Veterinary Virology and One Health

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Animal Viruses".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 877

Special Issue Editors


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Guest Editor
Department of Infectious Diseases and Microbiology, University of Pittsburgh School of Public Health, Pittsburgh, PA 15261, USA
Interests: emerging and zoonotic viruses; mechanisms of spillover; virus–host interactions; viral diagnostics and interventions
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA
Interests: emerging and zoonotic viruses; understanding inter-species spillover; virus–host interactions; developing novel vaccines; developing serological surveillance tools
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Viral infections in animals are not only a concern for veterinary medicine; they pose substantial risks to public health through zoonotic transmission. More than 60% of infectious diseases in humans are transmitted from animals. Emerging zoonotic viruses such as SARS-CoV-2, influenza A virus H5N1, Ebola virus, and henipaviruses underscore the need to embrace veterinary virology as an integral component of One Health. Surveillance of viruses in domestic and wildlife species to detect their potential to infect humans will provide early warning for public health before the emergence of outbreak- or pandemic-potential viruses.

This Special Issue brings together articles that explore various aspects of emerging zoonotic viruses within the One Health framework. We invite contributions on topics including emerging viruses, surveillance in wild and domestic species, the impact of climate change events on virus emergence and transmission, virus evolution, zoonotic spillover prediction, advancements in diagnostics and vaccines, and case studies on successful One Health collaborations.

Prof. Dr. Suresh Varma Kuchipudi
Dr. Santhamani Ramasamy
Guest Editors

Manuscript Submission Information

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Keywords

  • emergence
  • spillover
  • zoonotic virus
  • One Health
  • interspecies transmission
  • evolution

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Published Papers (1 paper)

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Research

18 pages, 3638 KB  
Article
Glycyrrhizic Acid-Modified Gold Nanoparticles Show Inhibitory Activity Against PRRSV and SARS-CoV-2 Pseudovirus In Vitro
by Ting Tong, Xiaotong Zhang, Yating Lei, Linjie Li, Shaobo Xiao and Jiangong Liang
Viruses 2026, 18(4), 454; https://doi.org/10.3390/v18040454 - 9 Apr 2026
Viewed by 458
Abstract
The development of novel antiviral nanomaterials is an important approach for addressing emerging viral threats. In this study, glycyrrhizic acid-modified gold nanoparticles (GA-Au NPs) were successfully synthesized and characterized, and their inhibitory effects against porcine reproductive and respiratory syndrome virus (PRRSV) and severe [...] Read more.
The development of novel antiviral nanomaterials is an important approach for addressing emerging viral threats. In this study, glycyrrhizic acid-modified gold nanoparticles (GA-Au NPs) were successfully synthesized and characterized, and their inhibitory effects against porcine reproductive and respiratory syndrome virus (PRRSV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pseudovirus were systematically evaluated. At non-cytotoxic concentrations, GA-Au NPs showed inhibitory activity against PRRSV in vitro. Stage-specific assays suggested that intracellular replication-related events were prominently affected, with additional inhibitory effects observed during adsorption, invasion, and release, whereas no direct virucidal activity was detected under the tested conditions. Furthermore, GA-Au NPs dose-dependently reduced SARS-CoV-2 pseudovirus infection-associated reporter signals in HEK-293T-ACE2 cells, supporting inhibitory activity in an additional viral model. In conclusion, GA-Au NPs represent a biocompatible antiviral nanomaterial with multi-stage inhibitory activity against PRRSV and inhibitory effects in a SARS-CoV-2 pseudovirus model, supporting their further evaluation as antiviral nanomaterials in enveloped virus-related models. Full article
(This article belongs to the Special Issue Veterinary Virology and One Health)
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