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Viruses publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Canine Distemper Virus

edited by Monica G. Candela and

Nieves Ortega Hernández

submission deadline 30 Jun 2025 | 9 articles | Viewed by 13529 | Submission Open

Keywords: CDV taxonomy (lineages); new hosts of CDV; CDV pathogenesis; CDV epidemiology (risk factors; distribution; and prevalence); CDV prevention/risk mitigation

(This special issue belongs to the Section Animal Viruses)

Controlling Zoonotic Viral Diseases from One Health Perspective 2025

edited by

Maureen T. Long

and Erika Schwarz-Collins

submission deadline 30 Jun 2025 | 5 articles | Viewed by 11194 | Submission Open

Keywords: one health; viral zoonoses; control; vaccine; surveillance; epidemiology

(This special issue belongs to the Section Animal Viruses)

Viral Sepsis: Pathogenesis, Diagnostics and Therapeutics

edited by

Karolina Akinosoglou

and

Charalambos Gogos

submission deadline 30 Jun 2025 | 6 articles | Viewed by 10661 | Submission Open

Keywords: viral sepsis; HIV; HBV; HCV; EBV; HDV; HEV; CMV; HSV; HPV; influenza; RSV; COVID-19; SARS-CoV-2; other viruses; viral infection; sepsis; pathogenesis; diagnosis; therapy; biomarkers; vaccination

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Advances in Alphavirus and Flavivirus Research, 2nd Edition

edited by

Young Chan Kim

and

Arturo Reyes-Sandoval

submission deadline 30 Jun 2025 | 9 articles | Viewed by 10243 | Submission Open

Keywords: arbovirus; alphavirus; flavivirus; Chikungunya; Mayaro; Zika; dengue; diagnostics; surveillance; vaccine; antivirals; animal models

(This special issue belongs to the Section General Virology)

Vertical Transmission of Human Papillomavirus Infections

edited by

Stina Syrjänen

submission deadline 30 Jun 2025 | 3 articles | Viewed by 10107 | Submission Open

(This special issue belongs to the Section Animal Viruses)

Cellular Restriction Factors against Viral Infection

edited by

Stephen Barr

submission deadline 30 Jun 2025 | 2 articles | Viewed by 9612 | Submission Open

Keywords: cellular restriction factors; antiviral proteins; viral antagonists; intrinsic immunity; interferon response; innate immunity; evolution of restriction factors; evolution of viral antagonists; viral antagonists as druggable targets

(This special issue belongs to the Section General Virology)

Immune Modulation by Human Cytomegalovirus

edited by

Davide Abate

submission deadline 30 Jun 2025 | 6 articles | Viewed by 9411 | Submission Open

Keywords: human cytomegalovirus (CMV); molecular and cellular mechanisms; cell-intrinsic immunity; adaptive immunity; innate immunity

(This special issue belongs to the Section Human Virology and Viral Diseases)

Viral Hepatitis and Liver Diseases

edited by

Carlo Smirne

submission deadline 30 Jun 2025 | 7 articles | Viewed by 8858 | Submission Open

Keywords: chronic viral infection; viral hepatitis; liver fibrosis; hepatocellular carcinoma; hepatitis B virus; hepatitis C virus; hepatitis delta virus co-infection; hepatitis E virus; flavivirus; molecular mechanisms; epidemiological investigations

(This special issue belongs to the Section Human Virology and Viral Diseases)

Coronaviruses and Influenza Viruses: Evolution, Cross-Species Transmission, and Recombination

edited by

Maged Gomaa Hemida

submission deadline 30 Jun 2025 | 4 articles | Viewed by 5425 | Submission Open

Keywords: coronaviruses; influenza viruses; highly pathogenic influenza viruses; species jump; avian coronaviruses; porcine coronaviruses; vaccines; diagnostic assays; one health; virus/host interaction.

(This special issue belongs to the Section Coronaviruses)

Diversity and Coinfections of Plant or Fungal Viruses, 3rd Edition

edited by

Islam Hamim

Ken Komatsu

and

Hiromitsu Moriyama

submission deadline 30 Jun 2025 | 3 articles | Viewed by 5053 | Submission Open

Keywords: diagnosis; surveillance; molecular mechanism; viroid; subviral agents; mycoviruses; biological control; pesticide resistance; antiviral defense mechanism; population genetics; recombination; gene expressions; host range

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

Plant Virus Spillovers

edited by

Steve Wylie

and

Nuredin Habili

submission deadline 30 Jun 2025 | 3 articles | Viewed by 4931 | Submission Open

Keywords: spillover; emergence; replication; wild-plant virus; transmission; virus-cell interaction; vector

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

Viruses and Eye Diseases

edited by Homayon Ghiasi and

Deepak Shukla

submission deadline 30 Jun 2025 | 3 articles | Viewed by 4334 | Submission Open

Keywords: ocular health; herpesviruses; herpes simplex virus (HSV); varicella zoster virus (VZV); adenovirus; respiratory viruses; Zika virus; cytomegalovirus (CMV); virus– ocular tissue interactions

(This special issue belongs to the Section Human Virology and Viral Diseases)

Zoonotic Viral Diseases: Drivers, Causes, Prevention and Cure, 2nd Edition

edited by

Claude Saegerman

submission deadline 30 Jun 2025 | 4 articles | Viewed by 3580 | Submission Open

Keywords: zoonotic viral diseases; drivers of emergence; disease mechanism and pathogenesis in reservoir host and end host; prevention mitigation measures; treatment

(This special issue belongs to the Section Animal Viruses)

Interplay Between Influenza Virus and Host Factors

edited by

Matloob Husain

submission deadline 30 Jun 2025 | 2 articles | Viewed by 3474 | Submission Open

Keywords: influenza virus; host factors; proviral host factors; antiviral host factors; host adaptation; virus entry; virus assembly; virus release; innate antiviral response; interferon-stimulated genes; post-translational protein modifications

(This special issue belongs to the Section Animal Viruses)

HIV Protease

edited by

Gail E. Fanucci

submission deadline 30 Jun 2025 | 2 articles | Viewed by 3027 | Submission Open

Keywords: HIV protease; antiretroviral therapy; drug resistance; inhibitor development; viral maturation; viral co-evolution; natural polymorphism

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Interferon Signaling in Viral Pathogenesis

edited by Lishan Su

submission deadline 30 Jun 2025 | 1 articles | Viewed by 886 | Submission Open

Keywords: type I interferons; virus replication; viral pathogenesis; autoimmune diseases; inflamation-induced cancer; immunotherapy

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Bacteriophage Diversity, 2nd Edition

edited by Bert Ely

submission deadline 30 Jun 2025 | 1 articles | Viewed by 664 | Submission Open

Keywords: bacteriophages phage; diversity genome; evolution; new genera; phage-host interactions

(This special issue belongs to the Section Bacterial Viruses)

Viral Manipulation of Plant Stress Responses

edited by

Miguel A. Aranda

and Manuel Miras

submission deadline 30 Jun 2025 | Viewed by 502 | Submission Open

Keywords: virus– plant interactions; virus– host– vector interactions; immune responses; hormone signaling; evolutionary adaptations; crop protection; stress responses

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

Epigenetic Modifications in Viral Infections, Volume II

edited by

Matloob Husain

and

Farjana Ahmed

submission deadline 1 Jul 2025 | 1 articles | Viewed by 589 | Submission Open

Keywords: viral pathogenesis; virus– host interaction; epigenetic modifications; acetylation; methylation; proteomics; genomics

(This special issue belongs to the Section General Virology)

Glycans in Virus-Host Interactions

edited by Rahul Raman

submission deadline 15 Jul 2025 | 4 articles | Viewed by 14490 | Submission Open

Keywords: glycoeptiope; glycan receptors; viruses; antibodies; lectins

(This special issue belongs to the Section Animal Viruses)

Unraveling the Pathogenesis of Persistent Virus Infection

edited by

Yasuko Tsunetsugu-Yokota

and Mie Kobayashi-Ishihara

submission deadline 15 Jul 2025 | 6 articles | Viewed by 12422 | Submission Open

Keywords: pathophysiology; persistent virus infections; chronic diseases; latency; reactivation

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Flow Virometry: A New Tool for Studying Viruses

edited by John Yin

submission deadline 15 Jul 2025 | 5 articles | Viewed by 8958 | Submission Open

Keywords: flow virometry; virus particle detection; virus counting; virus labeling/staining; virus-like particles; scanning ion occlusion sensing

(This special issue belongs to the Section General Virology)

Arboviral Diseases in Livestock

edited by

Estelle Venter

and

Antoinette Van Schalkwyk

submission deadline 15 Jul 2025 | 2 articles | Viewed by 2124 | Submission Open

Keywords: arbovirus; epidemiology; diagnostics; vaccines

(This special issue belongs to the Section Animal Viruses)

Advances in Small-Molecule Viral Inhibitors

edited by Chiara Bertagnin

submission deadline 15 Jul 2025 | 2 articles | Viewed by 424 | Submission Open

Keywords: small-molecule inhibitors; PROTACs; antiviral compounds; drug discovery; protein– protein interaction inhibitors; enzymatic inhibitors

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Spumaretroviruses: Research and Applications

edited by

Arifa S. Khan

, Marcelo A. Soares,

Dirk Lindemann

and Martin Löchelt

submission deadline 30 Jul 2025 | Viewed by 635 | Submission Open

Keywords: ancient retroviruses; antivirals; complex retroviruses; endogenous elements; foamy viruses; foamy virus-host interactions; foamy virus prevalence; foamy virus vectors; immune responses; molecular biology and replication; natural infections; nonhuman primates and non-primates; restriction factors spumaretroviruses; structural biology; taxonomy; viral proteins; virus detection assays; zoonoses

(This special issue belongs to the Section Animal Viruses)

COVID-19 Complications and Co-infections

edited by Amir Sohail,

Abu Baker Sheikh

and

Adeel Nasrullah

submission deadline 31 Jul 2025 | 17 articles | Viewed by 27795 | Submission Open

Keywords: SARS-CoV-2; COVID-19; complications; co-infections; hospitalization

(This special issue belongs to the Section Coronaviruses)

Bovine Influenza

edited by Dan Wang and

Feng Li

submission deadline 31 Jul 2025 | 5 articles | Viewed by 16432 | Submission Open

Keywords: cattle; influenza viruses; avian influenza; replication; virulence; transmission; host adaptation; reservoir; epidemiology; one health; vaccine; immune response

(This special issue belongs to the Section Animal Viruses)

Herpesviruses and Associated Diseases

edited by

Sherif T.S. Hassan

submission deadline 31 Jul 2025 | 11 articles | Viewed by 13680 | Submission Open

Keywords: human herpesviruses; animal herpesviruses; viral latency and reactivation; immune evasion strategies; herpesvirus– host interactions; herpesvirus biology and pathogenesis; herpesvirus diagnosis; environmental factors; herpesvirus-associated diseases; prevention and treatment strategies; antiviral therapies; vaccine development

(This special issue belongs to the Section Human Virology and Viral Diseases)

Saliva in the Diagnosis of Viral Diseases

edited by

Anna Rosa Garbuglia

and

Licia Bordi

submission deadline 31 Jul 2025 | 6 articles | Viewed by 11945 | Submission Open

Keywords: saliva; diagnosis; pathogen detection; immunity; biomarkers

(This special issue belongs to the Section Human Virology and Viral Diseases)

The Application of Viruses to Biotechnology 3.0

edited by

Carla Varanda

and

Patrick Materatski

submission deadline 31 Jul 2025 | 5 articles | Viewed by 11217 | Submission Open

Keywords: viral vectors; plant protection; gene therapy; virus-based vaccines; viral nanotechnology; phage display; viral gene delivery; virus-mediated gene editing; virus-like particles (VLPs)

(This special issue belongs to the Section General Virology)

Evolution and Adaptation of Avian Viruses

edited by

Giovanni Franzo

and

Matteo Legnardi

submission deadline 31 Jul 2025 | 5 articles | Viewed by 8612 | Submission Open

Keywords: virus; poultry; evolution; genetics; diagnosis; host; epidemiology; control; vaccine

(This special issue belongs to the Section Animal Viruses)

Virus Assembly and Genome Packaging

edited by

Mauricio Comas-Garcia

submission deadline 31 Jul 2025 | 2 articles | Viewed by 4357 | Submission Open

Keywords: viral assembly; genome packaging; viral structural proteins; host protein; viral– host interactions; antiviral therapies

(This special issue belongs to the Section General Virology)

Novel Strategies to Identify and Eliminate Latent HIV Cells

edited by

Francesco Andrea Procopio

submission deadline 31 Jul 2025 | 1 articles | Viewed by 3211 | Submission Open

Keywords: HIV; HIV-1 infection; antiretroviral therapy (ART); HIV single cell analysis; HIV reservoir; HIV cure

(This special issue belongs to the Section Human Virology and Viral Diseases)

Virus-Host Protein Interactions

edited by

Benoit Coulombe

submission deadline 31 Jul 2025 | 3 articles | Viewed by 3083 | Submission Open

Keywords: protein– protein interactions; antiviral drug discovery; protein target inhibitors

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

Viral Resistance

edited by

Maria Antonia De Francesco

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2623 | Submission Open

Keywords: antiviral drugs; resistance; mechanism; mutations; viral escape; viral adaptation; variability; combination therapy

(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)

HIV Assembly, Release and Maturation

edited by Siddhartha Datta

submission deadline 31 Jul 2025 | 1 articles | Viewed by 2207 | Submission Open

Keywords: HIV assembly and maturation; capsid stability; inositol hexakisphosphate (IP6); genome recognition; endogenous reverse transcription; reorganization; maturation inhibitors; flexibility and dynamics

(This special issue belongs to the Section Human Virology and Viral Diseases)

SARS-CoV-2 Neutralizing Antibodies 3rd Edition

edited by Youchun Wang

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2173 | Submission Open

Keywords: SARS-CoV-2; neutralizing antibodies; neutralization assays; standards; monoclonal antibodies; vaccines; viral variants

(This special issue belongs to the Section Coronaviruses)

An Update on Enterovirus Research, 2nd Edition

edited by

Benjamin M. Liu

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1576 | Submission Open

Keywords: antivirals; enteroviruses; picornavirus; diagnostics; emerging and re-emerging diseases; viral proteins; virus replication; viral targets; virus– host interactions; vaccine development

(This special issue belongs to the Section Human Virology and Viral Diseases)

Cascade of Care for HIV, Hepatitis and Sexually Transmitted Infections

edited by

Justyna Dominika Kowalska

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1006 | Submission Open

Keywords: HIV; AIDS; cascade; linkage; HCV; HBV; sexually transmitted infections

(This special issue belongs to the Section Human Virology and Viral Diseases)

Biosecurity and Plant Viruses: A Call to Action for a Sustainable Future

edited by

Yi Xu

and

Patricia Valle Pinheiro

submission deadline 31 Jul 2025 | 1 articles | Viewed by 926 | Submission Open

Keywords: biosecurity; viral disease; sustainable agriculture; emerging plant viruses; quarantine regulations

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

Multiple Hosts of SARS-CoV-2, 3rd Edition

edited by

Suresh Varma Kuchipudi

and Santhamani Ramasamy

submission deadline 31 Jul 2025 | 1 articles | Viewed by 675 | Submission Open

Keywords: SARS-CoV-2; animal– human interface; animal reservoirs; One Health; pathogenicity and pathogenesis; spillover and spillback; surveillance; virus evolution and adaptation; zoonoses and reverse zoonoses

(This special issue belongs to the Section Coronaviruses)

Viral Diseases of Major Crops

edited by Zaifeng Fan and Yan Shi

submission deadline 31 Jul 2025 | Viewed by 441 | Submission Open

Keywords: viral infection; viral pathogenicity; virus movement; replication; RNA silencing suppressor; host response; host factors; molecular plant– virus– vector interactions

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

Maternal to Child Transmission of HIV and the Effects on Pregnancy

edited by Marta López,

Azucena Bardají

and

Raquel González

submission deadline 31 Jul 2025 | Viewed by 433 | Submission Open

Keywords: maternal to child transmission; perinatal transmission; pregnancy outcomes; HIV in pregnancy; antiretroviral treatment; preventive strategies; adverse perinatal outcome; prematurity and low birthweight

(This special issue belongs to the Section Human Virology and Viral Diseases)

Synanthropy and Zoonotic Viral Spillover

edited by

João R. Mesquita

submission deadline 31 Jul 2025 | Viewed by 398 | Submission Open

Keywords: zoonoses; synanthropic interactions; virus; emergence; spillover

(This special issue belongs to the Section Animal Viruses)

Human Adenovirus (HAdV) Infection in Children

edited by Adriana Kajon and

Glen R. Nemerow

submission deadline 31 Jul 2025 | Viewed by 348 | Submission Open

Keywords: epidemiology; pediatric; transplant recipients; antivirals; outbreak; acute respiratory illness; gastroenteritis

(This special issue belongs to the Section Human Virology and Viral Diseases)

Mass Spectrometry and Viral Analysis

edited by Paul D. Gershon

submission deadline 31 Jul 2025 | Viewed by 232 | Submission Open

Keywords: mass spectrometry; viral analysis; mass analysis; virus interaction; dynamics; viral proteins

(This special issue belongs to the Section General Virology)

Simian Immunodeficiency Virus Models of HIV/AIDS in Nonhuman Primates, 2nd Edition

edited by Nina Derby,

Jennifer A. Manuzak

and

Donald Sodora

submission deadline 31 Jul 2025 | Viewed by 227 | Submission Open

Keywords: human immunodeficiency virus (HIV); simian immunodeficiency virus (SIV); HIV latency; pathogenesis; cure; vaccination; co-infection; transmission; non-human primate models

(This special issue belongs to the Section Animal Viruses)

Understanding and Control of Rice Viruses

edited by

Shuai Fu

Tong Zhang

and

Yi Xu

submission deadline 31 Jul 2025 | Viewed by 167 | Submission Open

Keywords: rice viruses; virus detection techniques; virus– host interactions; rice plant resistance to viruses; emerging rice viruses; viral epidemiology; viral diseases management; insect vectors; AI-driven rice virus detection and control

(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)

Role of Bacteriophage in Intestine Microbial Communities

edited by Yi Duan

submission deadline 31 Jul 2025 | Viewed by 127 | Submission Open

Keywords: bacteriophage; intestinal microbiome; virome; microbial homeostasis; phage therapy; gut ecology; intestinal dysbiosis; antimicrobial resistance; microbiome engineering; host– microbe interactions

(This special issue belongs to the Section Bacterial Viruses)

Zoonotic and Vector-Borne Viral Diseases

edited by

Nariman Shahhosseini

and Gary Kobinger

submission deadline 1 Aug 2025 | 12 articles | Viewed by 18930 | Submission Open

Keywords: vector-borne viral diseases (VBVDs); vector– host– pathogen interactions; emerging and re-emerging zoonotic diseases; vectors or reservoirs; vaccine development; and prevention and control measures

(This special issue belongs to the Section Animal Viruses)

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