Skip Content
You are currently on the new version of our website. Access the old version .

21 Results Found

  • Review
  • Open Access
6 Citations
25,399 Views
25 Pages

Natural Products with Potential Effects on Hemorrhoids: A Review

  • Yicheng Liang,
  • Tankun Ren,
  • Ruyi Li,
  • Zhonghui Yu,
  • Yu Wang,
  • Xin Zhang,
  • Zonglin Qin,
  • Jinlong Li,
  • Jing Hu and
  • Chuanhong Luo

Hemorrhoid disease is a common anorectal disorder affecting populations worldwide, with high prevalence, treatment difficulties, and considerable treatment costs. Compared to other treatment options, medical therapy for hemorrhoids offers minimal har...

  • Review
  • Open Access
3 Citations
10,098 Views
21 Pages

Improving Hemorrhoid Outcomes: A Narrative Review and Best Practices Guide for Pharmacists

  • Nardine Nakhla,
  • Ashok Hospattankar,
  • Kamran Siddiqui and
  • Mary Barna Bridgeman

30 July 2025

Hemorrhoidal disease remains a prevalent yet often overlooked condition, affecting millions worldwide and imposing a substantial healthcare burden. Despite the availability of multiple treatment options, gaps persist in patient education, early sympt...

  • Article
  • Open Access
1,768 Views
6 Pages

Utilization of a Combined Procedure for Hemorrhoids and Chronic Anal Fissure Is Safe and Feasible

  • Rachel Gefen,
  • Adham Handal,
  • Carmel Ben-Ezra,
  • Shani Y. Parnasa,
  • Ido Mizrahi,
  • Mahmoud Abu-Gazala,
  • Alon J. Pikarsky and
  • Noam Shussman

Background: Hemorrhoids and anal fissure are among the most common benign anorectal conditions. The incidence of synchronous symptomatic hemorrhoids and chronic anal fissure is unknown. In this study we evaluated the outcomes of our experience with c...

  • Article
  • Open Access
10 Citations
3,109 Views
9 Pages

The Emborrhoid Technique for Treatment of Bleeding Hemorrhoids in Patients with High Surgical Risk

  • Paola Campennì,
  • Roberto Iezzi,
  • Angelo Alessandro Marra,
  • Alessandro Posa,
  • Angelo Parello,
  • Francesco Litta,
  • Veronica De Simone and
  • Carlo Ratto

21 September 2022

The Emborrhoid is an innovative non-surgical technique for the treatment of severe hemorrhoidal bleeding. Patient selection and the impact on quality of life have not been fully investigated. This prospective observational study aims to evaluate the...

  • Article
  • Open Access
4 Citations
11,013 Views
19 Pages

Anti-Inflammatory, Antimicrobial, and Vasoconstriction Activities of an Anti-Hemorrhoidal Mixture of Alchemilla vulgaris, Conyza bonariensis, and Nigella sativa: In Vitro and Clinical Evaluations

  • Omar Said,
  • Iyad Khamaysi,
  • Abdalsalam Kmail,
  • Omar Sadiq,
  • Besan Saied,
  • Stephen Fulder,
  • Basheer Abofarekh,
  • Mahmud Masalha,
  • Riyad Amin and
  • Bashar Saad

26 January 2022

Nigella sativa, Conyza bonariensis, and Alchemilla vulgaris are highly recommended in Greco-Arab traditional medicine as anti-hemorrhoid medicinal plants. The efficacy and safety of a topical cream (HPC) consisting of water–ethanol extracts of these...

  • Article
  • Open Access
6 Citations
3,347 Views
12 Pages

Safety and Effectiveness of a New Electrical Detachable Microcoil for Embolization of Hemorrhoidal Disease, November 2020–December 2021: Results of a Prospective Study

  • Miguel Angel De Gregorio,
  • Román Bernal,
  • Juan Jose Ciampi-Dopazo,
  • José Urbano,
  • Alfonso Millera and
  • José Andres Guirola

28 May 2022

Purpose: The purpose of this study was to prospectively evaluate the efficacy and safety of a new, bare platinum, detachable microcoil as a metallic embolization agent in the treatment of hemorrhoidal disease. Material and Methods: This prospective s...

  • Article
  • Open Access
1,351 Views
18 Pages

Barriers to Seeking Medical Care for Hemorrhoidal Symptoms: A Cross-Sectional Observational Study

  • Adrian Cote,
  • Roxana Loriana Negrut,
  • Bogdan Feder,
  • Ioan Andrei Antal,
  • Maur Sebastian Horgos,
  • Emilia Tomescu and
  • Adrian Marius Maghiar

29 July 2025

Background: Despite their high prevalence and potential for significant morbidity, hemorrhoidal symptoms remain underreported and undertreated. Misconceptions and stigma may delay care-seeking behaviors and negatively influence patient outcomes. Meth...

  • Article
  • Open Access
6 Citations
5,778 Views
10 Pages

A Prospective Study on the Efficacy of Two Different Phlebotonic Therapies as a Bridge to Surgery in Patients with Advanced Hemorrhoidal Disease

  • Raffaele Orefice,
  • Francesco Litta,
  • Angelo Parello,
  • Veronica De Simone,
  • Paola Campennì,
  • Angelo Alessandro Marra and
  • Carlo Ratto

7 April 2021

The aims of this study were to evaluate the efficacy of two different phlebotonic therapies, preoperatively administered in advanced hemorrhoidal disease (HD) patients with recommendation for surgery, and to assess patient satisfaction after treatmen...

  • Article
  • Open Access
14 Citations
5,445 Views
18 Pages

Preparation and In Vivo Evaluation of a Lidocaine Self-Nanoemulsifying Ointment with Glycerol Monostearate for Local Delivery

  • Ji-Hyun Kang,
  • Kwang-Hwi Yoo,
  • Hyo-Young Park,
  • Seung-Min Hyun,
  • Sang-Duk Han,
  • Dong-Wook Kim and
  • Chun-Woong Park

Lidocaine, a commonly used local anesthetic, has recently been developed into a number of ointment products to treat hemorrhoids. This study examined its efficient delivery to the dermis through the pharmaceutical improvement of hemorrhoid treatment...

  • Article
  • Open Access
1 Citations
3,870 Views
20 Pages

High-grade hemorrhoids are usually recommended to receive operational treatments. However, these traditional surgeries are associated with severe postoperative pain. A procedure for prolapse and hemorrhoids (PPH), a circular staple device, has been d...

  • Article
  • Open Access
2 Citations
3,414 Views
10 Pages

Prevalence of Obstructed Defecation among Patients Who Underwent Hemorrhoidectomy and Correlation between Preoperative Constipation Score and Postoperative Patients’ Satisfaction: A Prospective Study in Two Centers

  • Walid M. Abd El Maksoud,
  • Khaled S. Abbas,
  • Mohammed A. Bawahab,
  • Fares Rayzah,
  • Sultan M. Alkorbi,
  • Abdulelah G. Alfaifi,
  • Abdulrahman N. Alqahtani,
  • Abdullah F. Alahmari and
  • Turki B. Alotaibi

Background and Objectives: obstructed defecation syndrome (ODS) is a common but underestimated condition that may affect the outcomes after hemorrhoidectomy. Therefore, the aim of this study was to determine the prevalence of obstructed defecation sy...

  • Review
  • Open Access
12 Citations
4,405 Views
20 Pages

3 August 2022

Myrothamnus flabellifolius (Welw.) is used in African traditional medicine for the treatment of depression and mental disorder, asthma, infectious diseases, respiratory, inflammation, epilepsy, heart, wound, backaches, diabetes, kidney ailments, hype...

  • Abstract
  • Open Access
4,890 Views
2 Pages

The Importance of Rutin in Nutrition

  • Adna Salkić,
  • Lejla Mujezin,
  • Amela Džafić,
  • Zumreta Bihorac Kučuk and
  • Sanja Oručević Žuljević

Flavonoids are a group of natural compounds, the main nutritional ingredients of food of plant origin. Rutin is a flavonoid that is widely distributed in plants, fruits, and many foods. It is often called vitamin P or rutoside. According to its chemi...

  • Review
  • Open Access
1,889 Views
23 Pages

Current Insights into the Phytochemistry and Pharmacological Properties of Ruscus aculeatus

  • Wiktoria Pacuła,
  • Ireneusz Sowa,
  • Marcin Feldo,
  • Filip Graczyk,
  • Rafał Patryn and
  • Magdalena Wójciak

15 November 2025

Ruscus aculeatus L. (butcher’s broom), a member of the Asparagaceae family, is a perennial shrub native to the Mediterranean and Black Sea regions and naturalized in parts of Europe and North America. Traditionally, the rhizome and root of this...

  • Article
  • Open Access
1,310 Views
16 Pages

Laser Hemorrhoidoplasty: Postoperative Outcomes and Predictive Factors for Pain, Bleeding, and Recovery

  • Laurențiu Augustus Barbu,
  • Nicolae-Dragoș Mărgăritescu,
  • Liliana Cercelaru,
  • Tiberiu Stefăniță Țenea Cojan,
  • Mădălina Costinela Stănică,
  • Irina Enăchescu,
  • Ana-Maria Țenea Cojan,
  • Valentina Căluianu,
  • Gabriel Florin Răzvan Mogoș and
  • Liviu Vasile

19 November 2025

Background: Laser hemorrhoidoplasty (LHP) is a minimally invasive alternative to excisional hemorrhoidectomy, with promising short-term outcomes. However, predictors of postoperative pain, bleeding, and recovery remain insufficiently characterized. M...

  • Article
  • Open Access
3,482 Views
20 Pages

This study focuses on analyzing the in vitro release characteristics, as well as improving the penetration rate and stability of hydrocortisone acetate and pramoxine. This medication combination (hydrocortisone and pramoxine) is the first generic dru...

  • Systematic Review
  • Open Access
2,141 Views
17 Pages

Biopsychosocial Strategies for Alleviating Low Back Pain in Late Mothers: A Systematic Review

  • Darshika Thejani Bulathwatta,
  • Małgorzata Treppner,
  • Monika Januszkiewicz,
  • Paulina Głowacka,
  • Judyta Borchet,
  • Asanka Bulathwatta and
  • Mariola Bidzan

Background: Low back pain (LBP) in older mothers is a prevalent and multifaceted condition influenced by a range of biopsychosocial factors. As the trend of late motherhood increases globally, it is essential to understand how LBP affects this popula...

  • Review
  • Open Access
35 Citations
20,859 Views
19 Pages

14 July 2023

Knowledge about the pharmacological benefits of different seeds is an important factor for the cultivation and application of medicinal herbs and plants. The seeds of medicinal plants are stores of valuable and active secondary metabolites that have...

  • Article
  • Open Access
5 Citations
2,800 Views
9 Pages

The Spectrum of Co-Diagnoses in Patients with Colorectal Cancer: A Retrospective Cohort Study of 17,824 Outpatients in Germany

  • Sven H. Loosen,
  • David Schöler,
  • Simon Labuhn,
  • Alexander Mertens,
  • Markus S Jördens,
  • Mark Luedde,
  • Karel Kostev,
  • Tom Luedde and
  • Christoph Roderburg

6 August 2022

Background: The prognosis of colorectal cancer (CRC) patients is determined to a decisive extent by comorbidities. On the other hand, anti-cancer treatments for CRC are associated with relevant toxicities and may therefore cause additional comorbidit...

  • Case Report
  • Open Access
3 Citations
4,903 Views
7 Pages

8 February 2024

Introduction—This report illuminates the distinctive features of a successfully managed Retzius space infection arising from a complex perirectal abscess. It adds novel insights to the scientific literature by addressing the rarity of such occu...

  • Article
  • Open Access
68 Views
14 Pages

Prevalence and Determinants of Anorectal Disorders in Adult Patients with Urinary Incontinence: A Retrospective Cohort Study

  • Reem Alharbi,
  • Ebtesam Almajed,
  • Norah Alqntash,
  • Ebtihag O. Alenzi,
  • Rawan Bin Salamah,
  • Reem Altamimi and
  • Kayan Alotaibi

1 February 2026

Background/Objectives: Pelvic floor dysfunction (PFD) encompasses urinary incontinence (UI), anorectal disorders (ARDs), and other related conditions that frequently coexist. Evidence on the prevalence and determinants of ARD among patients with UI,...