Viral Neuropathogenesis: Mechanisms, Models, and Therapeutic Strategies

Dear Colleagues,

Viral infections of the central nervous system (CNS) remain a major global health concern due to their high morbidity, mortality, and long-term neurological sequelae. A wide range of neurotropic viruses, including RNA and DNA viruses, can invade and damage neural tissues, resulting in encephalitis, meningitis, or neurodegenerative outcomes. Despite significant advances in virology and immunology, the mechanisms underlying CNS viral entry, spread, immune evasion, and neuropathology remain incompletely understood.

This Special Issue, “Viral Neuropathogenesis: Mechanisms, Models, and Therapeutic Strategies,” aims to highlight the latest progress in understanding how viruses interact with the nervous system, alter neuronal and glial cell function, and modulate host immune responses. We invite submissions exploring molecular and cellular mechanisms of neuroinvasion, host–pathogen interactions, immune-mediated pathology, and the development of preventive or therapeutic strategies.

Contributions may include studies utilizing in vitro, in vivo, or computational models, as well as translational or clinical research addressing acute and chronic neurological complications following viral infection. Both original research articles and comprehensive reviews are welcome.

Dr. Mukesh Kumar
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the Special Issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.