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Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Extracellular Vesicles for Targeted Delivery

edited by

Beáta Soltész

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1455 | Submission Open

Keywords: computational approaches; drug delivery; engineered exosomes; exosomes; experimental approaches; extracellular vesicle-based delivery; extracellular vesicles; immunotherapy; nanomedicine; therapeutic cargo; therapy

(This special issue belongs to the Section Biologics and Biosimilars)

Advanced Nanomaterials for Drug Delivery, 2nd Edition

edited by

Roxana Cristina Popescu

and

Diana Savu

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1375 | Submission Open

Keywords: nanomaterials; drug delivery systems; cancer therapy; antimicrobial applications; antiviral applications

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Next-Generation Biomaterials for Oral Healthcare: Focus on Regenerative and Delivery Functions

edited by

Giuseppina Nocca

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1157 | Submission Open

Keywords: transmucosal drug delivery; transmucosal formulations; excipients; nanotechnology; drug release

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Bioactive Molecules for Targeted Cancer Therapy and Delivery Innovations

edited by

Cristian O. Salas

and Felipe Andrés Oyarzún-Ampuero

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1064 | Submission Open

Keywords: bioactive molecules; targeted therapy; angiogenesis inhibitors; signal transduction inhibitors; nano and micromedicines; drug delivery; spatial and temporal drug release

(This special issue belongs to the Section Biologics and Biosimilars)

Bioactive Hydrogels as Multifunctional Dressing Materials

edited by

Jagoda Kurowiak

and Tomasz Klekiel

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1062 | Submission Open

Keywords: biocompatible hydrogels; functional materials; natural polymers; biohydrogels; dressings; hard-to-heal wounds; burns; bedsores; pharmaceuticals; active substances; anti-inflammatory and antibacterial drugs

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Natural Macromolecule-Based Nanocarriers for Drug Delivery

edited by

Lipeng Qiu

submission deadline 31 Dec 2025 | 1 articles | Viewed by 894 | Submission Open

Keywords: macromolecules; polysaccharides; proteins; nucleic acids; lipids; nanocarrier; drug delivery; targeted delivery; controlled release

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Drug Delivery Systems for Ocular Diseases

edited by

Gonzalo Carracedo

and

Maria Vivero-Lopez

submission deadline 31 Dec 2025 | 1 articles | Viewed by 860 | Submission Open

Keywords: ocular diseases; contact lens delivery; drug delivery systems; nanotechnology

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advancements in AI and Pharmacokinetics

edited by

Raj Sewduth

submission deadline 31 Dec 2025 | 1 articles | Viewed by 730 | Submission Open

Keywords: AI in nanomedicine; drug targeting; pharmacokinetics; pharmacodynamics; drug– receptor interactions

(This special issue belongs to the Section Drug Targeting and Design)

Nanotechnology Advances for Breast Cancer Treatment

edited by Marlus Chorilli, Marcela Tavares Luiz and Pietro Rosemeire Cristina Linhari Rodrigues

submission deadline 31 Dec 2025 | 1 articles | Viewed by 697 | Submission Open

Keywords: active targeting; breast cancer; cancer therapy; drug delivery systems; nanoparticles; nanosystems

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Application of Polymeric Micelles for Drug and Gene Delivery, 2nd Edition

edited by

Stanislav Rangelov

and

Emi Haladjova

submission deadline 31 Dec 2025 | 1 articles | Viewed by 622 | Submission Open

Keywords: polymeric micelles; micelleplexes; drug delivery; gene delivery; drug release; nanomedicine; gene therapy; theranostics

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Unlocking Cancer Treatment: Harnessing Lipid Nanocarriers for Precision Drug Delivery

edited by Joydeb Majumder

submission deadline 31 Dec 2025 | Viewed by 303 | Submission Open

Keywords: cancer therapy; nano therapeutics; lipid nanoparticles; drug delivery; targeted delivery; nanomedicine

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Cutting-Edge 3D Printing Technology for Drug Delivery and Tissue Engineering

edited by

Eliana Aparecida de Rezende Duek

, Moema Hausen and

Cecília de Barros

submission deadline 31 Dec 2025 | Viewed by 302 | Submission Open

Keywords: additive manufacturing; smart materials; bioactive molecules; drug delivery systems; tissue engineering; biomaterials for tissue healing; 3D scaffolds; cell therapy with biomaterials

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Microfluidic Assembly of Nanocomplexes for Drug and Gene Delivery

edited by Tiago Albertini Balbino and

Ismail Eş

submission deadline 31 Dec 2025 | Viewed by 276 | Submission Open

Keywords: microfluidics; nanocomplex assembly; drug delivery; gene delivery; polymer nanoparticle; lipid nanoparticle; process optimization; mRNA vaccine delivery

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Functional Polymers for Targeted Therapeutics and Gene Delivery

edited by Łukasz Sieroń and

Emanuela Fabiola Craparo

submission deadline 31 Dec 2025 | Viewed by 264 | Submission Open

Keywords: polymer; nanoparticle; nucleic acid delivery; targeted therapy; targeted delivery; gene therapy

(This special issue belongs to the Section Gene and Cell Therapy)

Advances and Challenges in Nanomedicine: Translating Nanotechnology into Therapeutics for Cancer, Neurodegenerative, and Infectious Diseases

edited by

Giovanna Della Porta

and

Erwin Pavel Lamparelli

submission deadline 31 Dec 2025 | Viewed by 246 | Submission Open

Keywords: nanomedicine; targeted delivery; gene therapies; immunotherapies; cancer; infectious diseases; neurological disorders

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Multifunctional Hydrogels for Controlled Release of Bioactive Molecules

edited by

Diana C. Silva

Ana Paula Serro

and

Maria Vivero-Lopez

submission deadline 31 Dec 2025 | Viewed by 224 | Submission Open

Keywords: multifunctional hydrogels; biodegradable hydrogels; antimicrobial hydrogels; smart hydrogels; stimuli-responsive hydrogels; therapeutic hydrogels; nanogels; drug delivery; local drug delivery; controlled release; drug carriers; bioactive molecules; bioactive materials; biocompatible materials; hydrogel characterization; ex vivo and in vivo evaluation

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Multifunctional Nanomaterials in Drug Delivery

edited by

Ranjit De

submission deadline 31 Dec 2025 | Viewed by 206 | Submission Open

Keywords: nanomaterials; bioavailability; targeting efficiency; controlled release; drug delivery

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Design of Hydrogels for Drug Delivery

edited by

Luis Morales-Quintana

and

Bustos Daniel

submission deadline 31 Dec 2025 | Viewed by 199 | Submission Open

Keywords: drug delivery; controlled release; smart hydrogels; computational modelling of hydrogels; molecular simulations of hydrogels; bioresponsive systems; hydrogel fabrication techniques

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advances in Radiopharmaceuticals: Enhancing Targeted Delivery, Disease Diagnosis, and Therapeutic Applications

edited by Kuan Hu and Volkan Tekin

submission deadline 31 Dec 2025 | Viewed by 167 | Submission Open

Keywords: radiopharmaceuticals; radiotherapy; diagnosis; therapy; targeting delivery

(This special issue belongs to the Section Clinical Pharmaceutics)

Biopolymer Nanoparticles for Targeted Therapy in Cardiovascular Diseases

edited by Lino Sánchez-Segura and Silvio Zaina

submission deadline 31 Dec 2025 | Viewed by 160 | Submission Open

Keywords: nanoparticles; biopolymers; drug-load; drug delivery; target; cardiovascular disease; therapy

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Electrospun Fibers, Tissue Engineering, and Drug Delivery: Strategies and Potential Solutions for a Complex Issue

edited by Adrienn Kazsoki and

Constantinos Voniatis

submission deadline 31 Dec 2025 | Viewed by 159 | Submission Open

Keywords: electrospinning; fibrous mesh; drug delivery systems; biodegradable membranes; nanofibers; potential drug candidates for nanofibrous dosage forms

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Development of Oncolytic Viruses as Platforms for Drug Delivery to Cancers

edited by

Alberto Reale

and

Jennifer Altomonte

submission deadline 31 Dec 2025 | Viewed by 112 | Submission Open

Keywords: oncolytic viruses; cancer; targeted drug delivery; immunotherapy; gene therapy; tumor microenvironment

(This special issue belongs to the Section Gene and Cell Therapy)

Innovative Therapeutic Delivery Strategies for Brain Tumors: Overcoming Barriers and Modulating the Tumor Microenvironment

edited by

and

submission deadline 31 Dec 2025 | Viewed by 93 | Submission Open

Keywords: brain tumors; drug delivery; blood– brain barrier; immunotherapy; gene therapy; tumor microenvironment; nanoparticles

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advanced Research on Transdermal Drug Delivery

edited by

and

submission deadline 31 Dec 2025 | Viewed by 90 | Submission Open

Keywords: transdermal drug delivery; skin drug delivery; percutaneous drug delivery; topical drug delivery; microneedles; patches; hydrogels; creams

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Paediatric and Neonatal Specific Dosage Forms and Administration

edited by

Smita Salunke

and Fiona O'Brien

submission deadline 31 Dec 2025 | Viewed by 88 | Submission Open

Keywords: excipients safety; non-oral drug delivery; oral drug delivery; paediatric dosage forms; neonatal dosage forms; drug administration; age-appropriate formulations

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Recent Advances in Drug Delivery Using AI and Machine Learning

edited by

Glen S. Kwon

Hugh D. C. Smyth

, Chinmay S. Potnis and Rebeca T. Stiepel

submission deadline 31 Dec 2025 | Viewed by 73 | Submission Open

Keywords: nanoparticle drug delivery; artificial intelligence (AI); machine learning (ML); predictive modelling; targeted drug delivery; nanomedicine; excipient optimization; personalized drug formulations; computational drug design; AI-driven drug development

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Innovative Drug Delivery Strategies Across Biological Barriers: From Organ-on-a-Chip Models to Nanopharmaceuticals

edited by

Franciska Erdő

Amir Fahmi

and

Romána Zelkó

submission deadline 31 Dec 2025 | Viewed by 71 | Submission Open

Keywords: drug delivery systems; biological barriers; blood– brain barrier (BBB); organ-on-a-chip; lab-on-a-chip; nanopharmaceuticals; 3D printing in pharmaceutics; targeted delivery; transdermal delivery; nasal drug delivery; ocular drug delivery; pulmonary delivery; gene therapy; nanocarriers; personalized medicine; bioavailability enhancement; transporter-mediated drug delivery; in vitro models; barrier modeling; patient-centric formulations

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Overcoming Biological Barriers: Novel Strategies in Drug Delivery

edited by

Bárbara Sánchez-Dengra

and

Isabel Gonzalez-Alvarez

submission deadline 31 Dec 2025 | Viewed by 59 | Submission Open

Keywords: biological barriers; drug delivery systems; permeability

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Innovations in Ungual and Dermal Drug Delivery Systems for Localized Therapies

edited by

Letícia Scherer Koester

and

Helder Teixeira

submission deadline 31 Dec 2025 | Viewed by 54 | Submission Open

Keywords: nano-based formulations; hydrogel-based formulations; 3D-printed formulations; films; biocompatibility; ungual; dermal; in vitro release testing (IVRT); in vitro permeation testing (IVPT)

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Carbon Dot-Based Drug Delivery Systems for Targeted Therapy

edited by

Rosana Badía

and

Alfonso Fernández-González

submission deadline 31 Dec 2025 | Viewed by 53 | Submission Open

Keywords: carbon dots (CDs); drug delivery systems; targeted therapy; nanocarriers; controlled release; intracellular delivery; nanomedicine; gene delivery; fluorescent nanomaterials; bioimaging; stimuli-responsive release; smart drug carriers

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Gene- and Peptide-Based Therapeutics for Neurodegenerative Disorders

edited by

Ramona Meanti

and Chiara Lucchi

submission deadline 31 Dec 2025 | Viewed by 53 | Submission Open

Keywords: neurodegenerative diseases; gene therapy; peptide-based therapeutics; targeted drug delivery; neuroprotection

(This special issue belongs to the Section Gene and Cell Therapy)

Advances and Challenges in Nasal Formulation Developments, 3rd Edition

edited by

Daisuke Inoue

submission deadline 31 Dec 2025 | Viewed by 53 | Submission Open

Keywords: nasal formulations; intranasal dissolution and permeation; mucosal absorption; excipients for nasal formulations; in vitro dissolution system; in vivo nasal dissolution and absorption

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Recent Advances in 3D Printing of Pharmaceutical Dosage Forms

edited by

Mladena Lalic-Popovic

and Veljko Krstonošić

submission deadline 31 Dec 2025 | Viewed by 50 | Submission Open

Keywords: drug delivery; 3D printing; additive manufacturing; personalized medicine; pharmaceutical excipients; polymers; biopolymers; hot melt extrusion (HME); fused deposition modeling (FDM); selective laser sintering (SLS)

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Modern Formulation and Applications of Probiotics

edited by

Ildikó Bácskay

and Dávid Sinka

submission deadline 31 Dec 2025 | Viewed by 38 | Submission Open

Keywords: probiotics; nanoformulation; microencapsulation; targeted delivery; next-generation probiotics; synbiotics; gut– brain axis; personalized medicine

(This special issue belongs to the Section Biologics and Biosimilars)

The Integration of Novel Approaches in Laboratory Medicine into Precision Pharmacotherapy

edited by

Gellért Balázs Karvaly

submission deadline 31 Dec 2025 | Viewed by 34 | Submission Open

Keywords: therapeutic drug monitoring; pharmacokinetics; pharmacodynamics; bioinformatics; clinical chemistry; mass spectrometry; immunology; clinical genetics; antiinfectives; artificial intelligence

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Micro- and Nanotechnology Empowering Combination Therapy of Cancer and Chronic Diseases

edited by

Rui Xue Zhang

submission deadline 31 Dec 2025 | Viewed by 27 | Submission Open

Keywords: nanotechnology; drug delivery; computer-aided design; nanomedicine; hydrogel; long-acting injectable; controlled drug release; combination therapy; bioavailability; biological barrier

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Innovative Nanomaterials and Metal Complexes as a Platform for Targeted Therapeutics

edited by Željko Prijović

submission deadline 31 Dec 2025 | Viewed by 15 | Submission Open

Keywords: targeted therapeutics; nanomaterials; metal complexes; drug delivery; biocompatibility; stimuli-responsive; multifunctional nanosystems; clinical translation

(This special issue belongs to the Section Drug Targeting and Design)

Nanocarriers and Delivery Systems for Next-Generation Nanomedicine Therapies

edited by

Wei Huang

submission deadline 31 Dec 2025 | Viewed by 7 | Submission Open

Keywords: nanocarriers; targeted delivery systems; stimuli-responsive materials; co-delivery systems; theranostic nanoplatforms; clinical translation

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Nano-Drug Delivery Systems: Tackling Cancer Metabolism and Drug Resistance

edited by

Odília Queirós

submission deadline 31 Dec 2025 | Viewed by 7 | Submission Open

Keywords: nano-drug delivery systems; tumor microenvironment; cancer metabolism; metabolic reprogramming; drug resistance; targeted therapy; combination therapy

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Natural Product Pharmaceuticals, 2nd Edition

edited by

Maria Rosaria Lauro

submission deadline 31 Dec 2025 | Viewed by 4 | Submission Open

Keywords: pre-formulation and formulation studies; natural compounds; herbal extracts; chemical– physical and technological studies; extraction methods; stability and stabilization; in vitro and in vivo biological activities; pharmacokinetics and pharmacological studies; analytical techniques

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Innovative Approaches in Skin Formulation Development and Characterization: Scientific Foundations for Regulatory Transformation

edited by

Snezana Savic

and

Ivana Pantelić

submission deadline 31 Dec 2025 | Viewed by 4 | Submission Open

Keywords: regulatory-driven formulation development; topical products; transdermal drugs; nano/microstructured delivery systems; characterization techniques; skin models; in vitro studies; in vivo studies; in silico modeling; AI

(This special issue belongs to the Section Physical Pharmacy and Formulation)

3D Printing—Current Pharmaceutical Applications and Future Directions

edited by Ivana M. Cotabarren,

Sanjay Garg

and Loreana C. Gallo

submission deadline 10 Jan 2026 | 4 articles | Viewed by 3135 | Submission Open

Keywords: 3D printing; pharmaceutical products; 3D printers; personalized drug delivery; additive manufacturing; new materials for 3D printing

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Smart Materials for Advanced Drug Delivery Systems and Pharmaceutical Applications

edited by

Milena A. Vega

submission deadline 20 Jan 2026 | 2 articles | Viewed by 1273 | Submission Open

Keywords: smart materials; drug delivery systems; pharmaceutical applications; responsive materials; hydrogels; functionalized nanoparticles; targeted drug release; biological stimuli

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advances in Pharmacokinetics of Targeted Anti-Cancer Drugs

edited by

Marios Spanakis

and Retheesh S. Thankan

submission deadline 20 Jan 2026 | Viewed by 53 | Submission Open

Keywords: pharmacokinetics; targeted anti-cancer drugs; in vivo models of PK studies; personalized medicine; drug design

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Ocular Drug Delivery System

edited by Xin Fan and

Elena Sánchez-López

submission deadline 20 Jan 2026 | Viewed by 42 | Submission Open

Keywords: drug delivery; nanoparticles; controlled release; hydrogels; liposomes; microneedle arrays

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Magnetic Materials for Biomedical Applications

edited by

Carlos O. Amorim

submission deadline 20 Jan 2026 | Viewed by 33 | Submission Open

Keywords: magnetic materials; magnetic nanoparticles; nanomedicine; nanotechnology; theranostics; drug delivery systems; magnetic gels; magnetic hyperthermia; magnetic imaging

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Nanoparticles for Glioblastoma Therapy

edited by Shambhavi Pandey and

Benjamí Oller-Salvia

submission deadline 20 Jan 2026 | Viewed by 25 | Submission Open

Keywords: nanoparticles; blood– brain barrier; gene delivery; glioblastoma; cancer stem cells; biomaterials

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Drug Formulation Design and Pharmacokinetics for the Treatment of Skin Diseases

edited by

Marcelle Silva-Abreu

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1735 | Submission Open

Keywords: pharmacokinetic studies of topical and transdermal therapies; advanced techniques for assessing drug penetration and distribution; optimization of therapeutic efficacy and safety profiles; dermatological drug delivery; topical formulations; skin pharmacokinetics; drug penetration; transdermal patches; creams and gels

(This special issue belongs to the Section Biopharmaceutics)

Advances in Physiologically Based Pharmacokinetic (PBPK) Modeling and Applications

edited by

Dong‑Gyun Han

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1581 | Submission Open

Keywords: physiologically based pharmacokinetic (PBPK) modeling; IVIVE; pharmacokinetics; ADME; modeling and simulation; PK/PD; biopharmaceutics; quantitative systems pharmacology

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Synergistic Nanomedicines: Integrating Chemotherapy and Phototherapy for Enhanced Cancer Treatment

edited by Nasrin Hooshmand

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1152 | Submission Open

Keywords: nanomaterial; nanomedicine; chemo-photothermal therapy; cancer; drug delivery

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Displaying special issue 351-400 on page 8 of 9.

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