Advances in Understanding Viral Pathogenesis and Host Immune Responses to Arboviruses and Respiratory Viruses
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Animal Viruses".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 55
Special Issue Editors
2. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina
Interests: dengue virus; Zika virus; respiratory syncytial virus; viral immunology; viral pathogenesis; virus–host cell interactions
2. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina
Interests: arboviruses; RNA viruses; chikungunya virus; dengue virus; viral replication; viral genome; virus–host cell interactions
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Arboviruses, including dengue, Zika, chikungunya, and yellow fever viruses, are arthropod-transmitted pathogens that continue to expand their geographic distribution, posing a significant threat to public health worldwide. Despite causing millions of infections each year, effective antiviral treatments and vaccines remain limited for many of them. With global climate change and the increasing spread of arboviruses, there is an urgent need to address the understudied aspects of their pathogenesis to develop effective intervention strategies for future outbreaks.
Respiratory viruses, including influenza virus, rhinovirus, respiratory syncytial virus, parainfluenza virus, metapneumovirus, coronaviruses, and adenoviruses, are the most common causative agents of disease in humans. These viruses are responsible for significant morbidity and mortality, especially in neonates, immunocompromised individuals, and the elderly. Vaccines and antiviral therapy are currently available for only a few of these viruses, which poses a great challenge for continued research on prevention and therapeutic strategies against respiratory viral infections.
With this Special Issue, we aim to explore the pathogenesis of these two important groups of viruses and host immune responses to infections. Understanding viral pathogenesis mechanisms and virus–host immune interactions is crucial for developing safe and effective treatments and vaccines against these viruses with a high impact on global health.
Potential topics of interest for this Special Issue include, but are not limited to, the following:
- Mechanisms of infection and spread: entry, replication, and dissemination and tissue tropism;
- Viral evasion strategies: modulation of innate immune responses and mechanisms of persistence;
- Host factors influencing pathogenesis: genetic and immunological determinants of disease severity and the impact of comorbidities on viral pathogenesis;
- Innate immunity: role of pattern recognition receptors and interferon and cytokine responses;
- Adaptive immunity: T cell responses and immune memory formation, B cell responses, and neutralizing antibodies;
- Cytokine storm and immune dysregulation;
- Immune modulation and host-directed therapies.
Dr. Laura Beatriz Talarico
Dr. Claudia Filomatori
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- arboviruses
- respiratory viruses
- viral pathogenesis
- host immune responses
- innate immunity
- adaptive immunity
- viral immune evasion
- cytokine storm
- interferon response
- viral replication
- viral transmission
- immunopathology
- neutralizing antibodies
- host–virus interactions
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