Advances in Honey Bee Viruses Research

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Invertebrate Viruses".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 1198

Special Issue Editors


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Guest Editor
Institute of Virology, Faculty of Veterinary Medicine, Justus-Liebig-University Giessen, Schubertstrasse 81, 35392 Giessen, Germany
Interests: viral-related diseases of livestock and insects; plus-strand RNA viruses; deformed wing virus; sacbrood virus; chronic bee paralysis virus; picornavirales; dicistroviruses; reverse genetics
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Guest Editor
Austrian Chamber of Agriculture, Schauflergasse 6, 1010 Vienna, Austria
Interests: plus-strand RNA viruses; deformed wing virus; sacbrood virus; chronic bee paralysis virus; diagnostic tests; monclonal antibodies; lateral flow devices; varroa destructor; reverse genetics

Special Issue Information

Dear Colleagues,

We invite you to contribute to this Special Issue of Viruses, focusing on the recent advancements in the study of honey bee viruses. The global spread of Varroa mites has significantly impacted honey bee health, facilitating the transmission and increasing the virulence of viruses such as the deformed wing viruses (DWVs) or the Acute bee paralysis virus–Kashmir bee virus–Israeli acute paralysis virus complex (AKIC). Novel parasite–virus interactions have influenced virus diversity, distribution, and evolution. Similar or unexpected interactions may arise with other known or yet-to-be-identified viruses. Various nonviral pathogens may exacerbate not only the prevalence but also the severity of viral honey bee diseases, potentially playing a role as cofactors in the development of clinical symptoms. There is still a lot that remains unexplored in the viral ecology of bees, especially with regard to the immune system of honey bees and mites.

Until recently, only 23 honey bee viruses have been known, with few linked to disease symptoms or colony health issues. Rarely have Koch's postulates been fulfilled to establish a direct link between pathogen and disease. However, next-generation sequencing (NGS) technologies have led to the discovery of many more viruses in honey bee samples, although their significance to bee health remains largely unknown. These novel viruses include rhabdoviruses, orthomyxoviruses, bunyaviruses, and even DNA viruses, alongside typical insect viruses from the Picornavirales order from families like Iflaviridae and Dicistroviridae. For many newly identified viruses, isolates are non-existent. Some of these viruses have not been confirmed to replicate in honey bees. Understanding their impact on bee colony health, interactions with parasites, bacteria, and other viruses, will take time and effort. Research and new findings on virus transmission from honey bees to other wild pollinators are particularly challenging and concerning.

The discovery of new viruses, reverse genetic systems for honey bee viruses, permanent cell cultures, and advanced cell biology methods promise rapid progress in understanding honey bee pathogens and diseases. These advancements are expected to identify viral virulence factors, cellular receptor molecules, and honey bee defence mechanisms in the near future.

This Special Issue aims to present and summarize the latest discoveries in basic research and advancements in honey bee virus virology, epidemiology, diagnostics, and control. We seek to highlight recent progress in understanding honey bee virus morphology, genome organization, transmission, and evolution. Additionally, this Special Issue will emphasize viral diseases and epidemics in honey bees, their economic impact on beekeeping, and their environmental and agricultural significance. We hope it will draw attention to these critical topics, enhance collaboration among scientists in the field, and showcase current original research.

Prof. Dr. Benjamin J. Lamp
Dr. Kerstin Seitz
Guest Editors

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Keywords

  • honey bee viruses
  • deformed wing virus
  • DWV
  • sacbrood virus
  • SBV
  • chronic bee paralysis virus
  • CBPV
  • acute bee paralysis virus
  • ABPV
  • Israel acute bee paralysis virus
  • IAPV
  • Iflavirus
  • Dicistrovirus
  • rhabdovirus
  • ARV

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Published Papers (1 paper)

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Research

6 pages, 735 KB  
Article
Viruses Infecting Cuban Honey Bees and Evolution of Deformed-Wing-Virus Variants
by Poppy J. Hesketh-Best, Anais R. Luis, Declan C. Schroeder and Stephen J. Martin
Viruses 2026, 18(1), 148; https://doi.org/10.3390/v18010148 - 22 Jan 2026
Viewed by 527
Abstract
Cuba is in a unique situation in which it has a large (220,000 managed colonies) and isolated honey bee population due to a 60+ year ban on the importation of bees. Despite this, the ectoparasitic mite Varroa destructor arrived in 1996, and with [...] Read more.
Cuba is in a unique situation in which it has a large (220,000 managed colonies) and isolated honey bee population due to a 60+ year ban on the importation of bees. Despite this, the ectoparasitic mite Varroa destructor arrived in 1996, and with it came deformed wing virus (DWV). In 2018, an island-wide survey detected varroa and DWV in 91% of colonies. In this study, we conducted a full-virome analysis on some of these samples, along with additional samples collected in 2021. For the first time, we detected two variants of Lake Sinai Virus and confirmed the absence of the normally widespread black queen cell virus in Cuba. We also detected both DWV-A and DWV-B master variants, with DWV-B being the dominant variant. Interestingly, the DWV-B/A recombinant was also detected, indicating that despite Cuba’s isolated nature, the pattern of DWV evolution mirrors that found in the USA and Europe. However, this pattern is not found in neighboring Latin America, China, or Japan, where the DWV-A master variant continues to be dominant. How and why two distinct evolutionary DWV pathways have arisen remain a mystery. Full article
(This article belongs to the Special Issue Advances in Honey Bee Viruses Research)
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