access
3 Citations
3,212 Views
16 Pages

Use of Residual Malt from an Artisanal Beer Brewing Process in the Biosynthesis of Silver Nanoparticles Mediated by Nucleating and Structure-Directing Agents

  • César A. Dueñas-Bolaños,
  • Margarita Cid-Hernández,
  • Gilberto Velázquez-Juárez,
  • Luis A. García-Casillas,
  • Luis J. González-Ortiz,
  • María Judith Sánchez-Peña,
  • Azucena Herrera-González,
  • Oscar Guillermo Zúñiga-González and
  • Edgar J. López-Naranjo

Biosynthesized silver nanoparticles (AgNPs) are widely used in varied applications, which are morphology dependent. Consequently, a morphology-controlled synthesis is mandatory. Although there are several studies focused on the plant extract-based bi...

  • Review
  • Open Access
11 Citations
7,399 Views
16 Pages

Curcumin (CCM) is a polyphenol compound extracted from the turmeric rhizome. It has various biological activities, including antibacterial, anti-inflammatory, anti-cancer, and antioxidant. Due to its diverse activities, it is often used by researcher...

  • Article
  • Open Access
6 Citations
3,394 Views
13 Pages

Fluorescent sensors with single reading are generally subject to unpredictable disturbs from environmental and artificial factors. In order to overcome this barrier of detection reliability, a paper-based optical sensor with proportional fluorescence...

  • Article
  • Open Access
18 Citations
5,495 Views
16 Pages

Highly Sensitive and Selective Toluene Gas Sensors Based on ZnO Nanoflowers Decorated with Bimetallic AuPt

  • Huiting Peng,
  • Yiping Liu,
  • Yinfeng Shen,
  • Ling Xu,
  • Jicun Lu,
  • Ming Li,
  • Hong-Liang Lu and
  • Liming Gao

Efficient sensors for toluene detecting are urgently needed to meet people’s growing demands for both environment and personal health. Metal oxide semiconductor (MOS)-based sensors have become brilliant candidates for the detection of toluene b...

  • Article
  • Open Access
4 Citations
1,931 Views
14 Pages

Immobilized metal ion affinity chromatography (IMAC) adsorbents generally have excellent affinity for histidine-rich proteins. However, the leaching of metal ions from the adsorbent usually affects its adsorption performance, which greatly affects th...

  • Article
  • Open Access
5 Citations
2,853 Views
14 Pages

Antimicrobial Activity and Phytochemical Characterization of Baccharis concava Pers., a Native Plant of the Central Chilean Coast

  • Maité Rodríguez-Díaz,
  • Fabián E. Pérez,
  • Paloma M. Manosalva,
  • Juan I. Cerda,
  • Consuelo F. Martínez-Contreras,
  • Aracely Y. Mora,
  • Nicolás A. Villagra,
  • Sergio A. Bucarey,
  • Andrés Barriga and
  • Alejandro A. Hidalgo
  • + 2 authors

Few sclerophyllous plants from the central coast of Chile have been systematically studied. This work describes the phytochemical composition and antimicrobial properties of Baccharis concava Pers. (sin. B. macraei), a shrub found in the first line a...

  • Review
  • Open Access
4 Citations
2,800 Views
20 Pages

Spirotryprostatin alkaloids, a class of alkaloids with a unique spirocyclic indoledionepiperazine structure, were first extracted from the fermentation broth of Aspergillus fumigatus and have garnered significant attention in the fields of biology an...

  • Article
  • Open Access
1,881 Views
9 Pages

Microplastics have garnered an infamous reputation as a sorbate for many concerning environmental pollutants and as a delivery vehicle for the aquatic food chain through the ingestion of these contaminated small particulates. While sorption mechanism...

  • Article
  • Open Access
22 Citations
2,811 Views
11 Pages

Low-dimensional metal halides with efficient luminescence properties have received widespread attention recently. However, nontoxic and stable low-dimensional metal halides with efficient blue emission are rarely reported. We used a solvothermal synt...

  • Article
  • Open Access
5 Citations
2,623 Views
14 Pages

The process of extracting polyphyllin II and polyphyllin VII by water-assisted extraction was established and optimized in this study. Response surface methodology was used to establish a prediction model to optimize the extraction conditions. Based...

  • Article
  • Open Access
8 Citations
3,877 Views
15 Pages

Enhanced Solubility of Ibuprofen by Complexation with β-Cyclodextrin and Citric Acid

  • Tsveta Sarafska,
  • Stanislava Ivanova,
  • Todor Dudev,
  • Christo Tzachev,
  • Vesselin Petrov and
  • Tony Spassov

The ability of β-CD to form inclusion complexes with ibuprofen (IBU) and at the same time to make a two-phase system with citric acid was explored in the present study for achieving improved solubility and dissolution rate of IBU. Mechanical mil...

  • Review
  • Open Access
6 Citations
3,198 Views
25 Pages

Diterpenes represent one of the most diverse and structurally complex families of natural products. Among the myriad of diterpenoids, grayanane diterpenes are particularly notable. These terpenes are characterized by their unique 5/7/6/5 tetracyclic...

  • Review
  • Open Access
4 Citations
3,420 Views
24 Pages

Research Progress on Sesquiterpene Compounds from Artabotrys Plants of Annonaceae

  • Yupei Sun,
  • Jianzeng Xin,
  • Yaxi Xu,
  • Xuyan Wang,
  • Feng Zhao,
  • Changshan Niu and
  • Sheng Liu

Artabotrys, a pivotal genus within the Annonaceae family, is renowned for its extensive biological significance and medicinal potential. The genus’s sesquiterpene compounds have attracted considerable interest from the scientific community due...

  • Article
  • Open Access
3 Citations
2,514 Views
26 Pages

Synthesis of 4′-Thionucleoside Analogues Bearing a C2′ Stereogenic All-Carbon Quaternary Center

  • Carla Eymard,
  • Amarender Manchoju,
  • Abir Almazloum,
  • Starr Dostie,
  • Michel Prévost,
  • Mona Nemer and
  • Yvan Guindon

The design of novel 4′-thionucleoside analogues bearing a C2′ stereogenic all-carbon quaternary center is described. The synthesis involves a highly diastereoselective Mukaiyama aldol reaction, and a diastereoselective radical-based vinyl...

  • Article
  • Open Access
4 Citations
3,391 Views
15 Pages

Breast cancer stands as the most prevalent type of tumor and a significant contributor to cancer-related deaths. Among its various subtypes, triple-negative breast cancer (TNBC) presents the worst prognosis due to its aggressive nature and the absenc...

  • Article
  • Open Access
4 Citations
2,677 Views
14 Pages

Antibiotics in animal production are widely used around the world for therapeutic and preventive purposes, and in some countries, they still serve as antibiotic growth stimulants. Regardless of the purpose of using antibiotics in livestock, they may...

  • Article
  • Open Access
2 Citations
2,055 Views
15 Pages

Decades of research have illuminated the significant roles of gold/gold oxide clusters in small molecule catalytic oxidation. However, many fundamental questions, such as the actual sites to adsorb and activate O2 and the impact of charge, remain una...

  • Article
  • Open Access
8 Citations
2,770 Views
19 Pages

Physicochemical Characterization, Antioxidant, and Proliferative Activity of Colombian Propolis Extracts: A Comparative Study

  • Diana Marcela Buitrago,
  • Sandra J. Perdomo,
  • Francisco Arturo Silva,
  • Willy Cely-Veloza and
  • Gloria Inés Lafaurie

Propolis extracts have been widely studied due to their popularity in traditional medicine, presenting incredible biodiversity. This study aimed to analyze propolis extracts’ phytochemical, physicochemical, and biological activities from four d...

  • Article
  • Open Access
5 Citations
3,311 Views
14 Pages

Pregnant women must be wary of using traditional medicines due to the possibility of their having oxytoxic effects. Indonesia is rich in plants containing antioxidants. One of these plants is Phyllanthus emblica L. This study aims to determine the ph...

  • Article
  • Open Access
4 Citations
1,791 Views
11 Pages

Triterpenoids from the Leaves of Diospyros digyna and Their PTP1B Inhibitory Activity

  • Lan Huang,
  • Ziqi Wang,
  • Fangxin Wang,
  • Song Wang,
  • Dezhi Wang,
  • Meihua Gao,
  • Hua Li,
  • Min Song and
  • Xiaoqi Zhang

Six new 2α-hydroxy ursane triterpenoids, 3α-cis-p-coumaroyloxy-2α,19α-dihydroxy-12-ursen-28-oic acid (1), 3α-trans-p-coumaroyloxy-2α,19α-dihydroxy-12-ursen-28-oic acid (2), 3α-trans-p-coumaroyloxy-2&alp...

  • Review
  • Open Access
10 Citations
3,179 Views
18 Pages

A Review on the Design of Carbon-Based Nanomaterials as MRI Contrast Agents

  • Sarah Garifo,
  • Thomas Vangijzegem,
  • Dimitri Stanicki and
  • Sophie Laurent

The administration of magnetic resonance imaging (MRI) contrast agents (CAs) has been conducted since 1988 by clinicians to enhance the clarity and interpretability of MR images. CAs based on gadolinium chelates are the clinical standard used worldwi...

  • Article
  • Open Access
6 Citations
3,252 Views
19 Pages

Fever is a serious condition that can lead to various consequences ranging from prolonged illness to death. Tetrastigma hemsleyanum Diels et Gilg (T. hemsleyanum) has been used for centuries to treat fever, but the specific chemicals responsible for...

  • Article
  • Open Access
9 Citations
3,819 Views
13 Pages

The increasing global market size of high-energy storage devices due to the boom in electric vehicles and portable electronics has caused the battery industry to produce a lot of waste lithium-ion batteries. The liberation and de-agglomeration of cat...

  • Article
  • Open Access
2 Citations
3,250 Views
16 Pages

This study reports on a metal-free Covalent Triazine Framework (CTF) incorporating bithiophene structural units (TP-CTF) with a semicrystalline structure as an efficient heterogeneous photocatalyst under visible light irradiation. The physico-chemica...

  • Communication
  • Open Access
2 Citations
3,393 Views
9 Pages

Comparative Performance Assessment of Novel Fluorescence Immunoassay POCTs for Measuring Circulating Levels of Vitamin-D

  • Alice Palermiti,
  • Alessandra Manca,
  • Fabrizio Mastrantonio,
  • Domenico Maiese,
  • Aurora Curatolo,
  • Miriam Antonucci,
  • Marco Simiele,
  • Amedeo De Nicolò and
  • Antonio D’Avolio

Vitamin D (Vit D) is a fat-soluble molecule acting like a hormone, and it is involved in several biological mechanisms such as gene expression, calcium homeostasis, bone metabolism, immune modulation, viral protection, and neuromuscular functions. Vi...

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Molecules - ISSN 1420-3049