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Viruses publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Veterinary Virology: Unraveling Host–Pathogen Interactions for Animal Health

edited by

Muhammad Jasim Uddin

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2598 | Submission Open

Keywords: veterinary virology; host– pathogen interactions; viral replication and immune evasion; zoonotic viruses; One Health; vaccine and therapeutic development; molecular virology and genomics; emerging and re-emerging viral pathogens or diseases; animal health and welfare; high-throughput or deep sequencing; outbreak prevention and control; food security

(This special issue belongs to the Section Animal Viruses)

Coronavirus Therapy: Antiviral Drugs and Anti-Inflammatory Immunopharmacology

edited by

Chengyuan Liang

Lei Tian

and

Mengzhou Wang

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2221 | Submission Open

Keywords: coronavirus therapeutics; antiviral target; host-directed antivirals; immunomodulation; diagnostics; prevention; antiviral resistance; AI-driven drug discovery

(This special issue belongs to the Section Coronaviruses)

The Entry and Fusion of Enveloped Virus

edited by

Tsutomu Murakami

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1951 | Submission Open

Keywords: enveloped virus; entry; attachment; virus binding; membrane fusion; internalization; endocytosis; uncoating; intracellular trafficking; nuclear import; receptor; carbohydrates; antiviral; neutralizing antibody; vaccine

(This special issue belongs to the Section General Virology)

Coronaviruses: Variants, Antivirals, and Vaccination

edited by

Cheng-Wen Lin

submission deadline 30 Sep 2026 | 1 articles | Viewed by 970 | Submission Open

Keywords: coronavirus variants; SARS-CoV-2 evolution; antivirals; vaccination; immune response; global health; viral pathogenesis; public health preparedness; host genomics; monoclonal antibodies

(This special issue belongs to the Section Coronaviruses)

3D Models in Viral Pathogenesis

edited by

David C. Bloom

Leonardo D'Aiuto

and Elizabeth Fortunato

submission deadline 30 Sep 2026 | 1 articles | Viewed by 863 | Submission Open

Keywords: organoids; viral pathogenesis; mini-brains; 3D culture; viruses; in vitro models

(This special issue belongs to the Section General Virology)

Immune Evasion and Viral Carcinogenesis

edited by

Christoph Weigel

and Tuan L. Phan

submission deadline 30 Sep 2026 | Viewed by 302 | Submission Open

Keywords: viral oncogenesis; viral carcinogenesis; immune evasion; immune surveillance; oncogenic viruses; immunosuppression; host-pathogen interactions

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Unraveling Human Herpesviruses: From Molecular Mechanisms to Antiviral Approaches

edited by

Christopher B. Whitehurst

submission deadline 30 Sep 2026 | Viewed by 275 | Submission Open

Keywords: human herpesviruses; post-translational modifications; epigenetics; cancer; molecular mechanisms; antivirals; protein interactions

(This special issue belongs to the Section Human Virology and Viral Diseases)

Alphavirus Structural Dynamics and Host–Cell Entry: Structure-Guided Therapeutic and Vaccine Development

edited by

Qibin Geng

submission deadline 30 Sep 2026 | Viewed by 255 | Submission Open

Keywords: alphavirus virion architecture; cryo-EM/cryo-ET; E1/E2 glycoproteins; receptor recognition and tropism; membrane fusion; structural dynamics; nsP replication complexes; structure-guided antiviral discovery; neutralizing antibodies/nanobodies; alphavirus-induced arthritis

(This special issue belongs to the Section Animal Viruses)

Viruses Associated with Gastroenteritis: 2nd Edition

edited by

Celso Cunha

and

Claudia Istrate

submission deadline 30 Sep 2026 | Viewed by 246 | Submission Open

Keywords: vaccines; therapeutic approaches; virus replication; molecular epidemiology; immune response; microbiome; diagnosis

(This special issue belongs to the Section Human Virology and Viral Diseases)

Viral Immunogenicity and Design of Vaccines

edited by Wei Cheng

submission deadline 30 Sep 2026 | Viewed by 232 | Submission Open

Keywords: virus; immunogenicity; antibody response; T cells; B cells; innate receptor; toll-like receptor

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Innate Immune Sensing of Viruses

edited by Zi Li

submission deadline 30 Sep 2026 | Viewed by 228 | Submission Open

Keywords: innate immunity; viral sensing; pattern recognition receptors (PRRs); damage-associated molecular patterns (DAMPs); interferon response; inflammasome activation; viral immune evasion; antiviral defense; trained immunity; immunometabolism

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Neuropathogenesis in HIV Infection: Mechanisms and Reservoirs

edited by Rebecca T. Veenhuis

submission deadline 30 Sep 2026 | Viewed by 223 | Submission Open

Keywords: HIV-associated neuroinflammation; HIV reservoirs; HIV-associated neuropathogenesis; HIV-associated comorbidities

(This special issue belongs to the Section Human Virology and Viral Diseases)

Filoviruses: Ebola and Marburg—Virus–Host Interactions: New Insights into Viral Pathogenesis and Therapeutic Advances

edited by

Asuka Nanbo

submission deadline 30 Sep 2026 | Viewed by 222 | Submission Open

Keywords: virus– host interactions; viral infection mechanisms; viral pathogenesis; therapeutic strategies; vaccine development; advanced experimental technologies

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Re-Emergence of Yellow Fever Virus

edited by Rosemary Sang

submission deadline 30 Sep 2026 | Viewed by 220 | Submission Open

Keywords: yellow fever virus; Orthoflavivirus; mosquito-borne transmission; viral evolution; outbreak expansion; vaccination challenges; molecular epidemiology; control strategies

(This special issue belongs to the Section Human Virology and Viral Diseases)

Common Pathogenic Mechanisms of Plant Viruses

edited by

Yen-Wen Kuo

and Jun Jiang

submission deadline 30 Sep 2026 | Viewed by 218 | Submission Open

Keywords: plant viruses; viral pathogenicity; host– virus interactions; viral replication; virus movement; suppression of RNA silencing; plant immunity; conserved mechanisms; molecular virology

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

Imaging Neurotropic Viruses

edited by

Elena Criscuolo

and

Salla Mattola

submission deadline 30 Sep 2026 | Viewed by 194 | Submission Open

Keywords: neurotropic viruses; neuroinvasion; immune evasion; host– virus interactions; neuronal models; organoids; live-cell microscopy; microfuidics

(This special issue belongs to the Section General Virology)

Plant Viruses and Their Vectors: Epidemiology, Control, and Diagnostics

edited by

Beata Hasiów-Jaroszewska

and

Matthaios M. Mathioudakis

submission deadline 30 Sep 2026 | Viewed by 146 | Submission Open

Keywords: epidemiology; diagnostics tools; virus-vector-host interactions; genetic diversity

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

Zoonotic and Vector-Borne Viral Diseases: 2nd Edition

edited by

Nariman Shahhosseini

submission deadline 1 Oct 2026 | 4 articles | Viewed by 3676 | Submission Open

Keywords: vector-borne viral diseases (VBVDs); vector– host– pathogen interactions; emerging and re-emerging; zoonotic diseases; vectors or reservoirs; vaccine development; and prevention and control measures; One Health

(This special issue belongs to the Section Animal Viruses)

Viruses 2026—New Horizons in Virology

edited by

Eric O. Freed

and

Albert Bosch

submission deadline 1 Oct 2026 | Viewed by 1742 | Submission Open

Keywords: virus; replication; assembly; pathogenesis; outbreak; molecular biology; cell biology; public health; structural biology

(This special issue belongs to the Section General Virology)

Genetic and Epigenetic Regulation of Virus–Host Interaction

edited by

Litao Sun

submission deadline 1 Oct 2026 | Viewed by 257 | Submission Open

Keywords: virus– host interaction; epigenetic regulation; genetic variation; antiviral immunity; post-translational modification; RNA virus; viral infection; host defense response

(This special issue belongs to the Section General Virology)

Epigenetic Modifications in Viral Infections 2026

edited by

Matloob Husain

and

Farjana Ahmed

submission deadline 15 Oct 2026 | Viewed by 185 | Submission Open

Keywords: viral pathogenesis; virus–host interaction; epigenetic modifications; acetylation; methylation; proteomics; genomics

(This special issue belongs to the Section General Virology)

Enteric Viruses in Environment and Humans: Identification, Surveillance and Control

edited by

Rita De Cássia Compagnoli Carmona

and Maria Inês Zanoli Sato

submission deadline 30 Oct 2026 | 7 articles | Viewed by 7249 | Submission Open

Keywords: enteric viruses; wastewater-based epidemiology; human-based epidemiology; One Health

(This special issue belongs to the Section Human Virology and Viral Diseases)

Advances in Animal Influenza Virus Research 2026

edited by

Jansen Araujo

submission deadline 30 Oct 2026 | 2 articles | Viewed by 4562 | Submission Open

Keywords: animal influenza viruses; avian influenza virus; H5N1; viral evolution; viral reassortment; zoonotic potential transmission; diagnostics advances; molecular epidemiology and vaccine development

(This special issue belongs to the Section Animal Viruses)

Advances in Endemic and Emerging Viral Diseases in Livestock: 2nd Edition

edited by

Fernando Vicosa Bauermann

and

Mayara Maggioli

submission deadline 30 Oct 2026 | 1 articles | Viewed by 2341 | Submission Open

Keywords: veterinary virology; livestock; ruminants; swine; vaccines

(This special issue belongs to the Section Animal Viruses)

Tick-Borne Viruses 2026

edited by

Pat Nuttall

submission deadline 31 Oct 2026 | 6 articles | Viewed by 7640 | Submission Open

Keywords: tick-borne viruses; vector-borne pathogens; virus– tick– host interactions; saliva-assisted transmission; tick exosomes; tick antiviral mechanisms; virus evolution; surveillance

(This special issue belongs to the Section General Virology)

Influenza and Other Respiratory Viruses: Prevention, Diagnosis, Treatment: 3rd Edition

edited by

Eric Yager

submission deadline 31 Oct 2026 | 4 articles | Viewed by 4496 | Submission Open

Keywords: influenza; adenovirus; coronoavirus; respiratory syncytial virus; rhinovirus; respiratory virus; antiviral strategies; epidemiology; diagnosis; treatment; vaccination; surveillance; vaccine development

(This special issue belongs to the Section Animal Viruses)

Bacteriophages and Biofilms 2026

edited by

Bartłomiej Grygorcewicz

submission deadline 31 Oct 2026 | 2 articles | Viewed by 3497 | Submission Open

Keywords: bacteriophages; phage therapy; biofilms; phage– biofilm interaction; depolymerases; antibiofilm agents; phage engineering; phage resistance; combination therapy; microbial ecology

(This special issue belongs to the Section Bacterial Viruses)

New Findings in Animal Biosecurity Related to Viral Diseases

edited by

Claude Saegerman

and Jean-Pierre Vaillancourt

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2344 | Submission Open

Keywords: viruses; animal; biosecurity; evaluation; communication; needs; cost– benefit analysis; behaviour change

(This special issue belongs to the Section Animal Viruses)

Recent Advances in Anti-HCV, Anti-HBV and Anti-Flavivirus Agents, 2nd Edition

edited by

Grigoris Zoidis

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1822 | Submission Open

Keywords: medicinal chemistry of anti-HCV; anti-HBV and anti-flavivirus agents; synthesis; structure activity relationships (SAR); antiviral drug discovery; HBV; HCV; Dengue (DENV); Yellow Fever (YFV); West Nile (WNV); Zika (ZIKV); mechanism of action; drug targets; in silico studies

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Early ART Initiation: Impacts on Viral Dynamics and Clinical Outcomes

edited by

Alessandra Vergori

Andrea De Vito

and

Vincenzo Malagnino

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1802 | Submission Open

Keywords: early antiretroviral therapy; HIV viral dynamics; immune recovery; viral reservoir; clinical outcomes; HIV transmission

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Molecular Biomarkers for Viral Infection, 2nd Edition

edited by

Paulina Niedźwiedzka-Rystwej

submission deadline 31 Oct 2026 | 1 articles | Viewed by 994 | Submission Open

Keywords: molecular biomarkers; viral infections; metabolism

(This special issue belongs to the Section General Virology)

Interplay Between Influenza Virus and Host Factors, 2nd Edition

edited by

Matloob Husain

submission deadline 31 Oct 2026 | 1 articles | Viewed by 890 | Submission Open

Keywords: influenza virus; host factors; proviral host factors; antiviral host factors; host adaptation; virus entry; virus assembly; virus release; innate antiviral response; interferon-stimulated genes; post-translational protein modifications

(This special issue belongs to the Section Animal Viruses)

Signaling Pathways in Viral Infection and Antiviral Immunity 2026

edited by

Malathi Krishnamurthy

Praveen Manivannan

, Shelby Clark and Barkha Ramnani

submission deadline 31 Oct 2026 | Viewed by 507 | Submission Open

Keywords: innate immune signaling pathways; antiviral signaling; interferon signaling; cytokine induction and inflammation; host– virus interactions; cell death pathways; autophagy; stress response pathways

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

The Development of Universal Influenza Vaccines

edited by

Yao-Qing Chen

and

Lei Deng

submission deadline 31 Oct 2026 | Viewed by 429 | Submission Open

Keywords: universal influenza vaccine; influenza virus; broadly protective immunity; vaccine development; cross-reactive antibodies

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Arbovirus Diagnosis

edited by Lakshmanane Premkumar and Jesse Waggoner

submission deadline 31 Oct 2026 | Viewed by 412 | Submission Open

Keywords: arboviruses; molecular tests; serology; multiplex assays; diagnostic methods; surveillance; high-throughput assays; point-of-care tests

(This special issue belongs to the Section Human Virology and Viral Diseases)

Plant Protection and Resistance to Viruses

edited by

Patrick Materatski

and

Carla Varanda

submission deadline 31 Oct 2026 | Viewed by 276 | Submission Open

Keywords: plant viruses; plant viral diseases; plant protection; plant– virus interactions; host defense mechanisms; RNA interference; virus-induced gene silencing; plant virus detection and epidemiology; host resistance; sustainable disease management; plant– virus– environment interactions

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

Diagnostics, Antiviral Therapy and Vaccination Against Orthopoxvirus Infections (2nd Edition)

edited by

Sergei N. Shchelkunov

submission deadline 31 Oct 2026 | Viewed by 261 | Submission Open

Keywords: orthopoxvirus; monkeypox; smallpox; vaccinia; antiviral drugs; next-generation vaccines; molecular diagnostics; viral evolution; outbreak

(This special issue belongs to the Section Animal Viruses)

Whiteflies and Whitefly-Transmitted Viruses

edited by Eui-Joon Kil

submission deadline 31 Oct 2026 | Viewed by 230 | Submission Open

Keywords: whitefly; Bemisia tabaci; whitefly-transmitted viruses; begomovirus; crinivirus; torradovirus; virus– vector interaction; virus transmission; molecular diagnosis; high-throughput sequencing

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

2A and 2A-Like Sequences in Viruses: Function, Mechanism and Biotechnological/Biomedical Applications

edited by Martin Ryan and Garry Luke

submission deadline 31 Oct 2026 | Viewed by 224 | Submission Open

Keywords: virus protein biogenesis; ribosome ‘ skipping’ ; protein co-expression; biotechnology; biomedicine

(This special issue belongs to the Section General Virology)

Preparation for the Next Potential Pandemic—Chikungunya, Dengue, Zika and Other Viruses 2026

edited by

Zoltan Vajo

submission deadline 31 Oct 2026 | Viewed by 208 | Submission Open

Keywords: chikungunya; dengue; zika; next pandemic; epidemiology; pharmaceutics; immunology

(This special issue belongs to the Section Human Virology and Viral Diseases)

Viruses and Eye Diseases, 2nd Edition

edited by Homayon Ghiasi and

Deepak Shukla

submission deadline 31 Oct 2026 | Viewed by 194 | Submission Open

Keywords: ocular health; herpesviruses; herpes simplex virus (HSV); varicella zoster virus (VZV); adenovirus; respiratory viruses; Zika virus; cytomegalovirus (CMV); virus– ocular tissue interactions

(This special issue belongs to the Section Human Virology and Viral Diseases)

Molecular Epidemiology, Evolution, and Transmission of Avian Influenza Viruses: 2nd Edition

edited by

Sasan Fereidouni

submission deadline 31 Oct 2026 | 1 articles | Viewed by 191 | Submission Open

Keywords: avian influenza viruses; highly pathogenic avian influenza viruses (HPAIs); molecular epidemiology; phylogeny; evolution; intra- and cross-species transmission

(This special issue belongs to the Section Animal Viruses)

70 Years of Rhinoviruses: From the Common Cold to Complex Pathogens

edited by

Katarzyna Niespodziana

submission deadline 31 Oct 2026 | Viewed by 165 | Submission Open

Keywords: rhinovirus (RV); asthma; COPD; airway; infection; immunity; diversity; therapy; vaccine; history

(This special issue belongs to the Section Human Virology and Viral Diseases)

Plant Virome

edited by

Humberto Debat

submission deadline 31 Oct 2026 | Viewed by 155 | Submission Open

Keywords: plant virology; host– virus interactions; viral ecology; virome evolution; molecular plant pathology

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

Hantaviruses and Their Hosts

edited by Hiroaki Kariwa and

Kumiko Yoshimatsu

submission deadline 31 Oct 2026 | Viewed by 75 | Submission Open

Keywords: hantavirus; hosts; rodents; shrews; bats; moles; virus– host interaction

(This special issue belongs to the Section Animal Viruses)

Neurocognitive Dynamics and Biomarkers in HIV

edited by Mattia Trunfio and Carmela Pinnetti

submission deadline 1 Nov 2026 | 2 articles | Viewed by 3880 | Submission Open

Keywords: HIV infection; neurodegeneration; biomarkers; neuroinflammation; cognitive performance; mood; central nervous system

(This special issue belongs to the Section Human Virology and Viral Diseases)

Maternal-Fetal Interaction in the Antiviral Response

edited by

Maria Notomi Sato

submission deadline 18 Nov 2026 | Viewed by 40 | Submission Open

Keywords: placenta; arboviruses; antiviral response; innate immunity

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Bovine Viral Diarrhea Viruses and Other Pestiviruses

edited by

Enrica Sozzi

submission deadline 30 Nov 2026 | 12 articles | Viewed by 17042 | Submission Open

Keywords: epidemiological survey; prevalence; seroprevalence; bovine viral diarrhoea; mucosal disease; neutralizing antibodies; taxonomy; antiviral drugs; vaccines; species and subgenotypes; wild animal

(This special issue belongs to the Section Animal Viruses)

Human T-Cell Leukemia Virus (HTLV) Infection and Treatment: 2nd Edition

edited by Cynthia A. Pise-Masison and Damian F. J. Purcell

submission deadline 30 Nov 2026 | 5 articles | Viewed by 7277 | Submission Open

Keywords: HTLV; HTLV-associated myelopathy/tropical spastic paraparesis; adult T-cell leukemia/lymphoma; inflammation; neurodegeneration; therapeutics; infectious dermatitis; cancer; antiviral drugs

(This special issue belongs to the Section Human Virology and Viral Diseases)

Cellular Immune Response to Hepatitis Viruses

edited by

Armando Andres Roca Suarez

submission deadline 30 Nov 2026 | 2 articles | Viewed by 5618 | Submission Open

Keywords: viral hepatitis; viral/host interactions; immune response; immune evasion; immunopathogenesis; immunomodulatory therapy; pre-clinical models

(This special issue belongs to the Section Human Virology and Viral Diseases)

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