Special Issues

Viruses publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Viral Diseases of Domestic Animals
edited by
submission deadline 15 Aug 2025 | 3 articles | Viewed by 2728 | Submission Open
Keywords: viral diseases; emerging infections; domestic animals; epidemiology; pathogenesis
(This special issue belongs to the Section Animal Viruses)
Swine Viruses: Immunology and Vaccinology
edited by and
submission deadline 15 Aug 2025 | Viewed by 299 | Submission Open
Keywords: swine virology; swine immunology; vaccine development; vaccinology; viral pathogenesis; vaccine design; disease prevention; swine health
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Broadly Protective Anti-Viral Vaccines 2025
edited by
submission deadline 29 Aug 2025 | 1 articles | Viewed by 1445 | Submission Open
Keywords: universal vaccines; structure-based rational design; cross-protection; broadly neutralizing antibody; T-cell epitopes; preventative and therapeutic vaccines; adaptive immunology; highly variable virus
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Antiviral Resistance Mutations submission deadline 31 Aug 2025 | 8 articles | Viewed by 14183 | Submission Open
Keywords: antiviral resistance; virus evolution; viral genome mutation; drug-resistant phenotypes; immune escape
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Hepatitis E: Molecular Virology, Pathogenesis, and Treatment, 2nd Edition
edited by
submission deadline 31 Aug 2025 | 7 articles | Viewed by 8295 | Submission Open
Keywords: HEV; HEV life cycle; HEV genotypes; model systems; zoonosis; pathogenesis; HEV– host interations; antivirals
(This special issue belongs to the Section Human Virology and Viral Diseases)
Emerging and Reemerging Plant Viruses in a Changing World submission deadline 31 Aug 2025 | 6 articles | Viewed by 6707 | Submission Open
Keywords: emerging and re-emerging viruses; virus spillover; climate change and global trade; mixed infections; plant– virus– vector relationships
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Aquatic Animal Viruses and Antiviral Immunity
edited by
submission deadline 31 Aug 2025 | 8 articles | Viewed by 6223 | Submission Open
Keywords: aquatic virus; aquatic animals; innate immunity; adaptive immunity; host– virus interactions; fish; aquaculture; biomedical research; aquatic animal stewardship
(This special issue belongs to the Section Animal Viruses)
Viral Infections in Gynecological Diseases
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 3935 | Submission Open
Keywords: herpes viruses; rubella virus; hepatitis viruses; parvovirus B19; HIV; HPV; Zika virus; placenta; gynecology; cancer
(This special issue belongs to the Section Human Virology and Viral Diseases)
Natural, Semisynthetic, and Synthetic Antiviral Drugs Targeting HIV and SARS-CoV-2 submission deadline 31 Aug 2025 | 3 articles | Viewed by 3657 | Submission Open
Keywords: antiviral design and discovery; natural product screening; natural products as a scaffold for semisynthetic antivirals; repurposing drugs; high-throughput screening; antiviral resistance; biophysical characterization of the interaction between antivirals and targets; combination of light and photosensitizers in antiviral discovery; cell-based and in vivo assays; in silico calculations
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Beyond Acute: Navigating Long COVID and Post-Viral Complications
edited by Maggie Bartlett, Janko Nikolich-Žugich, Rubeshan Perumal and Anders Vahlne
submission deadline 31 Aug 2025 | 2 articles | Viewed by 3418 | Submission Open
Keywords: long COVID; post-viral complications; dysregulated immune responses; neurological complications; respiratory complications; cardiovascular complications; pregnancy-related complications
(This special issue belongs to the Section Human Virology and Viral Diseases)
Arboviruses and Global Health: A PanDengue Net Initiative
edited by and Jorge Osorio
submission deadline 31 Aug 2025 | 3 articles | Viewed by 3180 | Submission Open
Keywords: dengue; zika; chikungunya; mayaro; aedes; immunology; pathogenesis; vector control
(This special issue belongs to the Section General Virology)
Antiviral Agents to Influenza Virus 2025
edited by Wu Zhong and
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2976 | Submission Open
Keywords: influenza; antiviral drug; drug resistance; antiviral drug target
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Viral Mechanisms of Immune Evasion
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 2512 | Submission Open
Keywords: immune evasion; virulent factor; antiviral signaling; pathogenesis; antiviral strategy
(This special issue belongs to the Section General Virology)
Pathogenesis of Flavivirus Infections
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2310 | Submission Open
Keywords: pathogenesis; immunopathogenesis; immune response; clinical outcomes; vaccines; diagnostic; public health; one health; molecular biology; flavivirus; computer simulation; artificial intelligence
(This special issue belongs to the Section General Virology)
Influenza and Other Respiratory Viruses: Prevention, Diagnosis, Treatment: 2nd Edition
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 2218 | Submission Open
Keywords: influenza; adenovirus; coronoavirus; respiratory syncytial virus; rhinovirus; respiratory virus; antiviral strategies; epidemiology; diagnosis; treatment; vaccination; surveillance; vaccine development
(This special issue belongs to the Section Animal Viruses)
Rodent-Borne Viruses 2025 submission deadline 31 Aug 2025 | 1 articles | Viewed by 1838 | Submission Open
Keywords: rodent-borne viruses; hantaviridae; arenaviridae; poxviridae; zoonosis; virus ecology and evolution; virus– host interaction; virus discovery; animal model; rodents
(This special issue belongs to the Section Animal Viruses)
Bovine Viral Diarrhea Viruses and Other Pestiviruses
edited by
submission deadline 31 Aug 2025 | 3 articles | Viewed by 1751 | Submission Open
Keywords: epidemiological survey; prevalence; seroprevalence; bovine viral diarrhoea; mucosal disease; neutralizing antibodies; taxonomy; antiviral drugs; vaccines; species and subgenotypes; wild animal
(This special issue belongs to the Section Animal Viruses)
Roles of Macrophages in Viral Infections, 2nd Edition
edited by
submission deadline 31 Aug 2025 | 2 articles | Viewed by 1372 | Submission Open
Keywords: macrophage; microglia; Kupffer cells; viral infection; antiviral immunity; inflammatory cytokines; langerhans cell; antiviral drugs; viral pathogenesis
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Citrus Viral Diseases: Advances in Knowledge and Technologies and Their Containment Measures
edited by , and Moshe Bar-Joseph
submission deadline 31 Aug 2025 | 1 articles | Viewed by 950 | Submission Open
Keywords: citrus viruses; genomic characterization; diagnostics; vector; virus– insect interactions; viral and virus-like pathogens
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Herpesvirus Transcriptional Control
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 711 | Submission Open
Keywords: herpes simplex virus; herpesvirus gene expression; viral latency and reactivation; virus– host interactions
(This special issue belongs to the Section Animal Viruses)
HIV and Viral Hepatitis Co-Infection submission deadline 31 Aug 2025 | 1 articles | Viewed by 679 | Submission Open
Keywords: HIV; hepatitis A; hepatitis B; hepatitis C; hepatitis delta; hepatitis E; co-infection; antiviral therapy
(This special issue belongs to the Section Human Virology and Viral Diseases)
Early Diagnosis and Surveillance of Transboundary and Emerging Viral Diseases of Animals, 2nd Edition submission deadline 31 Aug 2025 | 1 articles | Viewed by 648 | Submission Open
Keywords: diagnostics; surveillance; transboundary; emerging; animal diseases; virus; detection; validation; novel; sample types; alternative
(This special issue belongs to the Section Animal Viruses)
Animal Models in Emerging/Re-Emerging Infectious Diseases
edited by Dong Yang
submission deadline 31 Aug 2025 | 1 articles | Viewed by 633 | Submission Open
Keywords: emerging/re-emerging infectious diseases; animal models; pathogen– host interactions; pathogenesis; interventions; drugs; vaccines
(This special issue belongs to the Section Animal Viruses)
Applications of Baculoviruses: Expression Factories, Vaccines and VLPs, Gene Delivery Vectors, and Virus Genetics Models submission deadline 31 Aug 2025 | 1 articles | Viewed by 628 | Submission Open
Keywords: baculovirus; baculovirus– host cell interactions; baculovirus genetic diversity; baculovirus expression; baculovirus technology applications  
(This special issue belongs to the Section Invertebrate Viruses)
Cyanophage and Algal Virus submission deadline 31 Aug 2025 | Viewed by 559 | Submission Open
Keywords: cyanophages; algal viruses; Algavirales; Phycodnaviridae; Marnaviridae; aquatic virus; algae bloom; viral diversity; viral ecology
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Emerging and Re-Emerging Zoonotic Viruses: Current Challenges in Vaccinology
edited by Gema Lorenzo and Sandra Moreno
submission deadline 31 Aug 2025 | Viewed by 482 | Submission Open
Keywords: emerging zoonotic viruses; re-emerging zoonotic viruses; vaccine development; viral vector; reverse genetics systems
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Advances in Honey Bee Viruses Research
edited by and Kerstin Seitz
submission deadline 31 Aug 2025 | Viewed by 400 | Submission Open
Keywords: honey bee viruses; deformed wing virus; DWV; sacbrood virus; SBV; chronic bee paralysis virus; CBPV; acute bee paralysis virus; ABPV; Israel acute bee paralysis virus; IAPV; Iflavirus; Dicistrovirus; rhabdovirus; ARV
(This special issue belongs to the Section Invertebrate Viruses)
Molecular and Biological Virus-Plant-Insect Vector Interactions
edited by Yong Liu
submission deadline 31 Aug 2025 | Viewed by 357 | Submission Open
Keywords: plant virus transmission; virus– plant interactions; virus– vector interactions; virus– vector– plant interactions; epidemiology of virus transmission; molecular mechanisms; viral manipulation; diagnostic techniques
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Lytic Cycle of Herpesviruses and the Associated Pathogenesis
edited by Junjie Zhang, and Tingting Li
submission deadline 31 Aug 2025 | Viewed by 293 | Submission Open
Keywords: herpesviruses; innate immune responses; life cycle; herpesvirus– host interactions; pathogenesis
(This special issue belongs to the Section Human Virology and Viral Diseases)
Navigating Viral Threats: Enteric and Respiratory Viral Challenges in the Post-COVID-19 Era
edited by Ahmed Mostafa and Abdou Allayeh
submission deadline 31 Aug 2025 | Viewed by 265 | Submission Open
Keywords: enteric viruses; respiratory viruses; human influenza viruses; COVID-19; avian influenza viruses; surveillance; virus epidemiology; viral diagnosis
(This special issue belongs to the Section Human Virology and Viral Diseases)
Virus Polyproteins and Polyprotein Processing
edited by Martin Denis Ryan
submission deadline 31 Aug 2025 | Viewed by 197 | Submission Open
Keywords: virus polyproteins; polyprotein processing; translation
(This special issue belongs to the Section General Virology)
Translational Research in Virology submission deadline 31 Aug 2025 | Viewed by 195 | Submission Open
Keywords: vaccines; antiviral drugs; monoclonal antibodies; viral vectors; self-amplifying RNA; clinical trials; translational medicine; proteomic analysis; antiviral resistance; bioinformatics; structural virology; immune escape mechanisms; viral evolution; diagnostic virology; high-throughput screening; nanotechnology in virology; viral assembly and disassembly; host-pathogen interactions; emerging viral infections
(This special issue belongs to the Section Human Virology and Viral Diseases)
Innovative Prophylactic and Therapeutics for the Treatment of Coronavirus Infection
edited by and Jun-Gyu Park
submission deadline 31 Aug 2025 | Viewed by 160 | Submission Open
Keywords: prophylactic; therapeutics; SARS-CoV-2; viral variants; antivirals
(This special issue belongs to the Section Coronaviruses)
Host-Mediated Viral Mutations: APOBECs, ADARs, and Beyond
edited by
submission deadline 1 Sep 2025 | 3 articles | Viewed by 2939 | Submission Open
Keywords: cytosine and adenosine deamination; methylcytosine; epigenetics; mutagenesis; cancer; APOBEC antagonists; ADAR; DNA damage response; innate immunity; adaptive immunity; virus selection
(This special issue belongs to the Section Human Virology and Viral Diseases)
Human and Animal Papillomavirus: Infections, Genetics, and Vaccines submission deadline 10 Sep 2025 | 7 articles | Viewed by 10608 | Submission Open
Keywords: vaccines; infection biology; genetics; molecular epidemiology; bioinformatics; oncogenesis; HPV and nongenital cancer; HPV and cancer; animal papillomavirus and associated diseases
(This special issue belongs to the Section Human Virology and Viral Diseases)
HIV and HTLV Infections and Coinfections submission deadline 30 Sep 2025 | 10 articles | Viewed by 16585 | Submission Open
Keywords: human T-cell leukemia virus; HIV; HTLV-associated diseases; HIV co-infections
(This special issue belongs to the Section Human Virology and Viral Diseases)
Recent Advances in Antiviral Natural Products 2025 submission deadline 30 Sep 2025 | 5 articles | Viewed by 14256 | Submission Open
Keywords: virus; antiviral; host-defense; natural product; drug delivery; infectious disease
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Viral Infections and Immune Dysregulation 2024–2025 submission deadline 30 Sep 2025 | 4 articles | Viewed by 11834 | Submission Open
Keywords: immune responses; immune dysregulation; autoimmunity; viral infections; immunomodulation
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Host Cell-Virus Interaction, 4th Edition submission deadline 30 Sep 2025 | 6 articles | Viewed by 9500 | Submission Open
Keywords: virus; viral proteins; virus entry; viral replication and pathogenesis; virus assembly and egress; intracellular trafficking of virus; host cell; cellular signaling; interferon pathway; inflammasome; viral immune evasion; immune response; cell death; apoptosis; autophagy; host-virus interaction; anti-viral strategies; direct acting antivirals; broad-spectrum antiviral agents; RNAi; microRNAs; neutralizing antibodies; molecular mechanisms of antivirals; molecular mechanisms of drug-resistance
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Insect Viruses and Pest Management, the Third Edition submission deadline 30 Sep 2025 | 8 articles | Viewed by 8636 | Submission Open
Keywords: insect-specific viruses; pest control; virus-based biocontrol agents; quality control; industrial production; resistance development to virus-based biocontrol agents
(This special issue belongs to the Section Invertebrate Viruses)
JC Polyomavirus
edited by and Anne-Sophie L'Honneur
submission deadline 30 Sep 2025 | 3 articles | Viewed by 5059 | Submission Open
Keywords: JC polyomavirus; progressive multifocal leukoencephalopathy (PML); neurotropic variants; viral genomic rearrangements
(This special issue belongs to the Section Human Virology and Viral Diseases)
Computational Biology of Viruses: From Molecules to Epidemics, Volume 2
edited by
submission deadline 30 Sep 2025 | 4 articles | Viewed by 4609 | Submission Open
Keywords: mathematical modeling; simulation modeling; molecular processes; within-host dynamics; epidemiological models; multiscale models
(This special issue belongs to the Section General Virology)
Coronaviruses Pathogenesis, Immunity, and Antivirals (2nd Edition)
edited by and Fei Yu
submission deadline 30 Sep 2025 | 4 articles | Viewed by 2803 | Submission Open
Keywords: coronavirus; pathogenesis; molecular; vaccines; evolution; immunity; antivirals
(This special issue belongs to the Section Coronaviruses)
Viral Diseases of Livestock and Diagnostics, 2nd Edition
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 2034 | Submission Open
Keywords: viral disease; zoonosis; zooanthroponosis; production animal
(This special issue belongs to the Section Animal Viruses)
Mechanisms of Herpesvirus Resistance
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1971 | Submission Open
Keywords: human herpesviruses; cytomegalovirus; drug resistance; antiviral agents; immunocompromised host; novel anti-herpesvirus therapies; DNA polymerase; terminase
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Dual Nature of Bacteriophages: Friends or Enemies in Food Industry? submission deadline 30 Sep 2025 | 3 articles | Viewed by 1940 | Submission Open
Keywords: bacteriophages; biocontrol; biosensors; food safety; foodborne bacterial pathogens; food quality; foodborne sapro-phytic bacteria
(This special issue belongs to the Section Bacterial Viruses)
Mechanism of Receptor Recognition in Coronavirus, 2nd Edition
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 1853 | Submission Open
Keywords: receptor recognition; spike protein adaptations; receptor-binding domain (RBD); host range and zoonotic transmission; viral evolution and immune evasion; glycosylation and co-receptors; proteolytic activation; therapeutic and vaccine strategies; cross-species viral transmission; pandemic preparedness and surveillance
(This special issue belongs to the Section Animal Viruses)
Application of Plant Viruses in Biotechnology submission deadline 30 Sep 2025 | 1 articles | Viewed by 1777 | Submission Open
Keywords: plant viruses; viral nanoparticles; plant viral vectors; biotechnological applications
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Diversity and Evolution of Viruses in Ecosystem 2025
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 1767 | Submission Open
Keywords: environmental virology; viral metagenomics; viral metatranscriptomics; phage genomics; virus evolution and phylogeny
(This special issue belongs to the Section General Virology)
Animal Herpesvirus 2025
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 1267 | Submission Open
Keywords: herpesviruses; innate immune responses; host adaptive immune responses; herpesvirus-host; interactions; susceptibility
(This special issue belongs to the Section Animal Viruses)
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