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Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Improving the Bioavailability and Solubility of Pharmaceutical Formulations

edited by

Zoltan Ujhelyi

, Dóra Kósa and

Ágota Pető

submission deadline 10 Mar 2026 | 7 articles | Viewed by 15085 | Submission Open

Keywords: bioavailability enhancement; drug delivery systems; in vitro and in vivo evaluation methods; therapeutic effectiveness; pharmaceutical innovations; nanoformulations; surfactants; poorly soluble drugs

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Nanoformulations for Local Treatment of Cancer, Infections and Wounds

edited by

Orlando David Henrique dos Santos

Glenda Nicioli da Silva

and Tatiane Roquete Amparo

submission deadline 10 Mar 2026 | 5 articles | Viewed by 9599 | Submission Open

Keywords: nanoformulation; local application; cancer; infections; wound healing; nanotechnology; topical application; intravesical application; intratumoral administration; gel; nanoemulsion; nanoparticle

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Recent Advances in 3D Bioprinting for Drug Delivery and Tissue Engineering

edited by

Jhaleh Amirian

submission deadline 10 Mar 2026 | Viewed by 467 | Submission Open

Keywords: 3D printing; bioink; drug delivery system; personalized medicine; medical devices; tissue engineering

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Recent Advances in Antimicrobial Drug Delivery

edited by

Sourav Das

and

Tamás Kőszegi

submission deadline 10 Mar 2026 | Viewed by 48 | Submission Open

Keywords: antimicrobial drug delivery; nanoparticles; controlled release; targeted therapy; antimicrobial resistance; nanomedicine; smart drug delivery systems; surface modification; biofilm treatment; advanced drug delivery strategies

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Antimicrobial Peptides as Promising Therapeutic Agents

edited by Axel Hollmann and Paulo C Maffía

submission deadline 15 Mar 2026 | Viewed by 349 | Submission Open

Keywords: antimicrobial peptides; peptide– membrane interactions; antiviral peptides; mechanism of action; synergy; multi-drug-resistant bacteria; immune modulation

(This special issue belongs to the Section Drug Targeting and Design)

Emerging Trends and Advancements in Anticancer Photodynamic Therapy: Innovative Delivery Systems, Translational Insights, and Breakthroughs

edited by Anine Crous and

Blassan George

submission deadline 15 Mar 2026 | Viewed by 252 | Submission Open

Keywords: photodynamic therapy (PDT); anticancer therapy; photosensitizers; nanotechnology; immune modulation; imaging-guided therapy; combination therapies; preclinical studies; clinical translation; light-based therapy

(This special issue belongs to the Section Clinical Pharmaceutics)

New Strategies in Gene and Cell Therapy for Neurological Disorders

edited by

Jubayer Hossain

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1903 | Submission Open

Keywords: gene and cell therapy; neurodegenerative diseases; neurodevelopmental disorders; neuropsychiatric conditions; CNS tumors; trauma and injury in the CNS; blood– brain barrier; neuroimmunology and immunomodulation; peripheral nervous system disorders; regenerative medicine

(This special issue belongs to the Section Gene and Cell Therapy)

Nanotechnology in the Treatment of Neglected Parasitic Diseases

edited by

Eduardo Ricci Junior

and

Ana Paula dos Santos Matos

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1105 | Submission Open

Keywords: neglected disease; nanotechnology; parasitic disease; modified release; sustained release; nanoparticles; liposomes; nanoemulsions

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Antibacterial Applications of Novel Nanoscale Biocompounds

edited by

Francisca Acevedo

and

Eulàlia Sans Serramitjana

submission deadline 20 Mar 2026 | Viewed by 630 | Submission Open

Keywords: antimicrobial agent delivery; biopolymers; electrospun fibers/scaffolds; drug– polymer– fiber interactions; biofilms; microbial resistance; antimicrobial nanoparticles; nanobiomolecules; nanocoatings; functionalized nanomaterials

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Biodegradable Polymer Platforms for Long-Acting Drug Delivery

edited by

Leah M. Johnson

and Archana Krovi

submission deadline 20 Mar 2026 | Viewed by 122 | Submission Open

Keywords: sustained release systems; long-acting drug delivery; controlled drug delivery; biodegradable polymers; long-acting injectables; injectable depots; nanoparticles and microparticles; long-acting implants; polymer– drug conjugates; parenteral formulations

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Vesicle-Based Drug Delivery Systems

edited by

Luciano Benedini

and Paula Messina

submission deadline 20 Mar 2026 | Viewed by 57 | Submission Open

Keywords: liposomes; exosomes; extracellular vesicles; niosomes; polymersomes; active and passive targeting; pharmacokinetics; isolation/synthesis; functionalization; modified release

(This special issue belongs to the Section Drug Delivery and Controlled Release)

3D Printing in Bioengineering and Pharmaceutical Manufacturing

edited by Darren J. Player

submission deadline 20 Mar 2026 | Viewed by 35 | Submission Open

Keywords: 3D printing; 3D-bioprinting; precision medicine; personalized medicine; bioengineering; pharmaceutical manufacturing

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Personalized Medicine in Clinical Pharmaceutics

edited by

Sandy Jeong Rhie

submission deadline 20 Mar 2026 | Viewed by 17 | Submission Open

Keywords: personalized medicine; precision pharmaceutics; therapy optimization; pharmacogenomics; 3D printing; nanotechnology; targeted drug delivery; individualized therapy; patient-specific formulations; adaptive drug delivery; clinical pharmaceutics; pharmaceutical care

(This special issue belongs to the Section Clinical Pharmaceutics)

Formulation Design of Lipid Nanoparticles for Pharmaceutical Applications

edited by

Shyamal Das

and Md. Mahbub Hassan

submission deadline 27 Mar 2026 | 1 articles | Viewed by 3554 | Submission Open

Keywords: lipid nanoparticles; drug delivery; formulation; stability; controlled release; regulatory challenges; quality control

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Biopolymer Materials for Wound Healing, 3rd Edition

edited by

Gorka Orive

and

Martin Federico Desimone

submission deadline 30 Mar 2026 | 2 articles | Viewed by 2208 | Submission Open

Keywords: biopolymer; wound healing; scaffolds; biomaterials; tissue engineering; regenerative medicine; drug delivery

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Feature Reviews in Pharmaceutical Technology, Manufacturing and Devices

edited by Thierry Vandamme

submission deadline 30 Mar 2026 | 1 articles | Viewed by 582 | Submission Open

Keywords: pharmaceutical technology; drug manufacturing; nanotechnology; continuous manufacturing; drug delivery devices; 3D printing; artificial intelligence; wearable devices; process optimization

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Extracellular Matrix and Vesicles as Immunomodulatory Therapeutics

edited by

Amiq Gazdhar

Hector Capella-Monsonís

, William D’Angelo and

Ana Isabel Flores

submission deadline 30 Mar 2026 | Viewed by 379 | Submission Open

Keywords: extracellular matrix; extracellular vesicles; inflammation; immunomodulation; regenerative medicine; drug delivery; clinical translation

(This special issue belongs to the Section Gene and Cell Therapy)

Application of Electrospinning Technology in Pharmaceutical Engineering

edited by

Wanderley Pereira de Oliveira

and

Monica Lopes Aguiar

submission deadline 30 Mar 2026 | Viewed by 44 | Submission Open

Keywords: electrospinning; nanofibers; drug delivery; pharmaceutical engineering; controlled release; solubility enhancement; tissue engineering; wound healing; biomedical applications

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Development of Nucleic Acid Delivery System

edited by

Wei Huang

submission deadline 31 Mar 2026 | 5 articles | Viewed by 28972 | Submission Open

Keywords: nucleic acid delivery system; nonviral vectors; gene delivery; siRNA delivery; gene editing system delivery; mRNA delivery; codelivery of small-molecule drugs and nucleic acids; clinical transformation of nucleic acid delivery systems

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Biotechnology Applications and Innovative Approaches for Cancer Prevention and Treatment (BIO-APP)

edited by

and

submission deadline 31 Mar 2026 | 3 articles | Viewed by 8046 | Submission Open

Keywords: applied biochemistry; biotechnologies; cancer; drug delivery; multitarget ligands; theranostics; biomarkers; point-of-care testing; sensitive nanomaterials

(This special issue belongs to the Section Biologics and Biosimilars)

Multifunctional Hydrogels for Controlled Drug Delivery

edited by

Cheng Hu

submission deadline 31 Mar 2026 | 1 articles | Viewed by 4023 | Submission Open

Keywords: multifunctional hydrogels; drug delivery; biomedical applications; targeted release; therapeutic effects

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Application of Silver Nanoparticles in Cancer Treatment

edited by

Serena Mazzucchelli

and Francesco Ragonese

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1682 | Submission Open

Keywords: silver nanoparticles; nanomedicine; nanotechnology; cancer therapy; cancer diagnostics; cancer theranostics; tumor targeting; drug delivery systems; in vitro studies; in vivo studies

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Nasal Nanotechnology: What Do We Know and What Is Yet to Come?

edited by Rosario Pignatello and

Teresa Musumeci

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1383 | Submission Open

Keywords: nasal drug delivery; polymeric and/or lipid nanocarriers; rhinitis; brain targeting; vaccines; nose-to-brain drug delivery; functionalization; ex vivo and in vivo studies; cytocompatibility/cytotoxicity; mucoadhesion; mucosal permeation

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Natural Innovations in Pharmaceutical Formulation: From Traditional Remedies to Modern Drug Carriers

edited by

Titus Vlase

submission deadline 31 Mar 2026 | Viewed by 346 | Submission Open

Keywords: formulation science; natural products; natural compounds; drug carriers; novel drug delivery platforms

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Formulation, Characterization, and Performance Testing of Topical Semisolid Products

edited by

Michael Roberts

and Seeprarani Rath

submission deadline 31 Mar 2026 | Viewed by 298 | Submission Open

Keywords: formulation of topical semisolid dosage forms; characterization of topical semisolid dosage forms; microstructure; in vitro release and permeation testing; bioavailability and bioequivalence; topical and transdermal delivery; quality-by-design

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Recent Advances in Nucleic Acid-Based Therapeutics, Vaccines, and Drug Delivery Vehicles

edited by

Samantha Meenach

and Ting-Yu Shih

submission deadline 31 Mar 2026 | Viewed by 291 | Submission Open

Keywords: immunotherapy; nucleic acid-based therapeutics and delivery; RNA vaccines; biomaterials; nanomaterials; autoimmune and neurological disorders’ treatment

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Dendrimers in Nanomedicine: Recent Advances

edited by

Anne-Marie Caminade

submission deadline 31 Mar 2026 | Viewed by 282 | Submission Open

Keywords: dendrimers; dendritic nanostructures; biological properties; diagnosis; imaging agents; carriers; drug delivery; drug therapy; nanomedicine

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Bio-Nanoparticle Systems for Brain Drug Delivery

edited by

Valentina Pagliara

and

Raffaella D'Auria

submission deadline 31 Mar 2026 | Viewed by 270 | Submission Open

Keywords: bio-nanoparticles; brain drug delivery; blood-brain barrier; neurological disorders; targeted nanomedicine

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Polymeric Films as a Multipurpose Drug Delivery System: Application, Properties, Preparation and Evaluation

edited by

Jurga Bernatoniene

and

Yuliia Maslii

submission deadline 31 Mar 2026 | Viewed by 255 | Submission Open

Keywords: drug delivery system; polymers; polymeric films; physicochemical and texture characteristics; film production techniques; controlled and sustained release; adhesion; bioavailability; formulation; evaluation

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Combining Ultrasound and Microbubbles/Nanobubbles for Enhancing the Effects of Cancer Therapies

edited by

Yi-Ju Ho

and

Deepa Sharma

submission deadline 31 Mar 2026 | Viewed by 236 | Submission Open

Keywords: ultrasound; immunotherapy; radiation therapy; chemotherapy; micro/nano-bubble; cancer therapeutics; drug delivery

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Peptide Polymer Delivery Systems for Antibacterial and Immunomodulatory Applications

edited by Hashem Etayash

submission deadline 31 Mar 2026 | Viewed by 197 | Submission Open

Keywords: antimicrobial peptides; host defense peptides; bacterial infection; biofilms; immunomodulatory agents; drug resistance; antibiotics; surafe-tethered peptides; peptide formulation; peptide polymers

(This special issue belongs to the Section Biologics and Biosimilars)

Targeted Drug Delivery in Brain Tumor Microenvironments

edited by

Chiara Bastiancich

and Phoebe McCrorie

submission deadline 31 Mar 2026 | Viewed by 91 | Submission Open

Keywords: neuro-oncology; drug delivery; tumour microenvironment; targeted drug delivery; glioblastoma; medulloblastoma

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Novel Strategies for Enhancing Oral Bioavailability

edited by

Naibo Yin

and

Paul William Richard Harris

submission deadline 31 Mar 2026 | Viewed by 82 | Submission Open

Keywords: oral; formulation; delivery system; chemical modification; pro-drug; analogue

(This special issue belongs to the Section Biopharmaceutics)

Microneedle-Mediated Transdermal Delivery of Bio-Macromolecular Drugs

edited by Guangsheng Du and Li Deng

submission deadline 31 Mar 2026 | Viewed by 79 | Submission Open

Keywords: microneedle; transdermal delivery; dermal delivery; bio-macromolecular drugs; minimally invasive; skin delivery; therapeutic biologics

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Ultrasound‑Enhanced Drug Delivery: Applications and Therapeutic Advances

edited by

Gail Ter Haar

and

Petros Mouratidis

submission deadline 31 Mar 2026 | Viewed by 77 | Submission Open

Keywords: therapeutic ultrasound; high‑intensity focused ultrasound (HIFU); focused ultrasound surgery (FUS); histotripsy; sonoporation; sonodynamic therapy; drug delivery; microbubbles; nanoparticles; cancer; neurodegenerative conditions

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Biomaterials for Oral and Dental Drug Delivery

edited by

Magdalena Paczkowska-Walendowska

and

Judyta Cielecka-Piontek

submission deadline 31 Mar 2026 | Viewed by 75 | Submission Open

Keywords: oral drug delivery; dental drug delivery; biomaterials; mucoadhesive systems; tissue regeneration; periodontal therapy

(This special issue belongs to the Section Drug Delivery and Controlled Release)

New Approach Methodologies in Biopharmaceutics: Towards a More Humane Drug Development

edited by

Miguel Ángel Cabrera-Pérez

, Daniel Hachim and

Mauricio A. García

submission deadline 31 Mar 2026 | Viewed by 71 | Submission Open

Keywords: biopharmaceutics; new approach methodologies; model and simulations; organoids; organ-on-a-chip; biorelevant in vitro dissolution; In vitro permeability; effect of excipients; biopharmaceutic-oriented drug development

(This special issue belongs to the Section Biopharmaceutics)

Design and Evaluation of Pharmaceutical Co-Crystallization: Integration of Structural Analysis and Pharmacodynamic Assessment

edited by

Dezhi Yang

and Li Zhang

submission deadline 31 Mar 2026 | Viewed by 70 | Submission Open

Keywords: pharmaceutical co-crystals; structural analysis; pharmacodynamic assessment; crystal engineering; drug solubility enhancement; structure– property relationships; computational screening; bioavailability; solid-state characterization; rational drug design

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Emerging Stimuli-Responsive Nanoparticles for Bioactive Delivery

edited by

Marc Schneider

and Sangeun Lee

submission deadline 31 Mar 2026 | Viewed by 43 | Submission Open

Keywords: disease microenvironment; smart nanoparticles; biofunctional nanomedicine

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Biomedical Applications: Advances in Bioengineering and Drug Delivery, 2nd Edition

edited by María Carolina Otero and

Yusser Olguín

submission deadline 31 Mar 2026 | Viewed by 41 | Submission Open

Keywords: biomedicine; tissue engineering; biomaterials; drug carrier; biological therapy

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Biological Barriers in Health and Disease, 2nd Edition

edited by

Neuhaus Winfried

Gert Fricker

and

Mária A. Deli

submission deadline 31 Mar 2026 | Viewed by 40 | Submission Open

Keywords: drug transport; transport protein regulation; blood– brain barrier; epithelial barriers; gut barrier; respiratory barriers; blood– saliva barrier; cell culture; organoid and chip models; biological barriers and pathological changes; protection of biological barriers in diseases; targeted drug delivery systems and nanoparticles to cross barriers

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Therapeutic Drug Monitoring for Individualized Cancer Therapy

edited by Petra Turčić and Lu Turković

submission deadline 31 Mar 2026 | Viewed by 31 | Submission Open

Keywords: personalized medicine; pharmacometrics; population pharmacokinetics and pharmacodynamics (PK-PD); nonlinear mixed-effects modeling (NONMEM); targeted anticancer drugs; clinical pharmacy and pharmacology; kinase inhibitors; monoclonal antibodies (mAbs); bioanalytical method development and validation; (non-)adherence

(This special issue belongs to the Section Clinical Pharmaceutics)

Oligonucleotide Aptamers for Diagnostics and Therapy

edited by

Claudia Riccardi

and

Ettore Napolitano

submission deadline 31 Mar 2026 | Viewed by 24 | Submission Open

Keywords: aptamers; oligonucleotides; therapy; diagnostics; targeted drug delivery; molecular recognition; aptamer engineering; protein– aptamer interactions; aptamer-based nanotechnology

(This special issue belongs to the Section Gene and Cell Therapy)

Combatting Infections: The Role of Antibacterial Natural Products and Nanoparticles

edited by Iwona Skiba-Kurek and

Carla Zannella

submission deadline 31 Mar 2026 | Viewed by 10 | Submission Open

Keywords: multidrug-resistant bacteria; antibacterial compounds; antimicrobial nanoparticles; silver; zinc and copper nanoparticles; skin and wound infections; antibacterial mushroom extracts; dressings

(This special issue belongs to the Section Drug Targeting and Design)

Shape Memory Polymers for Drug Delivery and Tissue Engineering

edited by

Silvia Pisani

submission deadline 31 Mar 2026 | Viewed by 10 | Submission Open

Keywords: shape memory polymers; smart biomaterials; drug delivery system; tissue engineering; regenerative medicine; controlled release; biomedical applications; electrospinning; 3D printing; microfluidic

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Nucleic-Acid-Based Strategies and Nanotechnology Applications for Targeted Therapy, 2nd Edition

edited by

Andrea Patrizia Falanga

submission deadline 31 Mar 2026 | Viewed by 5 | Submission Open

Keywords: nucleic acids; drug delivery; nanomedicine; biotechnology; material science

(This special issue belongs to the Section Drug Targeting and Design)

Nanotechnology and Cell Therapies for Ocular Diseases

edited by

Raid Alany

and

Ovidiu Samoilă

submission deadline 31 Mar 2026 | Viewed by 5 | Submission Open

Keywords: nanotechnology; limbal stem cells; cell cultivation techniques; eye barriers; drug delivery systems; retinal degenerations

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Microparticle Platforms for Respiratory Delivery

edited by

Dae Hwan Shin

and Hye Jin Lee

submission deadline 31 Mar 2026 | Viewed by 4 | Submission Open

Keywords: pulmonary drug delivery; inhalation therapy; controlled release; respiratory diseases

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advances in Parenteral Drug Delivery and Parenteral Formulations

edited by

Eduardo Ruiz-Hernandez

and Dorota Wątróbska-Świetlikowska

submission deadline 31 Mar 2026 | Viewed by 4 | Submission Open

Keywords: parenteral formulation; parenteral nutrition; injectable formulation; implants; intravenous; intramuscular; subcutaneous; long-acting injectables; nanosphere; submicron emulsion

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advanced Nanocarriers for Targeted Drug Delivery in Inflammation-Associated Diseases

edited by Ana Laura López-Machado and

Rossella Laurano

submission deadline 31 Mar 2026 | Viewed by 3 | Submission Open

Keywords: control release; drug delivery systems; inflammation-associated diseases; liposomes; micelles; nanocarriers; polymeric nanoparticles

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Displaying special issue 351-400 on page 8 of 10.

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