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20 Results Found

  • Systematic Review
  • Open Access
2 Citations
9,164 Views
12 Pages

Introduction: Uterine transplantation is currently the only treatment that allows women with absolute uterine factor infertility (AUFI) to gestate and give birth. Objective: This systematic review aims to analyze the available evidence on uterine tra...

  • Systematic Review
  • Open Access
37 Citations
7,017 Views
17 Pages

Uterine Factor Infertility, a Systematic Review

  • Camille Sallée,
  • François Margueritte,
  • Pierre Marquet,
  • Pascal Piver,
  • Yves Aubard,
  • Vincent Lavoué,
  • Ludivine Dion and
  • Tristan Gauthier

21 August 2022

Uterine factor infertility (UFI) is defined as a condition resulting from either a complete lack of a uterus or a non-functioning uterus due to many causes. The exact prevalence of UFI is currently unknown, while treatments to achieve pregnancy are v...

(This article belongs to the Section Obstetrics & Gynecology)
  • Systematic Review
  • Open Access
4 Citations
3,307 Views
13 Pages

Uterus Transplantation as Infertility Treatment in Gynecological Cancer Survivors: A Systematic Review

  • Ermioni Tsarna,
  • Anna Eleftheriades,
  • Alkis Matsas,
  • Olga Triantafyllidou and
  • Panagiotis Christopoulos

28 May 2024

Background: The aim of this systematic review is to summarize the evidence regarding the acceptance of uterine transplantation as infertility treatment among gynecological cancer survivors, surgical and pregnancy outcomes post-transplantation for gyn...

(This article belongs to the Section Obstetrics & Gynecology)
  • Feature Paper
  • Article
  • Open Access
4 Citations
2,701 Views
12 Pages

29 May 2024

Background: Uterus transplantation (UTx) provides women with absolute uterine-factor infertility (AUFI) the opportunity to carry their own pregnancy and deliver a child. There are multiple ethical and medical concerns associated with UTx. Since the l...

(This article belongs to the Special Issue New Advances in Uterus and Ovarian Transplantation)
  • Article
  • Open Access
58 Citations
8,401 Views
15 Pages

4 February 2021

Introduction: Uterus transplantation (UTx) is a rapidly evolving treatment of uterine-factor infertility. We report the results of the first 10 UTx procedures performed at our institution. Methods: The program started in April 2016 as a two-arm study...

(This article belongs to the Special Issue Uterus Transplantation)
  • Editorial
  • Open Access
1 Citations
2,649 Views
2 Pages

For women with absolute uterine factor infertility (AUFI), uterus transplantation (UTx) is now an alternative to gestational surrogacy or adoption in order to have a child [...]

(This article belongs to the Section Solid Organ Transplantation)
  • Review
  • Open Access
542 Views
16 Pages

11 July 2026

Background/Objectives: According to the World Health Organization, approximately one in six couples experience infertility during their lifetime, accounting for about 15–17% of the reproductive-aged population worldwide. Absolute uterine factor...

(This article belongs to the Section Obstetrics & Gynecology)
  • Systematic Review
  • Open Access
6 Citations
7,491 Views
18 Pages

Uterine Transplantation: Advances, Challenges, and Future Perspectives

  • Ana Pereira,
  • Flávia Ribeiro,
  • Sandra Soares and
  • Hélder Ferreira

Background: Infertility is a multifactorial condition with medical, psychological, demographic, and economic impacts. Around 3–5% of cases are due to uterine dysfunction. Absolute uterine factor infertility (AUFI) refers to infertility caused e...

  • Article
  • Open Access
5 Citations
2,954 Views
10 Pages

Radiologic Evaluation of Uterine Vasculature of Uterus Transplant Living Donor Candidates: DUETS Classification

  • Jakub Kristek,
  • Liza Johannesson,
  • Matthew Paul Clemons,
  • Dana Kautznerova,
  • Jaroslav Chlupac,
  • Jiri Fronek,
  • Giuliano Testa and
  • Gregory dePrisco

8 August 2022

Uterus transplantation is a treatment solution for women suffering from absolute uterine factor infertility. As much as 19.5% of uterus-transplanted patients underwent urgent graft hysterectomy due to thrombosis/hypoperfusion. The necessity to identi...

(This article belongs to the Special Issue Uterus and Ovarian Transplantation)
  • Article
  • Open Access
2 Citations
1,095 Views
15 Pages

29 September 2025

Background/Objectives: A novel treatment of absolute uterine factor infertility is uterus transplantation. In preparation for human surgery, autotransplantation was performed in a sheep model to assess ischemia-reperfusion injury of the uterine wall....

(This article belongs to the Special Issue Pathogenesis, Diagnostics and Therapeutics in Obsterics and Gynaecology (2nd Edition))
  • Feature Paper
  • Review
  • Open Access
11 Citations
5,404 Views
9 Pages

Deceased Donation Uterus Transplantation: A Review

  • Natasha Hammond-Browning and
  • Si Liang Yao

Uterus transplantation (UTx) offers women with absolute uterine factor infertility the option to gestate and birth their own biologically related child. The first birth following living donation UTx happened in 2014. The first birth following decease...

(This article belongs to the Section Solid Organ Transplantation)
  • Review
  • Open Access
20 Citations
5,933 Views
13 Pages

Current Progress in Uterus Transplantation Research in Asia

  • Iori Kisu,
  • Yu Liu,
  • Gaowen Chen,
  • Min Jong Song,
  • Cherry Yin-Yi Chang,
  • Tan Hak Koon,
  • Kouji Banno and
  • Daisuke Aoki

14 February 2019

Uterus transplantation (UTx) is now a possible approach for women with absolute uterine factor infertility to deliver a child, following the first successful delivery by Brännström et al. in Sweden in September 2014. This remarkable achieve...

(This article belongs to the Special Issue Uterus Transplantation)
  • Article
  • Open Access
2 Citations
926 Views
16 Pages

First Experience with Hypothermic Oxygenated Perfusion in Human Uteri: Feasibility and Metabolic Characterization

  • Keyue Sun,
  • Nasim Eshraghi,
  • Fernanda Walsh Fernandes,
  • Sangeeta Satish,
  • Chunbao Jiao,
  • Fatma Selin Yildirim,
  • Geofia Crasta,
  • Omer F. Karakaya,
  • Koki Takase and
  • Andrea Schlegel
  • + 14 authors

8 April 2026

Background: Uterus transplantation (UTx) is an emerging treatment for absolute uterine factor infertility. However, the use of deceased donors is limited, and donation after circulatory death (DCD) has not yet been utilized. Ischemic injury remains a...

(This article belongs to the Special Issue New Advances in Uterus and Ovarian Transplantation: 2nd Edition)
  • Review
  • Open Access
3 Citations
4,193 Views
10 Pages

Pregnancy and Delivery After Solid Organ and Uterus Transplantation: A Review

  • Iori Kisu,
  • Mitsutoshi Yamada,
  • Satoru Ikenoue and
  • Wataru Yamagami

19 July 2025

In recent years, advances in organ transplantation medicine have led to an increase in pregnancies and births following transplantation. Pregnancy after organ transplantation is considered high-risk, and its impact on both the recipient and the child...

(This article belongs to the Special Issue New Advances in Uterus and Ovarian Transplantation: 2nd Edition)
  • Article
  • Open Access
6 Citations
1,809 Views
7 Pages

Uterus Transplantation from Deceased Donors: First Italian Experience

  • Pierfrancesco Veroux,
  • Paolo Scollo,
  • Alessia Giaquinta,
  • Giuseppe Roscitano,
  • Martina Maria Giambra,
  • Basilio Pecorino,
  • Concetta De Pasquale,
  • Giuseppe Scibilia,
  • Maria Luisa Pistorio and
  • Massimiliano Veroux

13 November 2024

Background: Uterus transplantation (UTx) is currently the only available treatment for absolute uterine factor infertility. Deceased donors have recently emerged as a valid alternative to living donors for uterus transplantation, with similar results...

(This article belongs to the Section Reproductive Medicine & Andrology)
  • Article
  • Open Access
8 Citations
3,017 Views
10 Pages

Custodiol-N Is Superior to Custodiol® Solution in Experimental Rat Uterus Preservation

  • Viktorija Zitkute,
  • Mindaugas Kvietkauskas,
  • Vygante Maskoliunaite,
  • Bettina Leber,
  • Diana Ramasauskaite,
  • Kestutis Strupas,
  • Philipp Stiegler and
  • Peter Schemmer

28 October 2020

Uterus transplantation (UTx) is the first and only available treatment for women with absolute uterine factor infertility. However, clinical application is limited by the lack of organs, ischemia/reperfusion injury, as well as immunosuppression after...

(This article belongs to the Special Issue New Frontiers in Organ Preservation and Hepatoprotection)
  • Article
  • Open Access
385 Views
11 Pages

2 September 2026

Background/Objectives: Endometrial polyps are a prevalent pathological condition within the uterine cavity. While the majority of lesions are classified as benign, histopathological examinations indicate a potential for malignant transformation occur...

(This article belongs to the Section Clinical Diagnosis and Prognosis)
  • Article
  • Open Access
1,050 Views
13 Pages

Medical Professionals’ Opinions of and Attitudes Toward Uterus Transplantation in Hungary

  • Kata Szilvia Papp,
  • Peter Szakaly,
  • Szilard Kolumban,
  • Kálmán András Kovács,
  • Jozsef Bodis,
  • Nelli Farkas,
  • Gabor Fazekas and
  • Balint Farkas

25 October 2025

Background: Uterus transplantation (UTx) is a proven treatment for individuals affected by absolute uterine factor infertility (AUFI) who desire biological motherhood. Despite the fact that over 130 procedures have been performed worldwide in the pas...

  • Review
  • Open Access
19 Citations
6,445 Views
13 Pages

Living-Donor Uterus Transplantation: A Clinical Review

  • Massimiliano Veroux,
  • Paolo Scollo,
  • Martina Maria Giambra,
  • Giuseppe Roscitano,
  • Alessia Giaquinta,
  • Francesco Setacci and
  • Pierfrancesco Veroux

29 January 2024

Uterus transplantation (UTx) is currently the only available treatment for absolute uterine factor infertility. More than 90 uterus transplantations have been performed worldwide, mostly from living donors. Living-donor (LD) UTx is a challenging surg...

(This article belongs to the Special Issue New Advances in Uterus and Ovarian Transplantation)
  • Review
  • Open Access
12 Citations
4,158 Views
10 Pages

Deceased Donor Uterus Transplantation: A Narrative Review of the First 24 Published Cases

  • Basilio Pecorino,
  • Giuseppe Scibilia,
  • Martina Ferrara,
  • Pierfrancesco Veroux,
  • Benito Chiofalo and
  • Paolo Scollo

19 August 2024

Uterus transplantation is the surgical treatment for absolute uterine factor infertility (AUFI), a congenital or acquired condition characterized by the absence of a uterus. More than 80 transplants have been performed worldwide, resulting in more th...

(This article belongs to the Section Obstetrics and Gynecology)