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22 Results Found

  • Article
  • Open Access
9 Citations
3,513 Views
20 Pages

MR Imaging–Pathologic Correlation of Uveal Melanomas Undergoing Secondary Enucleation after Proton Beam Radiotherapy

  • Pietro Valerio Foti,
  • Corrado Inì,
  • Mario Travali,
  • Renato Farina,
  • Stefano Palmucci,
  • Corrado Spatola,
  • Rocco Luca Emanuele Liardo,
  • Roberto Milazzotto,
  • Luigi Raffaele and
  • Antonio Basile
  • + 9 authors

10 May 2021

Background: Currently, radiotherapy represents the most widely employed therapeutic option in patients with uveal melanoma. Although the effects of proton beam radiotherapy on uveal melanoma end ocular tissues have been histologically documented, the...

  • Review
  • Open Access
8 Citations
5,774 Views
16 Pages

Plaque Radiotherapy for Ocular Melanoma

  • George Naveen Thomas,
  • I-Ling Chou and
  • Lingam Gopal

3 October 2024

Plaque radiotherapy is an effective treatment modality for medium-sized ocular tumors such as uveal melanoma. The authors review the available literature and concisely summarize the current state of the art of ophthalmic plaque brachytherapy. The cho...

  • Article
  • Open Access
11 Citations
2,073 Views
15 Pages

Evaluation of Radiation Doses Received by Physicians during Permanent 198Au Grain Implant Brachytherapy for Oral Cancer

  • Yohei Inaba,
  • Keiichi Jingu,
  • Masaki Fujisawa,
  • Kazuki Otomo,
  • Hiroki Ishii,
  • Toshiki Kato,
  • Yuuki Murabayashi,
  • Masatoshi Suzuki,
  • Masayuki Zuguchi and
  • Koichi Chida

10 July 2024

Brachytherapy is a practical, effective procedure for the local treatment of cancer; it delivers a high radiation dose to a limited tissue volume while sparing the surrounding normal tissues. Although the clinical benefit of brachytherapy is clear, t...

  • Article
  • Open Access
25 Citations
1,057 Views
5 Pages

The Changing Landscape of Brachytherapy for Cervical Cancer: A Canadian Practice Survey

  • T. Phan,
  • L. Mula-Hussain,
  • S. Pavamani,
  • A. Pearce,
  • D. D’Souza,
  • N.G. Patil,
  • L. Traptow and
  • C.M. Doll

1 October 2015

Background: We documented changes in practice from 2009 to 2012 for cervical cancer brachytherapy in Canada. Methods: Centres with gynecologic brachytherapy services were sent an e-mail questionnaire querying their 2012 practice. Responses are report...

  • Article
  • Open Access
5 Citations
2,887 Views
13 Pages

Impact of the FIGO 2023 Staging System on the Adjuvant Treatment of Endometrial Cancer: A Comparative Analysis with FIGO 2009

  • Federico Ferrari,
  • Elisa Gozzini,
  • Jacopo Conforti,
  • Andrea Giannini,
  • Fabio Barra,
  • Anna Fichera,
  • Filippo Alberto Ferrari,
  • Hooman Soleymani majd and
  • Franco Odicino

10 March 2025

Background: ProMisE (Proactive Molecular Risk Classifier for Endometrial Cancer) has brought about the publication of the FIGO 2023 staging system with a significant impact in practice for endometrial cancer (EC). Methods: In this comparative study,...

  • Review
  • Open Access
214 Citations
24,009 Views
19 Pages

Magnetic Actuation Based Motion Control for Microrobots: An Overview

  • Tiantian Xu,
  • Jiangfan Yu,
  • Xiaohui Yan,
  • Hongsoo Choi and
  • Li Zhang

15 September 2015

Untethered, controllable, mobile microrobots have been proposed for numerous applications, ranging from micro-manipulation, in vitro tasks (e.g., operation of microscale biological substances) to in vivo applications (e.g., targeted drug delivery; br...

  • Article
  • Open Access
4,478 Views
10 Pages

Single-Fraction Adjuvant Electronic Brachytherapy after Resection of Conjunctival Carcinoma

  • Gustavo R. Sarria,
  • Solon Serpa,
  • Mario Buitrago,
  • Paola Fuentes Rivera,
  • Diego Ramirez,
  • Frank A. Giordano and
  • Gustavo J. Sarria

26 January 2021

A retrospective study was performed to assess the outcomes of a single-fraction adjuvant electronic brachytherapy (e-BT) approach for patients with squamous cell conjunctival carcinoma (SCCC). Forty-seven patients with T1–T3 SCCC were included. All p...

  • Review
  • Open Access
22 Citations
8,336 Views
23 Pages

Personalized Radiation Therapy in Cancer Pain Management

  • Ewa Sierko,
  • Dominika Hempel,
  • Konrad Zuzda and
  • Marek Z. Wojtukiewicz

19 March 2019

The majority of advanced cancer patients suffer from pain, which severely deteriorates their quality of life. Apart from analgesics, bisphosphonates, and invasive methods of analgesic treatment (e.g., intraspinal and epidural analgesics or neurolytic...

  • Review
  • Open Access
7 Citations
6,094 Views
17 Pages

Iatrogenic Ocular Surface Diseases Occurring during and/or after Different Treatments for Ocular Tumours

  • Giuseppe Giannaccare,
  • Federico Bernabei,
  • Martina Angi,
  • Marco Pellegrini,
  • Antonio Maestri,
  • Vito Romano,
  • Vincenzo Scorcia and
  • Pierre-Räphael Rothschild

16 April 2021

The ocular surface represents a finely regulated system that allows the protection of the eye. It is particularly susceptible to different treatments for intraocular tumours, such as uveal melanoma and conjunctival cancers. Traditionally, the managem...

  • Article
  • Open Access
7 Citations
3,442 Views
17 Pages

Complete Geometric Analysis Using the Study SE(3) Parameters for a Novel, Minimally Invasive Robot Used in Liver Cancer Treatment

  • Iosif Birlescu,
  • Manfred Husty,
  • Calin Vaida,
  • Nicolae Plitea,
  • Abhilash Nayak and
  • Doina Pisla

7 December 2019

The paper presents a complete geometric analysis of a novel parallel medical robotic system designed for minimally invasive treatment of hepatic tumors using brachytherapy, ablation or targeted chemotherapy. An algebraic method based on the study par...

  • Review
  • Open Access
17 Citations
4,011 Views
19 Pages

Ceramics, Glass and Glass-Ceramics for Personal Radiation Detectors

  • Szymon Świontek,
  • Marcin Środa and
  • Wojciech Gieszczyk

12 October 2021

Different types of ceramics and glass have been extensively investigated due to their application in brachytherapy, radiotherapy, nuclear medicine diagnosis, radioisotope power systems, radiation processing of food, geological and archaeological dati...

  • Review
  • Open Access
15 Citations
6,181 Views
12 Pages

Interventions Preventing Vaginitis, Vaginal Atrophy after Brachytherapy or Radiotherapy Due to Malignant Tumors of the Female Reproductive Organs—A Systematic Review

  • Adrianna Wierzbicka,
  • Dorota Mańkowska-Wierzbicka,
  • Stanisław Cieślewicz,
  • Marta Stelmach-Mardas and
  • Marcin Mardas

Background: Radiotherapy, as a method of treatment of cervical and uterine cancers, may induce severe late-onset vaginal side effects. Unfortunately, little evidence on the management of adverse effects has been presented. This study aimed to evaluat...

  • Article
  • Open Access
20 Citations
4,219 Views
19 Pages

Evaluation of Dimer of Epicatechin from an Endophytic Fungus Curvularia australiensis FC2AP on Acute Toxicity Levels, Anti-Inflammatory and Anti-Cervical Cancer Activity in Animal Models

  • Vellingiri Manon Mani,
  • Arockiam Jeyasundar Parimala Gnana Soundari,
  • Balamuralikrishnan Balasubramanian,
  • Sungkwon Park,
  • Utthapon Issara,
  • Kathirvel Preethi and
  • Wen-Chao Liu

27 January 2021

Cervical cancer, as the most frequent cancer in women globally and accounts almost 14% in India. It can be prevented or treated with vaccines, radiation, chemotherapy, and brachytherapy. The chemotherapeutic agents cause adverse post effects by the d...

  • Review
  • Open Access
5 Citations
5,914 Views
23 Pages

Oxidative Stress, Inflammation, and Antioxidant Strategies in Cervical Cancer—A Narrative Review

  • Ecaterina Tomaziu-Todosia Anton,
  • Gabriel-Ioan Anton,
  • Ioana-Sadiye Scripcariu,
  • Irina Dumitrașcu,
  • Dragos Viorel Scripcariu,
  • Ioana-Miruna Balmus,
  • Cătălina Ionescu,
  • Mălina Visternicu and
  • Demetra Gabriela Socolov

Cervical cancer ranks third among malignant diseases of the female reproductive system and progressively develops through a series of pathological changes known as cervical intraepithelial neoplasia (CIN). Despite being extremely aggressive and causi...

  • Review
  • Open Access
3 Citations
3,134 Views
15 Pages

26 February 2023

Treatment personalization in Molecular Radiotherapy (MRT) relies on pre- and post-treatment SPECT/ PET-based images and measurements to obtain a patient-specific absorbed dose-rate distribution map and its evolution over time. Unfortunately, the numb...

  • Review
  • Open Access
9 Citations
4,111 Views
17 Pages

Interventional Treatment Strategies in Intrahepatic Cholangiocarcinoma and Perspectives for Combined Hepatocellular-Cholangiocarcinoma

  • Timo Alexander Auer,
  • Federico Collettini,
  • Laura Segger,
  • Uwe Pelzer,
  • Raphael Mohr,
  • Felix Krenzien,
  • Bernhard Gebauer,
  • Dominik Geisel,
  • Clarissa Hosse and
  • Uli Fehrenbach
  • + 1 author

8 May 2023

cHCC-CCA is an uncommon type of liver cancer that exhibits clinical and pathological characteristics of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), which are the two main forms of primary liver cancer. The similarity to HCC and...

  • Systematic Review
  • Open Access
5 Citations
6,782 Views
13 Pages

Intraoperative Radiotherapy with Balloon-Based Electronic Brachytherapy System—A Systematic Review and First Bulgarian Experience in Breast Cancer Patients

  • Desislava Kostova-Lefterova,
  • Mariela Vasileva-Slaveva,
  • Svilen Maslyankov,
  • Assia Konsoulova,
  • Margarita Atanasova,
  • Tsvetelina Paycheva,
  • Alexandrina Vlahova,
  • Marusya Genadieva-Yordanova,
  • Ginka Prodanova and
  • Ivo Petrov
  • + 8 authors

3 October 2021

(1) Background: We aimed to analyze currently available studies with intraoperative radiotherapy (IORT) as a choice of treatment where the Xoft Axxent® electronic brachytherapy (eBx) system was used as a single-dose irradiation and an exclusive radio...

  • Article
  • Open Access
1 Citations
3,435 Views
14 Pages

Design and Material Characterization of an Inflatable Vaginal Dilator

  • Po-Han Chen,
  • Yu Ming Li,
  • Karcher Morris,
  • Milan T. Makale,
  • Jyoti Mayadev and
  • Frank E. Talke

24 February 2024

There are more than 13,000 new cases of cervical cancer each year in the United States and approximately 245,000 survivors. External beam radiation and brachytherapy are the front-line treatment modalities, and 60% of patients develop vaginal damage...

  • Review
  • Open Access
25 Citations
5,718 Views
21 Pages

New Perspectives for Eye-Sparing Treatment Strategies in Primary Uveal Melanoma

  • Krzysztof Bilmin,
  • Kamil J. Synoradzki,
  • Anna M. Czarnecka,
  • Mateusz J. Spałek,
  • Tamara Kujawska,
  • Małgorzata Solnik,
  • Piotr Merks,
  • Mario Damiano Toro,
  • Robert Rejdak and
  • Michał Fiedorowicz

28 December 2021

Uveal melanoma is the most common intraocular malignancy and arises from melanocytes in the choroid, ciliary body, or iris. The current eye-sparing treatment options include surgical treatment, plaque brachytherapy, proton beam radiotherapy, stereota...

  • Article
  • Open Access
5 Citations
3,362 Views
10 Pages

Vaginal Toxicity Management in Patients with Locally Advanced Cervical Cancer following Exclusive Chemoradiation—A Nationwide Survey on Knowledge and Attitudes by the Italian Association of Radiotherapy and Clinical Oncology (AIRO) Gynecology Study Group

  • Francesca De Felice,
  • Lisa Vicenzi,
  • Gabriella Macchia,
  • Andrea Vavassori,
  • Elisabetta Perrucci,
  • Annamaria Cerrotta,
  • Valentina Lancellotta,
  • Sofia Meregalli,
  • Lorena Draghini and
  • Vitaliana De Sanctis
  • + 1 author

16 February 2023

Background and Objective: Exclusive radiotherapy, including external beam radiotherapy (EBRT) and interventional radiotherapy/brachytherapy (IRT/BT), with concurrent cisplatin-based chemotherapy, represents the standard of care in patients with local...

  • Review
  • Open Access
12 Citations
4,293 Views
14 Pages

Palliation in Gallbladder Cancer: The Role of Gastrointestinal Endoscopy

  • Tommaso Schepis,
  • Ivo Boškoski,
  • Andrea Tringali,
  • Vincenzo Bove and
  • Guido Costamagna

26 March 2022

Gallbladder cancer is a rare malignancy burdened by poor prognosis with an estimated 5-year survival of 5% to 13% due to late presentation, early infiltration of surrounding tissues, and lack of successful treatments. The only curative approach is su...

  • Article
  • Open Access
1,053 Views
17 Pages

Integrating Novel and Classical Prognostic Factors in Locally Advanced Cervical Cancer: A Machine Learning-Based Predictive Model (ESTHER Study)

  • Federica Medici,
  • Martina Ferioli,
  • Arina Alexandra Zamfir,
  • Milly Buwenge,
  • Gabriella Macchia,
  • Francesco Deodato,
  • Paolo Castellucci,
  • Luca Tagliaferri,
  • Anna Myriam Perrone and
  • Savino Cilla
  • + 8 authors

15 April 2025

Background/Objective: This study aimed to assess the prognostic significance of pretreatment nutritional and systemic inflammatory indices (IIs), and body composition parameters in patients with locally advanced cervical cancer (LACC) treated with ch...