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20 Results Found

  • Feature Paper
  • Article
  • Open Access
5 Citations
3,176 Views
11 Pages

1 July 2020

An essential input of annuity pricing is the future retiree mortality. From observed age-specific mortality data, modeling and forecasting can take place in two routes. On the one hand, we can first truncate the available data to retiree ages and the...

  • Article
  • Open Access
2 Citations
1,570 Views
11 Pages

The Role of Lymph-Adipose Crosstalk in Alcohol-Induced Perilymphatic Adipose Tissue Dysfunction

  • Kourtney D. Weaver,
  • Liz Simon,
  • Patricia E. Molina and
  • Flavia Souza-Smith

8 October 2024

Chronic alcohol use leads to metabolic dysfunction in adipose tissue. The underlying mechanisms and the contribution of alcohol-induced adipose tissue dysfunction to systemic metabolic dysregulation are not well understood. In our previous studies, w...

  • Article
  • Open Access
1 Citations
1,499 Views
26 Pages

Measurement Method of Whole Mechanical Automatic Vertical Drilling Tools

  • Yuxuan Wang,
  • Chaoqun Ma,
  • Kai Zhang and
  • Baolin Liu

14 August 2024

The inaccurate positioning of a plat valve is a crucial factor affecting the efficiency and safety of drilling operations. Because of the complicated structure of vertical drilling, it is difficult to obtain the actual position of a plat valve during...

  • Article
  • Open Access
24 Citations
5,528 Views
16 Pages

30 October 2021

Automatic Number Plate Recognition (ANPR) has been widely used in different domains, such as car park management, traffic management, tolling, and intelligent transport systems. Despite this technology’s importance, the existing ANPR approaches suffe...

  • Feature Paper
  • Article
  • Open Access
2 Citations
5,545 Views
20 Pages

Mapping and Analyzing Stream Network Changes in Watonwan River Watershed, Minnesota, USA

  • Fei Yuan,
  • Phillip Larson,
  • Roman Mulvihill,
  • Devon Libby,
  • Jessica Nelson,
  • Tyler Grupa and
  • Rick Moore

Much of the Watonwan River tributary system to the upper Mississippi River basin (UMR), and the fluvial systems to which it drains, are listed as impaired under the United States Environmental Protection Agency Clean Water Act303(d) and/or by the Min...

  • Feature Paper
  • Article
  • Open Access
282 Views
14 Pages

26 December 2025

In this study, we propose a minimal reaction system for the Hippo–YAP/TAZ pathway that explicitly includes inactive LATS, active pLATS, cytoplasmic and nuclear YAP/TAZ, and phosphorylated YAP/TAZ. Local cell density is incorporated into the LAT...

  • Article
  • Open Access
8 Citations
2,956 Views
16 Pages

29 October 2022

The luteinizing hormone (LH) and maturation-inducing steroids (MIS), such as 17α,20β-dihydroxy-4-pregnen-3-one, regulate the final oocyte maturation in teleosts. Oocyte maturational competence (OMC) and ovulatory competence measure the sen...

  • Article
  • Open Access
8 Citations
3,079 Views
19 Pages

25 June 2018

Along with massive applications of power electronic equipment and non-linear loads, harmonic pollutions are becoming more serious than ever. This paper describes a novel electromagnetic coupling reactor based passive power filter with dynamic tuning...

  • Article
  • Open Access
29 Citations
3,748 Views
19 Pages

The Influence of the Gradient Infill of PLA Samples Produced with the FDM Technique on Their Mechanical Properties

  • Joanna Maszybrocka,
  • Michał Dworak,
  • Grażyna Nowakowska,
  • Patrycja Osak and
  • Bożena Łosiewicz

10 February 2022

Three-dimensional printing is a dynamically developing field of industry. Its main advantage is the small amount of waste, no need to use specialized tools, and easy control of the mechanical properties of the printed model. One of the most popular t...

  • Article
  • Open Access
2,951 Views
20 Pages

31 August 2020

Rotor stator interaction (RSI) is an important phenomenon influencing performances in the pump, turbine, and compressor. In this paper, the correlation-based transition model is used to study the RSI phenomenon between a translational cascade of airf...

  • Article
  • Open Access
2 Citations
5,415 Views
22 Pages

Identification of Prominent Genes between 3D Glioblastoma Models and Clinical Samples via GEO/TCGA/CGGA Data Analysis

  • Brandon Wee Siang Phon,
  • Saatheeyavaane Bhuvanendran,
  • Qasim Ayub,
  • Ammu Kutty Radhakrishnan and
  • Muhamad Noor Alfarizal Kamarudin

25 April 2023

A paradigm shift in preclinical evaluations of new anticancer GBM drugs should occur in favour of 3D cultures. This study leveraged the vast genomic data banks to investigate the suitability of 3D cultures as cell-based models for GBM. We hypothesise...

  • Article
  • Open Access
2 Citations
5,275 Views
25 Pages

Development of a Chicken Gastrointestinal Tract (GIT) Simulation Model: Impact of Cecal Inoculum Storage Preservation Conditions

  • Nelson Mota de Carvalho,
  • Célia Maria Costa,
  • Cláudia Castro,
  • Mayra Anton Dib Saleh,
  • Manuela Estevez Pintado,
  • Diana Luazi Oliveira and
  • Ana Raquel Madureira

A chicken gastrointestinal tract (GIT) simulation model was developed to help predict the potential effects of feed additives supplementation on chicken’ microbiota. The chemical and enzymatic conditions for oral, gastric, intestinal, and cecum...

  • Article
  • Open Access
22 Citations
2,515 Views
20 Pages

31 October 2022

In recent times, heat and mass transportation have had some of the most recognized and attractive research areas in computational fluid dynamics. It is useful in the modeling of the flow of nuclear reactors, bioinformatics, the medical discipline, et...

  • Article
  • Open Access
14 Citations
4,847 Views
13 Pages

Deformation of Emulsion Droplet with Clean and Particle-Covered Interface under an Electric Field

  • Muhammad Salman Abbasi,
  • Haroon Farooq,
  • Hassan Ali,
  • Ali Hussain Kazim,
  • Rabia Nazir,
  • Aqsa Shabbir,
  • Seongsu Cho,
  • Ryungeun Song and
  • Jinkee Lee

4 July 2020

The electrohydrodynamic deformation of an emulsion droplet with a clean and particle-covered interface was explored. Here, the electrohydrodynamic deformation was numerically and experimentally demonstrated under the stimuli of moderate and strong el...

  • Article
  • Open Access
8 Citations
3,626 Views
25 Pages

Targeting PARP-1 and DNA Damage Response Defects in Colorectal Cancer Chemotherapy with Established and Novel PARP Inhibitors

  • Philipp Demuth,
  • Lea Thibol,
  • Anna Lemsch,
  • Felix Potlitz,
  • Lukas Schulig,
  • Christoph Grathwol,
  • Georg Manolikakes,
  • Dennis Schade,
  • Vassilis Roukos and
  • Jörg Fahrer
  • + 1 author

10 October 2024

The DNA repair protein PARP-1 emerged as a valuable target in the treatment of tumor entities with deficiencies of BRCA1/2, such as breast cancer. More recently, the application of PARP inhibitors (PARPi) such as olaparib has been expanded to other c...

  • Article
  • Open Access
1 Citations
665 Views
18 Pages

7 October 2025

Background/Objectives: Growing evidence implicates that processes mediated by cytokines, growth factors, and the plasminogen activation (PA) system play crucial roles in the pathogenesis of epilepsy and its comorbidities. Methods: This study was carr...

  • Article
  • Open Access
3 Citations
1,971 Views
18 Pages

Miniaturization and Model-Integration of the Optical Measurement System for Temperature-Sensitive Paint Investigations

  • Jonathan Lemarechal,
  • Benjamin Daniel Dimond,
  • Hans Peter Barth,
  • Michael Hilfer and
  • Christian Klein

10 August 2023

The temperature-sensitive paint (TSP) method, an optical measurement technique, is used for qualitative skin friction visualizations in a wide variety of aerodynamic applications. One such application is the visualization of the laminar–turbule...

  • Article
  • Open Access
3,095 Views
16 Pages

Transcriptomics of Congenital Hepatic Fibrosis in Autosomal Recessive Polycystic Kidney Disease Using PCK Rats

  • Satyajeet Khare,
  • Lu Jiang,
  • Diego Paine-Cabrera,
  • Udayan Apte and
  • Michele T. Pritchard

21 July 2023

Congenital hepatic fibrosis/Autosomal recessive polycystic kidney disease (CHF/ARPKD) is an inherited neonatal disease induced by mutations in the PKHD1 gene and characterized by cysts and robust pericystic fibrosis in the liver and kidneys. The PCK...

  • Article
  • Open Access
478 Views
17 Pages

SAUCF: A Framework for Secure, Natural-Language-Guided UAS Control

  • Nihar Shah,
  • Varun Aggarwal and
  • Dharmendra Saraswat

14 December 2025

Precision agriculture increasingly recognizes the transformative potential of unmanned aerial systems (UASs) for crop monitoring and field assessment, yet research consistently highlights significant usability barriers as the main constraints to wide...