Special Issues

Viruses publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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HIV and HTLV Infections and Coinfections (2nd Edition) submission deadline 1 Jan 2027 | 1 articles | Viewed by 1230 | Submission Open
Keywords: HTLV; HIV; infection; co-infection
(This special issue belongs to the Section Human Virology and Viral Diseases)
Avian Viruses and Antiviral Immunity
edited by and
submission deadline 15 Jan 2027 | 11 articles | Viewed by 11141 | Submission Open
Keywords: avian viruses; antiviral immunity; pathogenic mechanism; vaccine development; antiviral drugs; epidemiological dynamics; prevention and control; viral diseases of poultry and wild birds 
(This special issue belongs to the Section Animal Viruses)
Vaccines and Therapeutics Against Orthoflaviviruses
edited by and Liang Qiao
submission deadline 28 Jan 2027 | Viewed by 300 | Submission Open
Keywords: orthoflaviruses; vaccines; immunity; therapeutic agents; neutralizing antibodies; animal models; pathogenesis; protective efficacy
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Influenza Viruses in Wildlife 2026 submission deadline 31 Jan 2027 | 6 articles | Viewed by 8107 | Submission Open
Keywords: avian influenza; wild birds; wildlife; influenza epidemiology; surveillance; HPAI
(This special issue belongs to the Section Animal Viruses)
Chikungunya Virus in Viral Immunology and Vaccine Research
edited by Shuaiyao Lu and
submission deadline 31 Jan 2027 | 2 articles | Viewed by 3177 | Submission Open
Keywords: Chikungunya virus; viral immunology; CHIKV vaccine development; virus–host interactions; innate immunity; adaptive immunity; neutralizing antibodies; viral pathogenesis; vaccine platforms; antivirals; Alpha virus
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Hepatitis Virus Genetic Heterogeneity: Impact in Epidemiology and Clinical Pathology
edited by , and Diego Flichman
submission deadline 31 Jan 2027 | 2 articles | Viewed by 2780 | Submission Open
Keywords: viral hepatitis; molecular diagnostics; genotyping; molecular epidemiology; antiviral therapy; drug resistance; genomic surveillance
(This special issue belongs to the Section Human Virology and Viral Diseases)
Canine Distemper Virus: 2nd Edition
edited by Monica G. Candela and
submission deadline 31 Jan 2027 | 3 articles | Viewed by 2607 | Submission Open
Keywords: CDV taxonomy (lineages); new hosts of CDV; CDV pathogenesis; CDV epidemiology (risk factors, distribution, and prevalence); CDV prevention/risk mitigation
(This special issue belongs to the Section Animal Viruses)
High Consequence Viral Transmission
edited by
submission deadline 31 Jan 2027 | 2 articles | Viewed by 2276 | Submission Open
Keywords: high-consequence viruses; zoonotic viruses; spillover events; natural reservoirs; wildlife vectors; pandemic; outbreaks; airborne transmission; droplet transmission; sexual transmission; high fatality rates; Filoviridae; Orthoebolavirus; Orthomarbugvirus; Paramyxoviridae; Orthoparamyxovirinae; Arenaviridae; Mammarenavirus; Peribunyaviridae; Orthobunyavirus; Nairoviridae; Orthonairovirus; Hantaviridae; Orthohantavirus; Coronaviridae; Betacoronavirus
(This special issue belongs to the Section Human Virology and Viral Diseases)
Filoviruses: Pathogenesis, Immunity, and Countermeasures
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 822 | Submission Open
Keywords: filoviruses; ebola virus (EBOV); marburg virus (MARV); taï forest virus (TAFV); sudan virus (SUDV); reston virus (RESTV); bombali virus (BOMV); bundibugyo virus (BDBV); cytokine storm; viral pathogenesis; immunity; countermeasures; type-I interferons; inflammatory cytokines
(This special issue belongs to the Section Animal Viruses)
Viral Non-Structural Proteins
edited by
submission deadline 31 Jan 2027 | Viewed by 801 | Submission Open
Keywords: viral genome; non-structural proteins; virus replication; vaccines; viral therapeutics
(This special issue belongs to the Section General Virology)
Adenovirus Cell and Immune Interactions 2026
edited by
submission deadline 31 Jan 2027 | Viewed by 410 | Submission Open
Keywords: adenovirus; gene therapy; vaccine; immune system; respiratory disease; structure
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Antiviral Protease Inhibitors
edited by Xufang Deng and
submission deadline 31 Jan 2027 | 1 articles | Viewed by 363 | Submission Open
Keywords: antiviral drug discovery; high-throughput screen; structure-guided drug design; artificial intelligence (AI)-based drug discovery; drug resistance; combination therapies; antiviral assay development; host-targeting antiviral
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Advances in the Dynamics of Viral Structures
edited by and Celia A. Schiffer
submission deadline 31 Jan 2027 | Viewed by 309 | Submission Open
Keywords: virus structure; conformational dynamics; molecular interactions; viral proteins; antiviral drug design; protein structure; functional dynamics; molecular simulations; biophysical spectroscopy; crystallography; cryo-EM; NMR
(This special issue belongs to the Section General Virology)
Flow Virometry: A New Tool for Studying Viruses: 2nd Edition
edited by John Yin
submission deadline 31 Jan 2027 | Viewed by 291 | Submission Open
Keywords: flow virometry; virus particle detection; virus counting; virus labeling/staining; virus-like particles; scanning ion occlusion sensing
(This special issue belongs to the Section General Virology)
Viral Neuropathogenesis: Mechanisms, Models, and Therapeutic Strategies
edited by
submission deadline 31 Jan 2027 | Viewed by 289 | Submission Open
Keywords: neurotropic viruses; neuroinflammation; blood–brain barrier; CNS viral infection models; host–pathogen interactions; antiviral immunity; neurological complications; neurodegeneration; viral encephalitis
Physical Virology—Viral Ways for Navigating the Space Mesoscale
edited by Bogdan G. Dragnea
submission deadline 31 Jan 2027 | Viewed by 263 | Submission Open
Keywords: virus mechanics; virus acoustic modes; virus assembly thermodynamics; virus assembly kinetics; protein shell symmetry; virus-like particle applications; virus–interface interactions
(This special issue belongs to the Section General Virology)
Impact of Evolution on Herpesvirus Pathogenesis
edited by
submission deadline 31 Jan 2027 | Viewed by 213 | Submission Open
Keywords: herpesviruses; evolution; pathogenesis
(This special issue belongs to the Section Human Virology and Viral Diseases)
Viral Immune Evasion and Host Defense: Mechanisms and Therapeutic Targets submission deadline 31 Jan 2027 | Viewed by 205 | Submission Open
Keywords: viral immune evasion; host antiviral defense; emerging and re-emerging viruses; innate immune signaling; targeted antiviral therapies
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Flaviviridae: Advances in Diagnosis, Prevention, and Control Strategies
edited by
submission deadline 31 Jan 2027 | Viewed by 170 | Submission Open
Keywords: flaviviridae; dengue virus; Zika virus; virus–host interactions; antiviral strategies; host-directed therapy; viral pathogenesis; emerging viruses
(This special issue belongs to the Section Animal Viruses)
Phage Ecology and Evolution in Animal Health
edited by
submission deadline 31 Jan 2027 | Viewed by 164 | Submission Open
Keywords: antimicrobial resistance; host–microbe interactions; phage ecology; phage evolution; veterinary microbiology
(This special issue belongs to the Section Bacterial Viruses)
Animal Herpesvirus: 3rd Edition
edited by
submission deadline 31 Jan 2027 | Viewed by 129 | Submission Open
Keywords: herpesviruses; innate immune responses; host adaptive immune responses; herpesvirus-host; interactions; susceptibility
(This special issue belongs to the Section Animal Viruses)
Advances in HIV Treatment, Prevention, and Cure Interventions
edited by Ricardo Sobhie Diaz and Mauro Schechter
submission deadline 31 Jan 2027 | 1 articles | Viewed by 105 | Submission Open
Keywords: pre-exposure prophylaxis; novel antiretroviral treatment targets; HIV residual replication; decreasing HIV reservoir; HIV micoinflamtion
(This special issue belongs to the Section Human Virology and Viral Diseases)
An Update on Enterovirus Research, 3rd Edition
edited by
submission deadline 31 Jan 2027 | Viewed by 102 | Submission Open
Keywords: antivirals; enteroviruses; picornavirus; diagnostics; emerging and re-emerging diseases; viral proteins; virus replication; viral targets; virus–host interactions; vaccine development
(This special issue belongs to the Section Human Virology and Viral Diseases)
Pediatric Viral Gastroenteritis
edited by Filemon Bucardo and Sylvia Becker-Dreps
submission deadline 31 Jan 2027 | Viewed by 97 | Submission Open
Keywords: gastrointestinal track; rotavirus; norovirus; sapovirus; astrovirus
(This special issue belongs to the Section Human Virology and Viral Diseases)
Gammaherpesvirus Infection and Host Immune Response
edited by and
submission deadline 31 Jan 2027 | Viewed by 96 | Submission Open
Keywords: gammaherpesvirus; infection mechanisms; host immune response; oncogenic mechanisms; therapeutic strategies
(This special issue belongs to the Section General Virology)
Genomic Surveillance of Emerging and Re-Emerging Viruses
edited by
submission deadline 31 Jan 2027 | Viewed by 44 | Submission Open
Keywords: emerging viruses; viral evolution; next-generation sequencing; genomic epidemiology; metagenomics; livestock; wildlife; environment; one health
(This special issue belongs to the Section General Virology)
Molecular Mechanisms and Clinical Manifestations of Persistent Viral Infections (2nd Edition)
edited by and Simone La Frazia
submission deadline 1 Feb 2027 | Viewed by 288 | Submission Open
Keywords: mammalian viruses; chronic infection; latent infection; HIV; HPV; HBV; HCV; HSV; pathogenetic mechanisms; molecular pathways; oncogenic processes; immunity; antiviral drugs; endogenous viral element
(This special issue belongs to the Section Human Virology and Viral Diseases)
Insect-Specific Viruses and Biological Control of Arboviruses submission deadline 6 Feb 2027 | 1 articles | Viewed by 2308 | Submission Open
Keywords: insect-specific virus; mosquito-specific virus; arbovirus; evolution; vaccine; biological control; interference
(This special issue belongs to the Section Invertebrate Viruses)
Viral Entry and Membrane Fusion
edited by Fabiana Carneiro
submission deadline 16 Feb 2027 | 1 articles | Viewed by 995 | Submission Open
Keywords: viral entry; membrane fusion; virus–host interactions; endocytosis; antiviral strategies
(This special issue belongs to the Section General Virology)
Viral Infections in Hematopoietic Stem Cell Transplant and Cellular Therapy Recipients, 2nd Edition
edited by Sanjeet Singh Dadwal
submission deadline 26 Feb 2027 | Viewed by 405 | Submission Open
Keywords: HSCT; GVHD; HHV6; CMV; adenovirus; BK and JC virus (polyomaviruses); HIV
(This special issue belongs to the Section Human Virology and Viral Diseases)
Oncogenic Infections and Cancer: Clinical Insights and Emerging Therapeutics
edited by G. Hossein Ashrafi and Mustafa Ozdogan
submission deadline 28 Feb 2027 | 5 articles | Viewed by 8296 | Submission Open
Keywords: oncogenesis; viral oncology; bacterial oncogenesis; human papillomavirus (HPV); Epstein–Barr virus (EBV); Kaposi’s sarcoma-associated herpesvirus (KSHV); hepatitis B virus (HBV); hepatitis C virus (HCV); human T-lymphotropic virus (HTLV-1); Helicobacter pylori; infection-driven cancers; molecular mechanisms; tumor microenvironment; immunotherapy; viral persistence; antiviral therapies; CRISPR-based treatments; cancer prevention; vaccine development; immune checkpoint inhibitors; diagnostic biomarkers; personalized medicine; translational oncology; therapeutic resistance; emerging therapeutics
(This special issue belongs to the Section Human Virology and Viral Diseases)
Plant Viral Pathogens: Innovations in Detection, Genetic Diversity, and Evolutionary Dynamics
edited by
submission deadline 28 Feb 2027 | 5 articles | Viewed by 7392 | Submission Open
Keywords: high-throughput sequencing; RT-PCR and qRT-PCR; genetic diversity; virus evolution; mutations; reassortment; recombination
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
HIV and Drugs of Abuse, 4th Edition submission deadline 28 Feb 2027 | 3 articles | Viewed by 5433 | Submission Open
Keywords: substance use disorders; HIV; HAND; methamphetamine
(This special issue belongs to the Section Human Virology and Viral Diseases)
Interferon-Stimulated Genes in Antiviral Immunity
edited by
submission deadline 28 Feb 2027 | 3 articles | Viewed by 4441 | Submission Open
Keywords: interferon-stimulated genes; ISGs; non-coding RNA; viral replication; deep learning tools
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Emerging and Reemerging Plant Viruses in a Changing World: 2nd Edition
edited by
submission deadline 28 Feb 2027 | 4 articles | Viewed by 3530 | Submission Open
Keywords: emerging and re-emerging viruses; virus spillover; climate change and global trade; mixed infections; plant–virus–vector relationships
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Innovative Prophylactic and Therapeutics for the Treatment of Coronavirus Infection
edited by and Jun-Gyu Park
submission deadline 28 Feb 2027 | 2 articles | Viewed by 3070 | Submission Open
Keywords: prophylactic; therapeutics; SARS-CoV-2; viral variants; antivirals
(This special issue belongs to the Section Coronaviruses)
Cellular Mechanisms Regulating HIV Replication, 2nd Edition
edited by
submission deadline 28 Feb 2027 | 1 articles | Viewed by 2109 | Submission Open
Keywords: HIV-1; HIV-1 replication; host factors
(This special issue belongs to the Section Human Virology and Viral Diseases)
Circoviruses in Domestic and Wild Animals
edited by , Yingli Shang and
submission deadline 28 Feb 2027 | 1 articles | Viewed by 1311 | Submission Open
Keywords: circoviruses; porcine circovirus; diagnosis; epidemiology; vaccines; pathogenesis; host immunity; wildlife virology
(This special issue belongs to the Section Animal Viruses)
Application of Genetically Engineered Plant Viruses, 2nd Edition
edited by and Chu-Hui Chiang
submission deadline 28 Feb 2027 | 1 articles | Viewed by 1208 | Submission Open
Keywords: plant virus; infectious clone; viral vector; virus-induced gene silencing (VIGS); virus-like particles (VLPs); cross-protection
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Porcine Virus–Host Interactions: Entry, Tropism, Immune Evasion and Control
edited by
submission deadline 28 Feb 2027 | Viewed by 469 | Submission Open
Keywords: porcine viruses; virus–host interactions; viral entry; tropism; immune evasion; viral escape; antivirals; single-cell/spatial omics; cell imaging; virus trafficking
(This special issue belongs to the Section Animal Viruses)
Acute and Persistent Immune Responses to Respiratory Infections and Vaccines—Mucosal and Systemic
edited by Julian Tang
submission deadline 28 Feb 2027 | Viewed by 407 | Submission Open
Keywords: respiratory viruses; coronaviruses; SARS-CoV-2; influenza; parainfluenza; RSV (respiratory syncytial virus); adenoviruses; rhinoviruses; enteroviruses; host immune responses; mucosal immunity; systemic immunity; clinical disease severity; virus transmission; infection control; vaccine responses
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Immune Mechanisms Against Respiratory Viral Pathogens
edited by Telugu Akula Narasaraju and Sunil More
submission deadline 28 Feb 2027 | Viewed by 381 | Submission Open
Keywords: respiratory viral infections; innate and adaptive immunity; host–pathogen interactions; inflammatory response; therapeutic interventions
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Bats as Viral Reservoirs: From Discovery to Pandemic Preparedness submission deadline 28 Feb 2027 | Viewed by 117 | Submission Open
Keywords: virus; bat; reservoir; infection
(This special issue belongs to the Section Animal Viruses)
Immune Responses and Antiviral Strategies Against Emerging RNA Viruses
edited by
submission deadline 28 Feb 2027 | Viewed by 99 | Submission Open
Keywords: host–virus interactions; viral recombination; immune evasion; systems virology
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Novel Antiviral Strategies: Direct-Acting and Host-Directed Antivirals
edited by and
submission deadline 28 Feb 2027 | Viewed by 95 | Submission Open
Keywords: direct-acting antivirals (DAA); host-directed antivirals (HDA); antiviral resistance evolution; host–pathogen interactome; broad-spectrum efficacy; structure-based drug design; targeted protein degradation; one health therapeutics
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Targeted Inhibition of Viral Proteins
edited by Kaiming Tang
submission deadline 28 Feb 2027 | Viewed by 57 | Submission Open
Keywords: emerging infetious diseases; emerging and re-emerging viruses; viral protein; targeted inhibition; antiviral drug; drug resistence; artificial intelligence
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Viral Infections in Vulnerable Pediatric Populations
edited by Anna Chiara Vittucci and
submission deadline 28 Feb 2027 | Viewed by 52 | Submission Open
Keywords: viral infections; pediatrics; viral load; children; vulnerable children; prevention; complex medical conditions; climate change; prevention strategies
(This special issue belongs to the Section Human Virology and Viral Diseases)
Immune Metabolism and Autophagy in Chronic Viral Infections
edited by Wenli Mu and Anjie Zhen
submission deadline 28 Feb 2027 | Viewed by 19 | Submission Open
Keywords: immune metabolism; autophagy; mitochondria; chronic viral infection; immune exhaustion; viral reservoirs; immunometabolism
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Broad-Spectrum Antiviral Strategies Against Emerging and Re-Emerging Viral Diseases
edited by Yongtao Li
submission deadline 27 Mar 2027 | 1 articles | Viewed by 506 | Submission Open
Keywords: broad-spectrum antivirals; emerging and re-emerging viruses; host-directed therapies; pan-viral inhibitors; antiviral drug discovery; host–virus interactions; viral replication machinery; pandemic preparedness; drug repurposing; viral pathogenesis
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
CRISPR Applications in Plant Virology
edited by
submission deadline 31 Mar 2027 | Viewed by 2191 | Submission Open
Keywords: CRISPR/Cas9; plant virology; virus resistance; genome editing; plant breeding; viral evolution; CRISPR applications; host–virus interactions; crop protection; genome modification
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
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