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19 Results Found

  • Article
  • Open Access
70 Citations
9,601 Views
13 Pages

14 August 2015

Antimicrobial peptides (AMPs) represent a diverse group of biologically active molecules that are part of the innate immune systems of a variety of organisms. Their primary function consists of protecting the host organism against invading microorgan...

(This article belongs to the Special Issue Proceedings of the the 4th Young Researcher Meeting, Münster, March 13-14, 2015)
  • Article
  • Open Access
38 Citations
4,423 Views
16 Pages

The Cysteine-Rich Peptide Snakin-2 Negatively Regulates Tubers Sprouting through Modulating Lignin Biosynthesis and H2O2 Accumulation in Potato

  • Mengsheng Deng,
  • Jie Peng,
  • Jie Zhang,
  • Shuang Ran,
  • Chengcheng Cai,
  • Liping Yu,
  • Su Ni,
  • Xueli Huang,
  • Liqin Li and
  • Xiyao Wang

25 February 2021

Potato tuber dormancy is critical for the post-harvest quality. Snakin/Gibberellic Acid Stimulated in Arabidopsis (GASA) family genes are involved in the plants’ defense against pathogens and in growth and development, but the effect of Snakin-2 (SN2...

(This article belongs to the Special Issue Fruit Physiology through Signaling Processes: Latest Advances and Future Challenges)
  • Review
  • Open Access
66 Citations
5,715 Views
17 Pages

12 October 2020

Plant host defense peptides (HDPs), also known as antimicrobial peptides (AMPs), are regarded as one of the most prevalent barriers elaborated by plants to combat various infective agents. Among the multiple classes of HDPs, the Snakin class attracts...

(This article belongs to the Special Issue Antifungal Peptides 2020)
  • Article
  • Open Access
3 Citations
1,895 Views
15 Pages

The Stylo Cysteine-Rich Peptide SgSnakin1 Is Involved in Aluminum Tolerance through Enhancing Reactive Oxygen Species Scavenging

  • Xueqiong Guo,
  • Shengnan Zhu,
  • Yingbin Xue,
  • Yan Lin,
  • Jingying Mao,
  • Shuyue Li,
  • Cuiyue Liang,
  • Xing Lu and
  • Jiang Tian

Stylo (Stylosanthes spp.) is an important pasture legume with strong aluminum (Al) resistance. However, the molecular mechanisms underlying its Al tolerance remain fragmentary. Due to the incomplete genome sequence information of stylo, we first cond...

(This article belongs to the Special Issue Plant Responses to Heavy Metals: From Deficiency to Excess)
  • Article
  • Open Access
18 Citations
3,634 Views
21 Pages

Genome-Wide Identification and Bioinformatics Analyses of Host Defense Peptides Snakin/GASA in Mangrove Plants

  • Chenjing Shang,
  • Ting Ye,
  • Qiao Zhou,
  • Pengyu Chen,
  • Xiangyu Li,
  • Wenyi Li,
  • Si Chen,
  • Zhangli Hu and
  • Wei Zhang

16 April 2023

Host defense peptides (HDPs) are components of plant defensive barriers that resist microbial infection. Members of the Snakin/GASA protein family in plants have functions of regulating plant growth, defense, and bacteriostasis. Most mangrove plants...

(This article belongs to the Section Microbial Genetics and Genomics)
  • Review
  • Open Access
705 Views
18 Pages

Antibiotic resistance has become a significant challenge for global health. Exploring novel antimicrobial compounds as alternatives to antibiotics is increasingly prominent in combating resistant pathogens. Antimicrobial peptides (AMPs), produced by...

(This article belongs to the Section Natural Products)
  • Article
  • Open Access
13 Citations
3,609 Views
9 Pages

Antifungal Activity of Avocado Seed Recombinant GASA/Snakin PaSn

  • Marco Antonio Hernández-Martínez,
  • Luis María Suárez-Rodríguez,
  • Joel Edmundo López-Meza,
  • Alejandra Ochoa-Zarzosa,
  • Rafael Salgado-Garciglia,
  • Silvia Patricia Fernández-Pavia and
  • Rodolfo López-Gómez

5 November 2022

The avocado fruit (Persea americana) has become a significant fruit in the human diet for its nutritional properties. However, the seed is a source of bioactive molecules and has been poorly utilized. Previously, we reported that the PaSn gene is exp...

(This article belongs to the Special Issue Antimicrobial Peptides from Natural Sources to Synthetic Optimization)
  • Article
  • Open Access
271 Views
31 Pages

16 September 2026

Background/Objectives: Antimicrobial peptides (AMPs) contribute to plant innate immunity and abiotic-stress adaptation, but their repertoires remain poorly characterized in extremophytic plants. We aimed to define AMP gene families and their expressi...

(This article belongs to the Section Plant Genetics and Genomics)
  • Article
  • Open Access
34 Citations
7,270 Views
16 Pages

15 September 2017

Antimicrobial peptides (AMPs) are small defense proteins present in various organisms. Major groups of AMPs include beta-barrelin, hevein, knottin, lipid transfer protein (LTP), thionin, defensin, snakin, and cyclotide. Most plant AMPs involve host p...

(This article belongs to the Special Issue Plant Defense Genes Against Biotic Stresses)
  • Article
  • Open Access
2 Citations
1,752 Views
31 Pages

Pangenomic Approach for the Identification and Functional Characterization of Active GASA Antimicrobial Genes in Citrus Rootstocks for Resistance Breeding Against Bacterial Pathogens

  • Florencia Nicole Bekier,
  • Mariana Conte,
  • Rodrigo Machado,
  • Lourdes Pereyra Ghidela,
  • Natalia Inés Almasia,
  • Vanesa Nahirñak,
  • Nadia Frías,
  • Paula del Carmen Fernández,
  • Cecilia Vazquez Rovere and
  • Gabriela Conti
  • + 1 author

30 January 2026

The SNAKIN/GASA family comprises antimicrobial peptides with proven activity against bacteria and fungi, making them promising candidates for improving disease resistance in citrus rootstocks. In sixty-seven new GASA variants from a citrus germplasm...

(This article belongs to the Section Plant Genetics, Genomics and Biotechnology)
  • Article
  • Open Access
15 Citations
3,348 Views
14 Pages

Assessment of the Cadmium and Copper Phytoremediation Potential of the Lobularia maritima Thioredoxin 2 Gene Using Genetically Engineered Tobacco

  • Rania Ben Saad,
  • Walid Ben Romdhane,
  • Narjes Baazaoui,
  • Mohamed Taieb Bouteraa,
  • Anis Ben Hsouna,
  • Avinash Mishra and
  • Sanja Ćavar Zeljković

30 January 2023

Rapid global modernization, urbanization, and industrialization have accelerated the release of heavy metals, causing soil pollution. These highly noxious environmental pollutants induce oxidative stress in plants via stimulation of the production of...

  • Article
  • Open Access
5 Citations
1,558 Views
15 Pages

StTCTP Positively Regulates StSN2 to Enhance Drought Stress Tolerance in Potato by Scavenging Reactive Oxygen Species

  • Shifeng Liu,
  • Feng Zhang,
  • Haojie Feng,
  • Xiyao Wang,
  • Qiang Wang,
  • Xianjun Lai and
  • Lang Yan

Drought is a negative agronomic effect that can lead to an increase in reactive oxygen species (ROS) levels. Excessive drought can severely alter cell membrane fluidity and permeability, significantly reducing cell viability. The Gibberellic acid-sti...

(This article belongs to the Special Issue Plant Response to Drought, Heat, and Light Stress)
  • Article
  • Open Access
8 Citations
4,459 Views
14 Pages

Mass Spectrometric Identification of Antimicrobial Peptides from Medicinal Seeds

  • Tessa B. Moyer,
  • Amanda M. Brechbill and
  • Leslie M. Hicks

1 December 2021

Traditional medicinal plants contain a variety of bioactive natural products including cysteine-rich (Cys-rich) antimicrobial peptides (AMPs). Cys-rich AMPs are often crosslinked by multiple disulfide bonds which increase their resistance to chemical...

(This article belongs to the Section Natural Products Chemistry)
  • Article
  • Open Access
16 Citations
4,236 Views
17 Pages

Synthetic Oligopeptides Mimicking γ-Core Regions of Cysteine-Rich Peptides of Solanum lycopersicum Possess Antimicrobial Activity against Human and Plant Pathogens

  • Marina P. Slezina,
  • Ekaterina A. Istomina,
  • Ekaterina V. Kulakovskaya,
  • Tatiana N. Abashina and
  • Tatyana I. Odintsova

24 September 2021

Plant cysteine-rich peptides (CRPs) represent a diverse group of molecules involved in different aspects of plant physiology. Antimicrobial peptides, which directly suppress the growth of pathogens, are regarded as promising templates for the develop...

(This article belongs to the Collection Feature Papers in Current Issues in Molecular Biology)
  • Review
  • Open Access
459 Citations
32,270 Views
47 Pages

Antimicrobial Peptides from Plants

  • James P. Tam,
  • Shujing Wang,
  • Ka H. Wong and
  • Wei Liang Tan

16 November 2015

Plant antimicrobial peptides (AMPs) have evolved differently from AMPs from other life forms. They are generally rich in cysteine residues which form multiple disulfides. In turn, the disulfides cross-braced plant AMPs as cystine-rich peptides to con...

(This article belongs to the Special Issue Identification and Characterization of Antimicrobial Peptides with Therapeutic Potential)
  • Article
  • Open Access
22 Citations
5,546 Views
27 Pages

Molecular Insights into the Role of Cysteine-Rich Peptides in Induced Resistance to Fusarium oxysporum Infection in Tomato Based on Transcriptome Profiling

  • Marina P. Slezina,
  • Ekaterina A. Istomina,
  • Tatyana V. Korostyleva,
  • Alexey S. Kovtun,
  • Artem S. Kasianov,
  • Alexey A. Konopkin,
  • Larisa A. Shcherbakova and
  • Tatyana I. Odintsova

Cysteine-rich peptides (CRPs) play an important role in plant physiology. However, their role in resistance induced by biogenic elicitors remains poorly understood. Using whole-genome transcriptome sequencing and our CRP search algorithm, we analyzed...

(This article belongs to the Special Issue Plant Innate Immunity 4.0)
  • Article
  • Open Access
2 Citations
1,351 Views
24 Pages

Broad-Spectrum Antimicrobial Potential of the γ-Core Motif Peptides of Filipendula ulmaria for Practical Applications in Agriculture and Medicine

  • Marina P. Slezina,
  • Ekaterina V. Kulakovskaya,
  • Ekaterina A. Istomina,
  • Tatiana N. Abashina and
  • Tatyana I. Odintsova

18 August 2025

Antimicrobial peptides (AMPs) are the promising candidates for the development of next-generation antimicrobials for agriculture and medicine; however, their large-scale production is costly. The γ-core motif peptides, functionally significant...

(This article belongs to the Special Issue Current Trends and Future Directions in Antimicrobial Peptide Research)
  • Article
  • Open Access
4 Citations
2,047 Views
17 Pages

Functional Analysis of Durum Wheat GASA1 Protein as a Biotechnological Alternative Against Plant Fungal Pathogens and a Positive Regulator of Biotic Stress Defense

  • Mohamed Taieb Bouteraa,
  • Walid Ben Romdhane,
  • Alina Wiszniewska,
  • Narjes Baazaoui,
  • Mohammad Y. Alfaifi,
  • Anis Ben Hsouna,
  • Miroslava Kačániová,
  • Stefania Garzoli and
  • Rania Ben Saad

2 January 2025

Plants are frequently challenged by a variety of microorganisms. To protect themselves against harmful invaders, they have evolved highly effective defense mechanisms, including the synthesis of numerous types of antimicrobial peptides (AMPs). Snakin...

(This article belongs to the Special Issue Biochemical Defenses of Plants)
  • Review
  • Open Access
922 Views
32 Pages

Cutaneous infections and chronic inflammatory wounds remain difficult to treat because antimicrobial resistance, polymicrobial biofilms, excessive protease activity, oxidative stress, and impaired barrier repair collectively reduce the effectiveness...

(This article belongs to the Section Drug Delivery and Controlled Release)