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14 Results Found

  • Article
  • Open Access
1,012 Views
4 Pages

1 August 2016

Hypopituitarism in leukemia is very rare. In addition, central nervous system (cns) relapse and leukemic retinopathy in childhood acute lymphoblastic leukemia (all) have declined with the use of modern systemic chemotherapy that includes cns prophyla...

  • Case Report
  • Open Access
8 Citations
3,455 Views
8 Pages

Neurological Presentation of Giant Pituitary Tumour Apoplexy: Case Report and Literature Review of a Rare but Life-Threatening Condition

  • Valentina Puglisi,
  • Elisabetta Morini,
  • Fiammetta Biasini,
  • Luisa Vinciguerra,
  • Giuseppe Lanza and
  • Placido Bramanti

13 March 2022

Background: Giant pituitary adenomas are benign intracranial tumours with a diameter ≥4 cm. Even if hormonally non-functional, they may still cause local extension, leading to symptoms that include mostly gland dysfunction, mass effects, and, much le...

(This article belongs to the Section Endocrinology & Metabolism)
  • Review
  • Open Access
22 Citations
7,643 Views
11 Pages

Hypopituitarism after Orthohantavirus Infection: What is Currently Known?

  • Soerajja Bhoelan,
  • Thomas Langerak,
  • Danny Noack,
  • Linda van Schinkel,
  • Els van Nood,
  • Eric C.M. van Gorp,
  • Barry Rockx and
  • Marco Goeijenbier

10 April 2019

Several case reports have described hypopituitarism following orthohantavirus infection, mostly following Puumala virus. The pathogenesis of this seemingly rare complication of orthohantavirus infection remains unknown. This review explores the possi...

(This article belongs to the Special Issue Hantaviruses)
  • Review
  • Open Access
31 Citations
7,508 Views
11 Pages

Hypothalamic-Pituitary Autoimmunity and Traumatic Brain Injury

  • Federica Guaraldi,
  • Silvia Grottoli,
  • Emanuela Arvat and
  • Ezio Ghigo

19 May 2015

Background: Traumatic brain injury (TBI) is a leading cause of secondary hypopituitarism in children and adults, and is responsible for impaired quality of life, disabilities and compromised development. Alterations of pituitary function can occur at...

(This article belongs to the Special Issue Neuroendocrine Disturbances after Brain Damage)
  • Review
  • Open Access
65 Citations
12,549 Views
25 Pages

Update of Endocrine Dysfunction following Pediatric Traumatic Brain Injury

  • Kent Reifschneider,
  • Bethany A. Auble and
  • Susan R. Rose

31 July 2015

Traumatic brain injuries (TBI) are common occurrences in childhood, often resulting in long term, life altering consequences. Research into endocrine sequelae following injury has gained attention; however, there are few studies in children. This pap...

(This article belongs to the Special Issue Neuroendocrine Disturbances after Brain Damage)
  • Case Report
  • Open Access
7 Citations
6,653 Views
14 Pages

An Approach to Traumatic Brain Injury-Related Hypopituitarism: Overcoming the Pediatric Challenges

  • Raluca Maria Vlad,
  • Alice Ioana Albu,
  • Irina Delia Nicolaescu,
  • Ruxandra Dobritoiu,
  • Mara Carsote,
  • Florica Sandru,
  • Dragos Albu and
  • Daniela Păcurar

Traumatic brain injury (TBI)-related hypopituitarism is a rare polymorphic complication of brain injury, with very little data, particularly concerning children and teenagers. This is a comprehensive review of the literature regarding this pathology,...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
11 Citations
2,921 Views
13 Pages

Risk Factors, Radiological and Clinical Outcomes in Subclinical and Clinical Pituitary Apoplexy

  • Betina Biagetti,
  • Silvana Sarria-Estrada,
  • Esteban Cordero Asanza,
  • Anas Chaachou-Charradi,
  • Yiken Karelys Ng-Wong,
  • Marta Cicuendez,
  • Irene Hernandez,
  • Alba Rojano-Toimil,
  • Pilar Costa and
  • Rafael Simò
  • + 2 authors

8 December 2022

Background: Pituitary apoplexy (PA) can be symptomatic, namely acute apoplexy (APA), or asymptomatic or subclinical (SPA). Objective: To describe the clinical characteristics and evolution of the patients with APA compared to SPA Patients and methods...

(This article belongs to the Section Endocrinology & Metabolism)
  • Review
  • Open Access
12 Citations
3,893 Views
14 Pages

15 October 2021

Hypophysitis is a rare and potentially life-threatening disease, characterized by an elevated risk of complications, such as the occurrence of acute central hypoadrenalism, persistent hypopituitarism, or the extension of the inflammatory process to t...

(This article belongs to the Special Issue Novel Biomarkers in Translational Medicine of Chronic and Autoimmune Diseases)
  • Review
  • Open Access
3 Citations
2,993 Views
15 Pages

Epidemiology of Endocrine Dysfunctions in Pediatric Patients with Previous Central Nervous System Infection: A Scoping Review of the Literature

  • Giorgio Sodero,
  • Clelia Cipolla,
  • Laura Martino,
  • Carolina Gentili,
  • Claudia Rendeli and
  • Danilo Buonsenso

28 June 2024

Purpose The incidence of endocrine sequelae following central nervous system (CNS) infections in pediatric age is not known. We conducted this scoping review to assess the incidence of endocrinological alterations in patients with prior CNS infection...

(This article belongs to the Section Pediatric Infectious Diseases)
  • Review
  • Open Access
49 Citations
11,115 Views
15 Pages

Growth Hormone Deficiency Following Traumatic Brain Injury

  • Oratile Kgosidialwa,
  • Osamah Hakami,
  • Hafiz Muhammad Zia-Ul-Hussnain and
  • Amar Agha

Traumatic brain injury (TBI) is fairly common and annually affects millions of people worldwide. Post traumatic hypopituitarism (PTHP) has been increasingly recognized as an important and prevalent clinical entity. Growth hormone deficiency (GHD) is...

(This article belongs to the Special Issue Steroids and Lipophilic Hormones, and Their Actions)
  • Review
  • Open Access
136 Citations
35,317 Views
13 Pages

Long-term Effects of Snake Envenoming

  • Subodha Waiddyanatha,
  • Anjana Silva,
  • Sisira Siribaddana and
  • Geoffrey K. Isbister

31 March 2019

Long-term effects of envenoming compromise the quality of life of the survivors of snakebite. We searched MEDLINE (from 1946) and EMBASE (from 1947) until October 2018 for clinical literature on the long-term effects of snake envenoming using differe...

(This article belongs to the Section Animal Venoms)
  • Article
  • Open Access
1,651 Views
12 Pages

Hemorrhagic PitNets Are Associated with Previous Vascular Events and Result in Worse Endocrine Outcome

  • Harold F. Hounchonou,
  • Josef M. Lang,
  • Katja Döring,
  • Christoph Terkamp,
  • Holger Leitolf,
  • Shadi Al-Afif,
  • Elvis J. Hermann,
  • Christian Hartmann and
  • Joachim K. Krauss

8 December 2024

Background: Pituitary apoplexy is a potentially life-threatening condition that most often results from hemorrhage into a preexisting pituitary neuroendocrine tumor (PitNet) presenting with acute headache, visual impairment and endocrine dysfunction....

(This article belongs to the Special Issue Hot Topics in Neuro-Oncology)
  • Review
  • Open Access
17 Citations
6,208 Views
20 Pages

Unveiling the Etiopathogenic Spectrum of Hypophysitis: A Narrative Review

  • Sara Menotti,
  • Antonella Giampietro,
  • Salvatore Raia,
  • Miriam Veleno,
  • Flavia Angelini,
  • Tommaso Tartaglione,
  • Simona Gaudino,
  • Francesco Doglietto,
  • Laura De Marinis and
  • Sabrina Chiloiro
  • + 2 authors

30 July 2023

Hypophysitis, a rare inflammatory disorder of the pituitary gland, has seen an uptick in reported cases in recent years. Our objective is to summarize the most recent research on the etiopathogenesis, molecular mechanisms, and genetics of both primar...

(This article belongs to the Section Personalized Therapy and Drug Delivery)
  • Review
  • Open Access
32 Citations
10,412 Views
19 Pages

25 February 2024

Hemochromatosis represents clinically one of the most important genetic storage diseases of the liver caused by iron overload, which is to be differentiated from hepatic iron overload due to excessive iron release from erythrocytes in patients with g...

(This article belongs to the Special Issue Heavy Metal Toxicity: Molecular Mechanisms and Potential Therapies)