Skip to Content

23 Results Found

  • Review
  • Open Access
13 Citations
3,282 Views
17 Pages

A Review of Distribution and Profiles of HBCD in Different Environmental Media of China

  • Jinglin Deng,
  • Wenbin Liu,
  • Lirong Gao,
  • Tianqi Jia,
  • Yunchen He,
  • Tianao Mao and
  • Javid Hussain

20 December 2023

Hexabromocyclododecane (HBCD) is the most important flame retardant that has been used in Expanded Polystyrene foam and Extruded Polystyrene foam in the past forty years across the world. China was the major producer and user of HBCD, and the total H...

  • Article
  • Open Access
12 Citations
4,705 Views
11 Pages

As one of the most widely used brominated flame retardants, hexabromocyclododecane (HBCD) is found widely in the environmental media. In this study, the content and spatial distribution of HBCD and risk posed by HBCD in surface sediment in the Weihe...

  • Article
  • Open Access
2 Citations
2,689 Views
11 Pages

The sorption of hexabromocyclododecanes (HBCDs) on sediment affects the fate and transport of HBCDs in rivers. The sorption of HBCDs on sediment from the Weihe River was investigated by performing batch equilibration experiments, and the effects of c...

  • Article
  • Open Access
2 Citations
1,789 Views
16 Pages

12 September 2024

Hexabromocyclododecane (HBCD) is widely used in polystyrene foams, building materials, and electrical equipment as a brominated flame retardant (BFR) and persists in the environment and human body matrix. It has attracted increased attention since it...

  • Review
  • Open Access
14 Citations
3,664 Views
12 Pages

Bioaccumulation and Biomagnification of Hexabromocyclododecane in Marine Biota from China: A Review

  • Ying Zhang,
  • Sijia Li,
  • Yafeng Zhang,
  • Yezi Chen,
  • Xutao Wang and
  • Yuxin Sun

19 October 2022

Hexabromocyclododecane (HBCD) was listed in Annex A of the Stockholm Convention on Persistent Organic Pollutants for its persistence, bioaccumulation and toxicity, and pose significant adverse effects on natural environments and human health. HBCDs a...

  • Feature Paper
  • Review
  • Open Access
36 Citations
5,086 Views
25 Pages

26 April 2023

Hexabromocyclododecane (HBCD) is a non-aromatic compound belonging to the bromine flame retardant family and is a known persistent organic pollutant (POP). This compound accumulates easily in the environment and has a high half-life in water. With a...

  • Article
  • Open Access
5 Citations
3,407 Views
8 Pages

25 November 2021

A gas chromatography-mass spectrometry (GC/MS) method for the determination of hexabromocyclododecane (HBCD) in expanded polystyrene and extruded polystyrene foam (EPS/XPS) was developed. The EPS/XPS samples were ultrasonically extracted with acetone...

  • Article
  • Open Access
11 Citations
2,856 Views
10 Pages

Persistent organic pollutants (POPs), some of the most dangerous chemicals released into the aquatic environment, are distributed worldwide due to their environmental persistence and bioaccumulation. In the study, we investigated p53-related apoptoti...

  • Feature Paper
  • Article
  • Open Access
9 Citations
4,558 Views
13 Pages

Novel Brominated Flame Retardants in Dust from E-Waste-Dismantling Workplace in Central China: Contamination Status and Human Exposure Assessment

  • Xuelin Li,
  • Yu Wang,
  • Wenbin Bai,
  • Qiuyue Zhang,
  • Leicheng Zhao,
  • Zhipeng Cheng,
  • Hongkai Zhu and
  • Hongwen Sun

6 January 2023

Novel brominated flame retardants (NBFRs) have been widely used as alternatives to legacy BFRs. However, information on the contamination status and human exposure risks of electronic waste (e-waste)-derived NBFRs in the e-waste workplace is limited....

  • Article
  • Open Access
7 Citations
3,074 Views
14 Pages

Hyper-Branched Cyclodextrin-Based Polymers as Anticoagulant Agents: In Vitro and In Vivo Studies

  • Yousef Khazaei Monfared,
  • Mohammad Mahmoudian,
  • Gjylije Hoti,
  • Daniel Mihai Bisericaru,
  • Fabrizio Caldera,
  • Roberta Cavalli,
  • Parvin Zakeri-Milani,
  • Adrián Matencio and
  • Francesco Trotta

This study tested the anticoagulant effect of cyclodextrin (CD) hyper-branched-based polymers (HBCD-Pols). These polymers were synthesized and tested for their coagulant characteristics in vitro and in vivo. Due to their polymeric structure and anion...

  • Article
  • Open Access
12 Citations
2,907 Views
16 Pages

Risk Characterization and Benefit–Risk Assessment of Brominated Flame Retardant in Commercially Exploited Freshwater Fishes and Crayfish of Lake Trasimeno, Italy

  • Rossana Roila,
  • Raffaella Branciari,
  • David Ranucci,
  • Arianna Stramenga,
  • Tamara Tavoloni,
  • Tommaso Stecconi,
  • Raffaella Franceschini and
  • Arianna Piersanti

Among brominated flame retardants (BFRs), polybrominateddiphenyl ethers (PBDEs) and hexabromocyclododecanes (HBCDs) were the most widely used in past decades. BFRs not being chemically bonded to polymers means they can easily leach from the products...

  • Article
  • Open Access
36 Citations
5,511 Views
13 Pages

Synergistic Effect of Photocatalytic Degradation of Hexabromocyclododecane in Water by UV/TiO2/persulfate

  • Qiang Li,
  • Lifang Wang,
  • Xuhui Fang,
  • Li Zhang,
  • Jingjiu Li and
  • Hongyong Xie

18 February 2019

In this work, the elimination of hexabromocyclododecane (HBCD) is explored by using photodegradation of the UV/TiO2 system, the UV/potassium persulfate (KPS) system, and the homo/heterogeneous UV/TiO2/KPS system. The experimental results show that th...

  • Communication
  • Open Access
4 Citations
4,304 Views
9 Pages

A modified QuEChERS (quick, easy, cheap, effective, rugged, and safe) sample preparation method coupled with liquid chromatography–tandem mass spectrometry (LC–MS/MS) was proposed for the determination of α-, β-, and γ-he...

  • Article
  • Open Access
3 Citations
3,194 Views
14 Pages

Does Better Post-Thaw Motility of Dog Sperm Frozen with CLC Mean Better Zona Pellucida Binding Ability?

  • Zuzanna Ligocka,
  • Agnieszka Partyka,
  • Sabine Schäfer-Somi,
  • Anna Mucha and
  • Wojciech Niżański

9 May 2023

Even though the search for methods improving cryopreservation of canine spermatozoa led to an improvement of post-thaw quality, fertilizing results after insemination with frozen–thawed semen are still not satisfying. In this study, we focused...

  • Article
  • Open Access
49 Citations
8,388 Views
13 Pages

Evaluation of Common Use Brominated Flame Retardant (BFR) Toxicity Using a Zebrafish Embryo Model

  • Crystal Y. Usenko,
  • Erika L. Abel,
  • Aaron Hopkins,
  • Gerardo Martinez,
  • Jonathan Tijerina,
  • Molly Kudela,
  • Nick Norris,
  • Lana Joudeh and
  • Erica D. Bruce

2 September 2016

Brominated flame retardants (BFRs) are used to reduce the flammability of plastics, textiles, and electronics. BFRs vary in their chemical properties and structures, and it is expected that these differences alter their biological interactions and to...

  • Article
  • Open Access
1 Citations
271 Views
28 Pages

21 February 2026

Mosses (Bryophyta) are well-established biomonitors of atmospheric deposition, including persistent organic pollutants (POPs) and microplastics (MPs). Using German Moss Survey 2020 data, this study identified factors influencing POPs and MPs in mosse...

  • Review
  • Open Access
3 Citations
2,015 Views
16 Pages

The escalating concern over environmental pollutants, particularly brominated flame retardants (BFRs), demands sophisticated detection methodologies for compounds like Tetrabromobisphenol A (TBBPA) and Hexabromocyclododecane (HBCD). Amidst these chal...

  • Article
  • Open Access
1 Citations
571 Views
15 Pages

25 November 2025

Rubber tree (Hevea brasiliensis) is a crucial economic crop in tropical regions worldwide; however, low temperature in some areas have become a major source of abiotic stress that constrains the sustainable development of the natural rubber industry....

  • Article
  • Open Access
1 Citations
2,272 Views
11 Pages

Hybrid lateral closed-wedge high tibial osteotomy (HBHTO) carries certain advantages over medial open-wedge high tibial osteotomy (OWHTO). We investigated the potential difference in the required correction angle between HBHTO and OWHTO to achieve an...

  • Article
  • Open Access
229 Views
31 Pages

28 February 2026

Persistent organic pollutants (POPs) are globally distributed toxic contaminants. Since 1990, mosses have been used in the UNECE European Moss Survey as cost-effective biomonitors of atmospheric deposition. This study provides the first predictive ma...

  • Article
  • Open Access
34 Citations
5,657 Views
16 Pages

Oncogenic Potential of Bisphenol A and Common Environmental Contaminants in Human Mammary Epithelial Cells

  • Vidhya A Nair,
  • Satu Valo,
  • Päivi Peltomäki,
  • Khuloud Bajbouj and
  • Wael M. Abdel-Rahman

There is an ample epidemiological evidence to support the role of environmental contaminants such as bisphenol A (BPA) in breast cancer development but the molecular mechanisms of their action are still not fully understood. Therefore, we sought to a...

  • Article
  • Open Access
13 Citations
4,037 Views
22 Pages

Transcriptomic Analysis of the Differential Nephrotoxicity of Diverse Brominated Flame Retardants in Rat and Human Renal Cells

  • Lillie Marie A. Barnett,
  • Naomi E. Kramer,
  • Amanda N. Buerger,
  • Deirdre H. Love,
  • Joseph H. Bisesi and
  • Brian S. Cummings

17 September 2021

Brominated flame retardants (BFRs) are environmentally persistent, are detected in humans, and some have been banned due to their potential toxicity. BFRs are developmental neurotoxicants and endocrine disruptors; however, few studies have explored t...

  • Article
  • Open Access
9 Citations
4,582 Views
16 Pages

Role of Persistent Organic Pollutants in Breast Cancer Progression and Identification of Estrogen Receptor Alpha Inhibitors Using In-Silico Mining and Drug-Drug Interaction Network Approaches

  • Bibi Zainab,
  • Zainab Ayaz,
  • Umer Rashid,
  • Dunia A. Al Farraj,
  • Roua M. Alkufeidy,
  • Fatmah S. AlQahtany,
  • Reem M. Aljowaie and
  • Arshad Mehmood Abbasi

19 July 2021

The strong association between POPs and breast cancer in humans has been suggested in various epidemiological studies. However, the interaction of POPs with the ERα protein of breast cancer, and identification of natural and synthetic compounds to in...