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9 Results Found

  • Review
  • Open Access
12 Citations
7,846 Views
37 Pages

In Vitro Skin Models for Skin Sensitisation: Challenges and Future Directions

  • Ignacio Losada-Fernández,
  • Ane San Martín,
  • Sergio Moreno-Nombela,
  • Leticia Suárez-Cabrera and ,
  • Leticia Valencia,
  • Paloma Pérez-Aciego and
  • Diego Velasco
  • + 2 authors+ 0 author

12 August 2025

Allergic contact dermatitis is one of the most common adverse events associated with cosmetic use. Accordingly, assessment of skin sensitisation hazard is required for safety evaluation of cosmetic ingredients. The transition to the use of alternativ...

(This article belongs to the Section Cosmetic Dermatology)
  • Review
  • Open Access
67 Citations
16,163 Views
40 Pages

Contact Allergy—Emerging Allergens and Public Health Impact

  • Wolfgang Uter,
  • Thomas Werfel,
  • Jean-Pierre Lepoittevin and
  • Ian R. White

Contact allergy (sensitisation) and allergic contact dermatitis (ACD) resulting from it have a considerable public health impact. For the present review, all pertinent articles were systematically searched via Medline and Web of Science™; addit...

(This article belongs to the Special Issue Toxicology and Public Health)
  • Review
  • Open Access
15 Citations
11,788 Views
11 Pages

Contact Allergy Induced by Mango (Mangifera indica): A Relevant Topic?

  • Elena Camelia Berghea,
  • Mihai Craiu,
  • Selda Ali,
  • Sabina Loredana Corcea and
  • Roxana Silvia Bumbacea

13 November 2021

Introduction: The most common clinical manifestation of mango allergy is contact dermatitis, which can be localized or systemic. The sensitising substances that have long been suspected are alk(en)yl catechols and/or alk(en)yl resorcinols. Methods: W...

(This article belongs to the Special Issue Chronic Inflammatory Skin Diseases: Current Treatment and Future)
  • Review
  • Open Access
60 Citations
11,773 Views
21 Pages

IgE sensitisation has increased significantly over the last decades and is a crucial factor in the development of allergic diseases. IgE antibodies are produced by B cells through the process of antigen presentation by dendritic cells, subsequent dif...

(This article belongs to the Special Issue Molecular Research on Mucosal Immunity)
  • Review
  • Open Access
65 Citations
21,880 Views
39 Pages

Contact Allergy: A Review of Current Problems from a Clinical Perspective

  • Wolfgang Uter,
  • Thomas Werfel,
  • Ian R. White and
  • Jeanne D. Johansen

Contact allergy is common, affecting 27% of the general population in Europe. Original publications, including case reports, published since 2016 (inclusive) were identified with the aim of collating a full review of current problems in the field. To...

(This article belongs to the Special Issue The Epidemiology of Allergy)
  • Article
  • Open Access
21 Citations
4,754 Views
24 Pages

Influence of Porous Dressings Based on Butyric-Acetic Chitin Co-Polymer on Biological Processes In Vitro and In Vivo

  • Witold Sujka,
  • Zbigniew Draczynski,
  • Beata Kolesinska,
  • Ilona Latanska and ,
  • Zenon Jastrzebski,
  • Zbigniew Rybak and
  • Boguslawa Zywicka
  • + 2 authors+ 0 author

23 March 2019

In spite of intensively conducted research allowing for the development of more and more advanced wound dressing materials, there is still a need for dressings that stimulate not only reparative and regenerative processes, but also have a positive ef...

(This article belongs to the Special Issue Multifunctional Materials in Tissue Regeneration)
  • Article
  • Open Access
6 Citations
4,875 Views
20 Pages

15 October 2022

The primary role of Notch is to specify cellular identities, whereby the cells respond to amazingly small changes in Notch signalling activity. Hence, dosage of Notch components is crucial to regulation. Central to Notch signal transduction are CSL p...

(This article belongs to the Special Issue Notch Signaling in Health and Disease)
  • Article
  • Open Access
7 Citations
3,568 Views
14 Pages

Aspergillus fumigatus Supernatants Disrupt Bronchial Epithelial Monolayers: Potential Role for Enhanced Invasion in Cystic Fibrosis

  • Katie Dunne,
  • Emma Reece,
  • Siobhán McClean,
  • Sean Doyle and ,
  • Thomas R. Rogers,
  • Philip Murphy and
  • Julie Renwick
  • + 2 authors+ 0 author

19 April 2023

Aspergillus fumigatus is the most commonly isolated fungus in chronic lung diseases, with a prevalence of up to 60% in cystic fibrosis patients. Despite this, the impact of A. fumigatus colonisation on lung epithelia has not been thoroughly explored....

(This article belongs to the Special Issue New Insights into Current Understanding of Host–Fungal Interactions)
  • Review
  • Open Access
  • Best Paper Award
59 Citations
28,219 Views
21 Pages

Consumer preferences, safety, and sustainability aspects of conventional cosmetic ingredients have contributed to an increase in the demand for natural cosmetic ingredients and products. Naturally derived active cosmetic agents and excipients may com...

(This article belongs to the Special Issue Natural Sources for Cosmetic Ingredients: Challenges and Innovations)